Strain Name:
C57BL/6J-MtgxR5646Btlr
Stock Number:
043294-MU
Citation ID:
RRID:MMRRC_043294-MU
Other Names:
R5646 (G1)
Major Collection:

Gene Information

Mitf
Name: melanogenesis associated transcription factor
Synonyms: BCC2, Gsfbcc2, wh, bHLHe32, mi
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 17342
HGNC: HGNC:7105
Homologene: 4892
Drd2
Name: dopamine receptor D2
Synonyms: D2R, Drd-2, D2 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 13489
VEGA: 9
HGNC: HGNC:3023
Homologene: 22561
Gfap
Name: glial fibrillary acidic protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14580
HGNC: HGNC:4235
Homologene: 1554
Add1
Name: adducin 1 (alpha)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 11518
HGNC: HGNC:243
Homologene: 22758
Thbs3
Name: thrombospondin 3
Synonyms: TSP3, Thbs-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 21827
Homologene: 5159
Pik3c2a
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Synonyms: PI3KC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18704
HGNC: HGNC:8971
Homologene: 20581
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105689
Homologene: 9005
Ttc39b
Name: tetratricopeptide repeat domain 39B
Synonyms: 1810054D07Rik, 9130422G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 69863
Homologene: 25228
Usp25
Name: ubiquitin specific peptidase 25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 30940
VEGA: 16
Homologene: 8374
Pde7a
Name: phosphodiesterase 7A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18583
HGNC: HGNC:8791
Homologene: 1956
Ergic1
Name: endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
Synonyms: 1200007D18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 67458
Homologene: 41667
Smg1
Name: SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
Synonyms: 5430435M13Rik, C130002K18Rik, 2610207I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233789
Homologene: 56697
Dmtf1
Name: cyclin D binding myb-like transcription factor 1
Synonyms: Dmp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 23857
Homologene: 8017
Vps26a
Name: VPS26 retromer complex component A
Synonyms: H beta 58, Vps26, HB58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 30930
VEGA: 10
Homologene: 68420
Pex14
Name: peroxisomal biogenesis factor 14
Synonyms: Pex14p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56273
HGNC: HGNC:8856
Homologene: 37936
Hip1
Name: huntingtin interacting protein 1
Synonyms: A930014B11Rik, HIP-1, 2610109B09Rik, E130315I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 215114
HGNC: HGNC:4913
Homologene: 68463
Robo2
Name: roundabout guidance receptor 2
Synonyms: 2600013A04Rik, 9430089E08Rik, D230004I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 268902
Homologene: 43188
Bbs9
Name: Bardet-Biedl syndrome 9 (human)
Synonyms: EST 3159894, E130103I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319845
Homologene: 44480
Zfp600
Name: zinc finger protein 600
Synonyms: Gm13164
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 667666
Homologene: 133076
Gfpt1
Name: glutamine fructose-6-phosphate transaminase 1
Synonyms: 2810423A18Rik, GFAT, GFA, GFAT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14583
HGNC: HGNC:4241
Homologene: 68220
Cdh9
Name: cadherin 9
Synonyms: T1-cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12565
HGNC: HGNC:1768
Homologene: 9450
Timp2
Name: tissue inhibitor of metalloproteinase 2
Synonyms: D11Bwg1104e, TIMP-2, Timp-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 21858
Homologene: 2444
Sptb
Name: spectrin beta, erythrocytic
Synonyms: spectrin R, brain erythroid spectrin (235E), LOC383567, Spnb-1, Spnb1, D330027P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20741
Homologene: 295
Agap3
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Synonyms: MRIP-1, Centg3, Crag
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 213990
