Strain Name:
C57BL/6J-MtgxR5756Btlr/Mmmh
Stock Number:
043359-MU
Citation ID:
RRID:MMRRC_043359-MU
Other Names:
R5756 (G1)
Major Collection:

Gene Information

Gcm2
Name: glial cells missing homolog 2
Synonyms: Gcm1-rs2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 107889
VEGA: 13
HGNC: HGNC:4198
Homologene: 3490
Ggta1
Name: glycoprotein galactosyltransferase alpha 1, 3
Synonyms: GALT, alpha Gal, Gal, glycoprotein alpha galactosyl transferase 1, alpha3GalT, Ggta-1, Ggta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14594
HGNC: HGNC:4253
Homologene: 7730
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, C130061D10Rik, Phr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105689
Homologene: 9005
Kif13b
Name: kinesin family member 13B
Synonyms: GAKIN, N-3 kinesin, C130021D12Rik, 5330429L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16554
VEGA: 14
Homologene: 9073
Asap1
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain1
Synonyms: Ddef1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 13196
HGNC: HGNC:2720
Homologene: 7684
Vps53
Name: VPS53 GARP complex subunit
Synonyms: 2310040I21Rik, 2010002A08Rik, 3100002B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68299
Homologene: 6264
Pde7a
Name: phosphodiesterase 7A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18583
HGNC: HGNC:8791
Homologene: 1956
Coro7
Name: coronin 7
Synonyms: 0610011B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 78885
Homologene: 11573
Eif2ak4
Name: eukaryotic translation initiation factor 2 alpha kinase 4
Synonyms: GCN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27103
Homologene: 40891
Fnta
Name: farnesyltransferase, CAAX box, alpha
Synonyms: FTA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14272
HGNC: HGNC:3782
Homologene: 1534
Usp24
Name: ubiquitin specific peptidase 24
Synonyms: 2810030C21Rik, 2700066K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329908
Homologene: 35420
Lars2
Name: leucyl-tRNA synthetase, mitochondrial
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102436
VEGA: 9
Homologene: 6526
Tep1
Name: telomerase associated protein 1
Synonyms: Tp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21745
VEGA: 14
Homologene: 5157
Polr3c
Name: polymerase (RNA) III (DNA directed) polypeptide C
Synonyms: RPC62, RPC3, 4933407E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74414
Homologene: 38185
Dusp11
Name: dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
Synonyms: 2010300F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 72102
HGNC: HGNC:3066
Homologene: 31183
Gprc5c
Name: G protein-coupled receptor, family C, group 5, member C
Synonyms: 1110028I06Rik, 3200002M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70355
Homologene: 11099
Pisd
Name: phosphatidylserine decarboxylase
Synonyms: 9030221M09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320951
HGNC: HGNC:8999
Homologene: 81653
Cables1
Name: CDK5 and Abl enzyme substrate 1
Synonyms: interactor-1 with cdk3, ik3-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 63955
VEGA: 18
Homologene: 11097
Lrrc55
Name: leucine rich repeat containing 55
Synonyms: LOC241528, A330097E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241528
VEGA: 2
Homologene: 19385
Calcoco1
Name: calcium binding and coiled coil domain 1
Synonyms: 1810009B06Rik, CoCoA, Gcap11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67488
Homologene: 10845
Itln1
Name: intelectin 1 (galactofuranose binding)
Synonyms: IntL, Itln2, mLfR, Itlna
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16429
Homologene: 111044
Zfp81
Name: zinc finger protein 81
Synonyms: KRAB13, Zfp78, Hszfp36, C330034P10Rik, D330034E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224694
Homologene: 138633
Ibtk
Name: inhibitor of Bruton agammaglobulinemia tyrosine kinase
Synonyms: 5430411K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 108837
