Strain Name:
C57BL/6J-MtgxR5661Btlr
Stock Number:
043304-MU
Citation ID:
RRID:MMRRC_043304-MU
Other Names:
R5661 (G1)
Major Collection:

Gene Information

Myo5a
Name: myosin VA
Synonyms: MVa, MyoVA, Myo5, flail, 9630007J19Rik, Dbv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17918
HGNC: HGNC:7602
Homologene: 20100
Pax2
Name: paired box 2
Synonyms: Pax-2, Opdc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18504
HGNC: HGNC:8616
Homologene: 2968
Epha7
Name: Eph receptor A7
Synonyms: MDK1, Ebk, Cek11, Ehk3, Hek11, Mdk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13841
HGNC: HGNC:3390
Homologene: 20935
Kdm5b
Name: lysine (K)-specific demethylase 5B
Synonyms: PLU-1, 2010009J12Rik, Rb-Bp2, Plu1, 2210016I17Rik, D1Ertd202e, Jarid1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 75605
Homologene: 48448
Gli2
Name: GLI-Kruppel family member GLI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14633
HGNC: HGNC:4318
Homologene: 12725
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNA-PKcs, slip, DNAPDcs, DNA-PK, XRCC7, DOXNPH, dxnph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Ppp4r1
Name: protein phosphatase 4, regulatory subunit 1
Synonyms: Pp4r1, 3110001J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70351
HGNC: HGNC:9320
Homologene: 81737
Terf1
Name: telomeric repeat binding factor 1
Synonyms: Trf1, Trbf1, Pin2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21749
Homologene: 7570
Sec24d
Name: Sec24 related gene family, member D (S. cerevisiae)
Synonyms: 2310020L09Rik, LOC383951
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69608
Homologene: 40986
Sec16a
Name: SEC16 homolog A, endoplasmic reticulum export factor
Synonyms: C230052J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227648
Homologene: 10533
Tut4
Name: terminal uridylyl transferase 4
Synonyms: 6030404K05Rik, 9230115F04Rik, Tent3a, Zcchc11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230594
Homologene: 35279
Actn1
Name: actinin, alpha 1
Synonyms: 3110023F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 109711
VEGA: 12
HGNC: HGNC:163
Homologene: 55553
Ccdc80
Name: coiled-coil domain containing 80
Synonyms: Urb, Ssg1, 2610001E17Rik, DRO1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67896
Homologene: 12206
Trak1
Name: trafficking protein, kinesin binding 1
Synonyms: 2310001H13Rik, hyrt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67095
Homologene: 25103
Pi4k2b
Name: phosphatidylinositol 4-kinase type 2 beta
Synonyms: 4933409G22Rik, 2610042N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67073
Homologene: 32405
Kansl3
Name: KAT8 regulatory NSL complex subunit 3
Synonyms: 4632411B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226976
Homologene: 9949
Hjurp
Name: Holliday junction recognition protein
Synonyms: C330011F01Rik, A730008H23Rik, 6430706D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381280
Homologene: 10184
Hnrnph1
Name: heterogeneous nuclear ribonucleoprotein H1
Synonyms: E430005G16Rik, Hnrph1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 59013
HGNC: HGNC:5041
Homologene: 31318
Carm1
Name: coactivator-associated arginine methyltransferase 1
Synonyms: Prmt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 59035
Homologene: 10990
Brd3
Name: bromodomain containing 3
Synonyms: RINGL3, ORFX, 2410084F24Rik, Fsrg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67382
HGNC: HGNC:1104
Homologene: 81801
Mis18bp1
Name: MIS18 binding protein 1
Synonyms: C79407
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217653
Homologene: 10147
Retnlb
Name: resistin like beta
Synonyms: 9030012B21Rik, Relmb, Fizz2, Xcp3, RELMbeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 57263
VEGA: 16
Homologene: 10735
Pgk2
Name: phosphoglycerate kinase 2