Homologene: 23742
Zswim4
Name: zinc finger SWIM-type containing 4
Synonyms: E130119J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 212168
Homologene: 18183
Tmtc1
Name: transmembrane and tetratricopeptide repeat containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 387314
Homologene: 65299
H2-T23
Name: histocompatibility 2, T region locus 23
Synonyms: T18c, T23b, Qed-1, Qa1, Qa-1, 37b, H-2T23, T18c(37), T23d, 37c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 15040
HGNC: HGNC:4962
Homologene: 134018
Camk1
Name: calcium/calmodulin-dependent protein kinase I
Synonyms: D6Ertd263e, CaMKIalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 52163
HGNC: HGNC:1459
Homologene: 117458
Cdc42bpa
Name: CDC42 binding protein kinase alpha
Synonyms: A930014J19Rik, DMPK-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226751
HGNC: HGNC:1737
Homologene: 55765
Zmiz2
Name: zinc finger, MIZ-type containing 2
Synonyms: 2410117E06Rik, D11Bwg0280e, Zimp7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 52915
Homologene: 18000
Mmp9
Name: matrix metallopeptidase 9
Synonyms: Gel B, MMP-9, Clg4b, B/MMP9, Gelatinase B, gelatinase B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17395
HGNC: HGNC:7176
Homologene: 3659
Zbtb41
Name: zinc finger and BTB domain containing 41
Synonyms: 8430415N23Rik, 9830132G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226470
Homologene: 27795
Sec24c
Name: Sec24 related gene family, member C (S. cerevisiae)
Synonyms: 2610204K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 218811
VEGA: 14
Homologene: 3615
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: A530024P18Rik, myomaxin, Cmya3, 2310008C07Rik, mXin beta, 2310003D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241431
Homologene: 19388
Slc15a3
Name: solute carrier family 15, member 3
Synonyms: cI-1, Ci1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 65221
Homologene: 69222
Olfr432
Name: olfactory receptor 432
Synonyms: GA_x6K02T2P20D-21124681-21123743, MOR123-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 258711
Homologene: 81532
Sptbn5
Name: spectrin beta, non-erythrocytic 5
Synonyms: Spnb5, EG640524
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 640524
Homologene: 41150
Cass4
Name: Cas scaffolding protein family member 4
Synonyms: F730031O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 320664
Homologene: 75128
Myh2
Name: myosin, heavy polypeptide 2, skeletal muscle, adult
Synonyms: Myhsf1, Myhs-f1, MyHC-IIa, MHC2A, Myhs-f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17882
HGNC: HGNC:7572
Homologene: 23019
Olfr771
Name: olfactory receptor 771
Synonyms: MOR114-8, GA_x6K02T2PULF-10846420-10845467
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258540
Homologene: 74047
Prkcg
Name: protein kinase C, gamma
Synonyms: Pkcc, PKCgamma, Prkcc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18752
HGNC: HGNC:9402
Homologene: 20602
Ccdc39
Name: coiled-coil domain containing 39
Synonyms: 4921507O14Rik, D3Ertd789e, b2b1735Clo, b2b1304Clo, b2b2025.1Clo, prh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 51938
Homologene: 12149
Arhgef11
Name: Rho guanine nucleotide exchange factor (GEF) 11
Synonyms: PDZ-RhoGEF, Prg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 213498
Homologene: 11409
Atp2a1
Name: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Synonyms: SERCA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11937
HGNC: HGNC:811
Homologene: 7635
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Fmnl1
Name: formin-like 1
Synonyms: formin-related gene in leukocytes, 8030453N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 57778
HGNC: HGNC:1212
Homologene: 135620
Myo3b
Name: myosin IIIB
Synonyms: A430065P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 329421
Homologene: 51393
Col4a2
Name: collagen, type IV, alpha 2
