Strain Name:
C57BL/6J-MtgxR5865Btlr
Stock Number:
044074-MU
Citation ID:
RRID:MMRRC_044074-MU
Other Names:
R5865 (G1)
Major Collection:

Gene Information

Mc3r
Name: melanocortin 3 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17201
HGNC: HGNC:6931
Homologene: 7412
Nphs1
Name: nephrosis 1, nephrin
Synonyms: nephrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 54631
HGNC: HGNC:7908
Homologene: 20974
Kcnc4
Name: potassium voltage gated channel, Shaw-related subfamily, member 4
Synonyms: Kcr2-4, Kv3.4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99738
HGNC: HGNC:6236
Homologene: 68427
Nfkb1
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Synonyms: p50 subunit of NF kappaB, p50/p105, NF-kappaB p50, NF-kappaB, NF kappaB1, nuclear factor kappaB p50, p50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18033
HGNC: HGNC:7794
Homologene: 2971
Psme4
Name: proteasome (prosome, macropain) activator subunit 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103554
Homologene: 113742
Tet2
Name: tet methylcytosine dioxygenase 2
Synonyms: E130014J05Rik, Ayu17-449
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 214133
Homologene: 49498
Zwilch
Name: zwilch kinetochore protein
Synonyms: 2310031L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68014
Homologene: 32381
Snx32
Name: sorting nexin 32
Synonyms: B930037P14Rik, Snx6b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225861
VEGA: 19
Homologene: 62637
Kank4
Name: KN motif and ankyrin repeat domains 4
Synonyms: Ankrd38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242553
Homologene: 18244
Ccdc187
Name: coiled-coil domain containing 187
Synonyms: 4932418E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329366
Homologene: 77630
Ccbe1
Name: collagen and calcium binding EGF domains 1
Synonyms: 4933426F18Rik, 9430093N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 320924
Homologene: 15852
Ms4a14
Name: membrane-spanning 4-domains, subfamily A, member 14
Synonyms: LOC383435
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 383435
Homologene: 138453
Sorl1
Name: sortilin-related receptor, LDLR class A repeats-containing
Synonyms: 2900010L19Rik, mSorLA, Sorla, LR11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20660
Homologene: 2336
Actl6a
Name: actin-like 6A
Synonyms: 2810432C06Rik, Actl6, ARP4, Baf53a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56456
Homologene: 55811
Elac2
Name: elaC ribonuclease Z 2
Synonyms: 1110017O07Rik, D11Wsu80e, tRNase Z(L)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68626
Homologene: 6403
Cenpk
Name: centromere protein K
Synonyms: Solt, C530004N04Rik, B130045K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 60411
VEGA: 13
Homologene: 11035
Tcerg1
Name: transcription elongation regulator 1 (CA150)
Synonyms: p144, Taf2s, 2900090C16Rik, ca150, 2410022J09Rik, Fbp28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 56070
Homologene: 4879
Zfp445
Name: zinc finger protein 445
Synonyms: ZNF168
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235682
VEGA: 9
Homologene: 27832
Phf10
Name: PHD finger protein 10
Synonyms: 1810055P05Rik, Baf45a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72057
Homologene: 10112
Peg10
Name: paternally expressed 10
Synonyms: HB-1, Rtl2, Mar2, Edr, MyEF-3 like, MyEF-3, MEF3L, Mart2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 170676
Homologene: 116067
Myof
Name: myoferlin
Synonyms: Fer1l3, E030042N20Rik, 2310051D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226101
VEGA: 19
HGNC: HGNC:3656
Homologene: 40882
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: C130041O22Rik, Zfh-4, Zfh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80892
Homologene: 23477
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Pico, Acz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26875
Homologene: 69111
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Txndc11
Name: thioredoxin domain containing 11
Synonyms: 2810408E11Rik, Txdc11, EFP1, EF-hand binding protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 106200
Homologene: 9301
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Pip4p1
Name: phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
Synonyms: Tmem55b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219024
Homologene: 10279
Itgb4
Name: integrin beta 4
Synonyms: CD104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192897
HGNC: HGNC:6158
Homologene: 179
Vmn2r110
Name: vomeronasal 2, receptor 110
Synonyms: EG224582
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224582
Homologene: 129678
Adamts2
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
Synonyms: hPCPNI, a disintegrin and metalloproteinase with thrombospondin repeats, procollagen N-proteinase, ADAM-TS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216725
HGNC: HGNC:218
Homologene: 8597
Bpifb9a
Name: BPI fold containing family B, member 9A
Synonyms: vomeromodulin, 4833413D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71425
