Strain Name:
C57BL/6J-MtgxR5667Btlr
Stock Number:
043310-MU
Citation ID:
RRID:MMRRC_043310-MU
Other Names:
R5667 (G1)
Major Collection:

Gene Information

Mycn
Name: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
Synonyms: Nmyc1, N-myc, Nmyc-1, Nmyc, bHLHe37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 18109
HGNC: HGNC:7559
Homologene: 3922
Lrrn3
Name: leucine rich repeat protein 3, neuronal
Synonyms: NLRR-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 16981
VEGA: 12
Homologene: 36315
Ak2
Name: adenylate kinase 2
Synonyms: Ak-2, D4Ertd220e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11637
HGNC: HGNC:362
Homologene: 1227
Cyfip1
Name: cytoplasmic FMR1 interacting protein 1
Synonyms: l7Rl1, Sra-1, P140SRA-1, pl-1, Shyc, l(7)1Rl, E030028J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20430
Homologene: 22628
Washc4
Name: WASH complex subunit 4
Synonyms: A230046K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 319277
VEGA: 10
Homologene: 123926
Flnb
Name: filamin, beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 286940
HGNC: HGNC:3755
Homologene: 37480
Gpa33
Name: glycoprotein A33 (transmembrane)
Synonyms: A33 antigen, 2210401D16Rik, 2010310L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 59290
HGNC: HGNC:4445
Homologene: 4245
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: FSA, Tweek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229227
Homologene: 52105
Akap8l
Name: A kinase (PRKA) anchor protein 8-like
Synonyms: Nakap95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 54194
VEGA: 17
Homologene: 8658
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20191
VEGA: 13
Homologene: 37423
Foxi2
Name: forkhead box I2
Synonyms: B130055A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 270004
Homologene: 18838
Lmbr1l
Name: limb region 1 like
Synonyms: 1110013E13Rik, D15Ertd735e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 74775
Homologene: 10011
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 236266
HGNC: HGNC:428
Homologene: 49406
Trpv4
Name: transient receptor potential cation channel, subfamily V, member 4
Synonyms: VRL-2, Trp12, VROAC, OTRPC4, VR-OAC, 0610033B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 63873
Homologene: 11003
Kank4
Name: KN motif and ankyrin repeat domains 4
Synonyms: Ankrd38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242553
Homologene: 18244
Clca4b
Name: chloride channel accessory 4B
Synonyms: AI747448
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99709
HGNC: HGNC:2018
Homologene: 40808
Chordc1
Name: cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
Synonyms: morgana, 1110001O09Rik, Chp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 66917
VEGA: 9
Homologene: 8111
Btbd10
Name: BTB (POZ) domain containing 10
Synonyms: 1110056N09Rik, Gmrp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68815
Homologene: 13009
2700049A03Rik
Name: RIKEN cDNA 2700049A03 gene
Synonyms: talpid3, Ta3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 76967
Homologene: 8839
Usp8
Name: ubiquitin specific peptidase 8
Synonyms: Ubpy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 84092
Homologene: 3782
D430042O09Rik
Name: RIKEN cDNA D430042O09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233865
Homologene: 45841
Atp8b1
Name: ATPase, class I, type 8B, member 1
Synonyms: Ic, FIC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 54670
VEGA: 18
HGNC: HGNC:3706
Homologene: 21151
Slc11a2
Name: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
Synonyms: van, microcytic anemia, viable anaemia, DCT1, DMT1, Nramp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18174
Homologene: 55471
Capn11
Name: calpain 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268958
HGNC: HGNC:1478
Homologene: 21392
Lama2
Name: laminin, alpha 2
Synonyms: mer, merosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Nalcn
Name: sodium leak channel, non-selective
Synonyms: A530023G15Rik, Vgcnl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 338370
VEGA: 14
Homologene: 21832
BC003965
Name: cDNA sequence BC003965
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 214489
VEGA: 17
Homologene: 52829
Ly75
Name: lymphocyte antigen 75
Synonyms: CD205, DEC-205
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17076
HGNC: HGNC:6729
Homologene: 31085
Adamts16
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 271127
Homologene: 15146
Olfr1285
Name: olfactory receptor 1285
Synonyms: MOR248-17P, GA_x6K02T2Q125-72459956-72460837, MOR248-25_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 545447
Nod1
Name: nucleotide-binding oligomerization domain containing 1
Synonyms: Nlrc1, Card4, F830007N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 107607
Homologene: 4440
Ivns1abp
Name: influenza virus NS1A binding protein
Synonyms: NS1-BP, HSPC068, Nd1-L, Nd1-S, NS-1, 1700126I16Rik, ND1, 1190004M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 117198
Homologene: 31384
Atxn1
Name: ataxin 1
Synonyms: Sca1, Atx1, 2900016G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20238
VEGA: 13
Homologene: 281
Tmc6
Name: transmembrane channel-like gene family 6
Synonyms: EVER1, D11Ertd204e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217353
Homologene: 5258
Ptpru
Name: protein tyrosine phosphatase, receptor type, U
