Strain Name:
C57BL/6J-MtgxR5717Btlr
Stock Number:
043337-MU
Citation ID:
RRID:MMRRC_043337-MU
Other Names:
R5717 (G1)
Major Collection:

Gene Information

B4galt5
Name: UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
Synonyms: 9430078I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56336
HGNC: HGNC:928
Homologene: 3507
Dicer1
Name: dicer 1, ribonuclease type III
Synonyms: D12Ertd7e, 1110006F08Rik, Dicer1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 192119
VEGA: 12
Homologene: 13251
Epha2
Name: Eph receptor A2
Synonyms: Sek-2, Myk2, Eck, Sek2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13836
HGNC: HGNC:3386
Homologene: 20929
Rps25
Name: ribosomal protein S25
Synonyms: 2810009D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 75617
VEGA: 9
Homologene: 133893
Zfp423
Name: zinc finger protein 423
Synonyms: ataxia1, Roaz, Ebfaz, Zfp104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 94187
Homologene: 9010
Senp6
Name: SUMO/sentrin specific peptidase 6
Synonyms: 2810017C20Rik, E130319N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 215351
Homologene: 9196
Ppp2r5d
Name: protein phosphatase 2, regulatory subunit B', delta
Synonyms: B'delta, Tex271, TEG-271
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21770
VEGA: 17
HGNC: HGNC:9312
Homologene: 37661
Ankrd11
Name: ankyrin repeat domain 11
Synonyms: 3010027A04Rik, Yod, 9530048I21Rik, 2410104C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 77087
Homologene: 69134
Cry1
Name: cryptochrome 1 (photolyase-like)
Synonyms: Phll1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 12952
VEGA: 10
HGNC: HGNC:2384
Homologene: 7042
Sec24a
Name: Sec24 related gene family, member A (S. cerevisiae)
Synonyms: 9430090N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 77371
Homologene: 70131
Rnf123
Name: ring finger protein 123
Synonyms: KPC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 84585
Homologene: 11112
Slc49a4
Name: solute carrier family 49 member 4
Synonyms: RCC4, Dirc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224132
Homologene: 13137
Hr
Name: lysine demethylase and nuclear receptor corepressor
Synonyms: N, rh, rh-bmh, ba, bldy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 15460
HGNC: HGNC:5172
Homologene: 3774
Adnp2
Name: ADNP homeobox 2
Synonyms: Zfp508, 8430420L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240442
Homologene: 8945
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: Sema6A-1, sema, A730020P05Rik, VIa, Semaq
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 20358
Homologene: 32426
Adgrl4
Name: adhesion G protein-coupled receptor L4
Synonyms: 1110033N21Rik, EGF-TM7 receptor, Etl, Eltd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 170757
Homologene: 11170
Frmd8
Name: FERM domain containing 8
Synonyms: 2310035N23Rik, 1200004M23Rik, iTAP, 4931429L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 67457
Homologene: 32653
Ckap2
Name: cytoskeleton associated protein 2
Synonyms: LB1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 80986
HGNC: HGNC:1990
Homologene: 10070
Wdr72
Name: WD repeat domain 72
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 546144
Homologene: 52326
Itga11
Name: integrin alpha 11
Synonyms: 4732459H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319480
HGNC: HGNC:6136
Homologene: 8151
Bbs1
Name: Bardet-Biedl syndrome 1 (human)
Synonyms: D19Ertd609e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 52028
VEGA: 19
HGNC: HGNC:966
Homologene: 11641
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: myosin heavy chain 2X, IId, IId/x, Myhsf2, Myhs-f, Myhs-f2, MyHC-IId/x, A530084A17Rik, MYHC-IIX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: E130113P14Rik, bl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231470
Homologene: 23516
Cspg4
Name: chondroitin sulfate proteoglycan 4
Synonyms: NG2, AN2, 4732461B14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 121021
VEGA: 9
HGNC: HGNC:2466
Homologene: 20445
Mypn
Name: myopalladin
Synonyms: 1110056A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 68802
VEGA: 10
Homologene: 23778
Matn2
Name: matrilin 2
Synonyms: Crtm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 17181
VEGA: 15
HGNC: HGNC:6908
Homologene: 20538
Olfr1209
Name: olfactory receptor 1209
Synonyms: MOR230-7, GA_x6K02T2Q125-50386882-50385950
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258453
Homologene: 128155
Cenpj
Name: centromere protein J
Synonyms: 4932437H03Rik, Sas4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219103
Homologene: 10204
Zfp759
Name: zinc finger protein 759
Synonyms: Rslcan-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 268670
VEGA: 13
Ptprr
Name: protein tyrosine phosphatase, receptor type, R
Synonyms: PTP-SL, RPTPRR, PTPBR7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 19279
