Strain Name:
C57BL/6J-MtgxR5844Btlr
Stock Number:
044062-MU
Citation ID:
RRID:MMRRC_044062-MU
Other Names:
R5844 (G1)
Major Collection:

Gene Information

Smarca4
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Synonyms: b2b692Clo, SW1/SNF, b2b508.1Clo, Brg1, SNF2beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20586
Homologene: 135927
Tns3
Name: tensin 3
Synonyms: TEM6, Tens1, F830010I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 319939
Homologene: 49713
Map4k4
Name: mitogen-activated protein kinase kinase kinase kinase 4
Synonyms: Nik, 9430080K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 26921
HGNC: HGNC:6866
Homologene: 7442
Rfc1
Name: replication factor C (activator 1) 1
Synonyms: Alp145, 140kDa, RFC140, Recc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19687
HGNC: HGNC:9969
Homologene: 2187
Atf7ip
Name: activating transcription factor 7 interacting protein
Synonyms: ATFa-associated Modulator, 2610204M12Rik, Mcaf1, AM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 54343
Homologene: 10051
Sgo2a
Name: shugoshin 2A
Synonyms: 5730576N04Rik, 1110007N04Rik, Sgol2a, Tripin, Sgol2, D1Ertd8e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68549
Homologene: 51867
Rnd2
Name: Rho family GTPase 2
Synonyms: Rohn, Arhn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11858
Homologene: 21123
Hepacam2
Name: HEPACAM family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 101202
Homologene: 18724
Mtpn
Name: myotrophin
Synonyms: V1, 5033418D15Rik, Gcdp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14489
Homologene: 40607
Chd1l
Name: chromodomain helicase DNA binding protein 1-like
Synonyms: 4432404A22Rik, Snf2p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 68058
HGNC: HGNC:1916
Homologene: 11590
Slc38a9
Name: solute carrier family 38, member 9
Synonyms: 4833412L08Rik, 6720411P22Rik, 9130023D20Rik, 9430067K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 268706
VEGA: 13
Homologene: 18139
Eml2
Name: echinoderm microtubule associated protein like 2
Synonyms: 1600029N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72205
Homologene: 8125
Dse
Name: dermatan sulfate epimerase
Synonyms: B130024B19Rik, DS-epi1, Sart2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 212898
VEGA: 10
Homologene: 8354
Zmiz1
Name: zinc finger, MIZ-type containing 1
Synonyms: Rai17, Zimp10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 328365
Homologene: 10667
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: 9330101J02Rik, Ttc40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 212124
Tns2
Name: tensin 2
Synonyms: nep, Tenc1, nph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 209039
VEGA: 15
Homologene: 37077
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: FPC, tigmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Zim1
Name: zinc finger, imprinted 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22776
Homologene: 129793
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Pip4p1
Name: phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
Synonyms: Tmem55b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219024
Homologene: 10279
Mfsd6
Name: major facilitator superfamily domain containing 6
Synonyms: 9630025I22Rik, 2210010L05Rik, MMR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98682
Homologene: 9784
Catsperg2
Name: cation channel sperm associated auxiliary subunit gamma 2
Synonyms: CATSPERG, 1700067C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76718
Homologene: 10915
4930407I10Rik
Name: RIKEN cDNA 4930407I10 gene
Synonyms: LOC328573
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 328573
VEGA: 15
Homologene: 130065
Myom2
Name: myomesin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 17930
HGNC: HGNC:7614
Homologene: 2953
Galntl5
Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
Synonyms: 1700021B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 67909
Homologene: 12210
Trpm8
Name: transient receptor potential cation channel, subfamily M, member 8
Synonyms: CMR1, Trp-p8, TRPP8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 171382
Homologene: 23433
Grm5
Name: glutamate receptor, metabotropic 5
Synonyms: 6430542K11Rik, Glu5R, Gprc1e, mGluR5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 108071
HGNC: HGNC:4597
Homologene: 37354
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: Mll2, Mll4, C430014K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Ppp1r36
Name: protein phosphatase 1, regulatory subunit 36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 210762
VEGA: 12
Homologene: 52094
Rxfp2
Name: relaxin/insulin-like family peptide receptor 2
Synonyms: Great, Gpr106, LGR8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 140498
Homologene: 15402
Pde3b
Name: phosphodiesterase 3B, cGMP-inhibited
Synonyms: 9830102A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18576
HGNC: HGNC:8779
Homologene: 709
Ifi205
Name: interferon activated gene 205
Synonyms: D3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226695
HGNC: HGNC:5395
Homologene: 115929
Gtpbp3
Name: GTP binding protein 3
