Strain Name:
C57BL/6J-MtgxR5919Btlr
Stock Number:
044116-MU
Citation ID:
RRID:MMRRC_044116-MU
Other Names:
R5919 (G1)
Major Collection:

Gene Information

Ubn2
Name: ubinuclein 2
Synonyms: 6030408G03Rik, 2900060J04Rik, D130059P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320538
Homologene: 45564
Il17rd
Name: interleukin 17 receptor D
Synonyms: Sef, Sef-S, 2810004A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 171463
VEGA: 14
Homologene: 9717
Slc4a7
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 7
Synonyms: E430014N10Rik, NBC3, NBCn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218756
VEGA: 14
Homologene: 2680
Nup188
Name: nucleoporin 188
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227699
Homologene: 45683
Adgrl3
Name: adhesion G protein-coupled receptor L3
Synonyms: lectomedin 3, LEC3, D130075K09Rik, 5430402I23Rik, Lphn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319387
Homologene: 22878
Cop1
Name: COP1, E3 ubiquitin ligase
Synonyms: Cop1, Rfwd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26374
Homologene: 115565
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: A630086P08Rik, opm, b2b327Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 207304
VEGA: 12
Homologene: 9115
Zfp64
Name: zinc finger protein 64
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22722
Homologene: 7604
Gas2l3
Name: growth arrest-specific 2 like 3
Synonyms: LOC237436, 8430435B07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237436
VEGA: 10
Homologene: 18386
Fanci
Name: Fanconi anemia, complementation group I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 208836
Homologene: 49530
Ccdc15
Name: coiled-coil domain containing 15
Synonyms: A630039F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245902
VEGA: 9
Homologene: 28448
Phf11d
Name: PHD finger protein 11D
Synonyms: D14Ertd668e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219132
Homologene: 87807
Adgrl1
Name: adhesion G protein-coupled receptor L1
Synonyms: Lec2, lectomedin-2, 2900070I05Rik, Lphn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330814
Homologene: 8951
Crebbp
Name: CREB binding protein
Synonyms: CBP, KAT3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12914
HGNC: HGNC:2348
Homologene: 68393
Muc2
Name: mucin 2
Synonyms: 2010015E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17831
HGNC: HGNC:7512
Homologene: 136755
Angptl1
Name: angiopoietin-like 1
Synonyms: ANGPT3, ANGY, ARP1, ANG3, 2810039D03Rik, ANG-3, ANG3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72713
HGNC: HGNC:489
Homologene: 128467
Ms4a14
Name: membrane-spanning 4-domains, subfamily A, member 14
Synonyms: LOC383435
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 383435
Homologene: 138453
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Kif24
Name: kinesin family member 24
Synonyms: 4933425J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 109242
Homologene: 52346
Clstn1
Name: calsyntenin 1
Synonyms: calsyntenin-1, Cst-1, 1810034E21Rik, alcadein alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 65945
Homologene: 8814
Trerf1
Name: transcriptional regulating factor 1
Synonyms: Trep132, Trep-132, 9430096I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224829
Homologene: 14129
Ndufs1
Name: NADH:ubiquinone oxidoreductase core subunit S1
Synonyms: 9930026A05Rik, 5830412M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227197
HGNC: HGNC:7707
Homologene: 3670
Tmeff2
Name: transmembrane protein with EGF-like and two follistatin-like domains 2
Synonyms: 4832418D20Rik, 7630402F16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 56363
Homologene: 9417
Tmem178
Name: transmembrane protein 178
Synonyms: 2810417M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 68027
VEGA: 17
Homologene: 12226
Esrp1
Name: epithelial splicing regulatory protein 1
Synonyms: 2210008M09Rik, Rbm35a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 207920
