Strain Name:
C57BL/6J-MtgxR6036Btlr/Mmmh
Stock Number:
043257-MU
Citation ID:
RRID:MMRRC_043257-MU
Other Names:
R6036 (G1), C57BL/6J-MtgxR6036Btlr
Major Collection:

Gene Information

Gtf2h3
Name: general transcription factor IIH, polypeptide 3
Synonyms: BTF2, D5Ertd679e, 5033417D07Rik, 34kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 209357
HGNC: HGNC:4657
Homologene: 1160
Nup155
Name: nucleoporin 155
Synonyms: D930027M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 170762
VEGA: 15
HGNC: HGNC:8063
Homologene: 43155
Gria4
Name: glutamate receptor, ionotropic, AMPA4 (alpha 4)
Synonyms: Gluralpha4, Glur4, spkw1, Glur-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 14802
HGNC: HGNC:4574
Homologene: 20227
Kcnj1
Name: potassium inwardly-rectifying channel, subfamily J, member 1
Synonyms: ROMK, ROMK-2, Kir1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 56379
VEGA: 9
HGNC: HGNC:6255
Homologene: 56764
Senp2
Name: SUMO/sentrin specific peptidase 2
Synonyms: 2310007L05Rik, 4930538C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 75826
VEGA: 16
Homologene: 11005
Exoc5
Name: exocyst complex component 5
Synonyms: SEC10, Sec10l1, PRO1912
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105504
Homologene: 38195
Ago1
Name: argonaute RISC catalytic subunit 1
Synonyms: argonaute 1, Eif2c1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 236511
HGNC: HGNC:3262
Homologene: 81826
Eif4enif1
Name: eukaryotic translation initiation factor 4E nuclear import factor 1
Synonyms: A930019J01Rik, D11Ertd166e, Clast4, 2610509L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 74203
Homologene: 10522
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F32S1, jdf2, D7H15F37S1, rjs, D15F32S1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Rsf1
Name: remodeling and spacing factor 1
Synonyms: XAP8, p325, 4832420A03Rik, C030033M12Rik, Hbxap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233532
Homologene: 41142
Atp6v1a
Name: ATPase, H+ transporting, lysosomal V1 subunit A
Synonyms: Atp6a1, VA68, VPP2, lysosomal 70kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 11964
HGNC: HGNC:851
Homologene: 123934
Ehmt2
Name: euchromatic histone lysine N-methyltransferase 2
Synonyms: G9a, NG36, D17Ertd710e, Bat8, KMT1C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 110147
Homologene: 48460
Snx29
Name: sorting nexin 29
Synonyms: 4933437K13Rik, LOC385605, Rundc2a, LOC381035, Gm11170
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 74478
Homologene: 32706
Ttc23
Name: tetratricopeptide repeat domain 23
Synonyms: 1600012K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67009
Homologene: 11289
Tpcn2
Name: two pore segment channel 2
Synonyms: D830047E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233979
Homologene: 16375
Pou4f2
Name: POU domain, class 4, transcription factor 2
Synonyms: Brn-3b, Pou4f-rs1, Brn3b, mBrn3-3R, Brn-3.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 18997
HGNC: HGNC:9219
Homologene: 20959
Barx2
Name: BarH-like homeobox 2
Synonyms: 2310006E12Rik, Barx2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12023
HGNC: HGNC:956
Homologene: 2715
Ano4
Name: anoctamin 4
Synonyms: A330096O15Rik, Tmem16d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 320091
Homologene: 66599
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: Fam38b, Piezo2, 9030411M15Rik, Fam38b2, 9430028L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 667742
Homologene: 49695
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: 2900022L05Rik, Dnahc2, D330014H01Rik, Dnhd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Ttll7
Name: tubulin tyrosine ligase-like family, member 7
Synonyms: 1110049N09Rik, 4921517B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 70892
Homologene: 41578
F5
Name: coagulation factor V
Synonyms: Cf5, Cf-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 545030
Homologene: 83473
Pdzd8
Name: PDZ domain containing 8
Synonyms: Pdzk8, A630041P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107368
VEGA: 19
Homologene: 14879
Megf10
Name: multiple EGF-like-domains 10
Synonyms: LOC240312, 3000002B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 70417
Homologene: 23771
Hc
Name: hemolytic complement
Synonyms: C5, C5a, Hfib2, He
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Stard9
Name: START domain containing 9
Synonyms: E230025N21Rik, 4831403C07Rik, Kif16a, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 668880
Homologene: 130712
Abi3
Name: ABI gene family, member 3
Synonyms: 2210414K06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66610
Homologene: 9505
Alpk3
Name: alpha-kinase 3
Synonyms: Midori
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 116904
Homologene: 10813
Olfr930
Name: olfactory receptor 930
Synonyms: MOR171-46, GA_x6K02T2PVTD-32626123-32627049
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258269
VEGA: 9
Homologene: 138304
Olfr1277
Name: olfactory receptor 1277
Synonyms: GA_x6K02T2Q125-72321818-72320907, MOR248-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258391
Homologene: 105176
Ugt3a1
Name: UDP glycosyltransferases 3 family, polypeptide A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105887
Homologene: 122787
Krt87
Name: keratin 87
Synonyms: Krt83, Krt2-25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 406219
VEGA: 15
Homologene: 133804
Simc1
Name: SUMO-interacting motifs containing 1
Synonyms: 4732471D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 319719
Homologene: 131217
Stat6
