Strain Name:
C57BL/6J-MtgxR5763Btlr
Stock Number:
043364-MU
Citation ID:
RRID:MMRRC_043364-MU
Other Names:
R5763 (G1)
Major Collection:

Gene Information

Suz12
Name: SUZ12 polycomb repressive complex 2 subunit
Synonyms: D11Ertd530e, 2610028O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 52615
Homologene: 32256
Tnpo1
Name: transportin 1
Synonyms: D13Ertd688e, Kpnb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238799
HGNC: HGNC:6401
Homologene: 5358
Foxm1
Name: forkhead box M1
Synonyms: HFH-11B, Foxm1b, WIN, Fkh16, Mpm2, Trident
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14235
HGNC: HGNC:3818
Homologene: 7318
Nrxn2
Name: neurexin II
Synonyms: neurexin II beta, neurexin II alpha, 6430591O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18190
HGNC: HGNC:8009
Homologene: 86984
Tet1
Name: tet methylcytosine dioxygenase 1
Synonyms: Cxxc6, BB001228, 2510010B09Rik, D10Ertd17e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 52463
Homologene: 12735
Ubap2
Name: ubiquitin-associated protein 2
Synonyms: 1190005K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68926
Homologene: 73649
Crybg3
Name: beta-gamma crystallin domain containing 3
Synonyms: Gm9581
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224273
Homologene: 28544
Srsf11
Name: serine and arginine-rich splicing factor 11
Synonyms: 2610019N13Rik, 0610009J05Rik, Sfrs11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69207
Homologene: 36164
Setd2
Name: SET domain containing 2
Synonyms: 4921524K10Rik, KMT3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235626
Homologene: 56493
Rheb
Name: Ras homolog enriched in brain
Synonyms: Rheb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19744
Homologene: 123916
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
Brwd1
Name: bromodomain and WD repeat domain containing 1
Synonyms: repro5, Wdr9, D530019K20Rik, 5330419I02Rik, G1-403-16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 93871
Homologene: 23130
Gabpa
Name: GA repeat binding protein, alpha
Synonyms: GABPalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 14390
HGNC: HGNC:4071
Homologene: 1543
Zik1
Name: zinc finger protein interacting with K protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22775
Homologene: 32076
Dhx16
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 16
Synonyms: 2410006N22Rik, Ddx16, DBP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 69192
HGNC: HGNC:2739
Homologene: 2658
Son
Name: Son DNA binding protein
Synonyms: 2900011L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20658
Homologene: 10551
Nog
Name: noggin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18121
HGNC: HGNC:7866
Homologene: 3979
Podxl2
Name: podocalyxin-like 2
Synonyms: D130074J02Rik, Endoglycan, PODLX2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 319655
Homologene: 9254
Brca2
Name: breast cancer 2, early onset
Synonyms: RAB163, Fancd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12190
HGNC: HGNC:1101
Homologene: 41
Ddx24
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
Synonyms: 2510027P10Rik, 1700055J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 27225
VEGA: 12
Homologene: 10702
Siglecf
Name: sialic acid binding Ig-like lectin F
Synonyms: Siglec5, mSiglec-F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233186
Homologene: 50482
Col1a2
Name: collagen, type I, alpha 2
Synonyms: Cola2, Cola-2, Col1a-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12843
HGNC: HGNC:2198
Homologene: 69
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1154Clo, b2b1537Clo, Dnahc5, b2b3491Clo, b2b1565Clo, Mdnah5, b2b1134Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Ces2a
Name: carboxylesterase 2A
Synonyms: 9130231C15Rik, Ces6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102022
HGNC: HGNC:1864
Homologene: 136396
Pik3r4
Name: phosphoinositide-3-kinase regulatory subunit 4
Synonyms: p150, Vps15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75669
HGNC: HGNC:8982
Homologene: 24678
Agl
Name: amylo-1,6-glucosidase, 4-alpha-glucanotransferase
Synonyms: 1110061O17Rik, 9430004C13Rik, 9630046L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77559
HGNC: HGNC:321
Homologene: 536
Astn2
Name: astrotactin 2
Synonyms: Astnl, 1d8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56079
Homologene: 77850
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: Dnahc9, D11Ertd686e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Gm884
Name: predicted gene 884
Synonyms: LOC380730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380730