HGNC: HGNC:9680
Homologene: 2135
Ptgis
Name: prostaglandin I2 (prostacyclin) synthase
Synonyms: Cyp8a1, Pgis, Pgi2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19223
HGNC: HGNC:9603
Homologene: 37374
Vmn2r17
Name: vomeronasal 2, receptor 17
Synonyms: EG384221
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 384221
Homologene: 104825
Foxc1
Name: forkhead box C1
Synonyms: frkhda, FREAC3, fkh-1, Mf4, Fkh1, fkh1, Mf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17300
HGNC: HGNC:3800
Homologene: 20373
Vmn1r43
Name: vomeronasal 1 receptor 43
Synonyms: V1ra5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 113847
Homologene: 130651
Hyal6
Name: hyaluronoglucosaminidase 6
Synonyms: Hyal-ps1, 4932701A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 74409
HGNC: HGNC:5324
Homologene: 78028
Olfr284
Name: olfactory receptor 284
Synonyms: MOR160-4, GA_x6K02T2NBG7-5395976-5396893
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 258278
Homologene: 74250
4933411K16Rik
Name: RIKEN cDNA 4933411K16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 66765
Homologene: 83936
Stoml3
Name: stomatin (Epb7.2)-like 3
Synonyms: SLP3, SRO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229277
Homologene: 16628
Msgn1
Name: mesogenin 1
Synonyms: Msgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 56184
VEGA: 12
Homologene: 10466
Klk1b16
Name: kallikrein 1-related peptidase b16
Synonyms: mGk-16, Klk16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16615
HGNC: HGNC:6364
Homologene: 68141
Acss2
Name: acyl-CoA synthetase short-chain family member 2
Synonyms: Acs1, AceCS1, acetyl-CoA synthetase 1, Acas1, ACAS, Acas2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 60525
Homologene: 6469
Olfr235
Name: olfactory receptor 235
Synonyms: GA_x6K02T057QT-4025-4642, GA_x6K02T03CT6-1-477, Olfr245, GA_x6K02T2LL2P-1028-792, MOR214-3, Olfr232, MOR214-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258681
Gm5218
Name: predicted gene 5218
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 108168218
VEGA: 15
Gm7735
Name: predicted gene 7735
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 102637417
VEGA: 16
Rpl6l
Name: ribosomal protein L6-like
Synonyms: Gm5428
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 432502
VEGA: 10
Homologene: 31001
Igkv6-20
Name: immunoglobulin kappa variable 6-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 108024
Igkv8-27
Name: immunoglobulin kappa chain variable 8-27
Synonyms: Gm16944
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 434041
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 2 at 76,747,747 bp
  • T to C, chromosome 2 at 88,910,022 bp
  • T to C, chromosome 2 at 155,561,153 bp
  • C to T, chromosome 2 at 167,208,364 bp
  • G to A, chromosome 2 at 167,306,629 bp
  • A to T, chromosome 3 at 53,505,516 bp
  • T to C, chromosome 3 at 151,492,334 bp
  • A to T, chromosome 4 at 141,322,071 bp
  • T to C, chromosome 5 at 96,781,737 bp
  • C to T, chromosome 5 at 109,427,274 bp
  • T to C, chromosome 6 at 24,743,691 bp
  • T to A, chromosome 6 at 70,171,934 bp
  • T to A, chromosome 6 at 70,336,428 bp
  • T to C, chromosome 6 at 89,869,923 bp
  • A to G, chromosome 7 at 44,139,489 bp
  • T to C, chromosome 8 at 22,175,047 bp
  • A to T, chromosome 8 at 87,686,559 bp
  • T to C, chromosome 8 at 122,892,638 bp
  • A to G, chromosome 9 at 44,408,750 bp
  • G to T, chromosome 9 at 56,885,798 bp
  • A to G, chromosome 9 at 62,752,249 bp
  • T to A, chromosome 9 at 74,148,205 bp
  • A to T, chromosome 9 at 80,092,312 bp
  • G to A, chromosome 9 at 108,067,424 bp
  • A to G, chromosome 10 at 63,127,776 bp
  • A to T, chromosome 10 at 85,146,416 bp
  • T to C, chromosome 10 at 111,126,023 bp
  • A to G, chromosome 10 at 116,048,113 bp
  • A to G, chromosome 11 at 51,707,210 bp
  • A to G, chromosome 11 at 67,208,956 bp
  • T to C, chromosome 12 at 11,208,518 bp
  • T to A, chromosome 12 at 104,705,128 bp
  • C to T, chromosome 13 at 31,807,488 bp
  • T to A, chromosome 13 at 67,138,708 bp
  • GTTTT to GTTTTT, chromosome 14 at 56,553,521 bp
  • C to T, chromosome 14 at 70,566,176 bp
  • G to T, chromosome 15 at 34,399,091 bp
  • A to G, chromosome 15 at 81,499,277 bp
  • G to A, chromosome 15 at 98,340,365 bp
  • A to G, chromosome 16 at 35,719,429 bp
  • T to C, chromosome 16 at 89,169,542 bp
  • A to G, chromosome 17 at 46,687,894 bp
  • G to A, chromosome 18 at 47,249,263 bp
  • A to G, chromosome 18 at 80,128,264 bp
  • A to G, chromosome 19 at 4,897,326 bp
  • G to T, chromosome 19 at 5,873,368 bp
  • A to G, chromosome 19 at 12,269,156 bp
  • A to T, chromosome 19 at 42,053,045 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5717 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043337-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.