Strain Name:
C57BL/6J-MtgxR5429Btlr/Mmmh
Stock Number:
042995-MU
Citation ID:
RRID:MMRRC_042995-MU
Other Names:
R5429 (G1), C57BL/6J-MtgxR5429Btlr
Major Collection:

Gene Information

Pdpk1
Name: 3-phosphoinositide dependent protein kinase 1
Synonyms: Pkb kinase, Pdk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18607
HGNC: HGNC:8816
Homologene: 37643
Ppp2r2a
Name: protein phosphatase 2, regulatory subunit B, alpha
Synonyms: 2410004D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 71978
VEGA: 14
HGNC: HGNC:9304
Homologene: 2035
Herc4
Name: hect domain and RLD 4
Synonyms: 4921531D01Rik, 1700056O17Rik, 9530080M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67345
VEGA: 10
Homologene: 56715
Dock6
Name: dedicator of cytokinesis 6
Synonyms: 4931431C02Rik, C330023D02Rik, 2410095B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319899
VEGA: 9
Homologene: 83291
Ttc39b
Name: tetratricopeptide repeat domain 39B
Synonyms: 9130422G05Rik, 1810054D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 69863
Homologene: 25228
Btaf1
Name: B-TFIID TATA-box binding protein associated factor 1
Synonyms: E430027O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107182
Homologene: 31978
Ppp2r5e
Name: protein phosphatase 2, regulatory subunit B', epsilon
Synonyms: B56beta, 4633401M22Rik, protein phosphatase 2A subunit beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 26932
VEGA: 12
HGNC: HGNC:9313
Homologene: 55962
Auts2
Name: autism susceptibility candidate 2
Synonyms: 2700063G02Rik, A730011F23Rik, D830032G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 319974
Homologene: 22907
Safb
Name: scaffold attachment factor B
Synonyms: 3110021E02Rik, SAFB1, 5330423C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224903
Homologene: 2229
Zfp462
Name: zinc finger protein 462
Synonyms: Gt4-2, Zfpip, 9430078C22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242466
Homologene: 41430
Akap13
Name: A kinase (PRKA) anchor protein 13
Synonyms: PROTO-LB, Ht31, AKAP-Lbc, PROTO-LBC, 5730522G15Rik, 1700026G02Rik, 5830460E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 75547
HGNC: HGNC:371
Homologene: 4903
Nfx1
Name: nuclear transcription factor, X-box binding 1
Synonyms: 3000003M19Rik, Tex42, TEG-42, 1300017N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74164
HGNC: HGNC:7803
Homologene: 1875
Csde1
Name: cold shock domain containing E1, RNA binding
Synonyms: unr, D3Jfr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229663
Homologene: 5179
Slc30a7
Name: solute carrier family 30 (zinc transporter), member 7
Synonyms: 4833428C12Rik, ZnT7, 2610034N15Rik, 1810059J10Rik, ZnT-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66500
Homologene: 11332
Kat14
Name: lysine acetyltransferase 14
Synonyms: D2Ertd473e, D2Wsu131e, ATAC2, Csrp2bp, 2510008M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228714
Homologene: 10745
Scaf8
Name: SR-related CTD-associated factor 8
Synonyms: Rbm16, A630086M08Rik, A930036P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 106583
VEGA: 17
Homologene: 8928
Ctnnd1
Name: catenin (cadherin associated protein), delta 1
Synonyms: P120, Ctnnd, p120-catenin, Catns
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12388
HGNC: HGNC:2515
Homologene: 1017
Cit
Name: citron
Synonyms: Cit-k, C030025P15Rik, citron kinase, CRIK-SK, citron-N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12704
HGNC: HGNC:1985
Homologene: 21404
Rims2
Name: regulating synaptic membrane exocytosis 2
Synonyms: 2810036I15Rik, RIM2, Syt3-rs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 116838
VEGA: 15
Homologene: 81639
Kif13a
Name: kinesin family member 13A
Synonyms: N-3 kinesin, 4930505I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 16553
VEGA: 13
Homologene: 22589
Pi4kb
Name: phosphatidylinositol 4-kinase beta
Synonyms: Pik4cb, ESTM41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 107650
HGNC: HGNC:8984
Homologene: 6741
Zfp473
Name: zinc finger protein 473
