Strain Name:
C57BL/6J-MtgxR5669Btlr
Stock Number:
043312-MU
Citation ID:
RRID:MMRRC_043312-MU
Other Names:
R5669 (G1)
Major Collection:

Gene Information

Itgb8
Name: integrin beta 8
Synonyms: 4832412O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320910
HGNC: HGNC:6163
Homologene: 18567
Gpr37
Name: G protein-coupled receptor 37
Synonyms: parkin-associated endothelin B-like receptor, Pael-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14763
HGNC: HGNC:4494
Homologene: 3875
Scarb1
Name: scavenger receptor class B, member 1
Synonyms: Cla-1, Hlb398, Chohd1, Hdlq1, Chohd1, SRBI, Srb1, Cd36l1, D5Ertd460e, SR-BI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20778
HGNC: HGNC:1664
Homologene: 21132
Foxa3
Name: forkhead box A3
Synonyms: Hnf-3g, Tcf3g, Tcf-3g, Hnf3g
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15377
HGNC: HGNC:5023
Homologene: 3308
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: trabeculin alpha, Acf7, Aclp7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11426
Homologene: 136191
Mga
Name: MAX gene associated
Synonyms: C130042M01Rik, Mga, D030062C11Rik, Mad5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 29808
Homologene: 49351
Pepd
Name: peptidase D
Synonyms: dal, Pep4, peptidase D, Pep-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18624
HGNC: HGNC:8840
Homologene: 239
Pml
Name: promyelocytic leukemia
Synonyms: 1200009E24Rik, Trim19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18854
HGNC: HGNC:9113
Homologene: 13245
Cdc42bpb
Name: CDC42 binding protein kinase beta
Synonyms: DMPK-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217866
VEGA: 12
HGNC: HGNC:1738
Homologene: 55945
Ddx42
Name: DEAD box helicase 42
Synonyms: B430002H05Rik, SF3b125, 1810047H21Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72047
Homologene: 49137
Copb1
Name: coatomer protein complex, subunit beta 1
Synonyms: 2610019B04Rik, Copb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70349
HGNC: HGNC:2231
Homologene: 5664
Akap9
Name: A kinase (PRKA) anchor protein (yotiao) 9
Synonyms: AKAP450, 5730481H23Rik, G1-448-15, mei2-5, repro12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Prpf8
Name: pre-mRNA processing factor 8
Synonyms: DBF3/PRP8, Sfprp8l, D11Bwg0410e, Prp8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192159
Homologene: 4706
Prom1
Name: prominin 1
Synonyms: AC133, Prom-1, 4932416E19Rik, Prom, CD133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19126
HGNC: HGNC:9454
Homologene: 4390
Tmprss6
Name: transmembrane serine protease 6
Synonyms: 1300008A22Rik, matriptase-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71753
VEGA: 15
Homologene: 12408
Slitrk5
Name: SLIT and NTRK-like family, member 5
Synonyms: 2610019D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 75409
VEGA: 14
Homologene: 9193
Slc39a4
Name: solute carrier family 39 (zinc transporter), member 4
Synonyms: AWMS2, zip4, 1600025H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72027
VEGA: 15
Homologene: 15638
Scube2
Name: signal peptide, CUB domain, EGF-like 2
Synonyms: ICRFP703B1614Q5.1, 4932442O19Rik, Cegf1, ICRFP703N2430Q5.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56788
Homologene: 36383
Rnd2
Name: Rho family GTPase 2
Synonyms: Arhn, Rohn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11858
Homologene: 21123
Hapln3
Name: hyaluronan and proteoglycan link protein 3
Synonyms: 4930554N11Rik, Lpr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67666
Homologene: 18654
Ttf2
Name: transcription termination factor, RNA polymerase II
Synonyms: 4632434F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74044
Homologene: 37826
2700049A03Rik
Name: RIKEN cDNA 2700049A03 gene
Synonyms: Ta3, talpid3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76967
Homologene: 8839
Ppp1r13l
Name: protein phosphatase 1, regulatory subunit 13 like
Synonyms: NFkB interacting protein 1, wa3, IASPP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 333654
Homologene: 84635
Retsat
Name: retinol saturase (all trans retinol 13,14 reductase)
Synonyms: 0610039N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67442
Homologene: 41195
Dlk1
Name: delta like non-canonical Notch ligand 1
Synonyms: Peg9, pref-1, FA1, SCP1, ZOG, DlkI, pG2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13386
HGNC: HGNC:2907
Homologene: 2846
Kcnv1
Name: potassium channel, subfamily V, member 1
Synonyms: 2700023A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67498
VEGA: 15
Homologene: 22811
Aldh1a1
Name: aldehyde dehydrogenase family 1, subfamily A1
Synonyms: ALDH1, E1, Raldh1, Ahd-2, Ahd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 11668
HGNC: HGNC:402
Homologene: 110441
Ret
Name: ret proto-oncogene
Synonyms: RET9, RET51, c-Ret
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19713
HGNC: HGNC:9967
Homologene: 7517
Astl
Name: astacin-like metalloendopeptidase (M12 family)
Synonyms: Ovastacin, Sas1b, C87576
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 215095
Homologene: 128191
Pramel13
Name: PRAME like 13
Synonyms: Pramef12, 4930569K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 77632
Homologene: 135701
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Pak5
Name: p21 (RAC1) activated kinase 5
Synonyms: Pak5, Pak7, 2900083L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241656
Homologene: 22211
Nadsyn1
Name: NAD synthetase 1
Synonyms: 9130012B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78914
Homologene: 6098
Serpinb1a