Homologene: 134511
Adamts7
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
Synonyms: ADAM-TS7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 108153
HGNC: HGNC:223
Homologene: 22803
Camk2g
Name: calcium/calmodulin-dependent protein kinase II gamma
Synonyms: 5930429P18Rik, Camkg, CaMK II, Ca2+/calmodulin-dependent protein kinase II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12325
VEGA: 14
HGNC: HGNC:1463
Homologene: 15596
Entpd7
Name: ectonucleoside triphosphate diphosphohydrolase 7
Synonyms: LALP1, 1810020C02Rik, Lysal2, 1810012B13Rik, 2810003F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 93685
Homologene: 122202
Ankrd60
Name: ankyrin repeat domain 60
Synonyms: 1700019A24Rik, 1700030G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70065
Homologene: 43792
Snx15
Name: sorting nexin 15
Synonyms: 1500032B08Rik, E130013C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 69024
Homologene: 12294
Rsph4a
Name: radial spoke head 4 homolog A (Chlamydomonas)
Synonyms: Rshl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 212892
Homologene: 71779
Micalcl
Name: MICAL C-terminal like
Synonyms: Ebitein1, 4921517J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100504195
Homologene: 13149
Masp1
Name: mannan-binding lectin serine peptidase 1
Synonyms: Crarf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17174
VEGA: 16
HGNC: HGNC:6901
Homologene: 88793
Col11a1
Name: collagen, type XI, alpha 1
Synonyms: C530001D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12814
HGNC: HGNC:2186
Homologene: 56389
Gmip
Name: Gem-interacting protein
Synonyms: 5031419I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 78816
Homologene: 9570
Actl6b
Name: actin-like 6B
Synonyms: Actl6, Baf53b, ArpNa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 83766
HGNC: HGNC:160
Homologene: 81844
Rhoj
Name: ras homolog family member J
Synonyms: TCL, 1110005O19Rik, TC10L, Arhj
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 80837
HGNC: HGNC:688
Homologene: 56894
Tmc6
Name: transmembrane channel-like gene family 6
Synonyms: D11Ertd204e, EVER1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217353
Homologene: 5258
Adam22
Name: a disintegrin and metallopeptidase domain 22
Synonyms: MDC2, 2900022I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11496
HGNC: HGNC:201
Homologene: 37898
Cttnbp2
Name: cortactin binding protein 2
Synonyms: 9130022E09Rik, 3010022N24Rik, ORF4, 4732477G22Rik, Cortbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 30785
Homologene: 14125
Vmn2r52
Name: vomeronasal 2, receptor 52
Synonyms: EG384534
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 384534
Homologene: 129605
Olfr746
Name: olfactory receptor 746
Synonyms: GA_x6K02T2PMLR-6372116-6373060, MOR106-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258295
Homologene: 134081
Herc6
Name: hect domain and RLD 6
Synonyms: 2510038N07Rik, 4930427L17Rik, 1700121D12Rik, CEB1, Herc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67138
Homologene: 70768
Acot11
Name: acyl-CoA thioesterase 11
Synonyms: 2010309H15Rik, Thea, Them1, 1110020M10Rik, BFIT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329910
Homologene: 11977
Phyhd1
Name: phytanoyl-CoA dioxygenase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227696
Homologene: 14939
Vmn2r14
Name: vomeronasal 2, receptor 14
Synonyms: EG231591
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231591
Homologene: 129606
AA986860
Name: expressed sequence AA986860
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 212439
Homologene: 49741
Prss50
Name: protease, serine 50
Synonyms: Tsp50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235631
Homologene: 8314
Olfr393
Name: olfactory receptor 393
Synonyms: MOR135-7, GA_x6K02T2P1NL-4004140-4003208
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259010
Homologene: 79335
Mill1
Name: MHC I like leukocyte 1
Synonyms: 5530400I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 266815
Homologene: 105329
Ldha
Name: lactate dehydrogenase A
Synonyms: lactate dehydrogenase-A, l7R2, LDH-A, Ldh1, Ldh-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16828
HGNC: HGNC:6535
Homologene: 56495
Olfr530
Name: olfactory receptor 530
Synonyms: GA_x6K02T2PBJ9-42523824-42522901, MOR252-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258512
Homologene: 128384
Zfp663
Name: zinc finger protein 663
Synonyms: Gm1008, LOC381405
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381405
Homologene: 128277
Mrgpra3
Name: MAS-related GPR, member A3
