Beutler Mutagenetix

Strain Name:
C57BL/6J-MtgxR5894Btlr/Mmmh
Stock Number:
043238-MU
Citation ID:
RRID:MMRRC_043238-MU
Other Names:
R5894 (G1), C57BL/6J-MtgxR5894Btlr
Major Collection:

Gene Information

Shprh
Name: SNF2 histone linker PHD RING helicase
Synonyms: D230017O13Rik, 2610103K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 268281
Homologene: 6489
Sptbn1
Name: spectrin beta, non-erythrocytic 1
Synonyms: non-erythrocytic, spectrin G, Spnb-2, Spnb2, beta fodrin, brain spectrin, elf3, elf1, 9930031C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20742
Homologene: 2354
Grm1
Name: glutamate receptor, metabotropic 1
Synonyms: rcw, nmf373, mGluR1, Grm1, Gprc1a, 4930455H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14816
HGNC: HGNC:4593
Homologene: 649
Sgcd
Name: sarcoglycan, delta (dystrophin-associated glycoprotein)
Synonyms: delta-SG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 24052
Homologene: 285
Ndrg3
Name: N-myc downstream regulated gene 3
Synonyms: Ndr3, 4833415O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 29812
Homologene: 40903
Crlf3
Name: cytokine receptor-like factor 3
Synonyms: cytor4, Creme9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 54394
Homologene: 9327
Scrib
Name: scribbled planar cell polarity
Synonyms: Crc, Scrb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105782
Homologene: 44228
Tac2
Name: tachykinin 2
Synonyms: neurokinin A, neuromedin L, neuropeptide K, neurokinin alpha, substance K, neurokinin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 21334
VEGA: 10
Homologene: 7560
Rbm6
Name: RNA binding motif protein 6
Synonyms: NY-LU-12, Def-3, g16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 19654
HGNC: HGNC:9903
Homologene: 31336
Ddx5
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
Synonyms: Hlr1, p68, 2600009A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 13207
HGNC: HGNC:2746
Homologene: 6797
Tars2
Name: threonyl-tRNA synthetase 2, mitochondrial (putative)
Synonyms: Tarsl1, 2610024N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71807
Homologene: 23520
Trpc4ap
Name: transient receptor potential cation channel, subfamily C, member 4 associated protein
Synonyms: 4833429F06Rik, D2Ertd113e, Trrp4ap, Trp4-associated protein TAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56407
Homologene: 9224
Afdn
Name: afadin, adherens junction formation factor
Synonyms: AF6, S-afadin, Mllt4, I-afadin, 5033403D15Rik, Afadin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17356
HGNC: HGNC:7137
Homologene: 21202
Plcg2
Name: phospholipase C, gamma 2
Synonyms: PLCgamma2, Plcg-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234779
HGNC: HGNC:9066
Homologene: 55671
Lpin2
Name: lipin 2
Synonyms: 2610511G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 64898
Homologene: 8769
Ints12
Name: integrator complex subunit 12
Synonyms: 1110020M19Rik, A230056J18Rik, 4930529N21Rik, Phf22, 2810027J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71793
Homologene: 32474
Usp53
Name: ubiquitin specific peptidase 53
Synonyms: mbo, Phxr3, Sp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99526
Homologene: 34521
Pex1
Name: peroxisomal biogenesis factor 1
Synonyms: peroxisome biogenesis factor 1, 5430414H02Rik, E330005K07Rik, ZWS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71382
HGNC: HGNC:8850
Homologene: 27006
Frs2
Name: fibroblast growth factor receptor substrate 2
Synonyms: Frs2alpha, C330018A15Rik, SNT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 327826
VEGA: 10
Homologene: 4846
Tefm
Name: transcription elongation factor, mitochondrial
Synonyms: FLJ22729, 1110002N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 68550
Homologene: 11657
Rxrb
Name: retinoid X receptor beta
Synonyms: Nr2b2, Rub, RCoR-1, H-2RIIBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20182
Homologene: 7923
Atp6v1b2
Name: ATPase, H+ transporting, lysosomal V1 subunit B2
Synonyms: HO57, Atp6b2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11966
HGNC: HGNC:854
Homologene: 1279
Grid2ip
Name: glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
