Strain Name:
C57BL/6J-MtgxR5761Btlr
Stock Number:
043363-MU
Citation ID:
RRID:MMRRC_043363-MU
Other Names:
R5761 (G1)
Major Collection:

Gene Information

Vangl2
Name: VANGL planar cell polarity 2
Synonyms: Lpp1, C530001F03Rik, skam17Jus, Ltap, strabismus, loop-tail, ska17, Lootl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 93840
Homologene: 62161
Foxq1
Name: forkhead box Q1
Synonyms: HFH-1, Hfh1l, Hfh1, sa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 15220
Homologene: 7359
Map2k6
Name: mitogen-activated protein kinase kinase 6
Synonyms: MAP kinase kinase 6, MKK6, SAPKK3, Prkmk6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 26399
HGNC: HGNC:6846
Homologene: 55686
Kif2a
Name: kinesin family member 2A
Synonyms: Kns2, Kif2, M-kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16563
HGNC: HGNC:6318
Homologene: 3320
Igf1r
Name: insulin-like growth factor I receptor
Synonyms: CD221, IGF-1R, line 186, hyft, A330103N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16001
HGNC: HGNC:5465
Homologene: 30997
Aebp2
Name: AE binding protein 2
Synonyms: B230313N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11569
Homologene: 40690
Ccz1
Name: CCZ1 vacuolar protein trafficking and biogenesis associated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231874
Homologene: 56717
Cep104
Name: centrosomal protein 104
Synonyms: BC046331
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230967
Homologene: 44919
Baz2a
Name: bromodomain adjacent to zinc finger domain, 2A
Synonyms: Tip5, Walp3, C030005G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 116848
VEGA: 10
HGNC: HGNC:962
Homologene: 8393
Mtrex
Name: Mtr4 exosome RNA helicase
Synonyms: 2610528A15Rik, Skiv2l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72198
VEGA: 13
Homologene: 6257
Abcb8
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 8
Synonyms: 4833412N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74610
HGNC: HGNC:49
Homologene: 5203
Ecpas
Name: Ecm29 proteasome adaptor and scaffold
Synonyms: AI314180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230249
Homologene: 6056
Ccdc187
Name: coiled-coil domain containing 187
Synonyms: 4932418E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329366
Homologene: 77630
Gpr89
Name: G protein-coupled receptor 89
Synonyms: SH120, 4933412D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67549
Homologene: 9475
Igf2r
Name: insulin-like growth factor 2 receptor
Synonyms: Mpr300, CI-MPR, IGF-II/CI-MPR, M6P/IGF2R, CD222, mannose-6-phosphate receptor, cation independent
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16004
HGNC: HGNC:5467
Homologene: 676
Crmp1
Name: collapsin response mediator protein 1
Synonyms: Ulip3, DRP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12933
HGNC: HGNC:2365
Homologene: 20347
Lap3
Name: leucine aminopeptidase 3
Synonyms: Pep-S, Pep-7, LAP, peptidase S, Pep7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66988
Homologene: 41072
Cmc1
Name: COX assembly mitochondrial protein 1
Synonyms: 2010312P05Rik, 2010110K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67899
VEGA: 9
Homologene: 12207
Chd6
Name: chromodomain helicase DNA binding protein 6
Synonyms: 6330406J24Rik, 5430439G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71389
Homologene: 32772
Ddhd2
Name: DDHD domain containing 2
Synonyms: SAMWD1, 2010305K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72108
Homologene: 66646
Akap8
Name: A kinase (PRKA) anchor protein 8
Synonyms: AKAP95, 1200016A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56399
VEGA: 17
HGNC: HGNC:378
Homologene: 4278
Ythdc1
Name: YTH domain containing 1
Synonyms: A730098D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231386
Homologene: 15796
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171395
Homologene: 51376
Tlr3
Name: toll-like receptor 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 142980
Homologene: 20696
Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Synonyms: Cox-2, cyclooxygenase 2, Pghs2, COX2, prostaglandin G/H synthase, PHS-2, cyclooxygenase-2, PGHS-2, Tis10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19225
HGNC: HGNC:9605
Homologene: 31000
Zmiz1
