Strain Name:
C57BL/6J-MtgxR5636Btlr
Stock Number:
043287-MU
Citation ID:
RRID:MMRRC_043287-MU
Other Names:
R5636 (G1)
Major Collection:

Gene Information

Ubr5
Name: ubiquitin protein ligase E3 component n-recognin 5
Synonyms: 4432411E13Rik, Edd1, Edd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 70790
VEGA: 15
Homologene: 9295
Arpp19
Name: cAMP-regulated phosphoprotein 19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 59046
Homologene: 21318
Hcrtr1
Name: hypocretin (orexin) receptor 1
Synonyms: OX1R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230777
HGNC: HGNC:4848
Homologene: 37492
Bysl
Name: bystin-like
Synonyms: Enp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 53414
VEGA: 17
HGNC: HGNC:1157
Homologene: 2991
Sf3b1
Name: splicing factor 3b, subunit 1
Synonyms: SF3b155, 2810001M05Rik, Prp10, Targ4, SAP155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 81898
Homologene: 6696
Stam
Name: signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
Synonyms: STAM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20844
Homologene: 37788
Bms1
Name: BMS1, ribosome biogenesis factor
Synonyms: Bms1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 213895
Homologene: 7065
Akap13
Name: A kinase (PRKA) anchor protein 13
Synonyms: 1700026G02Rik, 5830460E08Rik, 5730522G15Rik, AKAP-Lbc, PROTO-LBC, PROTO-LB, Ht31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 75547
HGNC: HGNC:371
Homologene: 4903
Fbxo38
Name: F-box protein 38
Synonyms: 6030410I24Rik, SP329
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 107035
VEGA: 18
Homologene: 34526
Myo1b
Name: myosin IB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17912
HGNC: HGNC:7596
Homologene: 7856
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, D4Abb1e, 4833432B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100019
Homologene: 39689
Abcg2
Name: ATP binding cassette subfamily G member 2 (Junior blood group)
Synonyms: Bcrp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 26357
HGNC: HGNC:74
Homologene: 55852
Islr2
Name: immunoglobulin superfamily containing leucine-rich repeat 2
Synonyms: Linx, mbu-3, B930052A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 320563
VEGA: 9
Homologene: 10833
Spag9
Name: sperm associated antigen 9
Synonyms: 3110018C07Rik, JIP4, 4831406C20Rik, Mapk8ip4, JLP, syd1, 4733401I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 70834
Homologene: 2954
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329252
Homologene: 49680
Mon1a
Name: MON1 homolog A, secretory traffciking associated
Synonyms: 2810468K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 72825
Homologene: 7191
Ric3
Name: RIC3 acetylcholine receptor chaperone
Synonyms: E130307J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 320360
Homologene: 49772
Cdkl2
Name: cyclin-dependent kinase-like 2 (CDC2-related kinase)
Synonyms: Kkm, KKIAMRE, 5330436L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 53886
HGNC: HGNC:1782
Homologene: 55793
Fat2
Name: FAT atypical cadherin 2
Synonyms: Fath2, mKIAA0811, LOC245827, EMI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Slc4a3
Name: solute carrier family 4 (anion exchanger), member 3
Synonyms: A930038D23Rik, Ae3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20536
Homologene: 129474
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 672511
Homologene: 45439
Sptbn5
Name: spectrin beta, non-erythrocytic 5
Synonyms: Spnb5, EG640524
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 640524
Homologene: 41150
Scap
Name: SREBF chaperone
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235623
Homologene: 8160
Nlrp12
Name: NLR family, pyrin domain containing 12
Synonyms: Nalp12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 378425
Homologene: 16972
Vmn2r78
Name: vomeronasal 2, receptor 78
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 637896
Homologene: 115466
Capn1
Name: calpain 1
Synonyms: Capa1, Capa-1, mu-calpin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 12333
VEGA: 19
HGNC: HGNC:1476
Homologene: 3800
Pnp2
Name: purine-nucleoside phosphorylase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 667034
HGNC: HGNC:7892
Homologene: 227
Traf6
Name: TNF receptor-associated factor 6
Synonyms: C630032O20Rik, 2310003F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22034
Homologene: 3395
Hivep1
Name: human immunodeficiency virus type I enhancer binding protein 1
Synonyms: Cryabp1, alphaA-CRYBP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 110521
VEGA: 13
HGNC: HGNC:4920
Homologene: 1596
Rufy2
Name: RUN and FYVE domain-containing 2
Synonyms: 2610111M19Rik, LZ-FYVE, Denn, ZFYVE13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70432
Homologene: 23064
Pik3ca
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Synonyms: p110alpha, 6330412C24Rik, caPI3K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18706
HGNC: HGNC:8975
Homologene: 21249
Lrrc6
Name: leucine rich repeat containing 6 (testis)
Synonyms: LRTP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 54562
Homologene: 34534
Nos1ap
Name: nitric oxide synthase 1 (neuronal) adaptor protein
Synonyms: 6330408P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 70729
Homologene: 135990
Nuggc
Name: nuclear GTPase, germinal center associated
Synonyms: SLIP-GC, LOC239151, Gm600
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 100503545
