Strain Name:
C57BL/6J-MtgxR5917Btlr
Stock Number:
044114-MU
Citation ID:
RRID:MMRRC_044114-MU
Other Names:
R5917 (G1)
Major Collection:

Gene Information

Zfp423
Name: zinc finger protein 423
Synonyms: ataxia1, Roaz, Ebfaz, Zfp104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 94187
Homologene: 9010
Taok1
Name: TAO kinase 1
Synonyms: 2810468K05Rik, D130018F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216965
Homologene: 27041
Comp
Name: cartilage oligomeric matrix protein
Synonyms: TSP5, thrombospondin-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12845
HGNC: HGNC:2227
Homologene: 74
Dlgap4
Name: DLG associated protein 4
Synonyms: SAP90/PSD-95-associated protein 4, DAP4, PSD-95/SAP90 binding protein 4, Sapap4, WBP16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228836
Homologene: 8935
Resf1
Name: retroelement silencing factor 1
Synonyms: 2810474O19Rik, GET
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67246
Homologene: 19251
Ep300
Name: E1A binding protein p300
Synonyms: KAT3B, p300
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 328572
HGNC: HGNC:3373
Homologene: 1094
Dact1
Name: dishevelled-binding antagonist of beta-catenin 1
Synonyms: Dapper1, Frd1, Frodo, THYEX3, Frodo1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 59036
Homologene: 9613
Ascc2
Name: activating signal cointegrator 1 complex subunit 2
Synonyms: ASC1p100, 1700011I11Rik, 2610034L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75452
Homologene: 41774
Vars
Name: valyl-tRNA synthetase
Synonyms: G7a, Vars2, D17H6S56E, Bat6, Bat-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22321
Homologene: 4587
Limk1
Name: LIM-domain containing, protein kinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16885
HGNC: HGNC:6613
Homologene: 1738
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230895
Homologene: 15583
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: Sema6A-1, sema, A730020P05Rik, VIa, Semaq
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 20358
Homologene: 32426
Tle3
Name: transducin-like enhancer of split 3
Synonyms: Grg3a, 2610103N05Rik, Grg3b, ESG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21887
Homologene: 21059
Chst15
Name: carbohydrate sulfotransferase 15
Synonyms: 4631426J05Rik, GalNAcS-6ST, MAd5, MAd5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 77590
Homologene: 8908
Fcrls
Name: Fc receptor-like S, scavenger receptor
Synonyms: Msr2, IFGP2, Fcrh2, moFcRH2sc, 2810439C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 80891
Homologene: 57117
Il31ra
Name: interleukin 31 receptor A
Synonyms: GLM-R, GPL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218624
VEGA: 13
Homologene: 51395
Otor
Name: otoraplin
Synonyms: Fdp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 57329
HGNC: HGNC:8517
Homologene: 10600
Dhx29
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 29
Synonyms: E130202M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218629
VEGA: 13
Homologene: 10387
Amdhd1
Name: amidohydrolase domain containing 1
Synonyms: 1300019J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71761
Homologene: 14730
Lama2
Name: laminin, alpha 2
Synonyms: mer, merosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Pcdhb4
Name: protocadherin beta 4
Synonyms: Pcdhb5A, PcdhbD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93875
Homologene: 62176
Pcdh7
Name: protocadherin 7
Synonyms: BH-protocadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54216
HGNC: HGNC:8659
Homologene: 36101
Itga4
Name: integrin alpha 4
Synonyms: VLA-4 receptor, alpha 4 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16401
HGNC: HGNC:6140
Homologene: 37364
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Fbxo30
Name: F-box protein 30
Synonyms: 1700026A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71865
Homologene: 12959
Galnt11
Name: polypeptide N-acetylgalactosaminyltransferase 11
Synonyms: E430002F06Rik, A430075I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231050
Homologene: 11126
Strc
Name: stereocilin
Synonyms: DFNB16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 140476
Homologene: 15401
Ctss
Name: cathepsin S
Synonyms: Cat S
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 13040
HGNC: HGNC:2545
Homologene: 20867
Trank1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
Synonyms: A230061D21Rik, C030048J01Rik, Lba1, LOC235639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 320429
Homologene: 45845
Cryz
Name: crystallin, zeta
Synonyms: Sez9, quinone reductase, SEZ9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12972
HGNC: HGNC:2419
Homologene: 133907
Lgi4
Name: leucine-rich repeat LGI family, member 4
Synonyms: clp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243914
Homologene: 16408
Abcb5
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 5
Synonyms: 9230106F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 77706
HGNC: HGNC:46
Homologene: 83488
Map1a
Name: microtubule-associated protein 1 A
Synonyms: Mtap1, 6330416M19Rik, Mtap-1, Mtap1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17754
HGNC: HGNC:6835
Homologene: 1778
Rtl1
Name: retrotransposon Gaglike 1
Synonyms: Mart1, Mor1, Mar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 353326
VEGA: 12
Homologene: 120261
Proc
Name: protein C
Synonyms: PC, inactivator of coagulation factors Va, VIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 19123
VEGA: 18
HGNC: HGNC:9451
Homologene: 37288
Zfp521
Name: zinc finger protein 521