Synonyms: D030014N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243963
Homologene: 18698
Tbc1d32
Name: TBC1 domain family, member 32
Synonyms: Bromi, C6orf170, D630037F22Rik, b2b2284Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 544696
VEGA: 10
Homologene: 51889
Tnrc6c
Name: trinucleotide repeat containing 6C
Synonyms: 9930033H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217351
Homologene: 23137
Tmem41a
Name: transmembrane protein 41a
Synonyms: 5730578N08Rik, 2900010K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 66664
VEGA: 16
Homologene: 41643
2410141K09Rik
Name: RIKEN cDNA 2410141K09 gene
Synonyms: Gt(Ayu21)35Imeg, Gt(pU21)35Imeg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 76803
Homologene: 136362
Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Synonyms: mtrp6, Trrp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22068
VEGA: 9
Homologene: 37944
Atp6v0a4
Name: ATPase, H+ transporting, lysosomal V0 subunit A4
Synonyms: Atp6n1b, V-ATPase alpha 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 140494
HGNC: HGNC:866
Homologene: 39904
Ghr
Name: growth hormone receptor
Synonyms: GHR/BP, GHBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14600
HGNC: HGNC:4263
Homologene: 134
Pcdh10
Name: protocadherin 10
Synonyms: 6430703F07Rik, OL-pc, 6430521D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18526
Homologene: 74967
Ciz1
Name: CDKN1A interacting zinc finger protein 1
Synonyms: 2900056O04Rik, 0610038H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68379
Homologene: 8112
Gbe1
Name: glucan (1,4-alpha-), branching enzyme 1
Synonyms: 2310045H19Rik, 2810426P10Rik, D16Ertd536e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 74185
HGNC: HGNC:4180
Homologene: 129
Myt1l
Name: myelin transcription factor 1-like
Synonyms: Png-1, C630034G21Rik, Nztf1, Pmng1, 2900046C06Rik, 2900093J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 17933
VEGA: 12
HGNC: HGNC:7623
Homologene: 7435
Kif2b
Name: kinesin family member 2B
Synonyms: 1700063D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 73470
Homologene: 23775
Mrps34
Name: mitochondrial ribosomal protein S34
Synonyms: 5330430D13Rik, 0610007F04Rik, Tce2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 79044
Homologene: 32562
Vil1
Name: villin 1
Synonyms: Villin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22349
Homologene: 5169
Sntb1
Name: syntrophin, basic 1
Synonyms: beta1-Syntrophin, 59-1 DAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20649
Homologene: 9618
Trim7
Name: tripartite motif-containing 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 94089
Homologene: 14113
Ankrd34a
Name: ankyrin repeat domain 34A
Synonyms: Ankrd34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 545554
Homologene: 82882
Slc9b1
Name: solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
Synonyms: 4933424B12Rik, 4933425K02Rik, 1700094G20Rik, Nhedc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74446
Homologene: 49914
Mboat1
Name: membrane bound O-acyltransferase domain containing 1
Synonyms: 9130215M02Rik, Oact1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218121
Homologene: 57467
Clca3b
Name: chloride channel accessory 3B
Synonyms: Clca4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229927
Homologene: 135610
Tmc1
Name: transmembrane channel-like gene family 1
Synonyms: Bth, 4933416G09Rik, Beethoven
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 13409
VEGA: 19
Homologene: 23670
Gm12789
Name: predicted gene 12789
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381536
Gm12500
Name: predicted gene 12500
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 791415
Gad1-ps
Name: glutamate decarboxylase 1, pseudogene
Synonyms: Gad-1ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 382407
VEGA: 10
Itih3
Name: inter-alpha trypsin inhibitor, heavy chain 3
Synonyms: Intin3, Itih-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16426
HGNC: HGNC:6168
Homologene: 1669
Olfr60
Name: olfactory receptor 60
