Strain Name:
C57BL/6J-MtgxR5639Btlr
Stock Number:
043288-MU
Citation ID:
RRID:MMRRC_043288-MU
Other Names:
R5639 (G1)
Major Collection:

Gene Information

Trmo
Name: tRNA methyltransferase O
Synonyms: 5830415F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74753
Homologene: 32316
Ccn1
Name: cellular communication network factor 1
Synonyms: CCN1, Cyr61
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 16007
HGNC: HGNC:2654
Homologene: 1194
Sptan1
Name: spectrin alpha, non-erythrocytic 1
Synonyms: alpha-fodrin, Spna-2, 2610027H02Rik, Spna2, alphaII-spectrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20740
Homologene: 2353
Drd5
Name: dopamine receptor D5
Synonyms: DRD1b, Drd-5, Gpcr1, Drd1b, D5R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13492
HGNC: HGNC:3026
Homologene: 20216
Armc8
Name: armadillo repeat containing 8
Synonyms: HSPC056, 1200015K23Rik, Gid5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74125
Homologene: 9121
Epc2
Name: enhancer of polycomb homolog 2
Synonyms: D2Ertd694e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227867
Homologene: 32274
Tep1
Name: telomerase associated protein 1
Synonyms: Tp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21745
VEGA: 14
Homologene: 5157
Oga
Name: O-GlcNAcase
Synonyms: Hy5, 5830447M11Rik, 4833427O07Rik, 2810009A20Rik, Mgea5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 76055
VEGA: 19
HGNC: HGNC:7056
Homologene: 8154
Bicc1
Name: BicC family RNA binding protein 1
Synonyms: Bic-C, jcpk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 83675
Homologene: 12856
Fndc3b
Name: fibronectin type III domain containing 3B
Synonyms: 1600019O04Rik, fad104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72007
Homologene: 11244
Aars
Name: alanyl-tRNA synthetase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234734
HGNC: HGNC:20
Homologene: 1213
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: A930005E13Rik, LOC381562, D930005K06Rik, 1810009A16Rik, Zubr1, p600
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69116
Homologene: 10804
Nrgn
Name: neurogranin
Synonyms: NG/RC3, NG, Pss1, 0710001B06Rik, RC3, protein kinase C substrate
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 64011
HGNC: HGNC:8000
Homologene: 136026
Lman1l
Name: lectin, mannose-binding 1 like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235416
HGNC: HGNC:6632
Homologene: 11047
Lsm14a
Name: LSM14A mRNA processing body assembly factor
Synonyms: 2700023B17Rik, Tral
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67070
Homologene: 40537
Ankrd26
Name: ankyrin repeat domain 26
Synonyms: 5730521P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232339
Homologene: 45968
Zbtb44
Name: zinc finger and BTB domain containing 44
Synonyms: 6030404E16Rik, Btbd15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235132
VEGA: 9
Homologene: 18221
Aldh1a1
Name: aldehyde dehydrogenase family 1, subfamily A1
Synonyms: ALDH1, E1, Ahd-2, Ahd2, Raldh1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 11668
HGNC: HGNC:402
Homologene: 110441
Krt74
Name: keratin 74
Synonyms: Kb37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 406222
VEGA: 15
Dmpk
Name: dystrophia myotonica-protein kinase
Synonyms: DM, Dm15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13400
HGNC: HGNC:2933
Homologene: 3247
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: CD91, A2mr, b2b1554Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Nlrp4a
Name: NLR family, pyrin domain containing 4A
Synonyms: Nalp-eta, E330028A19Rik, Nalp4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243880
Homologene: 79696
Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
Synonyms: Scy, Crsh, crash, Adgrc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12614
VEGA: 15
HGNC: HGNC:1850
Homologene: 7665
Vwa3a
Name: von Willebrand factor A domain containing 3A