Homologene: 72641
Abca5
Name: ATP-binding cassette, sub-family A (ABC1), member 5
Synonyms: ABC13, B930033A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217265
HGNC: HGNC:35
Homologene: 10263
Serpinb3c
Name: serine (or cysteine) peptidase inhibitor, clade B, member 3C
Synonyms: 1110001H02Rik, Serpinb4, 1110013A16Rik, ovalbumin, Scca2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381286
Homologene: 131278
Olfr1501
Name: olfactory receptor 1501
Synonyms: MOR212-3, GA_x6K02T2RE5P-4171358-4170411
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258626
Homologene: 64899
Atp6v0b
Name: ATPase, H+ transporting, lysosomal V0 subunit B
Synonyms: Atp6f, 2310024H13Rik, VMA16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 114143
HGNC: HGNC:861
Homologene: 2986
Smtn
Name: smoothelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 29856
Homologene: 8482
A1cf
Name: APOBEC1 complementation factor
Synonyms: ACF, apobec-1 complementation factor, 1810073H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 69865
VEGA: 19
Homologene: 16363
Skint8
Name: selection and upkeep of intraepithelial T cells 8
Synonyms: OTTMUSG00000009475
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 639774
Homologene: 106613
Accsl
Name: 1-aminocyclopropane-1-carboxylate synthase (non-functional)-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381411
Homologene: 86007
Gpd1
Name: glycerol-3-phosphate dehydrogenase 1 (soluble)
Synonyms: Gdc1, Gdc-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14555
HGNC: HGNC:4455
Homologene: 5593
Acvr2b
Name: activin receptor IIB
Synonyms: ActRIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 11481
VEGA: 9
HGNC: HGNC:174
Homologene: 863
Cyp2c38
Name: cytochrome P450, family 2, subfamily c, polypeptide 38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 13097
HGNC: HGNC:2622
Homologene: 117948
Mrgprb4
Name: MAS-related GPR, member B4
Synonyms: MrgB4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233230
Homologene: 115575
Atp10d
Name: ATPase, class V, type 10D
Synonyms: D5Buc24e, 9830145H18Rik, IMAGE:1069176
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231287
Tmem215
Name: transmembrane protein 215
Synonyms: A930001M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 320500
Homologene: 27946
Olfr332
Name: olfactory receptor 332
Synonyms: GA_x6K02T2NKPP-926908-927915, MOR284-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 257932
Homologene: 74137
Tex35
Name: testis expressed 35
Synonyms: 1700057K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 73435
Homologene: 49980
Gm13889
Name: predicted gene 13889
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 620695
Homologene: 83963
Cypt12
Name: cysteine-rich perinuclear theca 12
Synonyms: 1700001F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 75439
Carkd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 51,797,528 bp
  • T to C, chromosome 1 at 54,997,193 bp
  • C to T, chromosome 1 at 75,554,216 bp
  • T to C, chromosome 1 at 107,275,014 bp
  • T to C, chromosome 1 at 134,987,078 bp
  • C to T, chromosome 1 at 157,100,224 bp
  • T to A, chromosome 1 at 170,349,399 bp
  • G to T, chromosome 2 at 14,117,427 bp
  • C to T, chromosome 2 at 93,869,025 bp
  • A to G, chromosome 2 at 93,956,686 bp
  • G to A, chromosome 2 at 101,696,909 bp
  • G to A, chromosome 2 at 120,057,404 bp
  • C to T, chromosome 3 at 17,948,585 bp
  • G to A, chromosome 3 at 32,461,560 bp
  • C to T, chromosome 4 at 32,695,480 bp
  • A to G, chromosome 4 at 40,474,394 bp
  • C to A, chromosome 4 at 111,950,193 bp
  • T to C, chromosome 4 at 117,886,385 bp
  • C to A, chromosome 4 at 130,130,945 bp
  • A to G, chromosome 5 at 72,288,219 bp
  • T to C, chromosome 5 at 92,033,742 bp
  • T to A, chromosome 6 at 58,672,056 bp
  • C to A, chromosome 6 at 118,388,825 bp
  • A to T, chromosome 7 at 3,225,294 bp
  • A to G, chromosome 7 at 48,198,470 bp
  • A to G, chromosome 7 at 75,704,372 bp
  • A to G, chromosome 7 at 86,954,429 bp
  • G to A, chromosome 7 at 109,038,820 bp
  • A to G, chromosome 8 at 11,502,676 bp
  • T to C, chromosome 9 at 58,201,301 bp
  • C to T, chromosome 9 at 75,037,933 bp
  • T to C, chromosome 9 at 107,901,240 bp
  • G to T, chromosome 9 at 110,380,594 bp
  • A to G, chromosome 9 at 119,428,309 bp
  • T to A, chromosome 10 at 62,997,954 bp
  • T to G, chromosome 11 at 3,517,829 bp
  • T to C, chromosome 11 at 55,282,481 bp
  • T to C, chromosome 11 at 58,490,051 bp
  • C to A, chromosome 11 at 94,069,012 bp
  • A to G, chromosome 11 at 110,301,536 bp
  • G to A, chromosome 11 at 119,436,629 bp
  • A to C, chromosome 11 at 119,436,905 bp
  • C to T, chromosome 13 at 42,163,456 bp
  • A to G, chromosome 14 at 50,956,192 bp
  • A to T, chromosome 14 at 65,648,188 bp
  • T to A, chromosome 15 at 37,983,996 bp
  • A to T, chromosome 15 at 66,500,816 bp
  • A to T, chromosome 15 at 99,722,058 bp
  • A to C, chromosome 17 at 47,602,723 bp
  • A to G, chromosome 18 at 62,511,018 bp
  • A to T, chromosome 19 at 6,014,442 bp
  • C to T, chromosome 19 at 13,838,337 bp
  • C to T, chromosome 19 at 31,944,982 bp
  • G to A, chromosome 19 at 39,438,306 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5636 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043287-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.