Strain Name:
C57BL/6J-MtgxR5752Btlr
Stock Number:
043357-MU
Citation ID:
RRID:MMRRC_043357-MU
Other Names:
R5752 (G1)
Major Collection:

Gene Information

Atrn
Name: attractin
Synonyms: Mgca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11990
HGNC: HGNC:885
Homologene: 22542
Vcan
Name: versican
Synonyms: DPEAAE, heart defect, 5430420N07Rik, hdf, PG-M, Cspg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
Sh3gl3
Name: SH3-domain GRB2-like 3
Synonyms: endophilin III, SH3P13, Sh3d2c2, Sh3d2c, EEN-B2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20408
Homologene: 37723
Ube2k
Name: ubiquitin-conjugating enzyme E2K
Synonyms: D5Ertd601e, Hip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 53323
HGNC: HGNC:4914
Homologene: 3903
Daam1
Name: dishevelled associated activator of morphogenesis 1
Synonyms: 1700066F09Rik, 2310028E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 208846
VEGA: 12
Homologene: 36635
C77080
Name: expressed sequence C77080
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 97130
Homologene: 45837
Pot1b
Name: protection of telomeres 1B
Synonyms: 2810458H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 72836
VEGA: 17
HGNC: null
Homologene: 87058
Zzz3
Name: zinc finger, ZZ domain containing 3
Synonyms: 3110065C23Rik, 6430567E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 108946
Homologene: 9182
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230895
Homologene: 15583
Naca
Name: nascent polypeptide-associated complex alpha polypeptide
Synonyms: skNAC, LOC380777
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 17938
VEGA: 10
HGNC: HGNC:7629
Homologene: 136025
Tle3
Name: transducin-like enhancer of split 3
Synonyms: Grg3a, 2610103N05Rik, Grg3b, ESG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21887
Homologene: 21059
Sdf4
Name: stromal cell derived factor 4
Synonyms: Cab45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 20318
Homologene: 32121
Ints7
Name: integrator complex subunit 7
Synonyms: 5930412E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 77065
Homologene: 9136
Dnajc13
Name: DnaJ heat shock protein family (Hsp40) member C13
Synonyms: D030002L11Rik, LOC382100, Rme8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235567
Homologene: 13574
Mef2b
Name: myocyte enhancer factor 2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 17259
HGNC: HGNC:6995
Homologene: 48381
Plcd4
Name: phospholipase C, delta 4
Synonyms: 4921507K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18802
HGNC: HGNC:9062
Homologene: 88782
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Fat2
Name: FAT atypical cadherin 2
Synonyms: Fath2, mKIAA0811, LOC245827, EMI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Col28a1
Name: collagen, type XXVIII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 213945
Homologene: 66345
F3
Name: coagulation factor III
Synonyms: TF, Cf3, tissue factor, CD142, Cf-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 14066
HGNC: HGNC:3541
Homologene: 1511
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Plcb2
Name: phospholipase C, beta 2
Synonyms: B230205M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18796
HGNC: HGNC:9055
Homologene: 20957
Asns
Name: asparagine synthetase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 27053
HGNC: HGNC:753
Homologene: 69113
Rab11fip1
Name: RAB11 family interacting protein 1 (class I)
Synonyms: 2010200K21Rik, 4833414G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 75767
Homologene: 11853
Cfap69
Name: cilia and flagella associated protein 69
Synonyms: A330021E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 207686
Homologene: 11718
Pnpla8
Name: patatin-like phospholipase domain containing 8
Synonyms: 1200006O19Rik, iPLA2 gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 67452
Homologene: 12136
Cep126
Name: centrosomal protein 126
Synonyms: AK129341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 234915
VEGA: 9
Homologene: 28313
Ttc41
Name: tetratricopeptide repeat domain 41
Synonyms: BC030307, Gnn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103220
VEGA: 10
Homologene: 52968
Megf8
Name: multiple EGF-like-domains 8
Synonyms: Egfl4, b2b1702Clo, m687Ddg, b2b288Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 269878
HGNC: HGNC:3233
Homologene: 15988
Qprt
Name: quinolinate phosphoribosyltransferase
Synonyms: nicotinate-nucleotide pyrophosphorylase, 2410027J01Rik, QPRTase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67375
HGNC: HGNC:9755
Homologene: 8623
Rin3
Name: Ras and Rab interactor 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217835
Homologene: 11748
Tgfbr3
Name: transforming growth factor, beta receptor III
Synonyms: TBRIII, 1110036H20Rik, betaglycan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 21814
Homologene: 2436
Arhgap26
Name: Rho GTPase activating protein 26
Synonyms: 4933432P15Rik, 2610010G17Rik, 1810044B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 71302
Homologene: 36349
Aldh1l2
Name: aldehyde dehydrogenase 1 family, member L2
Synonyms: D330038I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216188
Homologene: 51942
Galnt6
Name: polypeptide N-acetylgalactosaminyltransferase 6