Synonyms: delphilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 170935
Homologene: 15781
Scyl2
Name: SCY1-like 2 (S. cerevisiae)
Synonyms: CVAK104, D10Ertd802e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 213326
Homologene: 13349
Xpot
Name: exportin, tRNA (nuclear export receptor for tRNAs)
Synonyms: EXPORTIN-T, 1110004L07Rik, C79645
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 73192
VEGA: 10
Homologene: 38291
Kank1
Name: KN motif and ankyrin repeat domains 1
Synonyms: Ankrd15, D330024H06Rik, A930031B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107351
Homologene: 17706
Cdh9
Name: cadherin 9
Synonyms: T1-cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12565
HGNC: HGNC:1768
Homologene: 9450
Prune2
Name: prune homolog 2
Synonyms: 6330414G02Rik, A230083H22Rik, A330102H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 353211
VEGA: 19
Homologene: 18939
Rbm43
Name: RNA binding motif protein 43
Synonyms: 0610033I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71684
Homologene: 12715
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Bcl9
Name: B cell CLL/lymphoma 9
Synonyms: A330041G23Rik, 2610202E01Rik, 8030475K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77578
HGNC: HGNC:1008
Homologene: 3191
Amotl2
Name: angiomotin-like 2
Synonyms: Lccp, MASCOT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 56332
Homologene: 9420
Trim37
Name: tripartite motif-containing 37
Synonyms: MUL, TEF3, 2810004E07Rik, 1110032A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 68729
HGNC: HGNC:7523
Homologene: 9084
Rnf214
Name: ring finger protein 214
Synonyms: D130054N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235315
Homologene: 109357
Fchsd2
Name: FCH and double SH3 domains 2
Synonyms: Sh3md3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 207278
Homologene: 8887
Csdc2
Name: cold shock domain containing C2, RNA binding
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105859
Homologene: 8701
Stag3
Name: stromal antigen 3
Synonyms: stromalin 3, SA-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 50878
Homologene: 40844
Sohlh1
Name: spermatogenesis and oogenesis specific basic helix-loop-helix 1
Synonyms: LOC227631, NOHLH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227631
Homologene: 45955
Csk
Name: c-src tyrosine kinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12988
VEGA: 9
HGNC: HGNC:2444
Homologene: 55818
Slc22a4
Name: solute carrier family 22 (organic cation transporter), member 4
Synonyms: Octn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 30805
Homologene: 81701
Mx1
Name: MX dynamin-like GTPase 1
Synonyms: Mx, myxovirus (influenza) resistance 1 polypeptide, Mx-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 17857
Homologene: null
Fbxw18
Name: F-box and WD-40 domain protein 18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 546161
Homologene: 110776
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244484
Homologene: 12460
Ptpdc1
Name: protein tyrosine phosphatase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218232
VEGA: 13
Homologene: 17576
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 545030
Homologene: 83473
Gm1966
Name: predicted gene 1966
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434223
HGNC: null
Homologene: 32708
Unc13c
Name: unc-13 homolog C
Synonyms: Munc13-3, 1500037O19Rik, D9Ertd414e, Unc13h3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 208898
Homologene: 45443
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Slc44a5
Name: solute carrier family 44, member 5
Synonyms: LOC242259
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242259
Homologene: 72094
Adcy2
Name: adenylate cyclase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 210044
VEGA: 13
HGNC: HGNC:233
Homologene: 75133
Usp35
Name: ubiquitin specific peptidase 35
Synonyms: LOC244144, LOC381901
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244144
Homologene: 35459
Insr
Name: insulin receptor
Synonyms: IR, IR-B, D630014A15Rik, 4932439J01Rik, CD220, IR-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16337
HGNC: HGNC:6091
Homologene: 20090
Ankhd1
