Strain Name:
C57BL/6J-MtgxR5883Btlr
Stock Number:
044086-MU
Citation ID:
RRID:MMRRC_044086-MU
Other Names:
R5883 (G1)
Major Collection:

Gene Information

Scarb1
Name: scavenger receptor class B, member 1
Synonyms: SR-BI, Cla-1, Cd36l1, Srb1, SRBI, Hlb398, D5Ertd460e, Chohd1, Hdlq1, Chohd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20778
HGNC: HGNC:1664
Homologene: 21132
Cacna1h
Name: calcium channel, voltage-dependent, T type, alpha 1H subunit
Synonyms: T-type Cav3.2, Cav3.2, alpha13.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 58226
HGNC: HGNC:1395
Homologene: 56913
Sox10
Name: SRY (sex determining region Y)-box 10
Synonyms: gt, Sox21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20665
VEGA: 15
Homologene: 5055
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNAPDcs, dxnph, slip, XRCC7, DNA-PKcs, DNA-PK, DOXNPH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Rad54l
Name: RAD54 like (S. cerevisiae)
Synonyms: RAD54
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19366
HGNC: HGNC:9826
Homologene: 48227
Cpne3
Name: copine III
Synonyms: CPN3, 5730450C07Rik, PRO1071, 5430428M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 70568
HGNC: HGNC:2316
Homologene: 20839
Cep290
Name: centrosomal protein 290
Synonyms: b2b1454Clo, b2b1752Clo, Kiaa, Nphp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216274
VEGA: 10
Homologene: 77213
Bop1
Name: block of proliferation 1
Synonyms: Erb1p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12181
VEGA: 15
Homologene: 6612
Larp1
Name: La ribonucleoprotein domain family, member 1
Synonyms: Larp, 1810024J12Rik, 3110040D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 73158
Homologene: 9089
Ubxn4
Name: UBX domain protein 4
Synonyms: 1300013G12Rik, Ubxd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67812
Homologene: 40962
Rif1
Name: replication timing regulatory factor 1
Synonyms: 5730435J01Rik, D2Ertd145e, 6530403D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 51869
Homologene: 41231
Ric1
Name: RAB6A GEF complex partner 1
Synonyms: C030046E11Rik, C130057E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226089
Homologene: 13806
Tox
Name: thymocyte selection-associated high mobility group box
Synonyms: 1700007F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 252838
Homologene: 8822
Islr2
Name: immunoglobulin superfamily containing leucine-rich repeat 2
Synonyms: B930052A04Rik, mbu-3, Linx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320563
VEGA: 9
Homologene: 10833
Ambn
Name: ameloblastin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11698
HGNC: HGNC:452
Homologene: 7625
D6Wsu163e
Name: DNA segment, Chr 6, Wayne State University 163, expressed
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 28040
HGNC: HGNC:1184
Homologene: 10685
Bub1b
Name: BUB1B, mitotic checkpoint serine/threonine kinase
Synonyms: BUBR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12236
HGNC: HGNC:1149
Homologene: 933
Akirin2
Name: akirin 2
Synonyms: 2700059D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 433693
Homologene: 9988
Marchf7
Name: membrane associated ring-CH-type finger 7
Synonyms: March7, Gtrgeo17, Axot
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 57438
Homologene: 10753
Ppip5k2
Name: diphosphoinositol pentakisphosphate kinase 2
Synonyms: Cfap160, Vip2, Hisppd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227399
Homologene: 49409
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 77505
Homologene: 131117
Bmf
Name: BCL2 modifying factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 171543
Homologene: 14130
Bmper
Name: BMP-binding endothelial regulator
Synonyms: Cv2, crossveinless-2, Crim3, CV-2, 3110056H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73230
VEGA: 9
Homologene: 12494
Med12l
Name: mediator complex subunit 12-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329650
Homologene: 43143
Taf5
Name: TATA-box binding protein associated factor 5
Synonyms: 6330528C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226182
VEGA: 19
Homologene: 5064
Vmn2r100
Name: vomeronasal 2, receptor 100
Synonyms: EG627537
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627537
Homologene: 129750
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Olfr209
Name: olfactory receptor 209
Synonyms: GA_x54KRFPKG5P-55590495-55589578, MOR182-6, MOR182-6, Olfr208, GA_x54KRFPKG5P-55580232-55579315
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 404311
Homologene: 133040
Lrp4
Name: low density lipoprotein receptor-related protein 4
Synonyms: mdig, Megf7, 6430526J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228357
HGNC: HGNC:6696
Homologene: 17964
Jakmip2
Name: janus kinase and microtubule interacting protein 2
Synonyms: 6430702L21Rik, D930046L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 76217
VEGA: 18
Homologene: 8866
Gm6264
Name: predicted gene 6264
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 102638435
Homologene: 139073
6430548M08Rik
Name: RIKEN cDNA 6430548M08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234797
Homologene: 8825
Aass
Name: aminoadipate-semialdehyde synthase