Synonyms: E030013G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233813
Homologene: 18607
Farp1
Name: FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
Synonyms: Cdep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 223254
HGNC: HGNC:3591
Homologene: 38098
Unc79
Name: unc-79 homolog
Synonyms: 9030205A07Rik, Mlca3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217843
Homologene: 41397
Lipe
Name: lipase, hormone sensitive
Synonyms: HSL, 4933403G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16890
HGNC: HGNC:6621
Homologene: 3912
Pign
Name: phosphatidylinositol glycan anchor biosynthesis, class N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 27392
HGNC: HGNC:8967
Homologene: 6330
Spag17
Name: sperm associated antigen 17
Synonyms: 4931427F14Rik, PF6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74362
Homologene: 52601
Gp6
Name: glycoprotein 6 (platelet)
Synonyms: Gpvi, 9830166G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243816
Homologene: 9488
Mctp1
Name: multiple C2 domains, transmembrane 1
Synonyms: 2810465F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 78771
Homologene: 75211
Clpx
Name: caseinolytic mitochondrial matrix peptidase chaperone subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270166
HGNC: HGNC:2088
Homologene: 4851
Fam186a
Name: family with sequence similarity 186, member A
Synonyms: LOC380973, 1700030F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72277
Srrm4
Name: serine/arginine repetitive matrix 4
Synonyms: fp, flopsy, B230202K19Rik, nSR100, 1500001A10Rik, bv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68955
Homologene: 49869
Skint8
Name: selection and upkeep of intraepithelial T cells 8
Synonyms: OTTMUSG00000009475
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 639774
Homologene: 106613
Olfr370
Name: olfactory receptor 370
Synonyms: GA_x6K02T2NUPS-11609807-11610751, MOR267-16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 258267
Homologene: 74037
Ercc3
Name: excision repair cross-complementing rodent repair deficiency, complementation group 3
Synonyms: XPB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13872
HGNC: HGNC:3435
Homologene: 96
Gpc5
Name: glypican 5
Synonyms: A230034F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 103978
HGNC: HGNC:4453
Homologene: 3285
Zfp709
Name: zinc finger protein 709
Synonyms: GIOT-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 236193
Homologene: 136795
Kcnq3
Name: potassium voltage-gated channel, subfamily Q, member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110862
HGNC: HGNC:6297
Homologene: 20949
Tas1r2
Name: taste receptor, type 1, member 2
Synonyms: TR2, T1r2, Gpr71
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 83770
Homologene: 75323
Vmn2r12
Name: vomeronasal 2, receptor 12
Synonyms: Gm6769
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 627569
Homologene: 129606
Olfr1246
Name: olfactory receptor 1246
Synonyms: GA_x6K02T2Q125-51034790-51033846, MOR231-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258788
Homologene: 74246
Gm11595
Name: predicted gene 11595
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 100040276
Homologene: 124486
Samm50
Name: SAMM50 sorting and assembly machinery component
Synonyms: 1110030L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68653
VEGA: 15
Homologene: 41034
Trmu
Name: tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
Synonyms: 1600025P05Rik, 1110005N20Rik, Trmt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72026
Homologene: 5589
Zfp663
Name: zinc finger protein 663
Synonyms: LOC381405, Gm1008
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381405
Homologene: 128277
Zdhhc3
Name: zinc finger, DHHC domain containing 3
Synonyms: 1810006O10Rik, Zfp373, 1110020O22Rik, GODZ, 2210017C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69035
Homologene: 9582