Synonyms: MOR253-6, IH6, GA_x6K02T2PBJ9-42496183-42495251
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18361
Homologene: 34961
Rpusd4
Name: RNA pseudouridylate synthase domain containing 4
Synonyms: 2410001E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71989
Homologene: 32794
Olfr318
Name: olfactory receptor 318
Synonyms: MOR285-1, GA_x6K02T2NKPP-692816-693736
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258494
Homologene: 133825
Csrnp2
Name: cysteine-serine-rich nuclear protein 2
Synonyms: CSRNP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 207785
VEGA: 15
Homologene: 32743
Mfsd1
Name: major facilitator superfamily domain containing 1
Synonyms: 1200003O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66868
Homologene: 11228
Filip1l
Name: filamin A interacting protein 1-like
Synonyms: 4631422O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 78749
Homologene: 37121
Gm10770
Name: predicted gene 10770
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 544945
VEGA: 2
Tlnrd1
Name: talin rod domain containing 1
Synonyms: Mesdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 80889
Homologene: 11209
Vmn2r-ps36
Name: vomeronasal 2, receptor, pseudogene 36
Synonyms: EG665442
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 665442
2810032G03Rik
Name: RIKEN cDNA 2810032G03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 72669
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 74,432,331 bp
  • T to A, chromosome 2 at 32,376,043 bp
  • C to T, chromosome 2 at 84,616,789 bp
  • T to A, chromosome 2 at 144,393,323 bp
  • C to T, chromosome 2 at 150,179,423 bp
  • T to C, chromosome 3 at 45,384,200 bp
  • T to A, chromosome 3 at 67,599,960 bp
  • A to T, chromosome 3 at 95,004,339 bp
  • G to A, chromosome 3 at 96,597,521 bp
  • A to G, chromosome 3 at 103,052,841 bp
  • A to G, chromosome 3 at 108,086,652 bp
  • A to G, chromosome 3 at 116,006,925 bp
  • T to C, chromosome 3 at 135,373,263 bp
  • C to T, chromosome 3 at 144,846,459 bp
  • T to C, chromosome 4 at 41,004,343 bp
  • T to C, chromosome 4 at 55,060,077 bp
  • A to G, chromosome 4 at 83,243,953 bp
  • T to C, chromosome 4 at 101,989,961 bp
  • A to T, chromosome 5 at 115,886,650 bp
  • G to A, chromosome 5 at 131,472,335 bp
  • A to C, chromosome 6 at 38,048,988 bp
  • A to G, chromosome 7 at 7,417,792 bp
  • T to A, chromosome 7 at 44,732,848 bp
  • T to G, chromosome 7 at 75,602,904 bp
  • G to T, chromosome 7 at 83,882,314 bp
  • A to G, chromosome 7 at 140,345,273 bp
  • C to T, chromosome 9 at 8,634,074 bp
  • T to C, chromosome 9 at 21,832,881 bp
  • T to C, chromosome 9 at 35,272,602 bp
  • T to C, chromosome 10 at 56,027,993 bp
  • T to A, chromosome 10 at 63,275,013 bp
  • G to A, chromosome 10 at 99,445,147 bp
  • G to A, chromosome 11 at 48,849,955 bp
  • T to A, chromosome 11 at 58,720,524 bp
  • A to G, chromosome 11 at 91,577,229 bp
  • C to T, chromosome 11 at 117,733,752 bp
  • A to T, chromosome 12 at 5,415,106 bp
  • G to A, chromosome 12 at 29,832,332 bp
  • T to A, chromosome 12 at 75,453,763 bp
  • A to G, chromosome 13 at 30,219,667 bp
  • A to G, chromosome 13 at 46,772,769 bp
  • G to A, chromosome 13 at 66,431,828 bp
  • A to G, chromosome 14 at 30,923,521 bp
  • A to T, chromosome 14 at 67,023,756 bp
  • G to A, chromosome 15 at 3,388,675 bp
  • A to T, chromosome 15 at 39,345,355 bp
  • C to G, chromosome 15 at 55,642,795 bp
  • A to G, chromosome 15 at 100,482,054 bp
  • A to G, chromosome 16 at 21,934,856 bp
  • A to T, chromosome 16 at 57,570,255 bp
  • A to C, chromosome 16 at 70,360,939 bp
  • C to A, chromosome 17 at 3,197,110 bp
  • T to C, chromosome 17 at 24,091,560 bp
  • T to C, chromosome 17 at 24,895,148 bp
  • T to C, chromosome 17 at 56,588,822 bp
  • G to T, chromosome 19 at 20,789,622 bp
  • G to A, chromosome 19 at 36,994,857 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5429 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042995-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.