Strain Name:
C57BL/6J-MtgxR5768Btlr
Stock Number:
043368-MU
Citation ID:
RRID:MMRRC_043368-MU
Other Names:
R5768 (G1)
Major Collection:

Gene Information

Dnmt3a
Name: DNA methyltransferase 3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13435
HGNC: HGNC:2978
Homologene: 7294
Htr6
Name: 5-hydroxytryptamine (serotonin) receptor 6
Synonyms: 5-HT6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15565
HGNC: HGNC:5301
Homologene: 673
Polr2f
Name: polymerase (RNA) II (DNA directed) polypeptide F
Synonyms: RNA Pol II, 1810060D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 69833
VEGA: 15
HGNC: HGNC:9193
Homologene: 7178
Msi2
Name: musashi RNA-binding protein 2
Synonyms: msi2h, Musashi2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76626
Homologene: 62199
Hira
Name: histone cell cycle regulator
Synonyms: Tuple1, D16Ertd95e, Gm15797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 15260
HGNC: HGNC:4916
Homologene: 48172
Cryzl1
Name: crystallin, zeta (quinone reductase)-like 1
Synonyms: 2210407J23Rik, 2410006O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 66609
HGNC: HGNC:2420
Homologene: 3749
BC004004
Name: cDNA sequence BC004004
Synonyms: 2400006G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 80748
Homologene: 12728
Dip2b
Name: disco interacting protein 2 homolog B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239667
Homologene: 72227
Pi4ka
Name: phosphatidylinositol 4-kinase alpha
Synonyms: Pik4ca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224020
HGNC: HGNC:8983
Homologene: 11171
Atxn10
Name: ataxin 10
Synonyms: TEG-169, E46, Sca10, Tex169
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 54138
VEGA: 15
Homologene: 40858
Oprm1
Name: opioid receptor, mu 1
Synonyms: MOR-1, muOR, mor, Oprm, MOP-R, MOP receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18390
HGNC: HGNC:8156
Homologene: 37368
Nectin3
Name: nectin cell adhesion molecule 3
Synonyms: nectin-3, 4921513D19Rik, 2610301B19Rik, 3000002N23Rik, Pvrl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 58998
Homologene: 9162
Cand1
Name: cullin associated and neddylation disassociated 1
Synonyms: 6330512O03Rik, 2310038O07Rik, D10Ertd516e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71902
Homologene: 10202
Ddi2
Name: DNA-damage inducible protein 2
Synonyms: 9130022E05Rik, 1110056G13Rik, 1700027M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68817
Homologene: 121661
Eps15
Name: epidermal growth factor receptor pathway substrate 15
Synonyms: 2410112D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13858
HGNC: HGNC:3419
Homologene: 128359
Grpel1
Name: GrpE-like 1, mitochondrial
Synonyms: mt-GrpE#1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17713
Homologene: 6992
Zfhx2
Name: zinc finger homeobox 2
Synonyms: zfh-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239102
Homologene: 52657
Cd209d
Name: CD209d antigen
Synonyms: SIGNR3, mSIGNR3, SIGN-R3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 170779
HGNC: HGNC:1641
Homologene: 8603
Susd2
Name: sushi domain containing 2
Synonyms: 1200011D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71733
VEGA: 10
Homologene: 10481
Cacna1c
Name: calcium channel, voltage-dependent, L type, alpha 1C subunit
Synonyms: (alpha)1 subunit, Cchl1a1, Cav1.2, L-type Cav1.2, D930026N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12288
HGNC: HGNC:1390
Homologene: 55484
Psd
Name: pleckstrin and Sec7 domain containing
Synonyms: Efa6, 1110007H17Rik, Psdl, Efa6a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 73728
VEGA: 19
HGNC: HGNC:9507
Homologene: 31115
Cst11
Name: cystatin 11
Synonyms: 9230101F08Rik, CRES2, mCST E1, cystatin E1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 78240
Homologene: 15634
