Strain Name:
C57BL/6J-MtgxR5807Btlr/Mmmh
Stock Number:
043393-MU
Citation ID:
RRID:MMRRC_043393-MU
Other Names:
R5807 (G1)
Major Collection:

Strain Information

Fn1
Name: fibronectin 1
Synonyms: Fn-1, Fn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14268
HGNC: HGNC:3778
Homologene: 1533
Chrna7
Name: cholinergic receptor, nicotinic, alpha polypeptide 7
Synonyms: Acra7, alpha7, alpha7 nicotinic receptor, alpha7-nAChR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11441
Homologene: 593
Gcg
Name: glucagon
Synonyms: GLP-1, glucagon-like peptide I, Glu, PPG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14526
HGNC: HGNC:4191
Homologene: 1553
Abca12
Name: ATP-binding cassette, sub-family A (ABC1), member 12
Synonyms: 4832428G11Rik, 4833417A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74591
Homologene: 45441
Phf12
Name: PHD finger protein 12
Synonyms: PF1, 2410142K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268448
Homologene: 10841
Tns3
Name: tensin 3
Synonyms: TEM6, F830010I22Rik, Tens1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 319939
Homologene: 49713
Wee1
Name: WEE 1 homolog 1 (S. pombe)
Synonyms: Wee1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22390
Homologene: 31152
Golga4
Name: golgi autoantigen, golgin subfamily a, 4
Synonyms: golgin-245, Olp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 54214
HGNC: HGNC:4427
Homologene: 68224
Prim2
Name: DNA primase, p58 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19076
HGNC: HGNC:9370
Homologene: 731
Esrrb
Name: estrogen related receptor, beta
Synonyms: Estrrb, ERRb, ERR2, Err2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 26380
HGNC: HGNC:3473
Homologene: 69108
Eif2ak4
Name: eukaryotic translation initiation factor 2 alpha kinase 4
Synonyms: GCN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27103
Homologene: 40891
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F32S1, D15F32S1h, D7H15F37S1, rjs, jdf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Fbxo21
Name: F-box protein 21
Synonyms: 2810425J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231670
Homologene: 14145
Abcg5
Name: ATP binding cassette subfamily G member 5
Synonyms: Sterolin-1, trac, cmp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 27409
Homologene: 31909
Ptpn6
Name: protein tyrosine phosphatase, non-receptor type 6
Synonyms: SHP-1, Ptp1C, hcp, Hcph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 15170
HGNC: HGNC:9658
Homologene: 56589
Ddx52
Name: DExD box helicase 52
Synonyms: ROK1, 2700029C06Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 78394
Homologene: 5093
Ndufs6
Name: NADH:ubiquinone oxidoreductase core subunit S6
Synonyms: IP13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 407785
HGNC: HGNC:7713
Homologene: 37935
Atp5b
Name: ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11947
HGNC: HGNC:830
Homologene: 1273
Avpr1a
Name: arginine vasopressin receptor 1A
Synonyms: V1aR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 54140
HGNC: HGNC:895
Homologene: 568
Rtn3
Name: reticulon 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20168
VEGA: 19
Homologene: 24934
Cep295
Name: centrosomal protein 295
Synonyms: LOC382128, 5830418K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319675
Homologene: 27936
Kcnu1
Name: potassium channel, subfamily U, member 1
Synonyms: Slo3, Kcnma3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16532
Homologene: 7392
Col28a1
Name: collagen, type XXVIII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 213945
Homologene: 66345
Tnr
Name: tenascin R
Synonyms: janusin, restrictin, TN-R, J1-tenascin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21960
Homologene: 124416
Fer1l6
Name: fer-1-like 6 (C. elegans)
Synonyms: EG631797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 631797
Homologene: 53396
Vmn2r116
Name: vomeronasal 2, receptor 116
Synonyms: EG619697, V2Rp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 619697
Homologene: 86604
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Krtap9-5
Name: keratin associated protein 9-5
