Strain Name:
C57BL/6J-MtgxR5666Btlr
Stock Number:
043309-MU
Citation ID:
RRID:MMRRC_043309-MU
Other Names:
R5666 (G1)
Major Collection:

Gene Information

Pde1c
Name: phosphodiesterase 1C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18575
HGNC: HGNC:8776
Homologene: 3682
Sstr2
Name: somatostatin receptor 2
Synonyms: SSTR-2, sst2, Smstr2, Smstr-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20606
Homologene: 37427
Foxm1
Name: forkhead box M1
Synonyms: Mpm2, WIN, HFH-11B, Trident, Fkh16, Foxm1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14235
HGNC: HGNC:3818
Homologene: 7318
Abce1
Name: ATP-binding cassette, sub-family E (OABP), member 1
Synonyms: RNS4l (Eye), Oabp, Rnaseli
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 24015
HGNC: HGNC:69
Homologene: 2205
Slc4a2
Name: solute carrier family 4 (anion exchanger), member 2
Synonyms: B3RP, Ae2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20535
Homologene: 128699
Fzd6
Name: frizzled class receptor 6
Synonyms: Fz6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14368
VEGA: 15
HGNC: HGNC:4044
Homologene: 2617
Nmt1
Name: N-myristoyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18107
HGNC: HGNC:7857
Homologene: 69027
Bop1
Name: block of proliferation 1
Synonyms: Erb1p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12181
VEGA: 15
Homologene: 6612
Trim24
Name: tripartite motif-containing 24
Synonyms: Tif1a, D430004I05Rik, A130082H20Rik, TIF1alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21848
Homologene: 20830
Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
Synonyms: Nrf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18024
HGNC: HGNC:7782
Homologene: 2412
Ndc1
Name: NDC1 transmembrane nucleoporin
Synonyms: 2810475A17Rik, Tmem48, sks
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72787
Homologene: 41224
Phldb1
Name: pleckstrin homology like domain, family B, member 1
Synonyms: LL5A, D330037A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102693
Homologene: 15903
Rnd2
Name: Rho family GTPase 2
Synonyms: Arhn, Rohn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11858
Homologene: 21123
Btla
Name: B and T lymphocyte associated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208154
Homologene: 52233
Chd2
Name: chromodomain helicase DNA binding protein 2
Synonyms: 2810040A01Rik, 2810013C04Rik, 5630401D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244059
HGNC: HGNC:1917
Homologene: 37462
Gfpt1
Name: glutamine fructose-6-phosphate transaminase 1
Synonyms: GFAT, GFA, GFAT1, 2810423A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14583
HGNC: HGNC:4241
Homologene: 68220
Steap2
Name: six transmembrane epithelial antigen of prostate 2
Synonyms: 4921538B17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74051
Homologene: 17682
Cpxm2
Name: carboxypeptidase X 2 (M14 family)
Synonyms: 4632435C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 55987
Homologene: 69259
Hspa9
Name: heat shock protein 9
Synonyms: mortalin, Hsp74a, Hsp74, Hsc74, PBP74, GRP75, mthsp70, mot-2, Hspa9a, C3H-specific antigen, CSA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 15526
HGNC: HGNC:5244
Homologene: 39452
Ilkap
Name: integrin-linked kinase-associated serine/threonine phosphatase 2C
Synonyms: 1600009O09Rik, PP2C-DELTA, 0710007A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67444
Homologene: 31525
Pdgfra
Name: platelet derived growth factor receptor, alpha polypeptide
Synonyms: CD140a, Pdgfr-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18595
HGNC: HGNC:8803
Homologene: 31361
Col4a4
Name: collagen, type IV, alpha 4
Synonyms: [a]4(IV), E130010M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12829
HGNC: HGNC:2206
Homologene: 20071
E2f1
Name: E2F transcription factor 1
Synonyms: E2F-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13555
HGNC: HGNC:3113
Homologene: 3828
Rgs21
Name: regulator of G-protein signalling 21
Synonyms: EG624910
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 624910
Homologene: 82452
Bmper
Name: BMP-binding endothelial regulator
Synonyms: Cv2, 3110056H04Rik, CV-2, Crim3, crossveinless-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73230