Name: ankyrin repeat and KH domain containing 1
Synonyms: 9130019P20Rik, 1110004O12Rik, 4933432B13Rik, A530027J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 108857
Homologene: 87006
Arntl2
Name: aryl hydrocarbon receptor nuclear translocator-like 2
Synonyms: bHLHe6, MOP9, BMAL2, 4632430A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 272322
Homologene: 10609
Oas3
Name: 2'-5' oligoadenylate synthetase 3
Synonyms: Oasl10, 2'-5' oligoadenylate synthetase-like 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 246727
HGNC: HGNC:8088
Homologene: 4510
Cog2
Name: component of oligomeric golgi complex 2
Synonyms: Cog2, 2700012E02Rik, 1190002B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 76332
HGNC: HGNC:6546
Homologene: 7206
Alpk2
Name: alpha-kinase 2
Synonyms: Hak
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225638
Homologene: 50475
Ift140
Name: intraflagellar transport 140
Synonyms: Tce5, Wdtc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 106633
Homologene: 40979
Olfr1216
Name: olfactory receptor 1216
Synonyms: MOR233-9, GA_x6K02T2Q125-50494588-50493653
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258895
HGNC: null
Homologene: 74241
Bpifb4
Name: BPI fold containing family B, member 4
Synonyms: LOC381399, Gm1006
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381399
Homologene: 66971
Csmd2
Name: CUB and Sushi multiple domains 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 329942
Homologene: 89034
Slc13a3
Name: solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
Synonyms: SDCT2, NaDC3, NaDC-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 114644
Homologene: 11266
Spata20
Name: spermatogenesis associated 20
Synonyms: Tisp78
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217116
Homologene: 11264
Ces2h
Name: carboxylesterase 2H
Synonyms: Gm5744
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 436059
HGNC: HGNC:1864
Homologene: 128645
Vstm2a
Name: V-set and transmembrane domain containing 2A
Synonyms: Vstm2, 9330184N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 211739
Homologene: 17123
Miip
Name: migration and invasion inhibitory protein
Synonyms: D4Wsu114e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 28010
Homologene: 15879
4930503B20Rik
Name: RIKEN cDNA 4930503B20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 75015
HGNC: null
Homologene: 41344
Vmn1r80
Name: vomeronasal 1 receptor 80
Synonyms: V1rg3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 171238
HGNC: null
Homologene: null
Ccdc144b
Name: coiled-coil domain containing 144B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 241943
HGNC: null
Homologene: 87263
Musk
Name: muscle, skeletal, receptor tyrosine kinase
Synonyms: MDK4, Nsk1, Nsk3, Nsk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18198
HGNC: HGNC:7525
Homologene: 4084
Cyp2c29
Name: cytochrome P450, family 2, subfamily c, polypeptide 29
Synonyms: Ah-2, AHOH, AHOHase, Ahh-1, P450-2C, Cyp2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 13095
HGNC: HGNC:2622
Homologene: 117948
Tmem82
Name: transmembrane protein 82
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 213989
Homologene: 27088
Psme1
Name: proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
Synonyms: PA28a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19186
HGNC: HGNC:9568
Homologene: 4560
Kng1
Name: kininogen 1
Synonyms: H-kininigen, L-kininogen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 16644
HGNC: HGNC:6383
Homologene: 88343
Olfr791
Name: olfactory receptor 791
Synonyms: MOR114-1, GA_x6K02T2PULF-11205096-11206034
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258932
Homologene: 71950
Ddx43
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
Synonyms: OTTMUSG00000019690, ENSMUSG00000070291
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 100048658
Homologene: 56814
Olfr1255
Name: olfactory receptor 1255
Synonyms: MOR232-4, GA_x6K02T2Q125-51257221-51258135
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258979
Homologene: 82298
Usp18
Name: ubiquitin specific peptidase 18
Synonyms: UBP43, 1110058H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 24110
