Strain Name:
C57BL/6J-MtgxR5468Btlr/Mmmh
Stock Number:
043029-MU
Citation ID:
RRID:MMRRC_043029-MU
Other Names:
R5468 (G1), C57BL/6J-MtgxR5468Btlr
Major Collection:

Gene Information

Sfrp1
Name: secreted frizzled-related protein 1
Synonyms: sFRP-1, 2210415K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20377
Homologene: 2266
Fubp3
Name: far upstream element (FUSE) binding protein 3
Synonyms: FBP3, A330051M14Rik, Marta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320267
HGNC: HGNC:4005
Homologene: 45954
Plcb4
Name: phospholipase C, beta 4
Synonyms: C230058B11Rik, A930039J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18798
HGNC: HGNC:9059
Homologene: 8471
Tnpo3
Name: transportin 3
Synonyms: 5730544L10Rik, C430013M08Rik, D6Ertd313e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320938
Homologene: 40848
Zfp553
Name: zinc finger protein 553
Synonyms: C330013F15Rik, 2600009K23Rik, ENSMUSG00000054461
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233887
Homologene: 27098
Ppm1e
Name: protein phosphatase 1E (PP2C domain containing)
Synonyms: PP2CH, POPX1, B930008A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 320472
Homologene: 22848
Fry
Name: FRY microtubule binding protein
Synonyms: cg003, 9330186A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320365
Homologene: 113770
Zfp619
Name: zinc finger protein 619
Synonyms: 3000002G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70227
Homologene: 133818
Wls
Name: wntless WNT ligand secretion mediator
Synonyms: 5031439A09Rik, Gpr177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68151
Homologene: 11779
Nbr1
Name: NBR1, autophagy cargo receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17966
HGNC: HGNC:6746
Homologene: 7438
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, Lek1, mitosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Zfp985
Name: zinc finger protein 985
Synonyms: Gm13154
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 433804
Homologene: 133076
Gbf1
Name: golgi-specific brefeldin A-resistance factor 1
Synonyms: 1700083E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107338
HGNC: HGNC:4181
Homologene: 37897
Rif1
Name: replication timing regulatory factor 1
Synonyms: 5730435J01Rik, 6530403D07Rik, D2Ertd145e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 51869
Homologene: 41231
Tenm2
Name: teneurin transmembrane protein 2
Synonyms: Ten-m2, D3Bwg1534e, 9330187F13Rik, 2610040L17Rik, Odz2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 23964
Homologene: 22672
Adam12
Name: a disintegrin and metallopeptidase domain 12 (meltrin alpha)
Synonyms: Mltna, ADAM12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11489
HGNC: HGNC:190
Homologene: 74862
Onecut1
Name: one cut domain, family member 1
Synonyms: HNF6, Hnf6, Hfh12, D9Ertd423e, Oc1, OC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 15379
HGNC: HGNC:8138
Homologene: 3309
Lypd8
Name: LY6/PLAUR domain containing 8
Synonyms: 2210415F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70163
Homologene: 52815
Plekhm2
Name: pleckstrin homology domain containing, family M (with RUN domain) member 2
Synonyms: 2310034J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69582
Homologene: 19575
Mtus1
Name: mitochondrial tumor suppressor 1
Synonyms: MD44, MTSG1, Atip1, B430305I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102103
Homologene: 100292
Ppwd1
Name: peptidylprolyl isomerase domain and WD repeat containing 1
Synonyms: A330090G21Rik, 4632422M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238831
VEGA: 13
Homologene: 9099
Tspan18
Name: tetraspanin 18
Synonyms: 2610042G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241556
Homologene: 24122
Abca16
Name: ATP-binding cassette, sub-family A (ABC1), member 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233810
Homologene: 132942
Rbp3
Name: retinol binding protein 3, interstitial
Synonyms: Irbp, Rbp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19661
VEGA: 14
HGNC: HGNC:9921
Homologene: 9261
Wnt16
