Strain Name:
C57BL/6J-MtgxR5873Btlr
Stock Number:
044080-MU
Citation ID:
RRID:MMRRC_044080-MU
Other Names:
R5873 (G1)
Major Collection:

Gene Information

Pkd1
Name: polycystin 1, transient receptor poteintial channel interacting
Synonyms: polycystin-1, PC1, PC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18763
VEGA: 17
HGNC: HGNC:9008
Homologene: 250
Rc3h1
Name: RING CCCH (C3H) domains 1
Synonyms: roquin, 5730557L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381305
Homologene: 19036
Card11
Name: caspase recruitment domain family, member 11
Synonyms: 0610008L17Rik, BIMP3, CARMA1, 2410011D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 108723
Homologene: 13024
Tbx21
Name: T-box 21
Synonyms: Tblym, TBT1, T-bet, Tbet
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 57765
Homologene: 8353
Lrrn1
Name: leucine rich repeat protein 1, neuronal
Synonyms: NLRR-1, 2810047E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16979
Homologene: 32036
Esco2
Name: establishment of sister chromatid cohesion N-acetyltransferase 2
Synonyms: D030072L07Rik, 2410004I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71988
Homologene: 12432
Mybl1
Name: myeloblastosis oncogene-like 1
Synonyms: repro9, A-myb, G1-419-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17864
HGNC: HGNC:7547
Homologene: 32045
Matk
Name: megakaryocyte-associated tyrosine kinase
Synonyms: Csk homologous kinase, HYL, CHK, Ntk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17179
HGNC: HGNC:6906
Homologene: 48104
Asah2
Name: N-acylsphingosine amidohydrolase 2
Synonyms: neutral/alkaline ceramidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 54447
VEGA: 19
Homologene: 10310
Zranb2
Name: zinc finger, RAN-binding domain containing 2
Synonyms: Zis, Zfp265, Znf265
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 53861
Fry
Name: FRY microtubule binding protein
Synonyms: 9330186A19Rik, cg003
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320365
Homologene: 113770
Hmmr
Name: hyaluronan mediated motility receptor (RHAMM)
Synonyms: CD168, Rhamm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15366
HGNC: HGNC:5012
Homologene: 8271
Lta4h
Name: leukotriene A4 hydrolase
Synonyms: LTA4 hydrodase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16993
VEGA: 10
HGNC: HGNC:6710
Homologene: 6820
Abcc4
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Synonyms: D630049P08Rik, MRP4, MOAT-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239273
VEGA: 14
HGNC: HGNC:55
Homologene: 74563
Kpna1
Name: karyopherin (importin) alpha 1
Synonyms: m-importin-alpha-S1, NPI1, importin alpha 5, Rch2, mSRP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16646
HGNC: HGNC:6394
Homologene: 55642
Usp10
Name: ubiquitin specific peptidase 10
Synonyms: Uchrp, 2610014N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 22224
Homologene: 31294
Taf2
Name: TATA-box binding protein associated factor 2
Synonyms: 4732460C16Rik, 150kDa, CIF150, TAF2B, TAFII150
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 319944
VEGA: 15
Homologene: 31137
Prdm15
Name: PR domain containing 15
Synonyms: Zfp298, E130018M06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 114604
Homologene: 56941
Zkscan5
Name: zinc finger with KRAB and SCAN domains 5
Synonyms: Zfp95, hKraba1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22757
Homologene: 8734
Casc3
Name: cancer susceptibility candidate 3
Synonyms: Btz, Mln51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192160
Homologene: 7208
Cacna2d3
Name: calcium channel, voltage-dependent, alpha2/delta subunit 3
Synonyms: alpha2delta3, alpha 2 delta-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12294
Homologene: 74929
Pdia4
Name: protein disulfide isomerase associated 4
Synonyms: Erp72, ERp72, Cai, U48620
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12304
Homologene: 21020
Dnpep
Name: aspartyl aminopeptidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13437
HGNC: HGNC:2981
Homologene: 6110
Hnrnph3
Name: heterogeneous nuclear ribonucleoprotein H3
Synonyms: hnRNP 2H9, Hnrph3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 432467
HGNC: HGNC:5043
Homologene: 11012