Homologene: 9785
Ift172
Name: intraflagellar transport 172
Synonyms: wim, 4930553F24Rik, avc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67661
Homologene: 15202
Gm7102
Name: predicted gene 7102
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 633057
Myof
Name: myoferlin
Synonyms: 2310051D19Rik, E030042N20Rik, Fer1l3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226101
VEGA: 19
HGNC: HGNC:3656
Homologene: 40882
Mroh7
Name: maestro heat-like repeat family member 7
Synonyms: LOC381538, Gm1027, Heatr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381538
Homologene: 19633
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
2610507B11Rik
Name: RIKEN cDNA 2610507B11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72503
Homologene: 34730
Ccdc38
Name: coiled-coil domain containing 38
Synonyms: 4933417K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237465
Homologene: 52182
Kif17
Name: kinesin family member 17
Synonyms: N-4 kinesin, 5930435E01Rik, Kif17b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16559
Homologene: 5883
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241516
Homologene: 110349
Vmn2r2
Name: vomeronasal 2, receptor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 100125586
Homologene: 129753
Lrp4
Name: low density lipoprotein receptor-related protein 4
Synonyms: 6430526J12Rik, Megf7, mdig
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228357
HGNC: HGNC:6696
Homologene: 17964
Taar6
Name: trace amine-associated receptor 6
Synonyms: LOC215855
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215855
Homologene: 27874
Spata6
Name: spermatogenesis associated 6
Synonyms: Hash, 1700062C23Rik, KRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67946
Homologene: 10410
Gm8251
Name: predicted gene 8251
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 102636082
VEGA: 1
Homologene: 141149
Zfp787
Name: zinc finger protein 787
Synonyms: 2210018M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67109
Homologene: 18983
Hecw2
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Synonyms: D030049F17Rik, Nedl2, A730039N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329152
Homologene: 66192
Slc9a3
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3
Synonyms: NHE3, 9030624O13Rik, NHE-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105243
VEGA: 13
Homologene: 55804
Pelo
Name: pelota mRNA surveillance and ribosome rescue factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105083
VEGA: 13
HGNC: HGNC:8829
Homologene: 6835
Fam71e2
Name: family with sequence similarity 71, member E2
Synonyms: 4930401F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243822
Homologene: 89225
Dsel
Name: dermatan sulfate epimerase-like
Synonyms: 9330132E09Rik, DS-epi2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 319901
Homologene: 12964
Abcc3
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 3
Synonyms: 1700019L09Rik, MRP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76408
HGNC: HGNC:54
Homologene: 68364
Rars2
Name: arginyl-tRNA synthetase 2, mitochondrial
Synonyms: PRO1992, 1500002I10Rik, Rarsl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 109093
Homologene: 5707
Olfr1504
Name: olfactory receptor 1504
Synonyms: GA_x6K02T2RE5P-4223635-4222688, MOR212-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258627
Homologene: 45020
Aebp1
Name: AE binding protein 1
Synonyms: ACLP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11568
HGNC: HGNC:303
Homologene: 878
1700025G04Rik
Name: RIKEN cDNA 1700025G04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 69399
Homologene: 12776
Ndufaf1
Name: NADH:ubiquinone oxidoreductase complex assembly factor 1
Synonyms: CIA30, 2410001M24Rik, CGI-65
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69702
Homologene: 32289
Oasl1
Name: 2'-5' oligoadenylate synthetase-like 1