Name: zinc finger, MIZ-type containing 1
Synonyms: Rai17, Zimp10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 328365
Homologene: 10667
Cyp4f18
Name: cytochrome P450, family 4, subfamily f, polypeptide 18
Synonyms: 1810054N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72054
HGNC: HGNC:2646
Homologene: 128623
Hjv
Name: hemojuvelin BMP co-receptor
Synonyms: 2310035L15Rik, 5230400G09Rik, DL-M, Rgmc, HJV, hemojuvelin, Hfe2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69585
HGNC: HGNC:4887
Homologene: 17060
Col4a3
Name: collagen, type IV, alpha 3
Synonyms: alpha3(IV), tumstatin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12828
HGNC: HGNC:2204
Homologene: 68033
Bud13
Name: BUD13 homolog
Synonyms: D030060M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 215051
Homologene: 13102
Ncoa6
Name: nuclear receptor coactivator 6
Synonyms: PRIP, ASC2, RAP250, AIB3, NRC, ASC-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56406
Homologene: 137337
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: A530024P18Rik, 2310008C07Rik, 2310003D02Rik, mXin beta, myomaxin, Cmya3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241431
Homologene: 19388
Hrc
Name: histidine rich calcium binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15464
HGNC: HGNC:5178
Homologene: 137234
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: MyHC-IId/x, Myhs-f, Myhs-f2, Myhsf2, MYHC-IIX, myosin heavy chain 2X, IId, IId/x, A530084A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Usp35
Name: ubiquitin specific peptidase 35
Synonyms: LOC244144, LOC381901
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244144
Homologene: 35459
St6gal1
Name: beta galactoside alpha 2,6 sialyltransferase 1
Synonyms: ST6Gal I, St6Gal-I, Siat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20440
Homologene: 2281
Abca6
Name: ATP-binding cassette, sub-family A (ABC1), member 6
Synonyms: 6330565N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76184
HGNC: HGNC:36
Homologene: 71264
Acad12
Name: acyl-Coenzyme A dehydrogenase family, member 12
Synonyms: 9330129D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 338350
Adam2
Name: a disintegrin and metallopeptidase domain 2
Synonyms: Ph30-beta, Ftnb, fertilin beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 11495
VEGA: 14
HGNC: HGNC:198
Homologene: 1127
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: B830017A01Rik, 3110047P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319807
Homologene: 14974
Cntnap5b
Name: contactin associated protein-like 5B
Synonyms: Caspr5-2, C230078M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241175
Homologene: 104295
Spty2d1
Name: SPT2 chromatin protein domain containing 1
Synonyms: 5830435K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101685
Homologene: 45499
Aldh1a3
Name: aldehyde dehydrogenase family 1, subfamily A3
Synonyms: ALDH6, V1, retinaldehyde dehydrogenase 3, RALDH3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56847
HGNC: HGNC:409
Homologene: 68080
Itga2b
Name: integrin alpha 2b
Synonyms: platelet glycoprotein IIb, GpIIb, alphaIIb, CD41, GP IIb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16399
HGNC: HGNC:6138
Homologene: 37304
Vmn1r19
Name: vomeronasal 1 receptor 19
Synonyms: V1rc27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171200
Homologene: 134034
Cyp3a16
Name: cytochrome P450, family 3, subfamily a, polypeptide 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13114
Homologene: 133568
Tmem171
Name: transmembrane protein 171
Synonyms: LOC380863
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 380863
Homologene: 18301
Or3a1b
Name: olfactory receptor family 3 subfamily A member 1B
Synonyms: GA_x6K02T2P1NL-4278037-4278984, MOR255-6, Olfr401
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258701
HGNC: HGNC:8282
Homologene: 73922
Vmn2r23
Name: vomeronasal 2, receptor 23
Synonyms: EG435916
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 435916
Homologene: 135826
Gm10428
Name: predicted gene 10428
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Nom1
Name: nucleolar protein with MIF4G domain 1
Synonyms: LOC381627, D5Kng1, Gm1040
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 433864