Synonyms: Lorsdh, LOR/SDH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 30956
Homologene: 4212
Has2
Name: hyaluronan synthase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 15117
HGNC: HGNC:4819
Homologene: 3892
Olfr531
Name: olfactory receptor 531
Synonyms: GA_x6K02T2PBJ9-42551260-42550346, MOR251-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258955
Zfp687
Name: zinc finger protein 687
Synonyms: 4931408L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 78266
Homologene: 10827
Krt90
Name: keratin 90
Synonyms: 4732456N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239673
Homologene: 72272
Hscb
Name: HscB iron-sulfur cluster co-chaperone
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100900
Homologene: 13945
Xkr5
Name: X-linked Kx blood group related 5
Synonyms: 5430438H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 319581
Homologene: 52219
Ano3
Name: anoctamin 3
Synonyms: B230324K02Rik, Tmem16c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228432
Homologene: 57147
Olfr490
Name: olfactory receptor 490
Synonyms: MOR204-17, GA_x6K02T2PBJ9-10617173-10616229
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258491
Homologene: 73955
Maip1
Name: matrix AAA peptidase interacting protein 1
Synonyms: 9430016H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68115
Homologene: 11565
Dlgap1
Name: DLG associated protein 1
Synonyms: DAP-1 beta, 4933422O14Rik, SAPAP1, GKAP/SAPAP, D17Bwg0511e, Sapap1, Gkap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224997
HGNC: HGNC:2905
Homologene: 31258
Cd84
Name: CD84 antigen
Synonyms: A130013D22Rik, SLAMF5, CDw84
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12523
HGNC: HGNC:1704
Homologene: 48249
Gm10309
Name: predicted gene 10309
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Pdzd9
Name: PDZ domain containing 9
Synonyms: 4930408O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67983
Homologene: 27865
Chil4
Name: chitinase-like 4
Synonyms: Ym2, Chi3l4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 104183
Homologene: 74931
Klk1b24
Name: kallikrein 1-related peptidase b24
Synonyms: Klk24, mGk-24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16617
HGNC: HGNC:6364
Homologene: 68141
Nt5c1a
Name: 5'-nucleotidase, cytosolic IA
Synonyms: Cn1a, LOC230718
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230718
Homologene: 57173
Rpl12
Name: ribosomal protein L12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269261
Homologene: 128047
Tmem128
Name: transmembrane protein 128
Synonyms: 2810021O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66309
Homologene: 11944
Ighv1-61
Name: immunoglobulin heavy variable 1-61
Synonyms: Gm16900
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 674018
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 57,407,101 bp
  • G to A, chromosome 1 at 85,171,182 bp
  • C to T, chromosome 1 at 97,707,810 bp
  • T to A, chromosome 1 at 128,256,130 bp
  • T to C, chromosome 1 at 171,872,838 bp
  • T to C, chromosome 2 at 32,962,524 bp
  • T to A, chromosome 2 at 52,105,639 bp
  • G to A, chromosome 2 at 60,234,442 bp
  • T to C, chromosome 2 at 91,488,433 bp
  • T to A, chromosome 2 at 110,880,864 bp
  • T to C, chromosome 2 at 113,030,292 bp
  • C to T, chromosome 2 at 118,546,966 bp
  • T to A, chromosome 2 at 118,609,882 bp
  • G to T, chromosome 3 at 59,091,468 bp
  • T to C, chromosome 3 at 95,012,044 bp
  • C to T, chromosome 3 at 106,210,570 bp
  • A to C, chromosome 4 at 6,697,444 bp
  • A to T, chromosome 4 at 19,552,314 bp
  • A to G, chromosome 4 at 34,565,256 bp
  • C to G, chromosome 4 at 116,099,046 bp
  • T to A, chromosome 4 at 123,216,256 bp
  • C to T, chromosome 5 at 38,266,541 bp
  • T to A, chromosome 5 at 88,467,829 bp
  • A to G, chromosome 5 at 110,839,578 bp
  • C to A, chromosome 5 at 125,340,907 bp
  • G to A, chromosome 6 at 23,072,994 bp
  • A to G, chromosome 6 at 126,966,916 bp
  • A to G, chromosome 7 at 44,190,363 bp
  • C to A, chromosome 7 at 105,720,504 bp
  • C to T, chromosome 7 at 108,286,244 bp
  • T to A, chromosome 7 at 120,668,553 bp
  • T to A, chromosome 7 at 140,400,188 bp
  • A to G, chromosome 8 at 18,940,790 bp
  • G to A, chromosome 8 at 120,145,641 bp
  • T to A, chromosome 9 at 23,406,674 bp
  • G to T, chromosome 9 at 58,198,715 bp
  • T to A, chromosome 10 at 100,523,399 bp
  • C to T, chromosome 11 at 58,042,299 bp
  • T to C, chromosome 12 at 115,359,563 bp
  • T to A, chromosome 15 at 56,668,063 bp
  • T to C, chromosome 15 at 76,454,849 bp
  • T to C, chromosome 15 at 79,156,263 bp
  • C to T, chromosome 15 at 101,553,219 bp
  • C to A, chromosome 16 at 15,715,914 bp
  • A to T, chromosome 16 at 59,361,715 bp
  • A to T, chromosome 17 at 19,523,524 bp
  • A to G, chromosome 17 at 25,376,922 bp
  • A to T, chromosome 17 at 70,517,013 bp
  • A to G, chromosome 17 at 86,498,757 bp
  • T to C, chromosome 18 at 43,581,994 bp
  • T to A, chromosome 19 at 29,595,989 bp
  • A to G, chromosome 19 at 47,067,789 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5883 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044086-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.