Synonyms: GalNAc-T6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 207839
HGNC: HGNC:4128
Homologene: 5218
Sp110
Name: Sp110 nuclear body protein
Synonyms: Ifi75, Ipr1, 5031415C07Rik, 5830484A20Rik, 52kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 109032
HGNC: HGNC:5401
Homologene: 82192
Gm960
Name: predicted gene 960
Synonyms: Top6bl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 381196
VEGA: 19
Homologene: 69381
Olfr521
Name: olfactory receptor 521
Synonyms: MOR101-2, GA_x6K02T2PBJ9-2443810-2444775
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258353
HGNC: null
Homologene: 128108
Clgn
Name: calmegin
Synonyms: calnexin-t, Cln, A2/6, 4930459O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12745
HGNC: HGNC:2060
Homologene: 68392
Cyp4f37
Name: cytochrome P450, family 4, subfamily f, polypeptide 37
Synonyms: Gm9705
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 677156
VEGA: 17
HGNC: null
Homologene: 135840
Paip2b
Name: poly(A) binding protein interacting protein 2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232164
Homologene: 25798
Gm6768
Name: predicted gene 6768
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 627557
VEGA: 12
HGNC: null
Homologene: null
Tas2r134
Name: taste receptor, type 2, member 134
Synonyms: Tas2r34, T2R134
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 387511
HGNC: null
Homologene: 66001
Mrps11
Name: mitochondrial ribosomal protein S11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67994
Homologene: 32554
1700014D04Rik
Name: RIKEN cDNA 1700014D04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 102638268
Homologene: 140986
Kank3
Name: KN motif and ankyrin repeat domains 3
Synonyms: D17Ertd288e, 0610013D04Rik, Ankrd47
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 80880
Homologene: 12749
Ttll8
Name: tubulin tyrosine ligase-like family, member 8
Synonyms: 1700019P01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239591
Homologene: 52766
Entpd2
Name: ectonucleoside triphosphate diphosphohydrolase 2
Synonyms: Cd39l1, NTPDase2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12496
HGNC: HGNC:3364
Homologene: 20333
Cxcl9
Name: chemokine (C-X-C motif) ligand 9
Synonyms: Scyb9, crg-10, CMK, Mig
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17329
HGNC: HGNC:7098
Homologene: 137210
Selp
Name: selectin, platelet
Synonyms: P-selectin, CD62P, Grmp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20344
Homologene: 2260
Gm1322
Name: predicted gene 1322
Synonyms: LOC383709
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 383709
HGNC: null
Homologene: null
Hdgfrp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
A330017A19Rik
Name: RIKEN cDNA A330017A19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: null
Ensembl: null
VEGA: null
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 74,547,972 bp
  • G to C, chromosome 1 at 85,577,202 bp
  • A to T, chromosome 1 at 164,137,242 bp
  • T to A, chromosome 1 at 191,575,893 bp
  • G to A, chromosome 2 at 25,399,769 bp
  • A to G, chromosome 2 at 41,295,612 bp
  • A to G, chromosome 2 at 51,627,868 bp
  • G to A, chromosome 2 at 67,184,635 bp
  • A to T, chromosome 2 at 76,947,984 bp
  • G to T, chromosome 2 at 118,711,051 bp
  • G to T, chromosome 2 at 130,906,544 bp
  • T to A, chromosome 3 at 121,732,404 bp
  • C to A, chromosome 3 at 152,452,122 bp
  • GGTG to GGTGTG, chromosome 4 at 129,223,980 bp
  • T to C, chromosome 4 at 145,148,970 bp
  • C to T, chromosome 4 at 155,996,304 bp
  • T to C, chromosome 5 at 5,589,204 bp
  • A to G, chromosome 5 at 65,566,068 bp
  • C to A, chromosome 5 at 92,323,856 bp
  • T to C, chromosome 5 at 107,139,807 bp
  • C to T, chromosome 6 at 7,689,365 bp
  • T to G, chromosome 6 at 8,015,025 bp
  • C to T, chromosome 6 at 83,831,270 bp
  • C to T, chromosome 7 at 25,355,114 bp
  • A to G, chromosome 7 at 78,783,595 bp
  • A to C, chromosome 7 at 81,899,703 bp
  • A to G, chromosome 7 at 82,174,948 bp
  • T to C, chromosome 7 at 99,767,948 bp
  • C to T, chromosome 7 at 127,109,244 bp
  • T to C, chromosome 8 at 27,156,586 bp
  • A to G, chromosome 8 at 70,165,617 bp
  • T to A, chromosome 8 at 83,397,041 bp
  • A to C, chromosome 9 at 8,120,745 bp
  • T to A, chromosome 9 at 61,407,471 bp
  • A to C, chromosome 9 at 104,192,774 bp
  • C to A, chromosome 10 at 83,520,380 bp
  • C to T, chromosome 10 at 86,758,346 bp
  • T to A, chromosome 10 at 128,041,928 bp
  • A to T, chromosome 11 at 55,289,237 bp
  • A to G, chromosome 12 at 44,282,887 bp
  • T to C, chromosome 12 at 71,946,546 bp
  • G to A, chromosome 12 at 102,313,119 bp
  • A to G, chromosome 12 at 119,262,614 bp
  • T to C, chromosome 13 at 59,743,202 bp
  • T to C, chromosome 13 at 89,679,950 bp
  • T to C, chromosome 15 at 88,932,728 bp
  • A to T, chromosome 15 at 100,704,126 bp
  • A to T, chromosome 17 at 32,631,332 bp
  • A to G, chromosome 17 at 33,818,063 bp
  • C to A, chromosome 17 at 46,890,040 bp
  • A to T, chromosome 17 at 55,687,834 bp
  • G to A, chromosome 18 at 39,286,672 bp
  • C to A, chromosome 19 at 4,626,020 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5752 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043357-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.