Synonyms: Gtpbp3, 2410009F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 70359
Homologene: 6600
Cfap43
Name: cilia and flagella associated protein 43
Synonyms: 4930428C11Rik, Wdr96, D19Ertd652e, 4930463G05Rik, 4632415N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 100048534
Homologene: 36425
Ccdc33
Name: coiled-coil domain containing 33
Synonyms: LOC382077, 4930535E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382077
Homologene: 19641
Skint9
Name: selection and upkeep of intraepithelial T cells 9
Synonyms: A030013N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 329918
Homologene: 136292
BC005624
Name: cDNA sequence BC005624
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227707
Homologene: 9551
Irs3
Name: insulin receptor substrate 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16369
HGNC: HGNC:6127
Homologene: 84788
Mis18a
Name: MIS18 kinetochore protein A
Synonyms: 2610039C10Rik, 2810018N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 66578
HGNC: HGNC:1286
Homologene: 41294
Dagla
Name: diacylglycerol lipase, alpha
Synonyms: Nsddr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 269060
HGNC: HGNC:1165
Homologene: 4468
Adra1a
Name: adrenergic receptor, alpha 1a
Synonyms: Adra1c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 11549
HGNC: HGNC:277
Homologene: 68078
Olfr211
Name: olfactory receptor 211
Synonyms: MOR253-9, GA_x54KRFPKN04-58127726-58128655
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 258914
Homologene: 17434
Cnksr1
Name: connector enhancer of kinase suppressor of Ras 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 194231
Homologene: 4604
Fbxo10
Name: F-box protein 10
Synonyms: LOC269529, FBX10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269529
Homologene: 19544
Olfr1002
Name: olfactory receptor 1002
Synonyms: GA_x6K02T2Q125-47127746-47126790, MOR175-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258566
Homologene: 104131
Wdyhv1
Name: WDYHV motif containing 1
Synonyms: 2410187C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 76773
VEGA: 15
Homologene: 9968
Cavin2
Name: caveolae associated 2
Synonyms: Sdpr, cavin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20324
Homologene: 3422
Cym
Name: chymosin
Synonyms: Gm131, LOC229697
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229697
Homologene: 129841
Runx1t1
Name: RUNX1 translocation partner 1
Synonyms: Cbfa2t1h, MTG8, ETO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12395
HGNC: HGNC:1535
Homologene: 3801
Tmem88
Name: transmembrane protein 88
Synonyms: 2600017H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67020
Homologene: 12073
Zfp853
Name: zinc finger protein 853
Synonyms: LOC330230
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330230
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 20,381,461 bp
  • T to A, chromosome 1 at 39,999,876 bp
  • C to T, chromosome 1 at 51,289,839 bp
  • T to C, chromosome 1 at 52,658,383 bp
  • T to G, chromosome 1 at 58,016,397 bp
  • T to C, chromosome 1 at 88,384,711 bp
  • A to C, chromosome 1 at 174,026,692 bp
  • T to C, chromosome 2 at 30,976,011 bp
  • A to G, chromosome 2 at 85,647,895 bp
  • T to A, chromosome 3 at 97,572,567 bp
  • T to C, chromosome 3 at 107,219,764 bp
  • T to C, chromosome 4 at 13,881,068 bp
  • A to T, chromosome 4 at 45,058,760 bp
  • T to C, chromosome 4 at 112,413,883 bp
  • A to G, chromosome 4 at 134,228,264 bp
  • G to T, chromosome 5 at 25,186,093 bp
  • C to A, chromosome 5 at 65,293,787 bp
  • T to C, chromosome 5 at 137,644,286 bp
  • C to T, chromosome 5 at 143,288,669 bp
  • A to G, chromosome 5 at 150,043,124 bp
  • A to G, chromosome 6 at 3,476,073 bp
  • C to T, chromosome 6 at 35,512,290 bp
  • A to T, chromosome 6 at 116,493,939 bp
  • C to A, chromosome 6 at 136,606,814 bp
  • T to C, chromosome 7 at 6,678,116 bp
  • G to A, chromosome 7 at 19,201,163 bp
  • A to T, chromosome 7 at 29,697,832 bp
  • A to G, chromosome 7 at 87,804,024 bp
  • C to T, chromosome 7 at 114,508,871 bp
  • TTCCTC to TTC, chromosome 7 at 119,951,021 bp
  • C to A, chromosome 7 at 139,650,942 bp
  • G to A, chromosome 8 at 15,131,182 bp
  • A to G, chromosome 8 at 71,492,555 bp
  • T to A, chromosome 9 at 21,677,942 bp
  • C to T, chromosome 9 at 58,033,206 bp
  • T to A, chromosome 10 at 34,153,042 bp
  • A to C, chromosome 11 at 8,434,580 bp
  • C to G, chromosome 11 at 69,397,678 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • A to G, chromosome 12 at 76,426,792 bp
  • A to G, chromosome 13 at 112,731,501 bp
  • T to C, chromosome 14 at 25,656,930 bp
  • T to C, chromosome 14 at 50,929,042 bp
  • C to T, chromosome 14 at 66,727,734 bp
  • A to G, chromosome 15 at 58,153,660 bp
  • A to T, chromosome 15 at 82,065,864 bp
  • G to A, chromosome 15 at 98,852,109 bp
  • C to T, chromosome 15 at 102,108,934 bp
  • G to A, chromosome 16 at 90,727,081 bp
  • T to A, chromosome 19 at 10,271,125 bp
  • T to C, chromosome 19 at 47,795,696 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5844 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044062-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.