Name: signal transducer and activator of transcription 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 20852
Homologene: 2373
Vmn2r-ps129
Name: vomeronasal 2, receptor, pseudogene 129
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 665976
Plag1
Name: pleiomorphic adenoma gene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56711
HGNC: HGNC:9045
Homologene: 1993
Olfr701
Name: olfactory receptor 701
Synonyms: 4932441H21Rik, GA_x6K02T2PBJ9-9195805-9196755, MOR283-1, 4933433E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 66786
Homologene: 12558
Skint8
Name: selection and upkeep of intraepithelial T cells 8
Synonyms: OTTMUSG00000009475
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 639774
Homologene: 106613
Vmn1r70
Name: vomeronasal 1 receptor 70
Synonyms: V1rl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 171262
Homologene: 74361
Zfp780b
Name: zinc finger protein 780B
Synonyms: B230208L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 338354
Homologene: 85969
Sh3rf3
Name: SH3 domain containing ring finger 3
Synonyms: Sh3md4, 4831416G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237353
Homologene: 77551
Pik3c2b
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
Synonyms: PI3K-C2beta, C330011J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240752
HGNC: HGNC:8972
Homologene: 20582
Hist1h2bl
Name: histone cluster 1, H2bl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 319185
HGNC: HGNC:4753
Homologene: 136773
Olfr559
Name: olfactory receptor 559
Synonyms: MOR11-1, GA_x6K02T2PBJ9-5441154-5440198
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259116
Homologene: 74124
Ttc29
Name: tetratricopeptide repeat domain 29
Synonyms: 1700031F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 73301
Homologene: 12918
Cabp5
Name: calcium binding protein 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 29865
Homologene: 8486
Scd4
Name: stearoyl-coenzyme A desaturase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 329065
Homologene: 77322
Col10a1
Name: collagen, type X, alpha 1
Synonyms: Col10, Col10a-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 12813
HGNC: HGNC:2185
Homologene: 55466
Slc26a1
Name: solute carrier family 26 (sulfate transporter), member 1
Synonyms: Sat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231583
Homologene: 32539
Gm8444
Name: predicted gene 8444
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 667073
VEGA: 15
Hp
Name: haptoglobin
Synonyms: preHP2, HP-1, zonulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 15439
HGNC: HGNC:5141
Homologene: 121756
Olfr1288
Name: olfactory receptor 1288
Synonyms: MOR245-9, GA_x6K02T2Q125-72530279-72531217
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258395
Homologene: 88360
Ifna15
Name: interferon alpha 15
Synonyms: Ifnaa, Gm12597
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242517
HGNC: HGNC:5425
Homologene: 68536
Erv3
Name: endogenous retroviral sequence 3
Synonyms: 1600014E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71995
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 133,090,713 bp
  • A to T, chromosome 1 at 164,184,996 bp
  • T to C, chromosome 2 at 35,039,684 bp
  • C to T, chromosome 2 at 111,269,612 bp
  • T to C, chromosome 2 at 111,478,988 bp
  • C to T, chromosome 2 at 120,700,075 bp
  • G to A, chromosome 2 at 131,856,005 bp
  • A to G, chromosome 3 at 146,940,162 bp
  • T to C, chromosome 4 at 3,904,618 bp
  • T to G, chromosome 4 at 88,558,073 bp
  • C to A, chromosome 4 at 111,950,193 bp
  • C to T, chromosome 4 at 126,443,228 bp
  • T to A, chromosome 5 at 108,673,570 bp
  • C to T, chromosome 5 at 124,584,297 bp
  • A to G, chromosome 7 at 10,633,903 bp
  • A to T, chromosome 7 at 13,401,335 bp
  • A to G, chromosome 7 at 27,963,568 bp
  • A to G, chromosome 7 at 56,068,053 bp
  • A to G, chromosome 7 at 67,711,366 bp
  • G to A, chromosome 7 at 81,093,257 bp
  • G to GACGGCGGCT, chromosome 7 at 97,579,909 bp
  • T to A, chromosome 7 at 102,724,485 bp
  • A to T, chromosome 7 at 106,818,460 bp
  • T to C, chromosome 7 at 145,268,869 bp
  • A to G, chromosome 8 at 78,325,576 bp
  • A to T, chromosome 8 at 78,435,474 bp
  • A to G, chromosome 8 at 109,576,774 bp
  • T to A, chromosome 9 at 4,537,646 bp
  • A to T, chromosome 9 at 31,913,008 bp
  • A to T, chromosome 9 at 32,397,125 bp
  • A to G, chromosome 9 at 38,930,920 bp
  • A to G, chromosome 10 at 34,395,282 bp
  • G to A, chromosome 10 at 58,813,984 bp
  • A to G, chromosome 10 at 88,982,265 bp
  • A to G, chromosome 10 at 127,655,444 bp
  • T to C, chromosome 11 at 3,239,420 bp
  • C to T, chromosome 11 at 69,458,920 bp
  • T to C, chromosome 11 at 95,832,858 bp
  • A to T, chromosome 13 at 21,715,978 bp
  • C to T, chromosome 13 at 54,524,621 bp
  • G to T, chromosome 14 at 33,146,990 bp
  • T to C, chromosome 14 at 49,014,322 bp
  • A to G, chromosome 15 at 8,128,411 bp
  • A to T, chromosome 15 at 9,306,086 bp
  • G to T, chromosome 15 at 81,843,593 bp
  • A to C, chromosome 15 at 101,487,531 bp
  • A to G, chromosome 16 at 11,738,437 bp
  • A to T, chromosome 16 at 22,028,558 bp
  • A to G, chromosome 16 at 44,098,831 bp
  • T to C, chromosome 17 at 22,995,172 bp
  • C to T, chromosome 17 at 34,899,091 bp
  • A to G, chromosome 18 at 57,242,727 bp
  • G to A, chromosome 18 at 63,114,948 bp
  • G to A, chromosome 19 at 44,344,792 bp
  • G to A, chromosome 19 at 59,305,209 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6036 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043257-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.