VEGA: 9
Homologene: 12494
Cmya5
Name: cardiomyopathy associated 5
Synonyms: Myospryn, 2310076E16Rik, 2310076E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, syne-2, D12Ertd777e, 6820443O06Rik, Nesp2g, Cpfl8, diminished cone electroretinogram, dice
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Zfp648
Name: zinc finger protein 648
Synonyms: LOC207678, Gm10178
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100503355
Homologene: 18996
Glce
Name: glucuronyl C5-epimerase
Synonyms: heparan sulfate-glucuronic acid C5-epimerase, Hsepi, C130034A12Rik, 1110017N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 93683
Homologene: 14111
Chd3
Name: chromodomain helicase DNA binding protein 3
Synonyms: Mi-2 alpha, Prp9-1, Prp7, 2600010P09Rik, Chd7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216848
HGNC: HGNC:1918
Homologene: 62693
Or1j20
Name: olfactory receptor family 1 subfamily J member 20
Synonyms: GA_x6K02T2NLDC-33564136-33565083, MOR136-10, Olfr352
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258942
Homologene: 121523
Sptbn5
Name: spectrin beta, non-erythrocytic 5
Synonyms: EG640524, Spnb5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 640524
Homologene: 41150
Dscam
Name: DS cell adhesion molecule
Synonyms: 4932410A21Rik, Down syndrome cell adhesion molecule
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Ephb3
Name: Eph receptor B3
Synonyms: Sek4, MDK5, HEK2, Etk2, Tyro6, Cek10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13845
HGNC: HGNC:3394
Homologene: 20938
Nadsyn1
Name: NAD synthetase 1
Synonyms: 9130012B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78914
Homologene: 6098
Vmn2r10
Name: vomeronasal 2, receptor 10
Synonyms: VR16, V2r16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22307
Homologene: 129606
Or5k1
Name: olfactory receptor family 5 subfamily K member 1
Synonyms: GA_x54KRFPKG5P-54960233-54959268, MOR184-3, Olfr173
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 259002
Homologene: 45084
Hs2st1
Name: heparan sulfate 2-O-sulfotransferase 1
Synonyms: Hs2st
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 23908
HGNC: HGNC:5193
Homologene: 8025
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: MyHC-IId/x, Myhs-f, Myhs-f2, Myhsf2, MYHC-IIX, myosin heavy chain 2X, IId, IId/x, A530084A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Ddb2
Name: damage specific DNA binding protein 2
Synonyms: p48, 2610043A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 107986
HGNC: HGNC:2718
Homologene: 83
Cap2
Name: CAP, adenylate cyclase-associated protein, 2 (yeast)
Synonyms: 2810452G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67252
Homologene: 101397
Slc7a4
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224022
Homologene: 20883
Gm4787
Name: predicted gene 4787
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 214321
Homologene: 86950
Lpin3
Name: lipin 3
Synonyms: 9130206L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 64899
Homologene: 84844
Palmd
Name: palmdelphin
Synonyms: PALML, 4631423C22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 114301
Homologene: 9804
Cyp2j5
Name: cytochrome P450, family 2, subfamily j, polypeptide 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13109
HGNC: HGNC:2634
Homologene: 116530
Padi2
Name: peptidyl arginine deiminase, type II
Synonyms: PAD type II, Pdi, Pdi2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18600
Homologene: 7214
Tmprss13
Name: transmembrane protease, serine 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214531
Homologene: 12936
Or4b12
Name: olfactory receptor family 4 subfamily B member 12
Synonyms: GA_x6K02T2Q125-51620802-51619885, MOR227-5, Olfr1271
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258789
HGNC: HGNC:8290
Fkbp10
Name: FK506 binding protein 10
Synonyms: FKBP65, Fkbp1-rs, Fkbp-rs1, Fkbp6, 65kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14230
Homologene: 7718
Or2y8
Name: olfactory receptor family 2 subfamily Y member 8
Synonyms: GA_x6K02T2QP88-3283154-3284089, MOR256-69_p, Olfr1373
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 211472