Homologene: 8047
Trem3
Name: triggering receptor expressed on myeloid cells 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 58218
VEGA: 17
HGNC: null
Homologene: 87012
Gm7135
Name: predicted gene 7135
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 634346
HGNC: null
Homologene: 86643
Arl14
Name: ADP-ribosylation factor-like 14
Synonyms: 9130014L17Rik, Arf7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71619
Homologene: 11812
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 97,469,927 bp
  • A to G, chromosome 2 at 25,844,667 bp
  • A to T, chromosome 2 at 41,498,221 bp
  • A to G, chromosome 2 at 51,926,798 bp
  • T to A, chromosome 2 at 89,014,055 bp
  • T to C, chromosome 2 at 89,817,213 bp
  • G to A, chromosome 2 at 153,940,932 bp
  • T to C, chromosome 2 at 155,666,213 bp
  • A to T, chromosome 2 at 156,928,778 bp
  • C to T, chromosome 2 at 165,424,623 bp
  • C to T, chromosome 3 at 36,019,975 bp
  • T to C, chromosome 3 at 69,222,676 bp
  • T to C, chromosome 3 at 95,747,652 bp
  • T to C, chromosome 3 at 97,215,368 bp
  • A to G, chromosome 3 at 122,959,085 bp
  • A to T, chromosome 3 at 133,098,558 bp
  • T to A, chromosome 3 at 146,650,925 bp
  • A to G, chromosome 3 at 154,256,573 bp
  • G to A, chromosome 4 at 58,373,583 bp
  • C to A, chromosome 4 at 128,369,074 bp
  • G to A, chromosome 4 at 141,616,211 bp
  • G to A, chromosome 4 at 147,862,608 bp
  • T to A, chromosome 5 at 3,620,590 bp
  • G to A, chromosome 5 at 120,756,954 bp
  • T to G, chromosome 5 at 138,298,838 bp
  • A to T, chromosome 5 at 143,388,911 bp
  • A to G, chromosome 6 at 121,261,497 bp
  • A to G, chromosome 6 at 146,823,234 bp
  • A to T, chromosome 7 at 12,193,727 bp
  • T to A, chromosome 7 at 97,313,077 bp
  • C to T, chromosome 7 at 101,191,752 bp
  • T to A, chromosome 7 at 106,601,427 bp
  • A to G, chromosome 8 at 3,174,869 bp
  • T to A, chromosome 8 at 54,696,300 bp
  • T to A, chromosome 8 at 69,107,566 bp
  • T to G, chromosome 8 at 105,019,026 bp
  • A to G, chromosome 8 at 117,504,349 bp
  • T to C, chromosome 8 at 124,545,267 bp
  • A to G, chromosome 9 at 45,866,618 bp
  • A to C, chromosome 9 at 57,628,675 bp
  • C to T, chromosome 9 at 73,693,204 bp
  • G to A, chromosome 9 at 78,416,734 bp
  • T to A, chromosome 9 at 102,725,172 bp
  • A to T, chromosome 9 at 107,860,322 bp
  • G to T, chromosome 9 at 109,700,167 bp
  • A to G, chromosome 10 at 11,080,255 bp
  • A to G, chromosome 10 at 11,207,796 bp
  • A to G, chromosome 10 at 89,640,819 bp
  • T to A, chromosome 10 at 117,081,106 bp
  • T to C, chromosome 10 at 121,613,646 bp
  • A to G, chromosome 10 at 127,726,102 bp
  • A to G, chromosome 10 at 129,526,488 bp
  • A to T, chromosome 11 at 16,261,483 bp
  • C to T, chromosome 11 at 30,100,613 bp
  • A to G, chromosome 11 at 47,355,201 bp
  • A to T, chromosome 11 at 53,997,515 bp
  • T to A, chromosome 11 at 80,057,852 bp
  • G to A, chromosome 11 at 80,140,231 bp
  • G to T, chromosome 11 at 87,201,440 bp
  • T to C, chromosome 11 at 94,483,618 bp
  • A to C, chromosome 11 at 106,785,205 bp
  • A to G, chromosome 13 at 48,590,322 bp
  • A to T, chromosome 13 at 68,625,852 bp
  • T to A, chromosome 14 at 33,133,360 bp
  • T to C, chromosome 14 at 55,580,687 bp
  • T to A, chromosome 15 at 16,832,100 bp
  • T to C, chromosome 15 at 76,067,732 bp
  • T to A, chromosome 15 at 81,948,680 bp
  • T to A, chromosome 16 at 23,073,363 bp
  • C to T, chromosome 16 at 97,454,206 bp
  • T to C, chromosome 17 at 13,899,196 bp
  • T to C, chromosome 17 at 25,033,919 bp
  • T to A, chromosome 17 at 34,035,744 bp
  • T to C, chromosome 17 at 48,258,455 bp
  • A to T, chromosome 17 at 67,779,047 bp
  • A to G, chromosome 17 at 71,246,934 bp
  • T to A, chromosome 18 at 36,647,524 bp
  • T to A, chromosome 18 at 65,281,072 bp
  • A to T, chromosome 19 at 17,121,391 bp
  • A to G, chromosome 19 at 25,424,200 bp
  • G to C, chromosome 19 at 39,330,389 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5894 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043238-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.