Strain Name:
C57BL/6J-MtgxR5943Btlr
Stock Number:
044135-MU
Citation ID:
RRID:MMRRC_044135-MU
Other Names:
R5943 (G1)
Major Collection:

Gene Information

Dhrs3
Name: dehydrogenase/reductase (SDR family) member 3
Synonyms: retSDR1, Rsdr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 20148
Homologene: 20994
Strn
Name: striatin, calmodulin binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268980
Homologene: 2380
Tsnax
Name: translin-associated factor X
Synonyms: Trax
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 53424
Homologene: 4374
Cdc6
Name: cell division cycle 6
Synonyms: cell division cycle 18 homolog (S.pombe)-like, CDC18L, CDC18(S.pombe)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 23834
HGNC: HGNC:1744
Homologene: 68172
Dido1
Name: death inducer-obliterator 1
Synonyms: DIO-1, 6720461J16Rik, D130048F08Rik, Datf1, dido, C130092D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 23856
HGNC: HGNC:2680
Homologene: 34139
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, 4833432B22Rik, D4Abb1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100019
Homologene: 39689
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, Lek1, mitosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Fas
Name: Fas (TNF receptor superfamily member 6)
Synonyms: CD95, APO-1, TNFR6, Tnfrsf6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14102
VEGA: 19
Homologene: 27
Wwc2
Name: WW, C2 and coiled-coil domain containing 2
Synonyms: D8Ertd594e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 52357
Homologene: 32618
Adcy1
Name: adenylate cyclase 1
Synonyms: AC1, I-AC, D11Bwg1392e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432530
HGNC: HGNC:232
Homologene: 41419
Fezf1
Name: Fez family zinc finger 1
Synonyms: Zfp312-like, Fez, 3110069A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73191
Homologene: 19252
Pxylp1
Name: 2-phosphoxylose phosphatase 1
Synonyms: 9430094M07Rik, C130099A20Rik, Acpl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235534
Homologene: 15931
Pcca
Name: propionyl-Coenzyme A carboxylase, alpha polypeptide
Synonyms: C79630
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110821
HGNC: HGNC:8653
Homologene: 236
Man2a1
Name: mannosidase 2, alpha 1
Synonyms: Mana-2, Mana2, Map-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17158
HGNC: HGNC:6824
Homologene: 1777
Yme1l1
Name: YME1-like 1 (S. cerevisiae)
Synonyms: Ftsh, ATP-dependent metalloprotease FtsH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27377
Homologene: 31996
Ankrd26
Name: ankyrin repeat domain 26
Synonyms: 5730521P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232339
Homologene: 45968
Mtus1
Name: mitochondrial tumor suppressor 1
Synonyms: MD44, MTSG1, Atip1, B430305I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102103
Homologene: 100292
Itpkc
Name: inositol 1,4,5-trisphosphate 3-kinase C
Synonyms: 9130023N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233011
Homologene: 11868
Col4a4
Name: collagen, type IV, alpha 4
Synonyms: [a]4(IV), E130010M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12829
HGNC: HGNC:2206
Homologene: 20071
Cp
Name: ceruloplasmin
Synonyms: D3Ertd555e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12870
HGNC: HGNC:2295
Homologene: 75
Acaa2
Name: acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)
Synonyms: 0610011L04Rik, D18Ertd240e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 52538
VEGA: 18
HGNC: HGNC:83
Homologene: 4456
Clcn1
Name: chloride channel, voltage-sensitive 1
Synonyms: SMCC1, Clc-1, Clc1, NMF355, nmf355
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12723
HGNC: HGNC:2019
Homologene: 63
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Pcnx4
Name: pecanex homolog 4
Synonyms: 1810048J11Rik, Pcnxl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 67708
VEGA: 12
Homologene: 23366
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mass1, Mgr1, Gpr98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110789
Homologene: 19815
Psmb9
Name: proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
Synonyms: Lmp-2, Lmp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16912
HGNC: HGNC:9546
Homologene: 2094
Trim14
Name: tripartite motif-containing 14
Synonyms: 5830400N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74735