Homologene: 128535
Il4ra
Name: interleukin 4 receptor, alpha
Synonyms: Il4r, IL-4 receptor alpha chain, CD124
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16190
HGNC: HGNC:6015
Homologene: 7784
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 435626
Homologene: 52359
Tcaf3
Name: TRPM8 channel-associated factor 3
Synonyms: Eapa2, Fam115e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 403088
Homologene: 74374
Myo5c
Name: myosin VC
Synonyms: 9130003O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208943
VEGA: 9
HGNC: HGNC:7604
Homologene: 135711
Vmn1r193
Name: vomeronasal 1 receptor 193
Synonyms: V1ri9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171259
Homologene: 110880
Fam171a1
Name: family with sequence similarity 171, member A1
Synonyms: 9630050M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269233
Homologene: 19521
Kif21b
Name: kinesin family member 21B
Synonyms: 2610511N21Rik, N-5 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16565
Homologene: 56868
Olfr1024
Name: olfactory receptor 1024
Synonyms: MOR197-1, GA_x6K02T2Q125-47384320-47383337
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257900
Homologene: 128271
Lrrc31
Name: leucine rich repeat containing 31
Synonyms: E230002P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 320352
Map2k1
Name: mitogen-activated protein kinase kinase 1
Synonyms: Prkmk1, Mek1, MAP kinase kinase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 26395
HGNC: HGNC:6840
Homologene: 2063
Sstr5
Name: somatostatin receptor 5
Synonyms: sst5, Smstr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20609
VEGA: 17
Homologene: 20287
Haus6
Name: HAUS augmin-like complex, subunit 6
Synonyms: D4Ertd27e, 6230416J20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230376
Homologene: 9760
Trim43b
Name: tripartite motif-containing 43B
Synonyms: Gm8269
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 666747
Homologene: 105432
Ptpn18
Name: protein tyrosine phosphatase, non-receptor type 18
Synonyms: FLP1, PTP-HSCF, HSCF, Ptpk1, PTP-K1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19253
HGNC: HGNC:9649
Homologene: 74971
Ebna1bp2
Name: EBNA1 binding protein 2
Synonyms: p40, Ebp2, B830003A16Rik, 1810014B19Rik, Nobp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69072
Homologene: 4969
Cd300lf
Name: CD300 molecule like family member F
Synonyms: IREM1, F730004D16Rik, DIgR2, LMIR3, IgSF13, CLM-1, Pigr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246746
Homologene: 51396
Pcdha5
Name: protocadherin alpha 5
Synonyms: Crnr6, Cnr6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12941
HGNC: HGNC:8671
Homologene: 49565
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 34,471,563 bp
  • A to T, chromosome 1 at 74,146,755 bp
  • C to T, chromosome 1 at 136,151,137 bp
  • T to A, chromosome 2 at 3,225,337 bp
  • T to C, chromosome 2 at 26,293,368 bp
  • T to C, chromosome 2 at 85,904,521 bp
  • T to C, chromosome 2 at 154,266,836 bp
  • T to A, chromosome 2 at 172,249,672 bp
  • G to C, chromosome 3 at 5,402,659 bp
  • A to G, chromosome 3 at 30,679,140 bp
  • G to A, chromosome 3 at 32,712,128 bp
  • A to T, chromosome 3 at 107,458,199 bp
  • T to A, chromosome 3 at 133,487,099 bp
  • T to A, chromosome 3 at 135,603,780 bp
  • A to G, chromosome 4 at 86,586,357 bp
  • T to C, chromosome 4 at 98,771,393 bp
  • A to T, chromosome 4 at 118,621,135 bp
  • T to A, chromosome 5 at 14,714,478 bp
  • A to G, chromosome 6 at 4,754,375 bp
  • A to G, chromosome 6 at 42,596,697 bp
  • T to A, chromosome 7 at 30,474,385 bp
  • T to C, chromosome 7 at 119,975,108 bp
  • T to C, chromosome 7 at 125,575,176 bp
  • T to A, chromosome 7 at 141,650,504 bp
  • A to T, chromosome 9 at 41,983,034 bp
  • T to A, chromosome 9 at 64,172,908 bp
  • C to T, chromosome 9 at 64,191,266 bp
  • A to G, chromosome 9 at 75,297,488 bp
  • A to T, chromosome 9 at 79,604,478 bp
  • C to T, chromosome 9 at 89,085,606 bp
  • C to T, chromosome 9 at 122,853,487 bp
  • T to C, chromosome 11 at 30,791,993 bp
  • T to G, chromosome 11 at 50,803,954 bp
  • G to T, chromosome 11 at 64,997,957 bp
  • G to A, chromosome 11 at 115,126,300 bp
  • C to T, chromosome 11 at 115,990,922 bp
  • A to G, chromosome 13 at 22,219,225 bp
  • A to G, chromosome 13 at 104,236,194 bp
  • A to G, chromosome 14 at 50,928,875 bp
  • A to T, chromosome 16 at 11,122,688 bp
  • A to C, chromosome 17 at 14,955,010 bp
  • A to G, chromosome 17 at 20,584,295 bp
  • T to A, chromosome 17 at 25,491,244 bp
  • T to C, chromosome 18 at 36,961,421 bp
  • T to A, chromosome 18 at 42,536,348 bp
  • A to T, chromosome 18 at 66,083,151 bp
  • T to C, chromosome 19 at 5,496,354 bp
  • A to G, chromosome 19 at 11,304,217 bp
  • T to C, chromosome 19 at 37,910,934 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5865 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044074-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.