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Strain Name:
C57BL/6J-MtgxR5931Btlr/Mmmh
Stock Number:
044126-MU
Citation ID:
RRID:MMRRC_044126-MU
Other Names:
R5931 (G1)
Major Collection:

Strain Information

Atrn
Name: attractin
Synonyms: Mgca
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11990
HGNC: HGNC:885
Homologene: 22542
Cdh1
Name: cadherin 1
Synonyms: E-cadherin, Ecad, UM, uvomorulin, L-CAM, E-cad
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12550
HGNC: HGNC:1748
Homologene: 20917
Gabra6
Name: gamma-aminobutyric acid type A receptor subunit alpha 6
Synonyms: Gabra-6, alpha6, GABA-ARalpha6
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14399
HGNC: HGNC:4080
Homologene: 20220
Ppp1cb
Name: protein phosphatase 1 catalytic subunit beta
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19046
HGNC: HGNC:9282
Homologene: 37659
Ep400
Name: E1A binding protein p400
Synonyms: p400, mDomino, 1700020J09Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75560
Homologene: 38779
Lcmt1
Name: leucine carboxyl methyltransferase 1
Synonyms: Lcmt, LCMT-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 30949
Homologene: 41123
Tmem248
Name: transmembrane protein 248
Synonyms: G430067H08Rik, A930023A16Rik, 0610007L01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71667
Homologene: 9951
Prkca
Name: protein kinase C, alpha
Synonyms: Pkca
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18750
HGNC: HGNC:9393
Homologene: 55679
Uaca
Name: uveal autoantigen with coiled-coil domains and ankyrin repeats
Synonyms: nucling, 2700059D02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72565
VEGA: 9
Homologene: 74297
Fbxo15
Name: F-box protein 15
Synonyms: Fbx15, ecat3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 50764
VEGA: 18
Homologene: 17644
Fndc3a
Name: fibronectin type III domain containing 3A
Synonyms: 1700094E19Rik, F730017H24Rik, D14Ertd453e, Fndc3, sys
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319448
Homologene: 8952
Lpar6
Name: lysophosphatidic acid receptor 6
Synonyms: 2610302I02Rik, P2y5, P2ry5
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67168
Homologene: 55925
Gpbp1l1
Name: GC-rich promoter binding protein 1-like 1
Synonyms: 5330440M15Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77110
Homologene: 84840
Mcm3ap
Name: minichromosome maintenance complex component 3 associated protein
Synonyms: GANP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 54387
VEGA: 10
HGNC: HGNC:6946
Homologene: 2902
Eif2b2
Name: eukaryotic translation initiation factor 2B, subunit 2 beta
Synonyms: EIF-2Bbeta, EIF2B
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217715
HGNC: HGNC:3258
Homologene: 6507
Clca2
Name: chloride channel accessory 2
Synonyms: Clca5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229933
HGNC: HGNC:2016
Homologene: 4765
Rph3a
Name: rabphilin 3A
Synonyms: 2900002P20Rik, Doc2 family
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19894
Homologene: 7921
Rfx2
Name: regulatory factor X, 2 (influences HLA class II expression)
Synonyms: 5430432H19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19725
VEGA: 17
HGNC: HGNC:9983
Homologene: 30980
Ern1
Name: endoplasmic reticulum to nucleus signalling 1
Synonyms: 9030414B18Rik, Ire1p, Ire1alpha, Ire1a
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78943
HGNC: HGNC:3449
Homologene: 55580
Hoxa3
Name: homeobox A3
Synonyms: Hox-1.5, Mo-10
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 15400
HGNC: HGNC:5104
Homologene: 40725
Igha
Name: immunoglobulin heavy constant alpha
Synonyms: IgA, Igh-2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238447
Dgcr2
Name: DiGeorge syndrome critical region gene 2
Synonyms: Dgcr2, Idd, Lan, Sez12, Dgsc, DGS-C, 9930034O06Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13356
HGNC: HGNC:2845
Homologene: 31292
Lrrtm4
Name: leucine rich repeat transmembrane neuronal 4
Synonyms: 7530419J18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243499
Homologene: 11807
Vps4b
Name: vacuolar protein sorting 4B
Synonyms: Skd1, 8030489C12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20479
Homologene: 37976
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, 2610100B16Rik, Odz3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23965
