Strain Name:
C57BL/6J-MtgxR5722Btlr
Stock Number:
043340-MU
Citation ID:
RRID:MMRRC_043340-MU
Other Names:
R5722 (G1)
Major Collection:

Gene Information

Sp4
Name: trans-acting transcription factor 4
Synonyms: 5730497N03Rik, HF1-b, HF-1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20688
VEGA: 12
Homologene: 2341
Axin1
Name: axin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12005
HGNC: HGNC:903
Homologene: 2614
Kat8
Name: K(lysine) acetyltransferase 8
Synonyms: D7Ertd629e, Myst1, MOF, 5830450F21Rik, 2010203C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67773
Homologene: 41676
Arfgef1
Name: ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
Synonyms: BIG1, D130059B05Rik, D730028O18Rik, P200, ARFGEP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 211673
Homologene: 4687
Hif1a
Name: hypoxia inducible factor 1, alpha subunit
Synonyms: bHLHe78, HIF-1alpha, MOP1, HIF1alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 15251
HGNC: HGNC:4910
Homologene: 1171
Afg3l2
Name: AFG3-like AAA ATPase 2
Synonyms: par, Emv66, 2310036I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 69597
VEGA: 18
HGNC: HGNC:315
Homologene: 4947
Sv2a
Name: synaptic vesicle glycoprotein 2 a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 64051
Homologene: 32237
Hjurp
Name: Holliday junction recognition protein
Synonyms: 6430706D22Rik, A730008H23Rik, C330011F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381280
Homologene: 10184
Ighmbp2
Name: immunoglobulin mu binding protein 2
Synonyms: Smbp2, Smubp2, AEP, p110 subunit, sma, Catf1, RIPE3b1, Smbp-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20589
HGNC: HGNC:5542
Homologene: 1642
Glg1
Name: golgi apparatus protein 1
Synonyms: MG160, MG-160, Selel, CFR, CFR-1, ESL-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20340
HGNC: HGNC:4316
Homologene: 7533
Actl6a
Name: actin-like 6A
Synonyms: 2810432C06Rik, Actl6, ARP4, Baf53a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56456
Homologene: 55811
Ice1
Name: interactor of little elongation complex ELL subunit 1
Synonyms: BC018507
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218333
VEGA: 13
Homologene: 18902
Agtr1a
Name: angiotensin II receptor, type 1a
Synonyms: Agt1ar, AT1, Agtr-1a, AT1a, Agtr1a, 1810074K20Rik, Angtr-1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11607
HGNC: HGNC:336
Homologene: 3556
Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Synonyms: mtrp6, Trrp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22068
VEGA: 9
Homologene: 37944
Ttn
Name: titin
Synonyms: 2310036G12Rik, mdm, 1100001C23Rik, shru, D830007G01Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, L56, connectin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Ptprq
Name: protein tyrosine phosphatase, receptor type, Q
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237523
HGNC: HGNC:9679
Homologene: 83557
Cntnap5c
Name: contactin associated protein-like 5C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 620292
VEGA: 17
Homologene: 128806
Wdr17
Name: WD repeat domain 17
Synonyms: B230207L18Rik, 3010002I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244484
Homologene: 12460
Nwd1
Name: NACHT and WD repeat domain containing 1
Synonyms: A230063L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 319555
Homologene: 72261
Snrk
Name: SNF related kinase
Synonyms: SNRK, 2010012F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20623
Homologene: 9797
Zfp790
Name: zinc finger protein 790
Synonyms: 6330581L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233056
Homologene: 51695
Pard3b
Name: par-3 family cell polarity regulator beta
Synonyms: 2010002N16Rik, PAR3B, 1810008K04Rik, PAR3L, Als2cr19, PAR3beta, 2810455B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72823
Homologene: 35389
Plppr5
Name: phospholipid phosphatase related 5
Synonyms: Lppr5, 4833424O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75769
Homologene: 25279
Rbm46
Name: RNA binding motif protein 46
Synonyms: ENSMUSG00000033882, LOC329687
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 633285
Homologene: 17016
Irf2
Name: interferon regulatory factor 2
Synonyms: 9830146E22Rik, Irf-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16363
HGNC: HGNC:6117
Homologene: 1659
Npsr1
Name: neuropeptide S receptor 1
Synonyms: Gpr154, VRR1, 9330128H10Rik, PGR14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319239
Homologene: 45515
Gm7168
Name: predicted gene 7168
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 635895
Homologene: 133217
Smgc
Name: submandibular gland protein C
Synonyms: Sfc21, 2310010P21Rik, DXImx49e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223809
4930432K21Rik
Name: RIKEN cDNA 4930432K21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74666
Homologene: 11525
Ces1d
Name: carboxylesterase 1D
Synonyms: TGH, Ces3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 104158
HGNC: HGNC:1863
Homologene: 35606
Ranbp3l
Name: RAN binding protein 3-like
Synonyms: C130037N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223332
VEGA: 15
Homologene: 35407
Stat6
Name: signal transducer and activator of transcription 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20852
Homologene: 2373
Kyat1