Synonyms: OTTMUSG00000002205
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 435286
Homologene: 135766
Inhbc
Name: inhibin beta-C
Synonyms: activin beta-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16325
VEGA: 10
HGNC: HGNC:6068
Homologene: 21142
Atp11b
Name: ATPase, class VI, type 11B
Synonyms: 1110019I14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76295
Homologene: 32919
Osbpl6
Name: oxysterol binding protein-like 6
Synonyms: ORP-6, 1110062M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99031
Homologene: 101447
Arhgef4
Name: Rho guanine nucleotide exchange factor (GEF) 4
Synonyms: 9330140K16Rik, Asef, C230030N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226970
HGNC: HGNC:684
Homologene: 49414
Arfgef3
Name: ARFGEF family member 3
Synonyms: B930094H20Rik, D10Bwg1379e, BIG3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215821
VEGA: 10
Homologene: 41366
Krt84
Name: keratin 84
Synonyms: HRb-1, Krt2-3, Krt2-16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16680
VEGA: 15
HGNC: HGNC:6461
Homologene: 22473
Pla2r1
Name: phospholipase A2 receptor 1
Synonyms: PLA2-I receptor, M-type receptor, Pla2g1br
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18779
HGNC: HGNC:9042
Homologene: 32016
Cpb1
Name: carboxypeptidase B1 (tissue)
Synonyms: 2210008M23Rik, 0910001A18Rik, 1810063F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76703
HGNC: HGNC:2299
Homologene: 68127
Or10n1
Name: olfactory receptor family 10 subfamily N member 1
Synonyms: M30, MOR224-4, GA_x6K02T2PVTD-33310486-33311418, Olfr148
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258498
VEGA: 9
Homologene: 128136
Atp9a
Name: ATPase, class II, type 9A
Synonyms: Class II, IIa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11981
Homologene: 69194
Cyp2c50
Name: cytochrome P450, family 2, subfamily c, polypeptide 50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107141
Homologene: 137231
Slc25a34
Name: solute carrier family 25, member 34
Synonyms: LOC384071
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 384071
Homologene: 68806
Ripk3
Name: receptor-interacting serine-threonine kinase 3
Synonyms: Rip3, 2610528K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56532
VEGA: 14
Homologene: 31410
Bmp2k
Name: BMP2 inducible kinase
Synonyms: BIKE, 4933417M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 140780
Homologene: 34134
Mrgprb3
Name: MAS-related GPR, member B3
Synonyms: MrgB3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 404238
Homologene: 138632
Slamf1
Name: signaling lymphocytic activation molecule family member 1
Synonyms: IPO-3, CD150, ESTM51, CDw150, Slam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 27218
Homologene: 48162
Cnr2
Name: cannabinoid receptor 2 (macrophage)
Synonyms: CB2-R, cannabinoid receptor 2 (spleen), CB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12802
HGNC: HGNC:2160
Homologene: 1389
Or51a25
Name: olfactory receptor family 51 subfamily A member 25
Synonyms: GA_x6K02T2PBJ9-5441154-5440198, MOR11-1, Olfr559
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259116
Homologene: 74124
Glis1
Name: GLIS family zinc finger 1
Synonyms: GliH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230587
Homologene: 77390
Tmem38a
Name: transmembrane protein 38A
Synonyms: 1110001E17Rik, TRIC-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74166
Homologene: 11449
Klhdc3
Name: kelch domain containing 3
Synonyms: 1300011D16Rik, Peas
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71765
VEGA: 17
Homologene: 14290
Pdilt
Name: protein disulfide isomerase-like, testis expressed
Synonyms: PDILT, 1700007B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71830
Homologene: 18382
Fcamr
Name: Fc receptor, IgA, IgM, high affinity
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 64435
Homologene: 12929
Gm8444
Name: predicted gene 8444
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 667073
VEGA: 15
Efcab1
Name: EF-hand calcium binding domain 1
Synonyms: 4930449A16Rik, 5430404L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 66793
VEGA: 16
