Strain Name:
C57BL/6J-MtgxR5832Btlr
Stock Number:
044054-MU
Citation ID:
RRID:MMRRC_044054-MU
Other Names:
R5832 (G1)
Major Collection:

Gene Information

Kitl
Name: kit ligand
Synonyms: Gb, SCF, Steel, Mgf, Sl, Kitlg, SF, grizzle-belly, blz, stem cell factor, Steel factor, SLF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 17311
HGNC: HGNC:6343
Homologene: 692
Mc3r
Name: melanocortin 3 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17201
HGNC: HGNC:6931
Homologene: 7412
Prkcd
Name: protein kinase C, delta
Synonyms: PKC[d], D14Ertd420e, Pkcd, PKCdelta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 18753
HGNC: HGNC:9399
Homologene: 55963
Galr2
Name: galanin receptor 2
Synonyms: mGalR, GalR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14428
HGNC: HGNC:4133
Homologene: 2863
Iqgap2
Name: IQ motif containing GTPase activating protein 2
Synonyms: 4933417J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 544963
VEGA: 13
HGNC: HGNC:6111
Homologene: 101543
Patz1
Name: POZ (BTB) and AT hook containing zinc finger 1
Synonyms: Zfp278, MAZR, POZ-AT hook-zinc finger protein, 8430401L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 56218
Homologene: 8636
Nav2
Name: neuron navigator 2
Synonyms: RAINB2, HELAD1, Unc53H2, 5330421F07Rik, POMFIL2, Rainb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 78286
Homologene: 52330
Tcof1
Name: treacle ribosome biogenesis factor 1
Synonyms: treacle
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 21453
Homologene: 68049
Trim66
Name: tripartite motif-containing 66
Synonyms: D7H11orf29, Tif1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 330627
Homologene: 28044
Sarnp
Name: SAP domain containing ribonucleoprotein
Synonyms: 1110005A23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66118
VEGA: 10
Homologene: 41628
Lmo7
Name: LIM domain only 7
Synonyms: FBXO20, LOC380928
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Hk1
Name: hexokinase 1
Synonyms: Hk1-s, Hk-1, mHk1-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 15275
HGNC: HGNC:4922
Homologene: 100530
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Ube2f
Name: ubiquitin-conjugating enzyme E2F (putative)
Synonyms: 2510010F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 67921
Homologene: 12212
Slc39a6
Name: solute carrier family 39 (metal ion transporter), member 6
Synonyms: Zip6, Ermelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 106957
Homologene: 8199
Eml5
Name: echinoderm microtubule associated protein like 5
Synonyms: C130068M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319670
VEGA: 12
Homologene: 26807
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225997
VEGA: 19
Homologene: 9767
Tnr
Name: tenascin R
Synonyms: restrictin, TN-R, janusin, J1-tenascin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 21960
Homologene: 124416
Mybpc3
Name: myosin binding protein C, cardiac
Synonyms: cardiac C-protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17868
HGNC: HGNC:7551
Homologene: 215
Tbc1d20
Name: TBC1 domain family, member 20
Synonyms: 1110028I04Rik, bs, 2810442O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67231
Homologene: 32574
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mgr1, Mass1, Gpr98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 110789
Homologene: 19815
Vmn2r77
Name: vomeronasal 2, receptor 77
Synonyms: EG546983
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 546983
Homologene: 115466
Srgap1
Name: SLIT-ROBO Rho GTPase activating protein 1
Synonyms: 4930572H05Rik, Arhgap13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 117600
Homologene: 56898
Slco1a4
Name: solute carrier organic anion transporter family, member 1a4
Synonyms: Oatp1a4, Oatp2, Slc21a5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28250
Homologene: 130782
Tshz2
Name: teashirt zinc finger family member 2
Synonyms: Zfp218, Tsh2, Mtsh2, teashirt2, Sdccag33l, 2900073F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228911
Homologene: 35258
Rsph4a
Name: radial spoke head 4 homolog A (Chlamydomonas)
Synonyms: Rshl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 212892
Homologene: 71779
Arfgef3
Name: ARFGEF family member 3
Synonyms: B930094H20Rik, D10Bwg1379e, BIG3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 215821
VEGA: 10
Homologene: 41366
Mep1a
Name: meprin 1 alpha
Synonyms: Mep-1a, Mep-1, Mep1, meprin A alpha-subunit, meprin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17287
HGNC: HGNC:7015
Homologene: 31323
Igfn1
Name: immunoglobulin-like and fibronectin type III domain containing 1
Synonyms: 9830123M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226438