Dnah7c
Name: dynein, axonemal, heavy chain 7C
Synonyms: Dnahc7c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100101919
Homologene: 41287
Sesn1
Name: sestrin 1
Synonyms: 1110002G11Rik, SEST1, PA26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 140742
Homologene: 8697
Olfr564
Name: olfactory receptor 564
Synonyms: GA_x6K02T2PBJ9-5513635-5514627, MOR14-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258356
Homologene: 121507
Car11
Name: carbonic anhydrase 11
Synonyms: CA-RP XI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12348
HGNC: HGNC:1370
Homologene: 36061
Zfp189
Name: zinc finger protein 189
Synonyms: C430015I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230162
Homologene: 20737
Yif1a
Name: Yip1 interacting factor homolog A (S. cerevisiae)
Synonyms: 5330422J23Rik, Yif1p, 54TM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 68090
VEGA: 19
Homologene: 56295
Pdia6
Name: protein disulfide isomerase associated 6
Synonyms: CaBP5, P5, 1700015E05Rik, Txndc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 71853
Homologene: 4198
Plscr5
Name: phospholipid scramblase family, member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100504689
Homologene: 28688
Mfsd7c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to G, chromosome 1 at 46,739,668 bp
  • T to A, chromosome 1 at 105,589,315 bp
  • C to T, chromosome 2 at 29,990,993 bp
  • A to G, chromosome 2 at 49,451,891 bp
  • T to C, chromosome 2 at 89,590,725 bp
  • T to C, chromosome 2 at 165,353,009 bp
  • C to T, chromosome 3 at 27,426,153 bp
  • G to T, chromosome 3 at 100,056,166 bp
  • A to C, chromosome 3 at 145,648,697 bp
  • T to C, chromosome 4 at 46,382,073 bp
  • T to A, chromosome 4 at 49,530,153 bp
  • C to A, chromosome 4 at 111,950,193 bp
  • A to G, chromosome 4 at 139,452,648 bp
  • A to T, chromosome 4 at 139,659,796 bp
  • T to A, chromosome 5 at 38,319,835 bp
  • G to A, chromosome 5 at 109,092,800 bp
  • T to A, chromosome 5 at 116,591,359 bp
  • T to C, chromosome 6 at 118,539,724 bp
  • C to A, chromosome 7 at 4,394,131 bp
  • A to G, chromosome 7 at 19,092,600 bp
  • T to C, chromosome 7 at 25,383,325 bp
  • G to A, chromosome 7 at 26,457,030 bp
  • T to C, chromosome 7 at 34,353,510 bp
  • T to A, chromosome 7 at 45,702,621 bp
  • A to G, chromosome 7 at 102,803,993 bp
  • A to C, chromosome 7 at 120,790,143 bp
  • T to G, chromosome 8 at 71,889,991 bp
  • T to C, chromosome 8 at 83,541,344 bp
  • T to C, chromosome 8 at 111,043,234 bp
  • A to T, chromosome 9 at 31,054,052 bp
  • T to C, chromosome 9 at 37,546,048 bp
  • A to T, chromosome 9 at 57,611,866 bp
  • T to A, chromosome 9 at 65,329,830 bp
  • A to T, chromosome 9 at 92,205,511 bp
  • A to G, chromosome 9 at 99,496,149 bp
  • T to C, chromosome 9 at 123,100,345 bp
  • A to G, chromosome 10 at 41,811,271 bp
  • A to T, chromosome 10 at 70,940,520 bp
  • A to G, chromosome 10 at 127,593,839 bp
  • G to A, chromosome 11 at 99,772,555 bp
  • A to G, chromosome 12 at 17,278,593 bp
  • A to T, chromosome 12 at 85,747,476 bp
  • A to C, chromosome 12 at 103,171,572 bp
  • T to C, chromosome 13 at 77,024,783 bp
  • A to G, chromosome 14 at 50,853,605 bp
  • T to C, chromosome 14 at 115,092,747 bp
  • T to A, chromosome 14 at 121,275,382 bp
  • T to A, chromosome 15 at 65,997,750 bp
  • T to G, chromosome 15 at 84,214,128 bp
  • T to A, chromosome 15 at 85,882,698 bp
  • C to G, chromosome 15 at 86,030,767 bp
  • T to C, chromosome 15 at 99,947,050 bp
  • T to G, chromosome 15 at 101,756,760 bp
  • T to C, chromosome 18 at 32,265,714 bp
  • T to C, chromosome 19 at 5,088,750 bp
  • C to A, chromosome 19 at 20,623,422 bp
  • A to G, chromosome 19 at 45,776,999 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5639 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043288-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.