Homologene: 11608
Or13c7b
Name: olfactory receptor family 13 subfamily C member 7B
Synonyms: OR37B, mOR37b, Olfr37b, MOR262-6, GA_x6K02T2N78B-16125144-16126100, Olfr156
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 29846
Homologene: 133652
Gpr132
Name: G protein-coupled receptor 132
Synonyms: G2 accumulation, G2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56696
VEGA: 12
Homologene: 8350
Gm266
Name: predicted gene 266
Synonyms: LOC212539
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 212539
VEGA: 12
Homologene: 19334
Ang
Name: angiogenin, ribonuclease, RNase A family, 5
Synonyms: Rnase5a, Ang1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 11727
VEGA: 14
HGNC: HGNC:483
Homologene: 74385
Rnase1
Name: ribonuclease, RNase A family, 1 (pancreatic)
Synonyms: Rib-1, Rib1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19752
VEGA: 14
Homologene: 7919
Qpctl
Name: glutaminyl-peptide cyclotransferase-like
Synonyms: 1810019P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67369
Homologene: 9765
Gvin-ps5
Name: GTPase, very large interferon inducible, pseudogene 5
Synonyms: Gm8989, Gm21911
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 668128
Gm5070
Name: predicted gene 5070
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 277589
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 33,480,406 bp
  • A to G, chromosome 1 at 34,807,615 bp
  • A to G, chromosome 1 at 71,303,492 bp
  • T to C, chromosome 1 at 71,648,059 bp
  • T to C, chromosome 1 at 130,811,526 bp
  • C to T, chromosome 1 at 159,886,930 bp
  • A to G, chromosome 1 at 171,775,062 bp
  • C to T, chromosome 2 at 60,428,721 bp
  • A to G, chromosome 2 at 62,475,725 bp
  • A to G, chromosome 2 at 76,584,513 bp
  • G to T, chromosome 2 at 118,388,851 bp
  • G to A, chromosome 2 at 168,653,534 bp
  • T to A, chromosome 3 at 20,263,742 bp
  • T to C, chromosome 3 at 35,812,279 bp
  • C to A, chromosome 3 at 95,410,654 bp
  • C to A, chromosome 4 at 43,820,912 bp
  • T to A, chromosome 4 at 107,568,082 bp
  • A to G, chromosome 4 at 135,917,436 bp
  • A to G, chromosome 4 at 141,623,662 bp
  • T to C, chromosome 5 at 97,063,494 bp
  • A to G, chromosome 5 at 117,976,868 bp
  • T to A, chromosome 6 at 8,158,144 bp
  • T to C, chromosome 6 at 124,724,984 bp
  • G to T, chromosome 7 at 19,143,207 bp
  • A to G, chromosome 7 at 48,643,362 bp
  • T to A, chromosome 7 at 56,230,919 bp
  • T to A, chromosome 7 at 63,148,601 bp
  • C to T, chromosome 7 at 102,724,202 bp
  • T to A, chromosome 7 at 106,330,223 bp
  • TCCCC to TCCC, chromosome 7 at 110,124,569 bp
  • A to G, chromosome 7 at 119,500,543 bp
  • C to T, chromosome 8 at 25,849,714 bp
  • A to G, chromosome 8 at 72,580,100 bp
  • A to G, chromosome 9 at 15,332,532 bp
  • A to G, chromosome 9 at 39,614,463 bp
  • A to G, chromosome 9 at 118,527,130 bp
  • A to G, chromosome 10 at 18,647,798 bp
  • A to G, chromosome 10 at 122,449,471 bp
  • C to A, chromosome 10 at 127,357,542 bp
  • G to A, chromosome 10 at 128,088,562 bp
  • T to C, chromosome 11 at 8,493,211 bp
  • T to C, chromosome 11 at 59,079,650 bp
  • C to A, chromosome 11 at 78,022,426 bp
  • T to G, chromosome 11 at 83,949,682 bp
  • T to A, chromosome 11 at 99,949,069 bp
  • A to G, chromosome 12 at 86,514,401 bp
  • T to C, chromosome 12 at 111,485,739 bp
  • G to A, chromosome 12 at 112,852,796 bp
  • A to T, chromosome 13 at 73,327,434 bp
  • T to A, chromosome 14 at 51,101,429 bp
  • A to G, chromosome 14 at 51,145,450 bp
  • T to A, chromosome 14 at 55,785,298 bp
  • C to A, chromosome 15 at 58,590,550 bp
  • T to C, chromosome 15 at 81,843,453 bp
  • T to A, chromosome 15 at 101,530,212 bp
  • A to T, chromosome 16 at 14,916,972 bp
  • T to A, chromosome 17 at 23,387,307 bp
  • T to C, chromosome 17 at 46,677,465 bp
  • C to A, chromosome 17 at 84,672,291 bp
  • T to A, chromosome 19 at 7,456,827 bp
  • T to C, chromosome 19 at 40,113,500 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5807 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043393-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.