Synonyms: Col4a-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12827
HGNC: HGNC:2203
Homologene: 1390
Pfkfb4
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270198
HGNC: HGNC:8875
Homologene: 48288
4932415D10Rik
Name: RIKEN cDNA 4932415D10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 102635990
VEGA: 10
Homologene: 82476
Rims4
Name: regulating synaptic membrane exocytosis 4
Synonyms: Rim4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241770
Homologene: 18123
Olfr447
Name: olfactory receptor 447
Synonyms: MOR261-1, GA_x6K02T2P3E9-4647978-4647046
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 258990
Homologene: 17457
Dlg5
Name: discs large MAGUK scaffold protein 5
Synonyms: 4933429D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 71228
HGNC: HGNC:2904
Homologene: 3486
Cdcp2
Name: CUB domain containing protein 2
Synonyms: D030010E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242603
Homologene: 138406
Kif19a
Name: kinesin family member 19A
Synonyms: N-8 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 286942
Homologene: 17709
Prob1
Name: proline rich basic protein 1
Synonyms: LOC381148, Gm1614
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 381148
Homologene: 83773
Olfr202
Name: olfactory receptor 202
Synonyms: GA_x54KRFPKG5P-55498766-55497843, MOR182-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258997
Homologene: 138323
Vill
Name: villin-like
Synonyms: Villp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22351
Homologene: 22650
Meioc
Name: meiosis specific with coiled-coil domain
Synonyms: LOC380729, Gm1564, LOC268491
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268491
Homologene: 19559
Zfp438
Name: zinc finger protein 438
Synonyms: 9430091M14Rik, B830013J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240186
VEGA: 18
Homologene: 18695
Cyp2d9
Name: cytochrome P450, family 2, subfamily d, polypeptide 9
Synonyms: Cyp2d, testosterone 16alpha-hydroxylase, P450-2D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 13105
VEGA: 15
Homologene: 86099
Vmn2r76
Name: vomeronasal 2, receptor 76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 675969
Homologene: 104330
Lin7b
Name: lin-7 homolog B (C. elegans)
Synonyms: Veli2, MALS-2, LIN-7B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22342
Homologene: 22648
Zfp84
Name: zinc finger protein 84
Synonyms: Zfp69, KRAB18, 4633401C23Rik, 2210410P13Rik, C86188
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74352
Homologene: 51858
Vmn1r65
Name: vomeronasal 1 receptor 65
Synonyms: V1rd6, V3R6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 81013
Homologene: 110799
Foxd2
Name: forkhead box D2
Synonyms: Mf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 17301
HGNC: HGNC:3803
Homologene: 3292
Syt12
Name: synaptotagmin XII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 171180
Homologene: 15895
Mettl5
Name: methyltransferase like 5
Synonyms: 2810410A08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75422
Homologene: 8570
Olfr1317
Name: olfactory receptor 1317
Synonyms: MOR245-4, GA_x6K02T2Q125-73188162-73189112
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258440
Homologene: 71983
Nde1
Name: nudE neurodevelopment protein 1
Synonyms: mNudE, 2810027M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 67203
Homologene: 32354
Tas2r107
Name: taste receptor, type 2, member 107
Synonyms: mGR06, T2R4, STC 5-1, T2R07, mt2r43, Tas2r7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 387342
Homologene: 137369
Olfr550
Name: olfactory receptor 550
Synonyms: MOR16-1, GA_x6K02T2PBJ9-5297243-5298193
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259108
Homologene: 17507
Ttc6
Name: tetratricopeptide repeat domain 6
Synonyms: Gm9813, EG639426, LOC217602, 4921506M07Rik, AU024163
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 70846
Homologene: 78002