Synonyms: Ptprl, RPTPlambda
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Gad1-ps
Name: glutamate decarboxylase 1, pseudogene
Synonyms: Gad-1ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 382407
VEGA: 10
Ifna6
Name: interferon alpha 6
Synonyms: Ifna8, Ifa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 15969
HGNC: HGNC:5425
Homologene: 68536
Gpr45
Name: G protein-coupled receptor 45
Synonyms: 9230112G11Rik, PSP24alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 93690
HGNC: HGNC:4503
Homologene: 5228
Exoc3l4
Name: exocyst complex component 3-like 4
Synonyms: 1600013K19Rik, 1200009I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 74190
VEGA: 12
Homologene: 41760
Arhgap24
Name: Rho GTPase activating protein 24
Synonyms: 0610025G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231532
Homologene: 32754
Clip4
Name: CAP-GLY domain containing linker protein family, member 4
Synonyms: Rsnl2, 1700024K14Rik, 1700074B05Rik, 5830409B12Rik, 4833417L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78785
VEGA: 17
Homologene: 11662
Arhgap45
Name: Rho GTPase activating protein 45
Synonyms: Hmha1, 6330406L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70719
Homologene: 69120
4930444G20Rik
Name: RIKEN cDNA 4930444G20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 114671
Homologene: 130042
H2-Eb1
Name: histocompatibility 2, class II antigen E beta
Synonyms: H-2Eb, Ia-4, Ia4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14969
HGNC: HGNC:4953
Homologene: 101524
Cyp4v3
Name: cytochrome P450, family 4, subfamily v, polypeptide 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 102294
Homologene: 133054
Slc22a6
Name: solute carrier family 22 (organic anion transporter), member 6
Synonyms: Orctl1, mOat1, Oat1, NKT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18399
VEGA: 19
Homologene: 16813
Plekhg2
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Synonyms: Clg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101497
Homologene: 16341
Styxl1
Name: serine/threonine/tyrosine interacting-like 1
Synonyms: Dusp24, 1700011C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 76571
Homologene: 9378
Foxa1
Name: forkhead box A1
Synonyms: Hnf-3a, Tcf3a, Tcf-3a, Hnf3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 15375
VEGA: 12
HGNC: HGNC:5021
Homologene: 3307
H2-Ke6
Name: H2-K region expressed gene 6
Synonyms: Ring2, H-2Ke6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14979
HGNC: HGNC:3554
Homologene: 56588
Olfr1388
Name: olfactory receptor 1388
Synonyms: MOR256-28, GA_x6K02T2QP88-5991012-5990077
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258459
Homologene: 74258
Rpl36al
Name: ribosomal protein L36A-like
Synonyms: 2410038A03Rik, RPL36A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 66483
Homologene: 133572
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 43,033,058 bp
  • G to T, chromosome 1 at 151,354,009 bp
  • A to G, chromosome 1 at 166,146,791 bp
  • T to C, chromosome 2 at 60,308,311 bp
  • C to T, chromosome 2 at 111,408,473 bp
  • A to G, chromosome 2 at 126,742,425 bp
  • A to T, chromosome 3 at 36,917,677 bp
  • G to A, chromosome 3 at 144,921,863 bp
  • A to T, chromosome 4 at 88,827,669 bp
  • A to G, chromosome 4 at 98,765,461 bp
  • T to A, chromosome 4 at 129,008,247 bp
  • T to A, chromosome 4 at 131,820,190 bp
  • T to G, chromosome 5 at 102,846,171 bp
  • A to G, chromosome 5 at 114,634,556 bp
  • A to G, chromosome 5 at 135,757,123 bp
  • T to C, chromosome 6 at 54,933,576 bp
  • A to G, chromosome 6 at 85,696,771 bp
  • A to T, chromosome 7 at 28,367,639 bp
  • C to T, chromosome 7 at 55,873,730 bp
  • T to C, chromosome 7 at 113,332,724 bp
  • T to A, chromosome 7 at 125,843,455 bp
  • A to T, chromosome 7 at 135,410,939 bp
  • G to T, chromosome 8 at 45,308,535 bp
  • T to G, chromosome 9 at 18,295,332 bp
  • T to A, chromosome 10 at 22,066,843 bp
  • A to T, chromosome 10 at 27,190,544 bp
  • A to G, chromosome 10 at 80,025,476 bp
  • T to C, chromosome 10 at 83,570,028 bp
  • A to T, chromosome 10 at 99,444,533 bp
  • T to C, chromosome 11 at 49,444,313 bp
  • A to G, chromosome 11 at 117,775,615 bp
  • A to T, chromosome 12 at 12,940,044 bp
  • A to C, chromosome 12 at 41,452,298 bp
  • A to T, chromosome 12 at 57,542,295 bp
  • G to A, chromosome 12 at 69,183,123 bp
  • G to T, chromosome 12 at 71,164,546 bp
  • A to T, chromosome 12 at 71,164,547 bp
  • T to C, chromosome 12 at 111,423,417 bp
  • A to G, chromosome 13 at 11,759,836 bp
  • T to C, chromosome 13 at 45,557,377 bp
  • A to T, chromosome 13 at 70,836,375 bp
  • T to A, chromosome 14 at 7,890,843 bp
  • A to G, chromosome 14 at 123,295,406 bp
  • A to C, chromosome 15 at 98,907,608 bp
  • A to G, chromosome 15 at 100,403,288 bp
  • A to G, chromosome 16 at 32,753,720 bp
  • G to A, chromosome 17 at 25,184,989 bp
  • T to C, chromosome 17 at 32,338,292 bp
  • T to C, chromosome 17 at 34,026,461 bp
  • C to A, chromosome 17 at 34,314,255 bp
  • C to T, chromosome 17 at 45,639,674 bp
  • A to C, chromosome 17 at 71,789,883 bp
  • C to T, chromosome 18 at 64,581,923 bp
  • A to G, chromosome 19 at 8,621,784 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5667 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043310-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.