Homologene: 130054
Zfp954
Name: zinc finger protein 954
Synonyms: 5730403M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232853
Homologene: 129792
Alox12
Name: arachidonate 12-lipoxygenase
Synonyms: P-12LO, 9930022G08Rik, Alox12p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11684
HGNC: HGNC:429
Homologene: 560
Pramef17
Name: PRAME family member 17
Synonyms: Gm13107
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 626943
Homologene: 129642
Lamp3
Name: lysosomal-associated membrane protein 3
Synonyms: DC-LAMP, 1200002D17Rik, Cd208, TSC403
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 239739
VEGA: 16
Homologene: 8670
Rcbtb2
Name: regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
Synonyms: 2810420M18Rik, Chc1l, Rc/btb2, 2610028E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105670
HGNC: HGNC:1914
Homologene: 970
Fhod3
Name: formin homology 2 domain containing 3
Synonyms: A930009H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225288
VEGA: 18
Homologene: 45323
Vmn2r109
Name: vomeronasal 2, receptor 109
Synonyms: EG627814
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627814
Homologene: 129678
4930505A04Rik
Name: RIKEN cDNA 4930505A04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75087
Homologene: 18988
Crisp1
Name: cysteine-rich secretory protein 1
Synonyms: CRISP-1, Aeg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 11571
Homologene: 135665
Gstm5
Name: glutathione S-transferase, mu 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 14866
HGNC: HGNC:4635
Homologene: 658
Gtpbp2
Name: GTP binding protein 2
Synonyms: nmf205
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 56055
HGNC: HGNC:4670
Homologene: 10420
Tbc1d22b
Name: TBC1 domain family, member 22B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 381085
Homologene: 23043
Anxa13
Name: annexin A13
Synonyms: 1810034H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 69787
VEGA: 15
HGNC: HGNC:536
Homologene: 20908
Asnsd1
Name: asparagine synthetase domain containing 1
Synonyms: 2210409M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 70396
Homologene: 6564
Spata31d1a
Name: spermatogenesis associated 31 subfamily D, member 1A
Synonyms: 1700013B16Rik, Fam75d1a, Fam75d3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 72219
VEGA: 13
Homologene: 122131
Pttg1ip
Name: pituitary tumor-transforming 1 interacting protein
Synonyms: 1810010L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 108705
Homologene: 3203
Gm28046
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 53,347,475 bp
  • T to G, chromosome 1 at 91,285,324 bp
  • A to G, chromosome 1 at 135,974,795 bp
  • A to G, chromosome 1 at 159,886,122 bp
  • A to G, chromosome 2 at 91,119,175 bp
  • A to T, chromosome 2 at 152,311,362 bp
  • T to A, chromosome 2 at 169,884,045 bp
  • T to A, chromosome 2 at 172,249,430 bp
  • T to C, chromosome 3 at 107,897,537 bp
  • A to G, chromosome 4 at 143,991,962 bp
  • A to G, chromosome 6 at 141,819,544 bp
  • A to G, chromosome 7 at 7,115,390 bp
  • A to T, chromosome 7 at 49,548,069 bp
  • T to A, chromosome 7 at 86,811,462 bp
  • A to G, chromosome 7 at 109,455,202 bp
  • A to T, chromosome 8 at 45,017,423 bp
  • C to T, chromosome 10 at 18,630,420 bp
  • A to G, chromosome 10 at 33,909,502 bp
  • T to C, chromosome 10 at 62,292,365 bp
  • T to C, chromosome 10 at 77,584,025 bp
  • C to A, chromosome 10 at 100,080,020 bp
  • T to G, chromosome 10 at 121,840,914 bp
  • T to A, chromosome 10 at 127,788,749 bp
  • T to C, chromosome 10 at 128,848,312 bp
  • C to T, chromosome 11 at 3,306,277 bp
  • C to T, chromosome 11 at 30,426,349 bp
  • T to C, chromosome 11 at 70,253,280 bp
  • T to A, chromosome 11 at 116,281,631 bp
  • T to C, chromosome 12 at 98,876,188 bp
  • A to T, chromosome 13 at 59,701,566 bp
  • G to A, chromosome 13 at 81,103,302 bp
  • C to T, chromosome 13 at 95,675,372 bp
  • T to C, chromosome 14 at 30,605,821 bp
  • C to A, chromosome 14 at 73,166,822 bp
  • A to T, chromosome 14 at 101,884,213 bp
  • C to A, chromosome 15 at 58,341,993 bp
  • A to T, chromosome 16 at 19,701,320 bp
  • C to T, chromosome 17 at 20,541,056 bp
  • T to C, chromosome 17 at 29,570,647 bp
  • A to G, chromosome 17 at 40,301,317 bp
  • G to A, chromosome 17 at 43,478,164 bp
  • C to T, chromosome 17 at 46,167,862 bp
  • C to A, chromosome 18 at 24,601,612 bp
  • T to C, chromosome 18 at 25,090,695 bp
  • G to T, chromosome 18 at 60,819,539 bp
  • A to G, chromosome 19 at 18,786,819 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5832 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044054-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.