Synonyms: Tcp-2, Pgk-2, Tcp-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18663
VEGA: 17
HGNC: HGNC:8898
Homologene: 57138
Zfpm2
Name: zinc finger protein, multitype 2
Synonyms: FOG-2, FOG2, B330005D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22762
VEGA: 15
Homologene: 8008
Mocos
Name: molybdenum cofactor sulfurase
Synonyms: 1110018O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68591
VEGA: 18
Homologene: 9931
Enpep
Name: glutamyl aminopeptidase
Synonyms: Bp-1/6C3, APA, Ly-51, Ly51, 6030431M22Rik, aminopeptidase-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 13809
HGNC: HGNC:3355
Homologene: 68216
Foxn4
Name: forkhead box N4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 116810
Homologene: 17526
Avl9
Name: AVL9 cell migration associated
Synonyms: D730049P16Rik, 5830411G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 78937
Homologene: 62425
Trappc11
Name: trafficking protein particle complex 11
Synonyms: D030016E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 320714
Homologene: 11076
Slc5a8
Name: solute carrier family 5 (iodide transporter), member 8
Synonyms: SMCT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216225
VEGA: 10
Homologene: 64832
Madd
Name: MAP-kinase activating death domain
Synonyms: 9630059K23Rik, Rab3 GEP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228355
HGNC: HGNC:6766
Homologene: 14249
Msto1
Name: misato 1, mitochondrial distribution and morphology regulator
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229524
Homologene: 41228
Plcb3
Name: phospholipase C, beta 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18797
VEGA: 19
HGNC: HGNC:9056
Homologene: 47960
Vmn1r170
Name: vomeronasal 1 receptor 170
Synonyms: Gm5999
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546944
Homologene: 128341
Arhgef26
Name: Rho guanine nucleotide exchange factor (GEF) 26
Synonyms: 8430436L14Rik, 4631416L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 622434
Homologene: 9204
Cacna2d4
Name: calcium channel, voltage-dependent, alpha 2/delta subunit 4
Synonyms: 5730412N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 319734
Homologene: 26544
Ccdc40
Name: coiled-coil domain containing 40
Synonyms: B930008I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 207607
Homologene: 27890
Arhgap15
Name: Rho GTPase activating protein 15
Synonyms: 5830480G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76117
Homologene: 41271
Lipk
Name: lipase, family member K
Synonyms: Lipl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240633
VEGA: 19
Homologene: 75666
Fap
Name: fibroblast activation protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14089
HGNC: HGNC:3590
Homologene: 48282
Gad1-ps
Name: glutamate decarboxylase 1, pseudogene
Synonyms: Gad-1ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 382407
VEGA: 10
Actg2
Name: actin, gamma 2, smooth muscle, enteric
Synonyms: SMGA, Act-4, Act4, Acta3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11468
HGNC: HGNC:145
Homologene: 123845
Ccr9
Name: chemokine (C-C motif) receptor 9
Synonyms: GPR-9-6, Cmkbr10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12769
HGNC: HGNC:1610
Homologene: 22546
Pom121l2
Name: POM121 membrane glycoprotein-like 2 (rat)
Synonyms: LOC195236
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 195236
Homologene: 123536
Det1
Name: de-etiolated homolog 1 (Arabidopsis)
Synonyms: 2610034H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76375
Homologene: 9952
Or6c2
Name: olfactory receptor family 6 subfamily C member 2
Synonyms: GA_x6K02T2PULF-11205096-11206034, MOR114-1, Olfr791
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258932
Homologene: 71950
Gnl1
Name: guanine nucleotide binding protein-like 1
Synonyms: Gna-rs1, Gnal1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14670