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Cdhr3
Name: cadherin-related family member 3
Synonyms: 1110049B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68764
VEGA: 12
Homologene: 45146
Madd
Name: MAP-kinase activating death domain
Synonyms: 9630059K23Rik, Rab3 GEP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228355
HGNC: HGNC:6766
Homologene: 14249
Ddb2
Name: damage specific DNA binding protein 2
Synonyms: p48, 2610043A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 107986
HGNC: HGNC:2718
Homologene: 83
Rfx6
Name: regulatory factor X, 6
Synonyms: 4930572O07Rik, Rfxdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 320995
Homologene: 18318
Mppe1
Name: metallophosphoesterase 1
Synonyms: Pgap5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225651
VEGA: 18
Homologene: 41512
Papss2
Name: 3'-phosphoadenosine 5'-phosphosulfate synthase 2
Synonyms: Sk2, Atpsk2, 1810018P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 23972
VEGA: 19
HGNC: HGNC:8604
Homologene: 55840
Plekha6
Name: pleckstrin homology domain containing, family A member 6
Synonyms: Pepp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240753
Homologene: 135779
Tgfbr3
Name: transforming growth factor, beta receptor III
Synonyms: betaglycan, TBRIII, 1110036H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 21814
Homologene: 2436
Ccdc69
Name: coiled-coil domain containing 69
Synonyms: 2210021E03Rik, D11Ertd461e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 52570
Homologene: 77613
Adam22
Name: a disintegrin and metallopeptidase domain 22
Synonyms: MDC2, 2900022I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11496
HGNC: HGNC:201
Homologene: 37898
Sdk1
Name: sidekick cell adhesion molecule 1
Synonyms: 6720466O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330222
Homologene: 27395
Hsd11b1
Name: hydroxysteroid 11-beta dehydrogenase 1
Synonyms: 11beta-hydroxysteroid dehydrogenase type 1, 11beta-HSD-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 15483
HGNC: HGNC:5208
Homologene: 68471
Nfasc
Name: neurofascin
Synonyms: D430023G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269116
Homologene: 24945
Elf5
Name: E74-like factor 5
Synonyms: ESE-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13711
HGNC: HGNC:3320
Homologene: 135967
Tchh
Name: trichohyalin
Synonyms: Thh, AHF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99681
Homologene: 136273
Tmtc4
Name: transmembrane and tetratricopeptide repeat containing 4
Synonyms: 5730419O14Rik, 4930403J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 70551
Homologene: 32796
Lrfn5
Name: leucine rich repeat and fibronectin type III domain containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238205
Homologene: 17582
Cherp
Name: calcium homeostasis endoplasmic reticulum protein
Synonyms: 5730408I11Rik, SCAF6, DAN16, D8Wsu96e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 27967
Homologene: 4656
Akp3
Name: alkaline phosphatase 3, intestine, not Mn requiring
Synonyms: IAP, Akp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11648
Homologene: 134333
Clip4
Name: CAP-GLY domain containing linker protein family, member 4
Synonyms: 1700074B05Rik, 5830409B12Rik, 4833417L20Rik, 1700024K14Rik, Rsnl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 78785
VEGA: 17
Homologene: 11662
Ipp
Name: IAP promoted placental gene
Synonyms: D4Jhu8, Mipp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16351
HGNC: HGNC:6108
Homologene: 4309
Gc
Name: vitamin D binding protein
Synonyms: DBP, vitamin D binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14473
HGNC: HGNC:4187
Homologene: 486
Olfr194
Name: olfactory receptor 194
Synonyms: GA_x54KRFPKG5P-55348161-55347241, MOR182-7P, MOR182-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 433031