Synonyms: B930086A16Rik, Evi3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225207
VEGA: 18
Homologene: 9151
Matn2
Name: matrilin 2
Synonyms: Crtm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 17181
VEGA: 15
HGNC: HGNC:6908
Homologene: 20538
Pelo
Name: pelota mRNA surveillance and ribosome rescue factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 105083
VEGA: 13
HGNC: HGNC:8829
Homologene: 6835
Loxl1
Name: lysyl oxidase-like 1
Synonyms: LOXL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 16949
VEGA: 9
HGNC: HGNC:6665
Homologene: 4074
Mmrn1
Name: multimerin 1
Synonyms: 4921530G03Rik, Emilin4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 70945
HGNC: HGNC:7178
Homologene: 49134
Zfp788
Name: zinc finger protein 788
Synonyms: 2810426N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67607
Homologene: 137363
Zfp963
Name: zinc finger protein 963
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 620419
Homologene: 49795
Kcnt2
Name: potassium channel, subfamily T, member 2
Synonyms: E330038N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240776
Homologene: 16121
Olfr464
Name: olfactory receptor 464
Synonyms: MOR240-2, GA_x6K02T2PAEV-9555122-9554181
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258407
HGNC: HGNC:8293
Homologene: 44975
Ppp2r3a
Name: protein phosphatase 2, regulatory subunit B'', alpha
Synonyms: 3222402P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235542
HGNC: HGNC:9307
Homologene: 20595
Olfr1196
Name: olfactory receptor 1196
Synonyms: MOR225-5, GA_x6K02T2Q125-50181139-50180195
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258456
Homologene: 123770
Olfr13
Name: olfactory receptor 13
Synonyms: GA_x6K02T2P3E9-4384160-4383228, MOR261-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18310
Homologene: 27232
Zscan29
Name: zinc finger SCAN domains 29
Synonyms: Zfp690
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99334
Homologene: 17586
Prpsap2
Name: phosphoribosyl pyrophosphate synthetase-associated protein 2
Synonyms: A230054F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 212627
HGNC: HGNC:9467
Homologene: 2073
Tle2
Name: transducin-like enhancer of split 2
Synonyms: Grg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 21886
Homologene: 20693
Smpdl3a
Name: sphingomyelin phosphodiesterase, acid-like 3A
Synonyms: 0610010C24Rik, ASM3A, ASML3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 57319
Homologene: 4886
Clec4a4
Name: C-type lectin domain family 4, member a4
Synonyms: Dcir2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 474145
Homologene: 133910
Anks1b
Name: ankyrin repeat and sterile alpha motif domain containing 1B
Synonyms: C030032C09Rik, Gm10937, LOC380650, AIDA-1b, E530015N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 77531
Homologene: 51570
P2rx3
Name: purinergic receptor P2X, ligand-gated ion channel, 3
Synonyms: P2X3, 4930513E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228139
HGNC: HGNC:8534
Homologene: 1922
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 140,533,928 bp
  • A to T, chromosome 2 at 79,287,098 bp
  • A to T, chromosome 2 at 85,035,247 bp
  • A to T, chromosome 2 at 88,700,705 bp
  • G to T, chromosome 2 at 121,164,037 bp
  • A to G, chromosome 2 at 121,305,216 bp
  • T to A, chromosome 2 at 121,379,309 bp
  • A to G, chromosome 2 at 143,078,511 bp
  • A to G, chromosome 2 at 156,704,540 bp
  • T to A, chromosome 3 at 87,256,787 bp
  • A to G, chromosome 3 at 95,543,113 bp
  • T to A, chromosome 3 at 154,621,766 bp
  • G to A, chromosome 4 at 145,100,010 bp
  • C to A, chromosome 5 at 25,247,672 bp
  • T to C, chromosome 5 at 57,721,755 bp
  • A to G, chromosome 5 at 134,657,935 bp
  • C to T, chromosome 6 at 43,174,712 bp
  • T to C, chromosome 6 at 60,973,150 bp
  • A to T, chromosome 6 at 123,004,058 bp
  • T to C, chromosome 6 at 149,334,681 bp
  • C to T, chromosome 7 at 31,060,178 bp
  • A to G, chromosome 7 at 41,649,148 bp
  • T to A, chromosome 7 at 120,016,526 bp
  • A to G, chromosome 7 at 132,270,517 bp
  • A to T, chromosome 8 at 69,742,860 bp
  • T to A, chromosome 8 at 70,376,361 bp
  • C to A, chromosome 8 at 87,782,232 bp
  • A to G, chromosome 9 at 58,312,723 bp
  • A to G, chromosome 9 at 61,408,908 bp
  • A to T, chromosome 9 at 101,211,984 bp
  • A to G, chromosome 9 at 111,362,417 bp
  • A to T, chromosome 10 at 11,289,518 bp
  • A to G, chromosome 10 at 27,190,697 bp
  • T to A, chromosome 10 at 39,048,032 bp
  • T to A, chromosome 10 at 57,805,558 bp
  • T to C, chromosome 10 at 81,580,916 bp
  • C to T, chromosome 10 at 90,576,941 bp
  • T to C, chromosome 10 at 93,524,470 bp
  • T to C, chromosome 11 at 4,681,506 bp
  • C to T, chromosome 11 at 61,737,044 bp
  • A to T, chromosome 11 at 77,560,318 bp
  • A to T, chromosome 11 at 87,914,389 bp
  • G to T, chromosome 12 at 71,318,682 bp
  • T to G, chromosome 12 at 109,591,653 bp
  • T to A, chromosome 12 at 118,868,781 bp
  • A to G, chromosome 13 at 112,546,312 bp
  • A to G, chromosome 13 at 112,962,843 bp
  • A to G, chromosome 13 at 115,089,394 bp
  • T to A, chromosome 15 at 34,409,766 bp
  • T to A, chromosome 15 at 81,628,607 bp
  • C to A, chromosome 17 at 35,012,515 bp
  • T to A, chromosome 18 at 13,845,555 bp
  • T to A, chromosome 18 at 32,127,460 bp
  • T to A, chromosome 18 at 37,309,566 bp
  • T to G, chromosome 18 at 47,281,338 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5917 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044114-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.