Olfr753-ps1
Name: olfactory receptor 753, pseudogene 1
Synonyms: GA_x6K02T2PSCP-1611898-1610960, MOR256-38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258052
Tnni2
Name: troponin I, skeletal, fast 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 21953
Homologene: 37752
Pcdhga8
Name: protocadherin gamma subfamily A, 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93716
HGNC: HGNC:8706
Homologene: 57162
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 139,423,763 bp
  • C to T, chromosome 1 at 174,051,287 bp
  • A to G, chromosome 1 at 180,106,094 bp
  • T to C, chromosome 2 at 67,510,790 bp
  • C to A, chromosome 2 at 69,881,319 bp
  • T to C, chromosome 2 at 70,314,430 bp
  • T to C, chromosome 2 at 112,142,683 bp
  • A to T, chromosome 2 at 120,048,811 bp
  • C to T, chromosome 2 at 163,864,017 bp
  • T to A, chromosome 2 at 164,949,050 bp
  • T to G, chromosome 2 at 172,416,245 bp
  • A to T, chromosome 3 at 19,233,773 bp
  • A to T, chromosome 3 at 33,825,550 bp
  • T to C, chromosome 3 at 87,684,486 bp
  • T to C, chromosome 3 at 89,219,098 bp
  • G to A, chromosome 4 at 83,244,070 bp
  • T to C, chromosome 4 at 107,105,142 bp
  • C to T, chromosome 4 at 114,908,635 bp
  • T to C, chromosome 4 at 146,195,100 bp
  • T to C, chromosome 4 at 148,961,453 bp
  • G to A, chromosome 5 at 9,124,515 bp
  • C to A, chromosome 5 at 24,483,397 bp
  • C to A, chromosome 5 at 34,630,680 bp
  • G to A, chromosome 5 at 135,428,741 bp
  • A to G, chromosome 6 at 42,911,523 bp
  • A to G, chromosome 6 at 87,042,999 bp
  • A to T, chromosome 6 at 98,013,694 bp
  • A to G, chromosome 6 at 113,339,340 bp
  • A to G, chromosome 6 at 131,659,708 bp
  • G to A, chromosome 6 at 148,246,831 bp
  • T to A, chromosome 7 at 3,329,081 bp
  • T to A, chromosome 7 at 6,009,224 bp
  • C to T, chromosome 7 at 29,776,393 bp
  • T to C, chromosome 7 at 45,369,193 bp
  • C to A, chromosome 7 at 86,226,053 bp
  • A to C, chromosome 7 at 102,579,305 bp
  • C to A, chromosome 7 at 116,405,951 bp
  • A to T, chromosome 7 at 118,212,559 bp
  • A to G, chromosome 7 at 126,453,105 bp
  • A to T, chromosome 7 at 142,443,913 bp
  • G to A, chromosome 8 at 11,441,281 bp
  • A to T, chromosome 8 at 84,231,110 bp
  • T to C, chromosome 9 at 22,578,715 bp
  • A to G, chromosome 9 at 49,404,912 bp
  • A to T, chromosome 9 at 108,110,432 bp
  • A to T, chromosome 9 at 109,008,421 bp
  • A to T, chromosome 9 at 119,071,162 bp
  • A to C, chromosome 10 at 62,468,298 bp
  • A to G, chromosome 10 at 82,283,776 bp
  • T to C, chromosome 10 at 129,160,837 bp
  • T to A, chromosome 11 at 6,402,837 bp
  • A to T, chromosome 11 at 67,188,812 bp
  • T to A, chromosome 11 at 102,675,257 bp
  • T to C, chromosome 11 at 102,891,456 bp
  • A to G, chromosome 11 at 103,196,512 bp
  • A to C, chromosome 11 at 114,779,654 bp
  • A to T, chromosome 11 at 118,317,532 bp
  • A to T, chromosome 12 at 57,576,019 bp
  • G to T, chromosome 12 at 76,587,441 bp
  • C to A, chromosome 14 at 20,679,573 bp
  • T to A, chromosome 14 at 24,158,699 bp
  • T to A, chromosome 14 at 103,169,910 bp
  • G to A, chromosome 15 at 16,823,285 bp
  • A to G, chromosome 15 at 82,452,464 bp
  • T to C, chromosome 16 at 14,169,514 bp
  • C to T, chromosome 16 at 59,283,979 bp
  • T to C, chromosome 16 at 73,961,819 bp
  • G to A, chromosome 16 at 77,050,472 bp
  • T to C, chromosome 17 at 26,614,358 bp
  • C to G, chromosome 17 at 36,031,803 bp
  • T to C, chromosome 17 at 37,169,917 bp
  • T to C, chromosome 18 at 5,214,526 bp
  • A to T, chromosome 18 at 35,654,114 bp
  • A to G, chromosome 18 at 37,726,770 bp
  • A to T, chromosome 19 at 4,456,541 bp
  • A to G, chromosome 19 at 10,843,210 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5646 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043294-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.