Homologene: 13241
Dnase1l2
Name: deoxyribonuclease 1-like 2
Synonyms: 4733401H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66705
HGNC: HGNC:2958
Homologene: 74391
Vmn2r70
Name: vomeronasal 2, receptor 70
Synonyms: EG620835
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 670940
Homologene: 115466
Duox1
Name: dual oxidase 1
Synonyms: LNOX1, 9930101G15Rik, NOXEF1, THOX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99439
HGNC: HGNC:3062
Homologene: 68136
Adamts9
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
Synonyms: 1810011L16Rik, E030027K14Rik, 8430403M15Rik, Mhdaund4, Gsfund3, UND3, Mhdaund3, UND4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 101401
Homologene: 18821
Eya2
Name: EYA transcriptional coactivator and phosphatase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14049
HGNC: HGNC:3520
Homologene: 40711
Ccdc150
Name: coiled-coil domain containing 150
Synonyms: 4930511H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78016
Homologene: 15814
Coq8b
Name: coenzyme Q8B
Synonyms: 0610012P18Rik, Adck4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76889
Homologene: 86731
Wdr66
Name: WD repeat domain 66
Synonyms: 4930415N18Rik, 4933428F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269701
Homologene: 16964
Myo3b
Name: myosin IIIB
Synonyms: A430065P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329421
Homologene: 51393
Pnmal2
Name: PNMA-like 2
Synonyms: EG434128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434128
Homologene: 35491
Gnptab
Name: N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
Synonyms: EG432486
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 432486
Homologene: 32576
Gsdma
Name: gasdermin A
Synonyms: H312E, Gsdm, Gsdm1, Gsdma1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 57911
Homologene: 10962
Krtap5-1
Name: keratin associated protein 5-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 50774
Acap3
Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
Synonyms: Kiaa1716-hp, Centb5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 140500
Homologene: 23708
Rnf43
Name: ring finger protein 43
Synonyms: 4732452J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 207742
Homologene: 37742
Aars2
Name: alanyl-tRNA synthetase 2, mitochondrial
Synonyms: Aarsl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224805
VEGA: 17
Homologene: 56897
Zc3h10
Name: zinc finger CCCH type containing 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103284
Homologene: 13114
Radil
Name: Ras association and DIL domains
Synonyms: D930005D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231858
Homologene: 77648
Pacsin1
Name: protein kinase C and casein kinase substrate in neurons 1
Synonyms: A830061D09Rik, Syndapin I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 23969
HGNC: HGNC:8570
Homologene: 22674
Olfr669
Name: olfactory receptor 669
Synonyms: GA_x6K02T2PBJ9-7567376-7568329, MOR34-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259045
Homologene: 72057
Cd163
Name: CD163 antigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 93671
HGNC: HGNC:1631
Homologene: 128811
Vmn1r198
Name: vomeronasal 1 receptor 198
Synonyms: V1ri3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171254
Homologene: 110880
Lrriq3
Name: leucine-rich repeats and IQ motif containing 3
Synonyms: 4930438B07Rik, 4930511J15Rik, 4933403H06Rik, Lrrc44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74435
Homologene: 23668
Olfr1504
Name: olfactory receptor 1504
Synonyms: GA_x6K02T2RE5P-4223635-4222688, MOR212-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258627
Homologene: 45020
Sult3a1
Name: sulfotransferase family 3A, member 1
Synonyms: Sultx2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 57430
VEGA: 10
Homologene: 111031
Nckipsd
Name: NCK interacting protein with SH3 domain
Synonyms: WISH, SPIN90, AF3P21, ORF1, DIP1, Wasbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80987
Homologene: 9514
Dcst1
Name: DC-STAMP domain containing 1
Synonyms: A330106H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77772
Homologene: 14981
Kank3
Name: KN motif and ankyrin repeat domains 3
Synonyms: 0610013D04Rik, D17Ertd288e, Ankrd47
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 80880
Homologene: 12749
Zc2hc1c
Name: zinc finger, C2HC-type containing 1C