Homologene: 72463
Dtd2
Name: D-tyrosyl-tRNA deacylase 2
Synonyms: 4930578F06Rik, B830049N13Rik, 6530401N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 328092
Homologene: 12634
Pla2g2d
Name: phospholipase A2, group IID
Synonyms: mGIID, Splash
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18782
HGNC: HGNC:9033
Homologene: 7892
Nkain4
Name: Na+/K+ transporting ATPase interacting 4
Synonyms: C030019F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 58237
Homologene: 10978
Ikzf2
Name: IKAROS family zinc finger 2
Synonyms: Helios, Zfpn1a2, A730095J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22779
Homologene: 22659
4930524J08Rik
Name: RIKEN cDNA 4930524J08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75129
Vwa1
Name: von Willebrand factor A domain containing 1
Synonyms: WARP, 4932416A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 246228
Homologene: 11270
Tas2r130
Name: taste receptor, type 2, member 130
Synonyms: Tas2r30, STC 7-4, mt2r42, T2R30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387355
Homologene: 41536
Ndufaf4
Name: NADH:ubiquinone oxidoreductase complex assembly factor 4
Synonyms: 3000003G13Rik, 1110007M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68493
Homologene: 40928
Gm38100
Name: predicted gene, 38100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
4933413G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 69,577,900 bp
  • A to G, chromosome 1 at 82,485,579 bp
  • T to C, chromosome 1 at 91,391,141 bp
  • A to G, chromosome 1 at 144,536,942 bp
  • C to A, chromosome 1 at 154,204,217 bp
  • C to T, chromosome 1 at 175,921,613 bp
  • T to A, chromosome 2 at 36,870,389 bp
  • T to C, chromosome 2 at 75,677,118 bp
  • T to C, chromosome 2 at 90,265,964 bp
  • C to T, chromosome 2 at 91,212,581 bp
  • C to G, chromosome 2 at 120,085,567 bp
  • T to A, chromosome 2 at 154,569,181 bp
  • A to G, chromosome 2 at 160,897,330 bp
  • A to G, chromosome 2 at 180,943,202 bp
  • T to C, chromosome 3 at 116,924,101 bp
  • A to T, chromosome 3 at 144,569,793 bp
  • A to T, chromosome 4 at 24,898,636 bp
  • C to T, chromosome 4 at 96,658,693 bp
  • T to C, chromosome 4 at 107,389,526 bp
  • T to A, chromosome 4 at 138,780,280 bp
  • G to T, chromosome 4 at 140,949,231 bp
  • A to G, chromosome 4 at 155,774,465 bp
  • C to T, chromosome 5 at 5,673,681 bp
  • G to T, chromosome 5 at 24,434,838 bp
  • T to C, chromosome 5 at 75,173,495 bp
  • T to C, chromosome 5 at 99,979,209 bp
  • A to T, chromosome 5 at 108,999,044 bp
  • T to C, chromosome 6 at 37,965,601 bp
  • A to C, chromosome 6 at 56,126,857 bp
  • A to T, chromosome 6 at 87,053,813 bp
  • C to T, chromosome 6 at 128,373,167 bp
  • T to C, chromosome 6 at 128,375,555 bp
  • T to C, chromosome 6 at 131,630,379 bp
  • A to T, chromosome 7 at 73,441,717 bp
  • C to T, chromosome 7 at 132,054,896 bp
  • C to T, chromosome 7 at 143,807,431 bp
  • C to A, chromosome 8 at 79,690,277 bp
  • T to A, chromosome 9 at 23,473,463 bp
  • T to C, chromosome 9 at 44,715,781 bp
  • A to G, chromosome 9 at 45,344,955 bp
  • A to G, chromosome 9 at 62,060,511 bp
  • A to C, chromosome 11 at 52,144,698 bp
  • T to A, chromosome 11 at 67,221,352 bp
  • T to C, chromosome 11 at 69,353,351 bp
  • G to T, chromosome 11 at 100,423,526 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • C to T, chromosome 11 at 103,058,215 bp
  • T to A, chromosome 11 at 113,624,713 bp
  • T to A, chromosome 12 at 51,999,860 bp
  • G to A, chromosome 12 at 75,950,959 bp
  • G to A, chromosome 12 at 81,378,031 bp
  • T to A, chromosome 13 at 46,531,083 bp
  • T to C, chromosome 13 at 93,045,949 bp
  • A to T, chromosome 15 at 39,031,115 bp
  • T to C, chromosome 15 at 76,454,233 bp
  • A to G, chromosome 16 at 17,575,951 bp
  • A to G, chromosome 16 at 21,222,491 bp
  • A to T, chromosome 16 at 45,250,419 bp
  • G to A, chromosome 16 at 58,797,061 bp
  • G to A, chromosome 16 at 96,718,164 bp
  • T to C, chromosome 18 at 34,954,247 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5666 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043309-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.