Strain Name:
C57BL/6J-MtgxR5765Btlr
Stock Number:
043366-MU
Citation ID:
RRID:MMRRC_043366-MU
Other Names:
R5765 (G1)
Major Collection:

Gene Information

Cntnap2
Name: contactin associated protein-like 2
Synonyms: 5430425M22Rik, Caspr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66797
Homologene: 69159
Fam117b
Name: family with sequence similarity 117, member B
Synonyms: Als2cr13, 6330416D14Rik, 2810425F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72750
Homologene: 18307
Tnpo1
Name: transportin 1
Synonyms: D13Ertd688e, Kpnb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238799
HGNC: HGNC:6401
Homologene: 5358
Ptprz1
Name: protein tyrosine phosphatase, receptor type Z, polypeptide 1
Synonyms: PTPzeta, PTPbeta, Rptpbeta, Ptpz, phosphacan, DSD-1-PG, RPTPz, Ptprz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Slc17a6
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
Synonyms: 2900073D12Rik, VGLUT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 140919
Homologene: 121617
Tiparp
Name: TCDD-inducible poly(ADP-ribose) polymerase
Synonyms: DDF1, PARP-7, PARP7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99929
Homologene: 9167
Foxp1
Name: forkhead box P1
Synonyms: 4932443N09Rik, 3110052D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 108655
HGNC: HGNC:3823
Homologene: 13092
Nsfl1c
Name: NSFL1 (p97) cofactor (p47)
Synonyms: p47
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 386649
Homologene: 41114
Nbea
Name: neurobeachin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 26422
HGNC: HGNC:7648
Homologene: 69190
Med13l
Name: mediator complex subunit 13-like
Synonyms: Trap240L, 9030618F05Rik, 6330591G05Rik, Thrap2, 2210413I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 76199
Homologene: 25256
Luzp1
Name: leucine zipper protein 1
Synonyms: 2700072H04Rik, Luzp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269593
Homologene: 11545
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: 8430405D05Rik, C130099L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 195018
Homologene: 9027
Strn3
Name: striatin, calmodulin binding protein 3
Synonyms: SG2NA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 94186
VEGA: 12
Homologene: 82078
Ppp6r1
Name: protein phosphatase 6, regulatory subunit 1
Synonyms: Pp6r1, Saps1, B430201G11Rik, 2010309P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243819
Homologene: 86982
Abcf2
Name: ATP-binding cassette, sub-family F (GCN20), member 2
Synonyms: 0710005O05Rik, Drr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 27407
HGNC: HGNC:71
Homologene: 21408
Tsc22d4
Name: TSC22 domain family, member 4
Synonyms: 0610009M14Rik, 1700023B23Rik, Thg-1pit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 78829
Homologene: 11390
Nbeal1
Name: neurobeachin like 1
Synonyms: A530083I02Rik, A530050O19Rik, 2310076G13Rik, ALS2CR17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269198
Homologene: 16453
Caprin2
Name: caprin family member 2
Synonyms: Eeg1, C1qdc1, RNG140
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232560
Homologene: 11393
Stradb
Name: STE20-related kinase adaptor beta
Synonyms: Als2cr2, D1Ucla2, PRO1038
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227154
Homologene: 10237
Pcdhac1
Name: protocadherin alpha subfamily C, 1
Synonyms: CNRc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 353236
HGNC: HGNC:8676
Homologene: 49561
Il1rl1
Name: interleukin 1 receptor-like 1
Synonyms: DER4, St2-rs1, St2, Ly84, T1, ST2L, T1/ST2, ST2, Fit-1, T1 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17082
HGNC: HGNC:5998
Homologene: 2862
Vmn2r116
Name: vomeronasal 2, receptor 116
Synonyms: EG619697, V2Rp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 619697
Homologene: 86604
Nalcn
Name: sodium leak channel, non-selective
Synonyms: Vgcnl1, A530023G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 338370
VEGA: 14
Homologene: 21832
Synpo2l
Name: synaptopodin 2-like
Synonyms: 1110054M18Rik, Chap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68760
Homologene: 23499
Kif2b
Name: kinesin family member 2B
Synonyms: 1700063D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 73470
Homologene: 23775
Adamts19
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19
Synonyms: D230034E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240322
VEGA: 18
Homologene: 15860
Fads2b
Name: fatty acid desaturase 2B
Synonyms: 4833423E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228151
Homologene: 105643
Ugt2b38
Name: UDP glucuronosyltransferase 2 family, polypeptide B38
Synonyms: 9430041C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100559
Homologene: 137225
Ugt2b1
Name: UDP glucuronosyltransferase 2 family, polypeptide B1
Synonyms: 1300012D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71773
Homologene: 68144
Plin4
Name: perilipin 4
Synonyms: S3-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 57435
Homologene: 69311
Tas2r104
Name: taste receptor, type 2, member 104
Synonyms: T2R04, mt2r45, mGR04, Tas2r4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387340
Homologene: 130072
Fignl1
Name: fidgetin-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 60530
Homologene: 11063