Synonyms: 2810002I04Rik, Fam164c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 72350
Homologene: 23461
Sp5
Name: trans-acting transcription factor 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 64406
Homologene: 11190
Clrn2
Name: clarin 2
Synonyms: EG624224, mpc169H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 624224
Homologene: 84057
Acad8
Name: acyl-Coenzyme A dehydrogenase family, member 8
Synonyms: 2310016C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66948
HGNC: HGNC:87
Homologene: 8662
Zfp825
Name: zinc finger protein 825
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 235956
Mri1
Name: methylthioribose-1-phosphate isomerase 1
Synonyms: 2410018C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67873
Homologene: 7160
Hoxd3
Name: homeobox D3
Synonyms: Hox-5.5, Hox-4.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 15434
HGNC: HGNC:5137
Homologene: 5034
Gldn
Name: gliomedin
Synonyms: Crlg2, CRG-L2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235379
Homologene: 14529
Atp6v1fnb
Name: Atp6v1f neighbor
Synonyms: Gm9047
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 668210
Homologene: 89367
Pcdhga8
Name: protocadherin gamma subfamily A, 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93716
HGNC: HGNC:8706
Homologene: 57162
Gm15800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 54,300,367 bp
  • A to G, chromosome 1 at 82,525,016 bp
  • A to T, chromosome 1 at 189,659,969 bp
  • G to T, chromosome 2 at 23,168,330 bp
  • G to A, chromosome 2 at 70,286,941 bp
  • A to T, chromosome 2 at 70,475,315 bp
  • A to G, chromosome 2 at 74,746,829 bp
  • A to G, chromosome 2 at 76,968,436 bp
  • G to A, chromosome 2 at 122,333,435 bp
  • A to G, chromosome 2 at 165,724,689 bp
  • A to T, chromosome 2 at 180,661,882 bp
  • A to T, chromosome 3 at 19,964,306 bp
  • A to T, chromosome 3 at 89,356,411 bp
  • A to G, chromosome 3 at 155,163,950 bp
  • T to C, chromosome 4 at 32,678,330 bp
  • T to C, chromosome 4 at 46,522,136 bp
  • A to T, chromosome 4 at 144,919,976 bp
  • T to C, chromosome 4 at 155,899,422 bp
  • A to T, chromosome 5 at 45,463,719 bp
  • A to T, chromosome 5 at 121,322,294 bp
  • A to G, chromosome 5 at 123,286,357 bp
  • A to G, chromosome 5 at 142,485,458 bp
  • T to A, chromosome 6 at 23,246,949 bp
  • T to A, chromosome 6 at 29,471,909 bp
  • T to A, chromosome 6 at 42,292,966 bp
  • T to C, chromosome 6 at 92,903,786 bp
  • A to T, chromosome 6 at 118,505,746 bp
  • T to C, chromosome 6 at 124,329,602 bp
  • T to C, chromosome 7 at 16,946,437 bp
  • T to A, chromosome 7 at 27,212,979 bp
  • T to A, chromosome 7 at 27,234,003 bp
  • T to C, chromosome 7 at 85,565,991 bp
  • T to A, chromosome 7 at 104,938,643 bp
  • A to G, chromosome 7 at 142,297,051 bp
  • T to C, chromosome 8 at 41,084,265 bp
  • T to C, chromosome 8 at 47,990,102 bp
  • A to T, chromosome 8 at 84,254,319 bp
  • C to A, chromosome 8 at 125,024,539 bp
  • A to G, chromosome 9 at 26,999,444 bp
  • T to G, chromosome 9 at 54,338,437 bp
  • A to G, chromosome 9 at 96,839,150 bp
  • C to T, chromosome 9 at 108,812,236 bp
  • A to G, chromosome 10 at 33,866,641 bp
  • T to C, chromosome 10 at 88,433,514 bp
  • C to A, chromosome 10 at 128,545,527 bp
  • T to C, chromosome 11 at 7,161,337 bp
  • G to A, chromosome 11 at 87,731,735 bp
  • A to T, chromosome 11 at 98,673,026 bp
  • T to C, chromosome 11 at 98,920,763 bp
  • A to G, chromosome 12 at 72,579,458 bp
  • C to A, chromosome 12 at 85,289,709 bp
  • T to A, chromosome 13 at 22,355,197 bp
  • T to C, chromosome 13 at 74,480,888 bp
  • T to C, chromosome 13 at 81,386,866 bp
  • T to A, chromosome 14 at 122,658,776 bp
  • C to T, chromosome 17 at 24,442,747 bp
  • T to C, chromosome 17 at 27,706,071 bp
  • G to T, chromosome 17 at 33,818,401 bp
  • T to C, chromosome 17 at 34,184,291 bp
  • C to A, chromosome 17 at 45,517,711 bp
  • A to G, chromosome 17 at 64,625,380 bp
  • C to A, chromosome 17 at 78,669,847 bp
  • A to G, chromosome 18 at 37,816,512 bp
  • A to G, chromosome 18 at 74,792,382 bp
  • C to T, chromosome 19 at 13,887,752 bp
  • T to G, chromosome 19 at 34,320,587 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5943 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044135-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.