Homologene: 34661
Zfyve26
Name: zinc finger, FYVE domain containing 26
Synonyms: 9330197E15Rik, LOC380767, A630028O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 211978
VEGA: 12
Homologene: 9102
Tarsl2
Name: threonyl-tRNA synthetase-like 2
Synonyms: A530046H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 272396
Homologene: 65036
Tnfrsf19
Name: tumor necrosis factor receptor superfamily, member 19
Synonyms: TAJ, Troy, TAJ-ALPHA, TRADE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 29820
VEGA: 14
Homologene: 8481
Fgf3
Name: fibroblast growth factor 3
Synonyms: Int-P, Int-2, Fgf-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14174
HGNC: HGNC:3681
Homologene: 3841
Tex15
Name: testis expressed gene 15
Synonyms: 2210014E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 104271
Homologene: 12837
Tbx15
Name: T-box 15
Synonyms: Tbx8, de, Tbx14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 21384
Homologene: 7967
Astn2
Name: astrotactin 2
Synonyms: 1d8, Astnl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56079
Homologene: 77850
Hrc
Name: histidine rich calcium binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15464
HGNC: HGNC:5178
Homologene: 137234
Usp40
Name: ubiquitin specific peptidase 40
Synonyms: B230215L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227334
Homologene: 32400
Xylt1
Name: xylosyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233781
Homologene: 32534
Olfr921
Name: olfactory receptor 921
Synonyms: GA_x6K02T2PVTD-32478047-32478988, MOR165-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258778
VEGA: 9
Homologene: 128138
Slc4a11
Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269356
Homologene: 12931
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75777
Homologene: 44907
Elapor2
Name: endosome-lysosome associated apoptosis and autophagy regulator family member 2
Synonyms: 9330182L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231014
Homologene: 27396
Myo1c
Name: myosin IC
Synonyms: myosin-Ibeta, myr2, C80397, mm1beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17913
HGNC: HGNC:7597
Homologene: 32046
Gm16432
Name: predicted gene 16432
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Ift140
Name: intraflagellar transport 140
Synonyms: Wdtc2, Tce5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106633
Homologene: 40979
Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Synonyms: Cav2.3, Cchra1, alpha1E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12290
HGNC: HGNC:1392
Homologene: 20185
Sart1
Name: squamous cell carcinoma antigen recognized by T cells 1
Synonyms: U5-110K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20227
VEGA: 19
Homologene: 133770
Smarca5
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Synonyms: Snf2h, D330027N15Rik, 4933427E24Rik, D030040M08Rik, MommeD4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 93762
Homologene: 55764
Phyhip
Name: phytanoyl-CoA hydroxylase interacting protein
Synonyms: PAHX-AP#1, PAHX-AP1, C630010D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105653
Homologene: 8847
Olfr765
Name: olfactory receptor 765
Synonyms: GA_x6K02T2PULF-10732607-10731678, MOR115-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 544748
Homologene: 105186
Etfdh
Name: electron transferring flavoprotein, dehydrogenase
Synonyms: 0610010I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66841
HGNC: HGNC:3483
Homologene: 3275
Sv2c
Name: synaptic vesicle glycoprotein 2c
Synonyms: 4930527L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75209
Homologene: 57152
Dgki
Name: diacylglycerol kinase, iota
Synonyms: C130010K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320127
HGNC: HGNC:2855
Homologene: 37956
Sh3rf3
Name: SH3 domain containing ring finger 3
Synonyms: 4831416G18Rik, Sh3md4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237353