Synonyms: G protein-coupled receptor, MrgA3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233222
Homologene: 131159
Gipr
Name: gastric inhibitory polypeptide receptor
Synonyms: LOC381853, LOC232937, glucose-dependent insulinotropic polypeptide receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381853
HGNC: HGNC:4271
Homologene: 20081
Slc14a1
Name: solute carrier family 14 (urea transporter), member 1
Synonyms: UT-B, 2610507K20Rik, 3021401A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 108052
Homologene: 9285
Qsox1
Name: quiescin Q6 sulfhydryl oxidase 1
Synonyms: Qscn6, QSOX, b2b2673Clo, 1300003H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 104009
HGNC: HGNC:9756
Homologene: 37690
Olfr1252
Name: olfactory receptor 1252
Synonyms: GA_x6K02T2Q125-51162884-51161940, MOR231-22_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 404331
Homologene: 128094
Fam221a
Name: family with sequence similarity 221, member A
Synonyms: D330028D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 231946
Homologene: 18214
Pnma1
Name: paraneoplastic antigen MA1
Synonyms: 5730402C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 70481
HGNC: HGNC:9158
Homologene: 4399
Olfr367-ps
Name: olfactory receptor 367, pseudogene
Synonyms: EG545417, MOR128-1, GA_x6K02T2NLDC-33954853-33955794
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 545417
Homologene: 129598
Trav4-3
Name: T cell receptor alpha variable 4-3
Synonyms: Gm17002
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100126471
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 130,743,031 bp
  • A to G, chromosome 1 at 155,779,879 bp
  • T to A, chromosome 2 at 30,279,971 bp
  • T to C, chromosome 2 at 37,271,013 bp
  • T to A, chromosome 2 at 89,722,028 bp
  • G to T, chromosome 2 at 165,358,435 bp
  • TGGCCACGCGG to TGG, chromosome 2 at 173,578,089 bp
  • T to C, chromosome 3 at 114,094,596 bp
  • A to T, chromosome 3 at 116,753,360 bp
  • C to T, chromosome 3 at 158,023,344 bp
  • T to C, chromosome 4 at 41,195,809 bp
  • T to A, chromosome 4 at 65,729,331 bp
  • C to T, chromosome 4 at 106,760,130 bp
  • A to T, chromosome 5 at 8,134,544 bp
  • A to G, chromosome 5 at 24,807,787 bp
  • T to C, chromosome 5 at 109,215,858 bp
  • T to A, chromosome 5 at 137,566,801 bp
  • T to C, chromosome 5 at 150,548,006 bp
  • T to A, chromosome 6 at 4,515,682 bp
  • T to C, chromosome 6 at 18,414,299 bp
  • T to G, chromosome 6 at 49,378,584 bp
  • T to A, chromosome 6 at 57,662,887 bp
  • T to C, chromosome 6 at 88,849,823 bp
  • T to A, chromosome 6 at 128,366,108 bp
  • T to A, chromosome 7 at 10,171,304 bp
  • G to T, chromosome 7 at 10,492,366 bp
  • T to A, chromosome 7 at 18,245,662 bp
  • T to A, chromosome 7 at 19,163,550 bp
  • A to T, chromosome 7 at 43,356,320 bp
  • G to A, chromosome 7 at 46,847,789 bp
  • A to T, chromosome 7 at 47,589,607 bp
  • G to A, chromosome 7 at 112,374,654 bp
  • T to A, chromosome 7 at 140,373,655 bp
  • A to G, chromosome 8 at 69,817,851 bp
  • C to T, chromosome 8 at 104,736,124 bp
  • T to A, chromosome 9 at 90,188,409 bp
  • A to G, chromosome 9 at 95,945,123 bp
  • G to T, chromosome 9 at 105,669,775 bp
  • T to G, chromosome 9 at 110,556,275 bp
  • A to T, chromosome 9 at 110,862,449 bp
  • A to T, chromosome 10 at 33,905,688 bp
  • T to A, chromosome 10 at 62,840,068 bp
  • C to A, chromosome 11 at 65,955,239 bp
  • T to A, chromosome 11 at 73,847,867 bp
  • C to A, chromosome 11 at 80,025,308 bp
  • C to T, chromosome 11 at 89,301,465 bp
  • G to A, chromosome 11 at 103,613,643 bp
  • A to G, chromosome 11 at 117,769,433 bp
  • A to G, chromosome 12 at 75,391,832 bp
  • A to G, chromosome 12 at 84,147,350 bp
  • A to G, chromosome 12 at 103,417,414 bp
  • A to C, chromosome 13 at 98,859,937 bp
  • A to T, chromosome 14 at 20,739,347 bp
  • T to C, chromosome 14 at 50,654,068 bp
  • G to T, chromosome 14 at 53,599,387 bp
  • T to C, chromosome 15 at 28,311,152 bp
  • T to C, chromosome 16 at 23,496,247 bp
  • A to G, chromosome 16 at 59,554,610 bp
  • C to A, chromosome 16 at 84,860,409 bp
  • C to T, chromosome 16 at 91,657,490 bp
  • A to T, chromosome 16 at 96,033,843 bp
  • G to A, chromosome 17 at 35,881,688 bp
  • T to C, chromosome 18 at 78,116,414 bp
  • T to C, chromosome 19 at 6,122,110 bp
  • T to C, chromosome 19 at 6,531,339 bp
  • G to T, chromosome 19 at 43,704,266 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5763 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043364-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.