Name: wingless-type MMTV integration site family, member 16
Synonyms: E130309I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 93735
Homologene: 62175
Slc35e2
Name: solute carrier family 35, member E2
Synonyms: A530082C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 320541
Homologene: 84987
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Pigo
Name: phosphatidylinositol glycan anchor biosynthesis, class O
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56703
Homologene: 31761
Adamts4
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
Synonyms: aggrecanase-1, ADAM-TS4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240913
HGNC: HGNC:220
Homologene: 36169
Cfap74
Name: cilia and flagella associated protein 74
Synonyms: 2010015L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 544678
Homologene: 129584
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26875
Homologene: 69111
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Tmprss7
Name: transmembrane serine protease 7
Synonyms: LOC385645, B230219I23Rik, matriptase-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208171
Homologene: 18178
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Trim16
Name: tripartite motif-containing 16
Synonyms: EBBP, 9130006M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 94092
Homologene: 4726
Nlrp9c
Name: NLR family, pyrin domain containing 9C
Synonyms: Nalp9c, Nalp-zeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330490
Homologene: 116072
Rubcnl
Name: RUN and cysteine rich domain containing beclin 1 interacting protein like
Synonyms: LOC380917, 5031414D18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 271221
VEGA: 14
Homologene: 57021
Nfatc1
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
Synonyms: NFAT2, NFATc, NF-ATc, 2210017P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 18018
VEGA: 18
HGNC: HGNC:7775
Homologene: 32336
Impg1
Name: interphotoreceptor matrix proteoglycan 1
Synonyms: IMP150, SPACR, A930015H12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 63859
HGNC: HGNC:6055
Homologene: 1201
Atp7b
Name: ATPase, Cu++ transporting, beta polypeptide
Synonyms: WND, Wilson protein, Atp7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11979
HGNC: HGNC:870
Homologene: 20063
Lipm
Name: lipase, family member M
Synonyms: 4632427C23Rik, Lipl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 78753
VEGA: 19
Homologene: 28267
Uroc1
Name: urocanase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243537
Homologene: 76629
Tril
Name: TLR4 interactor with leucine-rich repeats
Synonyms: 1200009O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66873
Homologene: 69404
Anxa1
Name: annexin A1
Synonyms: Lpc-1, Lpc1, Anx-1, Anx-A1, C430014K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16952
HGNC: HGNC:533
Homologene: 563
Cep162
Name: centrosomal protein 162
Synonyms: 4922501C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382090
Homologene: 8930
Fetub
Name: fetuin beta
Synonyms: 2310011O17Rik, D17980
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 59083
VEGA: 16
HGNC: HGNC:3658
Homologene: 8660
Nlrc3
Name: NLR family, CARD domain containing 3
Synonyms: D230007K08Rik, Caterpiller 16.2, CLR16.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268857
Homologene: 18720
Myo3b
Name: myosin IIIB
Synonyms: A430065P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329421
Homologene: 51393
Zmynd15
Name: zinc finger, MYND-type containing 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 574428
Homologene: 12995
Olfr340
Name: olfactory receptor 340
Synonyms: GA_x6K02T2NLDC-33147742-33148680, MOR136-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258953
Homologene: 74159
Adrb2
Name: adrenergic receptor, beta 2
Synonyms: beta 2-AR, Badm, Adrb-2, beta 2-adrenoceptor, Gpcr7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 11555
VEGA: 18
HGNC: HGNC:286
Homologene: 30948
Dglucy
Name: D-glutamate cyclase
Synonyms: 9030617O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217830
Homologene: 11798
Man2a2
Name: mannosidase 2, alpha 2