Synonyms: 7530414C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231655
HGNC: HGNC:8090
Homologene: 2769
Arl4d
Name: ADP-ribosylation factor-like 4D
Synonyms: Arl5, 1110036H21Rik, Arf4l, Arfl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 80981
HGNC: HGNC:656
Homologene: 1255
Camk2b
Name: calcium/calmodulin-dependent protein kinase II, beta
Synonyms: CaMK II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12323
HGNC: HGNC:1461
Homologene: 111050
6030458C11Rik
Name: RIKEN cDNA 6030458C11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 77877
VEGA: 15
Homologene: 10149
Rrp1
Name: ribosomal RNA processing 1
Synonyms: NNP-1, Nnp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18114
VEGA: 10
Vmn1r221
Name: vomeronasal 1 receptor 221
Synonyms: Gm11329
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 100312485
Homologene: 110880
S100a9
Name: S100 calcium binding protein A9 (calgranulin B)
Synonyms: MRP14, Cagb, BEE22, 60B8Ag, GAGB, L1Ag, p14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20202
Homologene: 2227
Trgv6
Name: T cell receptor gamma, variable 6
Synonyms: Tcrg-V6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 21640
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 44,056,986 bp
  • C to A, chromosome 1 at 51,132,152 bp
  • T to C, chromosome 1 at 53,937,090 bp
  • C to G, chromosome 1 at 63,143,832 bp
  • T to C, chromosome 1 at 111,860,253 bp
  • T to C, chromosome 1 at 151,915,498 bp
  • T to C, chromosome 1 at 156,858,546 bp
  • T to A, chromosome 1 at 159,319,724 bp
  • A to T, chromosome 2 at 30,339,894 bp
  • A to G, chromosome 2 at 82,992,609 bp
  • A to T, chromosome 2 at 91,473,207 bp
  • A to C, chromosome 2 at 119,660,228 bp
  • T to A, chromosome 2 at 168,926,499 bp
  • T to C, chromosome 3 at 64,137,302 bp
  • A to G, chromosome 3 at 90,695,188 bp
  • A to G, chromosome 4 at 11,344,146 bp
  • T to C, chromosome 4 at 34,657,232 bp
  • T to C, chromosome 4 at 41,394,477 bp
  • T to C, chromosome 4 at 106,694,312 bp
  • A to G, chromosome 4 at 111,779,208 bp
  • A to T, chromosome 4 at 138,269,891 bp
  • A to T, chromosome 4 at 149,635,246 bp
  • T to A, chromosome 5 at 31,260,662 bp
  • C to A, chromosome 5 at 81,646,570 bp
  • T to A, chromosome 5 at 114,928,270 bp
  • A to G, chromosome 6 at 38,491,488 bp
  • T to C, chromosome 7 at 4,770,386 bp
  • T to G, chromosome 7 at 6,132,835 bp
  • T to C, chromosome 7 at 79,444,738 bp
  • A to T, chromosome 7 at 141,641,570 bp
  • T to A, chromosome 7 at 141,694,928 bp
  • T to C, chromosome 8 at 45,026,873 bp
  • G to T, chromosome 8 at 83,932,610 bp
  • C to T, chromosome 9 at 37,320,396 bp
  • C to T, chromosome 9 at 79,602,298 bp
  • A to T, chromosome 10 at 23,985,270 bp
  • A to G, chromosome 10 at 78,405,588 bp
  • G to A, chromosome 10 at 89,417,055 bp
  • A to T, chromosome 10 at 93,578,838 bp
  • A to T, chromosome 11 at 5,871,421 bp
  • A to G, chromosome 11 at 5,979,718 bp
  • A to T, chromosome 11 at 78,289,350 bp
  • A to G, chromosome 11 at 94,357,306 bp
  • A to G, chromosome 11 at 101,667,136 bp
  • G to A, chromosome 12 at 51,769,072 bp
  • A to G, chromosome 13 at 19,190,612 bp
  • A to T, chromosome 13 at 23,217,296 bp
  • C to T, chromosome 13 at 74,158,740 bp
  • C to A, chromosome 13 at 115,089,309 bp
  • A to G, chromosome 14 at 14,791,092 bp
  • T to C, chromosome 14 at 27,096,044 bp
  • A to C, chromosome 14 at 59,356,263 bp
  • A to T, chromosome 15 at 12,823,668 bp
  • C to T, chromosome 16 at 4,108,127 bp
  • T to G, chromosome 17 at 47,323,282 bp
  • T to A, chromosome 17 at 80,989,758 bp
  • C to A, chromosome 19 at 11,314,297 bp
  • A to G, chromosome 19 at 13,887,845 bp
  • T to A, chromosome 19 at 38,024,370 bp
  • T to C, chromosome 19 at 61,175,469 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5919 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044116-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.