Homologene: 122781
Bin1
Name: bridging integrator 1
Synonyms: Amphl, Amphiphysin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 30948
VEGA: 18
HGNC: HGNC:1052
Homologene: 113707
Map2k7
Name: mitogen-activated protein kinase kinase 7
Synonyms: MKK7, sek2, MAP kinase kinase 7, Jnkk2, Prkmk7, 5930412N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 26400
HGNC: HGNC:6847
Homologene: 56548
Tmed1
Name: transmembrane p24 trafficking protein 1
Synonyms: St2l, Ly84l, Il1rl1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17083
VEGA: 9
Homologene: 21360
Olfr1222
Name: olfactory receptor 1222
Synonyms: GA_x6K02T2Q125-50604368-50603433, MOR233-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258177
Homologene: 73988
Fra10ac1
Name: FRA10AC1 homolog (human)
Synonyms: 5730455O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 70567
VEGA: 19
HGNC: HGNC:1162
Homologene: 13852
Spock2
Name: sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
Synonyms: testican-2, Gcap26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 94214
Homologene: 8854
Rpp25l
Name: ribonuclease P/MRP 25 subunit-like
Synonyms: 2810432D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69961
Homologene: 41714
Dfna5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 87,127,122 bp
  • T to C, chromosome 1 at 132,605,145 bp
  • A to G, chromosome 1 at 133,280,378 bp
  • T to A, chromosome 1 at 193,240,246 bp
  • T to C, chromosome 2 at 89,125,449 bp
  • T to A, chromosome 2 at 91,167,829 bp
  • T to C, chromosome 2 at 91,211,992 bp
  • C to T, chromosome 2 at 103,449,022 bp
  • T to C, chromosome 2 at 112,753,097 bp
  • A to T, chromosome 2 at 148,770,467 bp
  • A to T, chromosome 3 at 93,446,181 bp
  • A to T, chromosome 4 at 41,712,649 bp
  • C to G, chromosome 4 at 109,363,176 bp
  • A to C, chromosome 4 at 116,510,770 bp
  • G to A, chromosome 4 at 139,061,704 bp
  • A to T, chromosome 4 at 141,685,590 bp
  • G to A, chromosome 5 at 8,127,426 bp
  • A to T, chromosome 5 at 36,465,159 bp
  • T to C, chromosome 5 at 89,441,266 bp
  • T to C, chromosome 5 at 107,149,895 bp
  • C to A, chromosome 5 at 142,143,871 bp
  • G to A, chromosome 6 at 50,219,300 bp
  • A to G, chromosome 6 at 118,697,680 bp
  • T to A, chromosome 8 at 3,871,968 bp
  • T to A, chromosome 8 at 4,245,757 bp
  • C to T, chromosome 8 at 72,463,113 bp
  • T to C, chromosome 9 at 21,509,323 bp
  • G to A, chromosome 10 at 6,789,026 bp
  • G to A, chromosome 10 at 51,726,880 bp
  • T to A, chromosome 10 at 60,126,207 bp
  • C to T, chromosome 10 at 75,638,019 bp
  • A to G, chromosome 10 at 119,211,005 bp
  • T to C, chromosome 11 at 55,055,030 bp
  • A to G, chromosome 11 at 88,717,738 bp
  • G to A, chromosome 12 at 3,885,660 bp
  • G to T, chromosome 12 at 33,046,686 bp
  • G to A, chromosome 12 at 61,839,723 bp
  • T to C, chromosome 14 at 55,074,365 bp
  • T to A, chromosome 14 at 122,933,153 bp
  • A to G, chromosome 15 at 79,151,645 bp
  • A to T, chromosome 15 at 85,393,420 bp
  • C to A, chromosome 15 at 100,157,945 bp
  • T to C, chromosome 16 at 17,354,872 bp
  • T to C, chromosome 16 at 18,935,018 bp
  • T to C, chromosome 16 at 46,458,817 bp
  • TGAAGAAGAA to TGAAGAA, chromosome 16 at 59,119,972 bp
  • C to T, chromosome 16 at 91,695,354 bp
  • A to T, chromosome 17 at 29,282,735 bp
  • T to A, chromosome 17 at 71,806,499 bp
  • T to A, chromosome 18 at 32,426,211 bp
  • T to G, chromosome 18 at 67,225,818 bp
  • G to A, chromosome 19 at 32,660,719 bp
  • T to C, chromosome 19 at 38,207,286 bp
  • T to C, chromosome 19 at 46,312,739 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5768 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043368-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.