Synonyms: alpha mannosidase IIx, MX, 4931438M07Rik, 1700052O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 140481
HGNC: HGNC:6825
Homologene: 55954
Qrich2
Name: glutamine rich 2
Synonyms: LOC217341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217341
Homologene: 12951
Olfr951
Name: olfactory receptor 951
Synonyms: GA_x6K02T2PVTD-33090395-33091330, MOR171-49, MOR171-33P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258046
VEGA: 9
Homologene: 71961
Zmynd10
Name: zinc finger, MYND domain containing 10
Synonyms: Blu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 114602
Homologene: 9293
Sec14l5
Name: SEC14-like lipid binding 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 665119
VEGA: 16
Homologene: 96163
Cntn5
Name: contactin 5
Synonyms: LOC244683, NB-2, A830025P08Rik, 6720426O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244682
HGNC: HGNC:2175
Homologene: 28447
Olfr881
Name: olfactory receptor 881
Synonyms: GA_x6K02T2PVTD-31676771-31677700, MOR162-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258413
Homologene: 74013
Apba2
Name: amyloid beta (A4) precursor protein-binding, family A, member 2
Synonyms: X11-like, X11L, Mint 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11784
HGNC: HGNC:579
Homologene: 4021
Atpsckmt
Name: ATP synthase C subunit lysine N-methyltransferase
Synonyms: A930016P21Rik, Fam173b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68073
Homologene: 16780
Fam184a
Name: family with sequence similarity 184, member A
Synonyms: 3110012E06Rik, 4930438C08Rik, 4930589M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 75906
Homologene: 11600
Pccb
Name: propionyl Coenzyme A carboxylase, beta polypeptide
Synonyms: 1300012P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66904
HGNC: HGNC:8654
Homologene: 447
Fam186b
Name: family with sequence similarity 186, member B
Synonyms: EG545136
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 545136
VEGA: 15
Homologene: 69502
C2cd2
Name: C2 calcium-dependent domain containing 2
Synonyms: ORF25, 5830404H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207781
VEGA: 16
HGNC: HGNC:1266
Homologene: 18368
Itfg2
Name: integrin alpha FG-GAP repeat containing 2
Synonyms: 2700050P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 101142
Homologene: 10211
Man2b2
Name: mannosidase 2, alpha B2
Synonyms: 135 kDa alpha-D-mannosidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17160
Homologene: 7411
Arsj
Name: arylsulfatase J
Synonyms: 9330196J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 271970
Homologene: 35257
Gm12689
Name: predicted gene 12689
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Arhgap18
Name: Rho GTPase activating protein 18
Synonyms: 4833419J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 73910
Homologene: 14135
Acp2
Name: acid phosphatase 2, lysosomal
Synonyms: Acp-2, LAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11432
HGNC: HGNC:123
Homologene: 1217
Cracd
Name: capping protein inhibiting regulator of actin
Synonyms: C530008M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320827
Homologene: 136278
Sepsecs
Name: Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
Synonyms: SLA, D5Ertd135e, SecS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 211006
Homologene: 15031
Sh3tc2
Name: SH3 domain and tetratricopeptide repeats 2
Synonyms: D430044G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225608
VEGA: 18
Homologene: 11596
Prss29
Name: protease, serine 29
Synonyms: mISP-2, Isp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 114662
VEGA: 17
Homologene: 70877
Prss27
Name: protease, serine 27
Synonyms: marapsin, CAPH2, Mpn, Pancreasin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 213171
Homologene: 23743
Ms4a7
Name: membrane-spanning 4-domains, subfamily A, member 7
Synonyms: 9130422I10Rik, CFFMA, CD20l4, A430103C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 109225
Homologene: 10922
1700008O03Rik
Name: RIKEN cDNA 1700008O03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69349