Asxl3
Name: additional sex combs like 3, transcriptional regulator
Synonyms: C230079D11Rik, D430002O22Rik, D930044O18Rik, LOC381127
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 211961
Homologene: 19371
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Txndc11
Name: thioredoxin domain containing 11
Synonyms: EF-hand binding protein 1, 2810408E11Rik, EFP1, Txdc11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 106200
Homologene: 9301
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: Dnahcl1, LOC382552, 2810003K23Rik, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Synonyms: BC006779
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 229003
Homologene: 14118
C3ar1
Name: complement component 3a receptor 1
Synonyms: C3aR, anaphylatoxin C3a receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12267
HGNC: HGNC:1319
Homologene: 2992
C7
Name: complement component 7
Synonyms: LOC383055
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 109828
VEGA: 15
HGNC: HGNC:1346
Homologene: 489
Dock10
Name: dedicator of cytokinesis 10
Synonyms: ZIZ3, Jr5, Jr4, 9330153B10Rik, Zizimin3, A630054M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210293
Homologene: 45952
Cass4
Name: Cas scaffolding protein family member 4
Synonyms: F730031O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320664
Homologene: 75128
Vmn2r26
Name: vomeronasal 2, receptor 26
Synonyms: V2r1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 56552
Homologene: 135915
Nrp1
Name: neuropilin 1
Synonyms: Npn1, NP-1, NPN-1, Neuropilin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18186
HGNC: HGNC:8004
Homologene: 2876
Col14a1
Name: collagen, type XIV, alpha 1
Synonyms: 5730412L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12818
HGNC: HGNC:2191
Homologene: 18741
Adgre4
Name: adhesion G protein-coupled receptor E4
Synonyms: EGF-TM7, Emr4, Gpr127, D17Ertd479e, FIRE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 52614
VEGA: 17
Homologene: 64640
Evpl
Name: envoplakin
Synonyms: 210kDa protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14027
HGNC: HGNC:3503
Homologene: 1506
Rbak
Name: RB-associated KRAB zinc finger
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 57782
Homologene: 23287
Cyp2b23
Name: cytochrome P450, family 2, subfamily b, polypeptide 23
Synonyms: EG243881
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243881
Homologene: 117483
Vstm2a
Name: V-set and transmembrane domain containing 2A
Synonyms: Vstm2, 9330184N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 211739
Homologene: 17123
Gal3st2
Name: galactose-3-O-sulfotransferase 2
Synonyms: LOC381334
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381334
Homologene: 41471
Pdzd7
Name: PDZ domain containing 7
Synonyms: EG435601, Pdzk7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 100503041
Homologene: 129509
Olfr414
Name: olfactory receptor 414
Synonyms: GA_x6K02T2P20D-20749615-20748662, MOR103-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258756
Homologene: 17383
Cpt1b
Name: carnitine palmitoyltransferase 1b, muscle
Synonyms: Cpt1, M-CPT I, M-CPTI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12895
HGNC: HGNC:2329
Homologene: 22548
Ankk1
Name: ankyrin repeat and kinase domain containing 1
Synonyms: 9930020N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244859
VEGA: 9
Homologene: 18258
4930505A04Rik
Name: RIKEN cDNA 4930505A04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75087
Homologene: 18988
Exoc3l4
Name: exocyst complex component 3-like 4
Synonyms: 1600013K19Rik, 1200009I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 74190
VEGA: 12
Homologene: 41760
Tat
Name: tyrosine aminotransferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234724
Homologene: 37293
Olfr1371
Name: olfactory receptor 1371
Synonyms: MOR256-58, GA_x6K02T2QP88-3214035-3214970
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 276865
Ppp1r26
Name: protein phosphatase 1, regulatory subunit 26
Synonyms: LOC241289
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241289
Homologene: 49400
4921524L21Rik
Name: RIKEN cDNA 4921524L21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70901