HGNC: HGNC:4413
Homologene: 3862
Meltf
Name: melanotransferrin
Synonyms: MTf, CD228, melanotransferrin, Mfi2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 30060
VEGA: 16
HGNC: HGNC:7037
Homologene: 4335
Gpat3
Name: glycerol-3-phosphate acyltransferase 3
Synonyms: A230097K15Rik, 4933407I02Rik, Agpat9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231510
Homologene: 13099
Psmb3
Name: proteasome (prosome, macropain) subunit, beta type 3
Synonyms: C10-II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 26446
HGNC: HGNC:9540
Homologene: 2089
Nectin4
Name: nectin cell adhesion molecule 4
Synonyms: nectin 4, Prr4, 1200017F15Rik, Pvrl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71740
Homologene: 32744
Or4p22
Name: olfactory receptor family 4 subfamily P member 22
Synonyms: GA_x6K02T2Q125-49974190-49975125, MOR225-3, Olfr1184
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258820
Homologene: 73980
Gm20939
Name: predicted gene, 20939
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100044193
VEGA: 17
Pcdhac2
Name: protocadherin alpha subfamily C, 2
Synonyms: CNRc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 353237
HGNC: HGNC:8677
Homologene: 49562
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 15,819,664 bp
  • T to C, chromosome 1 at 36,348,957 bp
  • G to C, chromosome 1 at 88,277,215 bp
  • C to A, chromosome 1 at 118,853,302 bp
  • T to C, chromosome 1 at 134,599,073 bp
  • T to A, chromosome 1 at 171,385,170 bp
  • A to G, chromosome 2 at 26,439,637 bp
  • G to A, chromosome 2 at 27,461,572 bp
  • G to A, chromosome 2 at 44,322,727 bp
  • A to T, chromosome 2 at 62,536,963 bp
  • G to A, chromosome 2 at 88,487,097 bp
  • A to G, chromosome 2 at 91,154,433 bp
  • T to C, chromosome 3 at 62,377,654 bp
  • T to A, chromosome 3 at 88,912,885 bp
  • C to T, chromosome 3 at 123,343,085 bp
  • T to C, chromosome 3 at 123,343,142 bp
  • T to A, chromosome 3 at 129,276,757 bp
  • A to T, chromosome 4 at 28,946,217 bp
  • A to G, chromosome 4 at 108,513,187 bp
  • G to A, chromosome 5 at 52,743,564 bp
  • A to T, chromosome 5 at 100,885,942 bp
  • A to G, chromosome 5 at 114,272,992 bp
  • A to T, chromosome 6 at 56,725,102 bp
  • A to G, chromosome 6 at 83,520,772 bp
  • T to C, chromosome 6 at 119,343,531 bp
  • A to G, chromosome 7 at 23,606,806 bp
  • C to T, chromosome 7 at 78,843,210 bp
  • T to A, chromosome 8 at 47,512,607 bp
  • A to G, chromosome 9 at 21,586,999 bp
  • A to G, chromosome 9 at 75,167,206 bp
  • A to G, chromosome 9 at 121,443,637 bp
  • A to C, chromosome 9 at 123,780,099 bp
  • C to T, chromosome 10 at 88,919,428 bp
  • T to C, chromosome 10 at 99,445,039 bp
  • A to T, chromosome 10 at 129,526,749 bp
  • A to T, chromosome 11 at 50,384,680 bp
  • A to G, chromosome 11 at 97,706,833 bp
  • A to G, chromosome 11 at 119,237,927 bp
  • A to T, chromosome 12 at 65,148,852 bp
  • T to C, chromosome 12 at 80,184,844 bp
  • G to A, chromosome 13 at 21,984,255 bp
  • G to A, chromosome 15 at 41,096,071 bp
  • G to A, chromosome 16 at 15,810,770 bp
  • A to G, chromosome 16 at 31,881,926 bp
  • T to C, chromosome 16 at 45,127,445 bp
  • C to T, chromosome 16 at 48,818,066 bp
  • T to C, chromosome 17 at 35,982,555 bp
  • G to T, chromosome 17 at 40,207,396 bp
  • T to C, chromosome 17 at 65,803,968 bp
  • C to A, chromosome 17 at 94,875,779 bp
  • T to A, chromosome 18 at 24,665,995 bp
  • C to A, chromosome 18 at 37,145,446 bp
  • A to G, chromosome 19 at 6,963,220 bp
  • T to A, chromosome 19 at 34,032,327 bp
  • A to G, chromosome 19 at 44,790,722 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5661 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043304-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.