Homologene: 19260
Hemk1
Name: HemK methyltransferase family member 1
Synonyms: 2310008M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69536
Homologene: 6815
Fam181a
Name: family with sequence similarity 181, member A
Synonyms: EG544888
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 100504156
Homologene: 34701
Gm10999
Name: predicted gene 10999
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 171,252,609 bp
  • A to T, chromosome 1 at 189,652,371 bp
  • A to G, chromosome 2 at 31,603,235 bp
  • A to T, chromosome 2 at 36,453,443 bp
  • T to C, chromosome 2 at 52,094,616 bp
  • A to G, chromosome 2 at 70,234,441 bp
  • T to A, chromosome 2 at 91,206,098 bp
  • T to C, chromosome 2 at 93,209,862 bp
  • T to C, chromosome 2 at 135,967,152 bp
  • T to C, chromosome 3 at 126,438,388 bp
  • A to G, chromosome 3 at 159,839,919 bp
  • C to T, chromosome 4 at 43,024,562 bp
  • T to C, chromosome 4 at 99,296,165 bp
  • G to T, chromosome 4 at 141,628,100 bp
  • A to G, chromosome 4 at 147,583,245 bp
  • A to T, chromosome 4 at 155,426,041 bp
  • C to T, chromosome 4 at 155,610,026 bp
  • A to T, chromosome 5 at 14,680,952 bp
  • A to G, chromosome 5 at 36,807,175 bp
  • A to T, chromosome 5 at 52,644,014 bp
  • A to T, chromosome 5 at 76,840,763 bp
  • C to A, chromosome 5 at 124,830,493 bp
  • A to T, chromosome 5 at 150,399,588 bp
  • T to C, chromosome 6 at 22,291,161 bp
  • C to T, chromosome 6 at 29,585,993 bp
  • T to C, chromosome 6 at 53,819,647 bp
  • A to T, chromosome 6 at 90,338,604 bp
  • GGAGAGAGAGAGAGAGAGA to GGAGAGAGAGAGAGAGA, chromosome 6 at 128,416,068 bp
  • A to T, chromosome 7 at 26,365,000 bp
  • C to T, chromosome 7 at 39,535,728 bp
  • C to T, chromosome 7 at 44,360,235 bp
  • T to C, chromosome 7 at 64,745,762 bp
  • T to C, chromosome 7 at 80,352,981 bp
  • C to T, chromosome 7 at 120,475,524 bp
  • T to C, chromosome 7 at 127,237,030 bp
  • T to C, chromosome 7 at 133,975,473 bp
  • A to T, chromosome 8 at 22,059,970 bp
  • A to G, chromosome 8 at 23,446,210 bp
  • A to G, chromosome 8 at 41,084,578 bp
  • G to A, chromosome 8 at 129,131,649 bp
  • A to G, chromosome 9 at 9,743,628 bp
  • G to A, chromosome 9 at 37,993,011 bp
  • A to G, chromosome 9 at 39,393,961 bp
  • A to T, chromosome 9 at 74,863,332 bp
  • T to C, chromosome 9 at 80,465,265 bp
  • A to C, chromosome 9 at 87,227,237 bp
  • T to A, chromosome 9 at 100,985,131 bp
  • C to T, chromosome 9 at 107,330,746 bp
  • T to A, chromosome 9 at 107,550,337 bp
  • T to A, chromosome 10 at 26,912,671 bp
  • A to G, chromosome 10 at 39,072,682 bp
  • A to G, chromosome 10 at 53,647,114 bp
  • T to A, chromosome 11 at 9,294,062 bp
  • C to A, chromosome 11 at 36,300,222 bp
  • T to C, chromosome 11 at 58,386,760 bp
  • T to C, chromosome 11 at 62,840,978 bp
  • T to C, chromosome 11 at 70,461,820 bp
  • T to A, chromosome 11 at 87,230,890 bp
  • A to T, chromosome 11 at 101,572,464 bp
  • T to A, chromosome 11 at 116,448,365 bp
  • A to G, chromosome 12 at 100,850,335 bp
  • A to T, chromosome 12 at 103,316,678 bp
  • A to G, chromosome 13 at 104,225,444 bp
  • A to T, chromosome 14 at 33,956,627 bp
  • G to A, chromosome 14 at 75,032,031 bp
  • A to G, chromosome 15 at 31,603,457 bp
  • A to G, chromosome 15 at 99,278,870 bp
  • A to C, chromosome 16 at 3,964,035 bp
  • A to G, chromosome 16 at 5,167,140 bp
  • C to T, chromosome 16 at 22,932,331 bp
  • A to G, chromosome 16 at 45,656,448 bp
  • C to T, chromosome 16 at 97,868,591 bp
  • C to A, chromosome 17 at 24,038,313 bp
  • T to A, chromosome 17 at 25,321,046 bp
  • G to A, chromosome 18 at 61,973,431 bp
  • A to T, chromosome 18 at 62,179,625 bp
  • C to T, chromosome 18 at 80,649,855 bp
  • C to T, chromosome 19 at 11,322,414 bp
  • A to T, chromosome 19 at 20,378,483 bp
  • T to A, chromosome 19 at 34,109,554 bp
  • A to G, chromosome 19 at 46,284,296 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5468 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043029-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.