Homologene: 77551
Tnnt3
Olfr640
Name: olfactory receptor 640
Synonyms: GA_x6K02T2PBJ9-6756759-6755815, MOR13-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258819
Homologene: 17404
Ffar4
Name: free fatty acid receptor 4
Synonyms: Gpr120, Pgr4, Gpr129, O3far1, Ffa4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107221
VEGA: 19
Homologene: 18769
4930579C12Rik
Name: RIKEN cDNA 4930579C12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319213
Ggt5
Name: gamma-glutamyltransferase 5
Synonyms: GGT-REL, GGL, gamma-glutamyl leukotrienase, Ggtla1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 23887
HGNC: HGNC:4260
Homologene: 55802
Bmp5
Name: bone morphogenetic protein 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12160
HGNC: HGNC:1072
Homologene: 22412
Aqp6
Name: aquaporin 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11831
VEGA: 15
HGNC: HGNC:639
Homologene: 20399
Gm5454
Name: predicted gene 5454
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 432800
VEGA: 13
Slc6a16
Name: solute carrier family 6, member 16
Synonyms: LOC381884
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381884
Homologene: 49366
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 87,951,691 bp
  • A to G, chromosome 1 at 154,471,637 bp
  • A to G, chromosome 1 at 171,516,917 bp
  • A to T, chromosome 1 at 178,116,227 bp
  • T to C, chromosome 2 at 35,402,383 bp
  • G to A, chromosome 2 at 85,196,383 bp
  • T to C, chromosome 2 at 118,462,740 bp
  • G to T, chromosome 2 at 130,687,863 bp
  • A to G, chromosome 3 at 19,264,845 bp
  • T to C, chromosome 3 at 79,613,756 bp
  • T to C, chromosome 3 at 96,714,134 bp
  • A to T, chromosome 3 at 99,313,086 bp
  • G to A, chromosome 4 at 66,119,188 bp
  • T to A, chromosome 4 at 106,362,483 bp
  • A to C, chromosome 5 at 9,462,995 bp
  • G to A, chromosome 5 at 32,738,498 bp
  • C to T, chromosome 6 at 36,937,058 bp
  • T to C, chromosome 6 at 85,952,357 bp
  • A to T, chromosome 7 at 45,260,850 bp
  • T to C, chromosome 7 at 45,336,706 bp
  • A to G, chromosome 7 at 65,675,976 bp
  • T to C, chromosome 7 at 104,021,682 bp
  • C to T, chromosome 7 at 117,650,700 bp
  • G to A, chromosome 7 at 142,502,758 bp
  • G to A, chromosome 7 at 144,842,951 bp
  • A to T, chromosome 8 at 26,009,707 bp
  • G to A, chromosome 8 at 33,575,833 bp
  • A to C, chromosome 8 at 80,710,604 bp
  • T to A, chromosome 9 at 38,775,258 bp
  • A to G, chromosome 9 at 75,776,367 bp
  • C to G, chromosome 9 at 85,731,254 bp
  • A to G, chromosome 9 at 89,128,866 bp
  • T to C, chromosome 9 at 123,438,199 bp
  • T to C, chromosome 10 at 59,104,382 bp
  • A to T, chromosome 10 at 75,604,773 bp
  • A to G, chromosome 10 at 129,046,226 bp
  • T to G, chromosome 11 at 75,658,414 bp
  • A to T, chromosome 11 at 76,092,330 bp
  • G to T, chromosome 11 at 114,864,267 bp
  • T to A, chromosome 12 at 79,264,357 bp
  • G to A, chromosome 13 at 41,109,896 bp
  • T to C, chromosome 13 at 95,985,967 bp
  • A to G, chromosome 13 at 103,356,347 bp
  • C to T, chromosome 14 at 50,837,379 bp
  • A to G, chromosome 14 at 61,024,775 bp
  • T to C, chromosome 14 at 64,736,305 bp
  • T to G, chromosome 14 at 70,467,092 bp
  • A to T, chromosome 14 at 103,133,974 bp
  • G to T, chromosome 15 at 10,551,550 bp
  • A to T, chromosome 15 at 64,167,707 bp
  • A to T, chromosome 15 at 99,602,742 bp
  • T to C, chromosome 15 at 102,719,651 bp
  • C to T, chromosome 16 at 4,632,284 bp
  • A to G, chromosome 17 at 25,028,813 bp
  • A to C, chromosome 17 at 33,334,333 bp
  • A to G, chromosome 18 at 11,941,353 bp
  • T to C, chromosome 19 at 5,380,469 bp
  • C to T, chromosome 19 at 38,113,958 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5756 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043359-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.