VEGA: 18
Homologene: 78009
Cox10
Name: heme A:farnesyltransferase cytochrome c oxidase assembly factor 10
Synonyms: 2410004F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70383
HGNC: HGNC:2260
Homologene: 80170
Ppl
Name: periplakin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19041
VEGA: 16
HGNC: HGNC:9273
Homologene: 2026
Crybb2
Name: crystallin, beta B2
Synonyms: Aey2, betaB2-crystallin, Cryb-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12961
HGNC: HGNC:2398
Homologene: 420
Slc25a18
Name: solute carrier family 25 (mitochondrial carrier), member 18
Synonyms: 1500015I14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71803
Homologene: 57151
5330417H12Rik
Name: RIKEN cDNA 5330417H12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Krt28
Name: keratin 28
Synonyms: 4733401L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70843
Homologene: 124711
Galm
Name: galactose mutarotase
Synonyms: A530057M15Rik, aldose 1-epimerase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 319625
Homologene: 71795
Igkv4-90
Name: immunoglobulin kappa chain variable 4-90
Synonyms: Gm16906
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 434034
Gfy
Name: golgi-associated olfactory signaling regulator
Synonyms: Goofy, Gm581
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100039953
Homologene: 85248
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 9,685,665 bp
  • T to C, chromosome 1 at 75,315,143 bp
  • T to A, chromosome 1 at 80,574,138 bp
  • T to A, chromosome 1 at 93,873,750 bp
  • C to T, chromosome 1 at 160,959,501 bp
  • T to A, chromosome 1 at 174,430,782 bp
  • A to G, chromosome 2 at 28,451,605 bp
  • G to T, chromosome 2 at 172,426,768 bp
  • A to G, chromosome 2 at 181,234,028 bp
  • C to T, chromosome 3 at 157,536,383 bp
  • C to T, chromosome 5 at 113,065,893 bp
  • T to A, chromosome 5 at 140,908,638 bp
  • A to G, chromosome 5 at 143,173,711 bp
  • A to G, chromosome 5 at 145,220,394 bp
  • C to A, chromosome 5 at 150,378,885 bp
  • A to T, chromosome 6 at 47,808,176 bp
  • T to A, chromosome 6 at 68,807,469 bp
  • T to C, chromosome 6 at 107,568,975 bp
  • A to T, chromosome 6 at 120,786,281 bp
  • A to G, chromosome 6 at 122,850,422 bp
  • A to T, chromosome 6 at 124,061,674 bp
  • C to T, chromosome 7 at 26,675,006 bp
  • T to G, chromosome 7 at 45,177,580 bp
  • T to C, chromosome 7 at 107,624,768 bp
  • T to C, chromosome 8 at 109,991,949 bp
  • A to G, chromosome 8 at 119,947,092 bp
  • T to C, chromosome 8 at 128,468,377 bp
  • T to C, chromosome 9 at 49,415,896 bp
  • A to G, chromosome 10 at 63,019,391 bp
  • T to A, chromosome 10 at 81,260,129 bp
  • T to C, chromosome 10 at 93,469,190 bp
  • T to A, chromosome 11 at 16,258,044 bp
  • T to A, chromosome 11 at 30,426,220 bp
  • T to A, chromosome 11 at 40,707,700 bp
  • A to T, chromosome 11 at 52,213,353 bp
  • A to G, chromosome 11 at 64,071,686 bp
  • A to T, chromosome 11 at 97,114,648 bp
  • A to G, chromosome 11 at 98,821,444 bp
  • A to C, chromosome 11 at 99,366,890 bp
  • A to T, chromosome 11 at 116,234,432 bp
  • T to C, chromosome 11 at 118,056,897 bp
  • A to T, chromosome 12 at 111,423,416 bp
  • C to A, chromosome 14 at 29,720,934 bp
  • T to C, chromosome 14 at 65,824,191 bp
  • G to T, chromosome 14 at 118,526,290 bp
  • A to G, chromosome 15 at 5,005,235 bp
  • T to C, chromosome 15 at 55,038,422 bp
  • A to G, chromosome 15 at 55,445,786 bp
  • T to C, chromosome 15 at 89,420,728 bp
  • A to G, chromosome 16 at 5,106,049 bp
  • A to G, chromosome 16 at 11,075,205 bp
  • C to A, chromosome 16 at 32,751,295 bp
  • A to G, chromosome 16 at 36,014,228 bp
  • T to C, chromosome 16 at 97,808,689 bp
  • A to G, chromosome 17 at 24,569,830 bp
  • A to G, chromosome 17 at 55,852,282 bp
  • A to G, chromosome 17 at 80,138,103 bp
  • T to A, chromosome 18 at 6,630,167 bp
  • A to G, chromosome 18 at 22,516,085 bp
  • A to G, chromosome 19 at 32,003,682 bp
  • T to A, chromosome 19 at 45,027,949 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5873 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044080-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.