Homologene: 22673
Hs1bp3
Name: HCLS1 binding protein 3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 58240
VEGA: 12
Homologene: 10980
Ythdc2
Name: YTH domain containing 2
Synonyms: 3010002F02Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240255
Homologene: 11265
Plxna2
Name: plexin A2
Synonyms: OCT, Plxn2, 2810428A13Rik, PlexA2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18845
HGNC: HGNC:9100
Homologene: 56427
Pnkd
Name: paroxysmal nonkinesiogenic dyskinesia
Synonyms: 2210013N15Rik, 2810403H05Rik, Brp17
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56695
HGNC: HGNC:9153
Homologene: 75045
Nphp3
Name: nephronophthisis 3 (adolescent)
Synonyms: D330020E01Rik, pcy, nephrocystin 3, 3632410F03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74025
HGNC: HGNC:7907
Homologene: 32697
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: Mdnah5, b2b1537Clo, b2b1565Clo, b2b1154Clo, b2b1134Clo, Dnahc5, b2b3491Clo
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, syne-2, D12Ertd777e, 6820443O06Rik, Nesp2g, Cpfl8, diminished cone electroretinogram, dice
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319565
Homologene: 56700
Dgkg
Name: diacylglycerol kinase, gamma
Synonyms: Dagk3, E430001K23Rik, 2900055E17Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 110197
HGNC: HGNC:2853
Homologene: 1029
Stk31
Name: serine threonine kinase 31
Synonyms: C330007K24Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 77485
Homologene: 12677
Trim69
Name: tripartite motif-containing 69
Synonyms: 4921519C19Rik, Trif, Rnf36
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70928
Homologene: 18827
Dbt
Name: dihydrolipoamide branched chain transacylase E2
Synonyms: BCKAD E2, D3Wsu60e, dihydrolipoyl transacylase, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 13171
HGNC: HGNC:2698
Homologene: 1444
Dnaaf9
Name: dynein axonemal assembly factor 9
Synonyms: 4930402H24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228602
Homologene: 12623
Egflam
Name: EGF-like, fibronectin type III and laminin G domains
Synonyms: nectican, pikachurin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 268780
Homologene: 65044
Ermp1
Name: endoplasmic reticulum metallopeptidase 1
Synonyms: D19Ertd410e, D19Wsu12e, b2b2633Clo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226090
Homologene: 121891
C4b
Name: complement C4B (Chido blood group)
Synonyms: Ss, C4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12268
Homologene: 36030
Wnk4
Name: WNK lysine deficient protein kinase 4
Synonyms: 2010002J11Rik, Prkwnk4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69847
Homologene: 13020
Cyld
Name: CYLD lysine 63 deubiquitinase
Synonyms: CYLD1, 2010013M14Rik, C130039D01Rik, 2900009M21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74256
HGNC: HGNC:2584
Homologene: 9069
Chrna1
Name: cholinergic receptor nicotinic alpha 1 subunit
Synonyms: Achr-1, Acra
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11435
HGNC: HGNC:1955
Homologene: 59
Sp100
Name: nuclear antigen Sp100
Synonyms: A430075G10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20684
Homologene: 86761
Pnma8a
Name: PNMA family member 8A
Synonyms: 0710005I19Rik, 4930488B01Rik, Pnmal1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71691
Homologene: 10073
Tmcc2
Name: transmembrane and coiled-coil domains 2
Synonyms: 1110063G11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68875
Homologene: 8905
Pelo
Name: pelota mRNA surveillance and ribosome rescue factor
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105083
VEGA: 13
HGNC: HGNC:8829
Homologene: 6835
Ttc28
Name: tetratricopeptide repeat domain 28
Synonyms: 2310015L07Rik, TPRBK
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 209683
Homologene: 41023
Or7g33
Name: olfactory receptor family 7 subfamily G member 33
Synonyms: GA_x6K02T2PVTD-13277703-13276786, MOR154-1, Olfr853
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258908
HGNC: HGNC:8466
Homologene: 133623
Scel
Name: sciellin
Synonyms: 9230114I02Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 64929
VEGA: 14
Homologene: 2850
Or8b40
Name: olfactory receptor family 8 subfamily B member 40