Name: serine (or cysteine) peptidase inhibitor, clade B, member 1a
Synonyms: EIA, M/NEI, 1190005M04Rik, LEI, ELANH2, MNEI, ovalbumin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66222
HGNC: HGNC:3311
Homologene: 133768
Srgap1
Name: SLIT-ROBO Rho GTPase activating protein 1
Synonyms: Arhgap13, 4930572H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 117600
Homologene: 56898
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Gm7455, Col6a5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 665033
Homologene: 122792
Fbll1
Name: fibrillarin-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237730
Homologene: 28185
Olfr1115
Name: olfactory receptor 1115
Synonyms: MOR273-4P, Olfr1530-ps1, GA_x6K02T2Q125-48736906-48737886, MOR273-4P, MOR264-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258294
Homologene: 27114
Fbxw21
Name: F-box and WD-40 domain protein 21
Synonyms: E330009P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320082
Homologene: 110776
Gm14139
Name: predicted gene 14139
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 100271882
Homologene: 134546
Rnf31
Name: ring finger protein 31
Synonyms: HOIP, Paul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268749
Homologene: 33228
Kcnk3
Name: potassium channel, subfamily K, member 3
Synonyms: Task-1, cTBAK-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 16527
HGNC: HGNC:6278
Homologene: 1692
Popdc3
Name: popeye domain containing 3
Synonyms: Pop3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 78977
Homologene: 32540
Vmn1r62
Name: vomeronasal 1 receptor 62
Synonyms: V1rd8, V3R2, V1rd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 81016
Homologene: 41799
Olfr58
Name: olfactory receptor 58
Synonyms: IG6, MOR146-3, MOR146-7P, GA_x6K02T2PVTD-13523015-13523944
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18358
Homologene: 134093
Cd160
Name: CD160 antigen
Synonyms: By55
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 54215
Homologene: 5122
Pcsk1
Name: proprotein convertase subtilisin/kexin type 1
Synonyms: prohormone convertase 1/3, Nec1, PC1, SPC3, PC3, Phpp-1, Nec-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18548
HGNC: HGNC:8743
Homologene: 379
Cdip1
Name: cell death inducing Trp53 target 1
Synonyms: CDIP, 2700048O17Rik, 5730403B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 66626
Homologene: 40879
Rps6kl1
Name: ribosomal protein S6 kinase-like 1
Synonyms: A830084F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238323
VEGA: 12
Homologene: 12874
BC035947
Name: cDNA sequence BC035947
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Igkv4-54
Name: immunoglobulin kappa chain variable 4-54
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 385291
Ccdc108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Prlh
Name: prolactin releasing hormone
Synonyms: EG623503
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 623503
Homologene: 9291
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 74,924,968 bp
  • A to T, chromosome 1 at 78,497,913 bp
  • A to G, chromosome 1 at 90,953,120 bp
  • T to C, chromosome 2 at 41,111,038 bp
  • T to C, chromosome 2 at 87,252,441 bp
  • A to G, chromosome 2 at 119,903,426 bp
  • G to T, chromosome 2 at 127,347,279 bp
  • G to A, chromosome 2 at 136,116,284 bp
  • A to G, chromosome 2 at 150,192,178 bp
  • C to T, chromosome 3 at 96,808,898 bp
  • T to A, chromosome 3 at 100,951,117 bp
  • T to A, chromosome 4 at 123,476,225 bp
  • T to C, chromosome 4 at 144,395,843 bp
  • T to A, chromosome 5 at 4,050,540 bp
  • A to G, chromosome 5 at 30,622,349 bp
  • A to G, chromosome 5 at 44,012,943 bp
  • A to G, chromosome 5 at 125,300,387 bp
  • A to T, chromosome 6 at 25,669,352 bp
  • A to G, chromosome 6 at 69,631,848 bp
  • A to G, chromosome 6 at 72,606,010 bp
  • T to C, chromosome 6 at 118,184,243 bp
  • T to A, chromosome 7 at 5,675,737 bp
  • T to C, chromosome 7 at 19,014,251 bp
  • A to C, chromosome 7 at 19,373,022 bp
  • T to C, chromosome 7 at 35,040,674 bp
  • G to T, chromosome 7 at 79,117,496 bp
  • C to T, chromosome 7 at 109,825,439 bp
  • A to G, chromosome 7 at 114,237,585 bp
  • C to T, chromosome 7 at 143,807,431 bp
  • T to C, chromosome 9 at 19,783,757 bp
  • C to T, chromosome 9 at 58,247,063 bp
  • A to G, chromosome 9 at 105,925,998 bp
  • A to T, chromosome 9 at 109,145,510 bp
  • T to A, chromosome 10 at 45,316,433 bp
  • C to A, chromosome 10 at 121,804,850 bp
  • T to C, chromosome 11 at 35,797,584 bp
  • T to A, chromosome 11 at 75,504,738 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • A to T, chromosome 11 at 106,241,819 bp
  • T to C, chromosome 11 at 119,458,785 bp
  • G to T, chromosome 12 at 71,164,546 bp
  • A to T, chromosome 12 at 71,164,547 bp
  • T to C, chromosome 12 at 85,147,867 bp
  • T to C, chromosome 12 at 109,460,038 bp
  • C to T, chromosome 12 at 111,302,013 bp
  • T to A, chromosome 12 at 119,190,628 bp
  • A to G, chromosome 13 at 32,845,316 bp
  • T to A, chromosome 13 at 75,130,102 bp
  • C to T, chromosome 14 at 55,596,704 bp
  • A to G, chromosome 14 at 111,681,623 bp
  • T to C, chromosome 15 at 45,114,252 bp
  • A to C, chromosome 15 at 76,614,163 bp
  • A to T, chromosome 15 at 78,454,956 bp
  • T to A, chromosome 16 at 4,768,815 bp
  • T to C, chromosome 19 at 20,610,920 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5669 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043312-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.