Spock1
Name: sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
Synonyms: testican 1, Ticn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20745
Homologene: 80193
Iqce
Name: IQ motif containing E
Synonyms: 1700028P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74239
Homologene: 49912
Nfe2l3
Name: nuclear factor, erythroid derived 2, like 3
Synonyms: Nrf3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18025
HGNC: HGNC:7783
Homologene: 3168
Doxl2
Name: diamine oxidase-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243376
Homologene: 19443
Dnaaf2
Name: dynein, axonemal assembly factor 2
Synonyms: Ktu, 1110034A24Rik, kintoun, 2810020C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 109065
Homologene: 10026
Mtnr1b
Name: melatonin receptor 1B
Synonyms: Mt2, Mel1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244701
HGNC: HGNC:7464
Homologene: 4350
Fbxw22
Name: F-box and WD-40 domain protein 22
Synonyms: Gm5164
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382156
Homologene: 110776
Vmn2r97
Name: vomeronasal 2, receptor 97
Synonyms: EG627367
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627367
Homologene: 115024
Cd1d2
Name: CD1d2 antigen
Synonyms: CD1.2, Cd1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12480
HGNC: HGNC:1637
Cpm
Name: carboxypeptidase M
Synonyms: 5730456K23Rik, 1110060I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70574
HGNC: HGNC:2311
Homologene: 35367
Gdap1
Name: ganglioside-induced differentiation-associated-protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14545
Homologene: 40713
Adh7
Name: alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Synonyms: Adh-3e, Adh4, Adh3-t, Adh3-e, Adh3, IV ADH, Adh-3, Adt-1, Adh-3t
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11529
HGNC: HGNC:256
Homologene: 37333
H2-M3
Name: histocompatibility 2, M region locus 3
Synonyms: R4B2, H-2M3, Hmt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14991
HGNC: HGNC:4964
Homologene: 133255
Casp7
Name: caspase 7
Synonyms: Mch3, ICE-IAP3, caspase-7, CMH-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 12369
VEGA: 19
HGNC: HGNC:1508
Homologene: 11168
Mocs2
Name: molybdenum cofactor synthesis 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17434
HGNC: HGNC:7193
Homologene: 32193
Sh3bp5
Name: SH3-domain binding protein 5 (BTK-associated)
Synonyms: Sab
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 24056
Homologene: 23450
Zfand2b
Name: zinc finger, AN1 type domain 2B
Synonyms: 1110060O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68818
Homologene: 32671
Pcdhga1
Name: protocadherin gamma subfamily A, 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93709
HGNC: HGNC:8696
Homologene: 56824
1700086D15Rik
Name: RIKEN cDNA 1700086D15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74282
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 17,161,426 bp
  • C to T, chromosome 1 at 40,461,943 bp
  • C to A, chromosome 1 at 58,992,744 bp
  • A to G, chromosome 1 at 59,970,472 bp
  • T to A, chromosome 1 at 60,291,847 bp
  • T to A, chromosome 1 at 75,170,527 bp
  • T to G, chromosome 2 at 85,484,194 bp
  • T to C, chromosome 2 at 151,504,165 bp
  • C to T, chromosome 3 at 56,005,298 bp
  • T to A, chromosome 3 at 65,531,350 bp
  • A to T, chromosome 3 at 86,987,242 bp
  • G to A, chromosome 3 at 138,226,329 bp
  • T to C, chromosome 4 at 136,541,029 bp
  • T to C, chromosome 5 at 24,573,423 bp
  • T to C, chromosome 5 at 86,919,406 bp
  • A to G, chromosome 5 at 87,424,095 bp
  • T to A, chromosome 5 at 118,728,642 bp
  • A to G, chromosome 5 at 137,758,543 bp
  • A to G, chromosome 5 at 140,666,140 bp
  • T to G, chromosome 6 at 23,000,236 bp
  • C to T, chromosome 6 at 46,529,815 bp
  • C to T, chromosome 6 at 48,978,537 bp
  • A to G, chromosome 6 at 51,457,246 bp
  • G to A, chromosome 6 at 99,015,462 bp
  • A to G, chromosome 6 at 131,685,273 bp
  • G to C, chromosome 6 at 148,843,168 bp
  • C to A, chromosome 7 at 4,642,208 bp
  • A to G, chromosome 7 at 51,625,501 bp
  • T to C, chromosome 9 at 15,863,163 bp
  • T to C, chromosome 9 at 109,384,996 bp
  • A to G, chromosome 10 at 117,671,733 bp
  • T to C, chromosome 11 at 11,802,011 bp
  • A to T, chromosome 11 at 65,153,240 bp
  • C to T, chromosome 11 at 72,821,937 bp
  • C to T, chromosome 11 at 91,577,242 bp
  • A to G, chromosome 12 at 51,633,627 bp
  • A to C, chromosome 12 at 69,192,853 bp
  • A to T, chromosome 13 at 57,429,404 bp
  • G to A, chromosome 13 at 98,859,841 bp
  • A to G, chromosome 13 at 114,826,156 bp
  • C to T, chromosome 14 at 20,666,130 bp
  • C to A, chromosome 14 at 31,377,495 bp
  • C to T, chromosome 14 at 123,464,726 bp
  • T to A, chromosome 17 at 18,947,180 bp
  • G to A, chromosome 17 at 23,401,404 bp
  • T to C, chromosome 17 at 37,272,443 bp
  • C to T, chromosome 17 at 56,102,470 bp
  • A to T, chromosome 18 at 37,090,319 bp
  • A to G, chromosome 18 at 37,663,661 bp
  • G to T, chromosome 18 at 59,052,582 bp
  • T to C, chromosome 19 at 56,433,883 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5765 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043366-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.