Synonyms: GA_x6K02T2PVTD-31795028-31795957, MOR162-2, Olfr889
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258475
Homologene: 138311
Hook2
Name: hook microtubule tethering protein 2
Synonyms: A630054I03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 170833
Homologene: 8332
4930590J08Rik
Name: RIKEN cDNA 4930590J08 gene
Synonyms: LOC381798
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 381798
Homologene: 49985
Paqr7
Name: progestin and adipoQ receptor family member VII
Synonyms: PGLP, 2310021M12Rik, mPR, Mpra
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 71904
Homologene: 12420
Klra4
Name: killer cell lectin-like receptor, subfamily A, member 4
Synonyms: Chok, Ly49d, ly49r129
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16635
Homologene: 110821
Plp2rt
Name: proteolipid protein 2, retrotransposed
Synonyms: Gm6169, Prp2rt
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 620648
VEGA: 13
HGNC: HGNC:9087
Tor3a
Name: torsin family 3, member A
Synonyms: Adir
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 30935
Homologene: 23359
Pcdha4
Name: protocadherin alpha 4
Synonyms: Cnr1, Crnr1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12936
HGNC: HGNC:8670
Homologene: 130626
Ccdc67
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Lrrc16b
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 74,350,674 bp
  • C to T, chromosome 1 at 85,679,083 bp
  • T to C, chromosome 1 at 106,777,335 bp
  • TTGCTGCTGCTGCTGCTGC to TTGCTGCTGCTGCTGC, chromosome 1 at 132,357,755 bp
  • T to C, chromosome 1 at 156,656,487 bp
  • A to T, chromosome 1 at 194,810,870 bp
  • C to T, chromosome 2 at 73,568,100 bp
  • A to T, chromosome 2 at 122,178,594 bp
  • G to A, chromosome 2 at 130,814,189 bp
  • A to T, chromosome 2 at 130,933,436 bp
  • C to T, chromosome 2 at 181,330,815 bp
  • A to T, chromosome 3 at 116,523,425 bp
  • A to C, chromosome 3 at 145,092,125 bp
  • T to C, chromosome 4 at 116,590,260 bp
  • A to C, chromosome 4 at 134,507,720 bp
  • T to A, chromosome 5 at 32,483,466 bp
  • A to G, chromosome 5 at 110,735,520 bp
  • C to T, chromosome 5 at 111,085,109 bp
  • T to C, chromosome 5 at 120,963,873 bp
  • T to A, chromosome 5 at 130,229,508 bp
  • A to G, chromosome 6 at 49,469,302 bp
  • G to A, chromosome 6 at 52,172,588 bp
  • A to G, chromosome 6 at 80,021,739 bp
  • A to T, chromosome 6 at 91,919,115 bp
  • C to T, chromosome 6 at 130,053,053 bp
  • C to A, chromosome 7 at 16,960,884 bp
  • A to G, chromosome 7 at 123,421,616 bp
  • A to T, chromosome 8 at 48,646,498 bp
  • G to T, chromosome 8 at 84,995,746 bp
  • A to G, chromosome 8 at 88,729,842 bp
  • T to C, chromosome 8 at 106,666,332 bp
  • T to C, chromosome 9 at 15,561,322 bp
  • A to T, chromosome 9 at 19,537,333 bp
  • A to G, chromosome 9 at 38,116,374 bp
  • T to C, chromosome 9 at 60,872,012 bp
  • T to A, chromosome 9 at 104,020,746 bp
  • T to C, chromosome 10 at 76,471,166 bp
  • G to A, chromosome 11 at 42,307,441 bp
  • A to G, chromosome 11 at 101,261,221 bp
  • A to G, chromosome 11 at 106,426,873 bp
  • T to G, chromosome 11 at 108,014,310 bp
  • C to A, chromosome 12 at 8,341,915 bp
  • T to A, chromosome 12 at 76,008,865 bp
  • C to T, chromosome 12 at 85,222,787 bp
  • T to A, chromosome 12 at 113,260,090 bp
  • A to G, chromosome 13 at 97,099,197 bp
  • T to A, chromosome 13 at 115,088,843 bp
  • A to C, chromosome 14 at 55,498,940 bp
  • A to G, chromosome 14 at 57,696,131 bp
  • A to T, chromosome 14 at 72,568,867 bp
  • A to G, chromosome 14 at 73,238,928 bp
  • T to A, chromosome 14 at 103,605,624 bp
  • G to A, chromosome 15 at 7,243,857 bp
  • A to T, chromosome 15 at 28,453,279 bp
  • T to A, chromosome 16 at 17,857,309 bp
  • G to A, chromosome 16 at 22,558,038 bp
  • A to T, chromosome 16 at 32,794,574 bp
  • A to G, chromosome 17 at 34,729,193 bp
  • G to A, chromosome 17 at 56,780,778 bp
  • A to T, chromosome 18 at 36,954,755 bp
  • T to A, chromosome 18 at 44,872,956 bp
  • T to A, chromosome 18 at 84,981,125 bp
  • C to G, chromosome 19 at 29,615,729 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5931 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044126-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.