Name: kynurenine aminotransferase 1
Synonyms: cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase), KATI, Ccbl1, Kat1, 2010009K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70266
HGNC: HGNC:1564
Homologene: 37872
Fkbpl
Name: FK506 binding protein-like
Synonyms: WAF-1/CIP1 stabilizing protein 39, Ppiase-X, WISp39, NG7, DIR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56299
Homologene: 10529
Olfr430
Name: olfactory receptor 430
Synonyms: GA_x6K02T2P20D-21108443-21107490, MOR105-5P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258713
Homologene: 17362
Mrgpra4
Name: MAS-related GPR, member A4
Synonyms: MrgA4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 235854
Homologene: 131159
Ugt2b36
Name: UDP glucuronosyltransferase 2 family, polypeptide B36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231396
Homologene: 128251
Pik3c2b
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
Synonyms: C330011J12Rik, PI3K-C2beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240752
HGNC: HGNC:8972
Homologene: 20582
Olfr644
Name: olfactory receptor 644
Synonyms: MOR13-1, GA_x6K02T2PBJ9-6803062-6802118
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259125
Homologene: 17491
Pgap6
Name: post-glycosylphosphatidylinositol attachment to proteins 6
Synonyms: M83, Tmem8, Rxylt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 60455
Homologene: 10944
A26c3
Name: ANKRD26-like family C, member 3
Synonyms: 4930430A15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67575
Homologene: 69410
Asic2
Name: acid-sensing (proton-gated) ion channel 2
Synonyms: BNaC1a, Accn1, BNC1, Mdeg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11418
HGNC: HGNC:99
Homologene: 137202
Sra1
Name: steroid receptor RNA activator 1
Synonyms: Srap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 24068
Homologene: 11906
Ubqln3
Name: ubiquilin 3
Synonyms: 4933400K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244178
Homologene: 9700
P4ha3
Name: procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III
Synonyms: D930031A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 320452
Homologene: 27943
Setbp1
Name: SET binding protein 1
Synonyms: Seb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240427
Homologene: 9192
Cndp2
Name: CNDP dipeptidase 2 (metallopeptidase M20 family)
Synonyms: Cn2, Pep-1, 0610010E05Rik, Pep1, Dip-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 66054
VEGA: 18
Homologene: 10085
Tox3
Name: TOX high mobility group box family member 3
Synonyms: Tnrc9, 500-9, CAGF9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244579
Homologene: 18257
Sap25
Name: sin3 associated polypeptide
Synonyms: 25 kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 751865
Homologene: 104044
Thoc3
Name: THO complex 3
Synonyms: 2410044K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 73666
Homologene: 12505
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 10,138,884 bp
  • T to A, chromosome 1 at 62,440,001 bp
  • GT to GTT, chromosome 1 at 88,266,524 bp
  • G to T, chromosome 1 at 133,103,836 bp
  • G to T, chromosome 1 at 174,069,870 bp
  • C to T, chromosome 2 at 30,188,111 bp
  • T to A, chromosome 2 at 76,708,246 bp
  • T to C, chromosome 2 at 76,945,968 bp
  • T to A, chromosome 2 at 111,204,123 bp
  • G to A, chromosome 3 at 32,718,045 bp
  • A to G, chromosome 3 at 82,865,333 bp
  • G to A, chromosome 3 at 96,185,023 bp
  • A to T, chromosome 3 at 117,621,065 bp
  • C to T, chromosome 5 at 87,092,438 bp
  • A to G, chromosome 5 at 137,641,451 bp
  • C to A, chromosome 7 at 29,830,089 bp
  • T to C, chromosome 7 at 47,981,007 bp
  • A to G, chromosome 7 at 100,305,991 bp
  • T to A, chromosome 7 at 104,068,723 bp
  • G to A, chromosome 7 at 104,141,467 bp
  • G to A, chromosome 7 at 127,924,816 bp
  • A to T, chromosome 8 at 46,818,796 bp
  • C to T, chromosome 8 at 54,660,771 bp
  • G to A, chromosome 8 at 72,675,244 bp
  • A to G, chromosome 8 at 84,171,844 bp
  • A to C, chromosome 8 at 90,347,861 bp
  • G to A, chromosome 8 at 93,178,128 bp
  • T to C, chromosome 8 at 111,169,562 bp
  • A to G, chromosome 9 at 8,680,549 bp
  • C to A, chromosome 9 at 24,313,800 bp
  • T to C, chromosome 9 at 122,164,006 bp
  • A to G, chromosome 10 at 107,686,365 bp
  • A to G, chromosome 10 at 127,658,373 bp
  • A to T, chromosome 11 at 81,967,980 bp
  • T to A, chromosome 12 at 73,941,759 bp
  • T to A, chromosome 12 at 118,299,241 bp
  • A to G, chromosome 13 at 30,382,033 bp
  • G to T, chromosome 13 at 54,460,201 bp
  • T to C, chromosome 13 at 70,615,100 bp
  • A to G, chromosome 15 at 9,000,832 bp
  • T to A, chromosome 15 at 91,841,906 bp
  • T to C, chromosome 17 at 13,949,562 bp
  • CGGGG to CGGGGG, chromosome 17 at 26,120,562 bp
  • A to T, chromosome 17 at 26,182,557 bp
  • G to A, chromosome 17 at 34,645,329 bp
  • A to T, chromosome 17 at 58,313,857 bp
  • A to G, chromosome 18 at 36,674,978 bp
  • A to G, chromosome 18 at 67,440,199 bp
  • A to T, chromosome 18 at 78,856,645 bp
  • T to A, chromosome 18 at 84,668,078 bp
  • A to G, chromosome 19 at 3,279,909 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5722 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043340-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.