Homologene: 39776
Zbtb39
Name: zinc finger and BTB domain containing 39
Synonyms: 7030401O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 320080
VEGA: 10
Homologene: 8890
Vmn2r-ps69
Name: vomeronasal 2, receptor, pseudogene 69
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 670926
Cybb
Name: cytochrome b-245, beta polypeptide
Synonyms: gp91phox, gp91phox, Nox2, Cgd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 13058
HGNC: HGNC:2578
Homologene: 68054
Vmn1r175
Name: vomeronasal 1 receptor 175
Synonyms: Gm6299
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 622222
Homologene: 128341
Cbarp
Name: calcium channel, voltage-dependent, beta subunit associated regulatory protein
Synonyms: R29144/1, Dos
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100503659
Homologene: 82309
Or51a24
Name: olfactory receptor family 51 subfamily A member 24
Synonyms: GA_x6K02T2PBJ9-6819097-6818150, MOR13-5, Olfr645
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258247
Homologene: 66155
Qsox1
Name: quiescin Q6 sulfhydryl oxidase 1
Synonyms: 1300003H02Rik, Qscn6, QSOX, b2b2673Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 104009
HGNC: HGNC:9756
Homologene: 37690
Sult2a6
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6
Synonyms: Gm6957
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 629219
Homologene: 37741
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 82,716,057 bp
  • T to C, chromosome 1 at 100,446,894 bp
  • A to G, chromosome 1 at 150,105,528 bp
  • T to A, chromosome 1 at 155,779,528 bp
  • T to A, chromosome 1 at 172,006,127 bp
  • G to A, chromosome 2 at 26,276,092 bp
  • A to G, chromosome 2 at 67,510,967 bp
  • A to G, chromosome 2 at 155,408,141 bp
  • C to A, chromosome 2 at 160,957,078 bp
  • C to T, chromosome 2 at 160,957,079 bp
  • T to C, chromosome 3 at 96,528,622 bp
  • A to G, chromosome 3 at 96,892,880 bp
  • T to C, chromosome 4 at 58,853,131 bp
  • T to C, chromosome 4 at 153,981,224 bp
  • T to C, chromosome 5 at 24,405,881 bp
  • A to G, chromosome 5 at 29,437,641 bp
  • A to G, chromosome 5 at 37,282,868 bp
  • A to C, chromosome 5 at 45,504,805 bp
  • A to T, chromosome 5 at 63,725,230 bp
  • A to G, chromosome 5 at 86,835,951 bp
  • A to T, chromosome 5 at 121,604,180 bp
  • C to T, chromosome 5 at 143,992,510 bp
  • A to G, chromosome 5 at 145,442,033 bp
  • A to T, chromosome 6 at 57,405,353 bp
  • C to A, chromosome 6 at 123,712,759 bp
  • T to C, chromosome 6 at 140,624,217 bp
  • T to C, chromosome 7 at 14,250,358 bp
  • A to C, chromosome 7 at 23,808,480 bp
  • A to T, chromosome 7 at 45,336,601 bp
  • A to G, chromosome 7 at 46,998,284 bp
  • C to A, chromosome 7 at 66,419,179 bp
  • T to A, chromosome 7 at 68,207,253 bp
  • T to A, chromosome 7 at 85,304,015 bp
  • C to T, chromosome 7 at 97,312,351 bp
  • G to A, chromosome 7 at 104,084,169 bp
  • A to G, chromosome 8 at 25,741,699 bp
  • G to A, chromosome 8 at 45,402,771 bp
  • T to A, chromosome 8 at 71,996,131 bp
  • C to T, chromosome 9 at 46,288,052 bp
  • T to C, chromosome 9 at 118,115,375 bp
  • CGCCTCTGCTGCCTCT to CGCCTCT, chromosome 10 at 80,132,233 bp
  • C to T, chromosome 10 at 127,742,646 bp
  • A to G, chromosome 10 at 128,119,690 bp
  • A to G, chromosome 11 at 8,916,301 bp
  • G to T, chromosome 11 at 62,753,343 bp
  • A to G, chromosome 11 at 67,219,252 bp
  • T to A, chromosome 11 at 74,121,509 bp
  • A to G, chromosome 11 at 102,466,274 bp
  • A to T, chromosome 11 at 110,210,101 bp
  • T to G, chromosome 11 at 110,399,371 bp
  • G to A, chromosome 13 at 31,559,331 bp
  • A to G, chromosome 13 at 98,692,511 bp
  • T to A, chromosome 13 at 106,962,164 bp
  • T to A, chromosome 13 at 112,917,662 bp
  • T to A, chromosome 14 at 25,651,304 bp
  • C to A, chromosome 14 at 25,651,306 bp
  • A to T, chromosome 14 at 66,046,146 bp
  • T to G, chromosome 16 at 23,321,055 bp
  • A to C, chromosome 17 at 12,698,352 bp
  • A to T, chromosome 17 at 32,317,185 bp
  • C to G, chromosome X at 9,450,750 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5761 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043363-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.