Strain Name:
C57BL/6J-MtgxR5952Btlr
Stock Number:
044142-MU
Citation ID:
RRID:MMRRC_044142-MU
Other Names:
R5952 (G1)
Major Collection:

Gene Information

Myh9
Name: myosin, heavy polypeptide 9, non-muscle
Synonyms: D0Jmb2, E030044M24Rik, NMHC II-A, Myhn-1, Myhn1, myosin IIA, Fltn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17886
HGNC: HGNC:7579
Homologene: 129835
Lamb3
Name: laminin, beta 3
Synonyms: nicein, 125kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16780
HGNC: HGNC:6490
Homologene: 191
Epb41l1
Name: erythrocyte membrane protein band 4.1 like 1
Synonyms: 4.1N, Epb4.1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13821
HGNC: HGNC:3378
Homologene: 8126
Ptprk
Name: protein tyrosine phosphatase, receptor type, K
Synonyms: PTPk, RPTPkappa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19272
VEGA: 10
HGNC: HGNC:9674
Homologene: 55693
Ddx23
Name: DEAD box helicase 23
Synonyms: 4921506D17Rik, 3110082M05Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 74351
Homologene: 3542
Hira
Name: histone cell cycle regulator
Synonyms: Tuple1, D16Ertd95e, Gm15797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 15260
HGNC: HGNC:4916
Homologene: 48172
Map4k4
Name: mitogen-activated protein kinase kinase kinase kinase 4
Synonyms: Nik, 9430080K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26921
HGNC: HGNC:6866
Homologene: 7442
Rps6kc1
Name: ribosomal protein S6 kinase polypeptide 1
Synonyms: RPK118, B130003F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320119
Homologene: 8244
Rnf169
Name: ring finger protein 169
Synonyms: 2900057K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 108937
Homologene: 47510
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: Tweek, FSA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229227
Homologene: 52105
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ank-3, Ankyrin-3, AnkG, 2900054D09Rik, Ankyrin-G
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Arid4a
Name: AT rich interactive domain 4A (RBP1-like)
Synonyms: A630067N03Rik, Rbbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238247
HGNC: HGNC:9885
Homologene: 11303
Tacc1
Name: transforming, acidic coiled-coil containing protein 1
Synonyms: 4833447E04Rik, Tacc1, B230378H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 320165
Homologene: 4575
Jcad
Name: junctional cadherin 5 associated
Synonyms: 9430020K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240185
VEGA: 18
Homologene: 19370
Fezf1
Name: Fez family zinc finger 1
Synonyms: Zfp312-like, Fez, 3110069A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73191
Homologene: 19252
Neurod6
Name: neurogenic differentiation 6
Synonyms: Math-2, Nex, Atoh2, Nex1m, Math2, bHLHa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11922
Homologene: 7632
Sptb
Name: spectrin beta, erythrocytic
Synonyms: Spnb-1, spectrin R, D330027P03Rik, LOC383567, brain erythroid spectrin (235E), Spnb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20741
Homologene: 295
Ppp3ca
Name: protein phosphatase 3, catalytic subunit, alpha isoform
Synonyms: CnA, PP2B alpha 1, PP2BA alpha, Caln, Calna, 2900074D19Rik, CN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19055
HGNC: HGNC:9314
Homologene: 55497
Hnrnph3
Name: heterogeneous nuclear ribonucleoprotein H3
Synonyms: hnRNP 2H9, Hnrph3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 432467
HGNC: HGNC:5043
Homologene: 11012
Siglecf
Name: sialic acid binding Ig-like lectin F
Synonyms: mSiglec-F, Siglec5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233186
Homologene: 50482
Myo15
Name: myosin XV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17910
HGNC: HGNC:7594
Homologene: 56504
Efcab2
Name: EF-hand calcium binding domain 2
Synonyms: D830011E08Rik, 1700073K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68226
Homologene: 12248
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh-4, C130041O22Rik, Zfh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80892
Homologene: 23477
Mocos
Name: molybdenum cofactor sulfurase
Synonyms: 1110018O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68591
VEGA: 18
Homologene: 9931
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Ms4a10
Name: membrane-spanning 4-domains, subfamily A, member 10
Synonyms: 2010001N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 69826
Homologene: 11355
Trappc11
Name: trafficking protein particle complex 11
Synonyms: D030016E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 320714
Homologene: 11076
Add2
Name: adducin 2 (beta)
Synonyms: 2900072M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11519
HGNC: HGNC:244
Homologene: 1221
Gen1
Name: GEN1, Holliday junction 5' flap endonuclease
Synonyms: 5830483C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 209334
VEGA: 12
Homologene: 35313
Rb1cc1
Name: RB1-inducible coiled-coil 1
Synonyms: LaXp180, 2900055E04Rik, Cc1, 5930404L04Rik, Fip200
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12421
Homologene: 7659
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Trmt11
Name: tRNA methyltransferase 11
Synonyms: 3110045I18Rik, 2410075D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 73681
VEGA: 10
Homologene: 6876
Ak9
Name: adenylate kinase 9
Synonyms: LOC215946, Akd2, Gm7127, Akd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 633979
Homologene: 67934
Btn2a2
Name: butyrophilin, subfamily 2, member A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238555
HGNC: HGNC:1137
Homologene: 56012
Olfr618
Name: olfactory receptor 618
Synonyms: GA_x6K02T2PBJ9-6320148-6321104, MOR31-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259049
Homologene: 72966
Fbrs
Name: fibrosin
Synonyms: Fbs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14123
Homologene: 79554
Map3k19
Name: mitogen-activated protein kinase kinase kinase 19
Synonyms: Ysk4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22625
Homologene: 19318
Tas2r137
Name: taste receptor, type 2, member 137
Synonyms: mt2r41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 574417
Homologene: 23231
Olfr1448
Name: olfactory receptor 1448
Synonyms: GA_x6K02T2RE5P-3249780-3248836, MOR202-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258696
Homologene: 64904
Rab34
Name: RAB34, member RAS oncogene family
Synonyms: Rah1, Narr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19376
Homologene: 12908
Olfr56
Name: olfactory receptor 56
Synonyms: IF7, MOR276-1, GA_x6K02T2QP88-6300500-6299553
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18356
HGNC: HGNC:8280
Homologene: 22608
Cyp4a12b
Name: cytochrome P450, family 4, subfamily a, polypeptide 12B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13118
Homologene: 134044
Pcdhb17
Name: protocadherin beta 17
Synonyms: Pcdhb16, PcdhbQ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93888
Homologene: 81881
Spire1
Name: spire type actin nucleation factor 1
Synonyms: Spir-1, 6030430B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68166
VEGA: 18
Homologene: 35507
Zhx3
Name: zinc fingers and homeoboxes 3
Synonyms: 4932418O04Rik, 1810059C13Rik, 9530010N21Rik, Tix1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320799
Homologene: 9000
Epn1
Name: epsin 1
Synonyms: Ibp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13854
Homologene: 32172
Gm1818
Name: predicted gene 1818
Synonyms: LOC217536
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217536
VEGA: 12
Slc25a2
Name: solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2
Synonyms: Ornt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 83885
Homologene: 129775
Glrx2
Name: glutaredoxin 2 (thioltransferase)
Synonyms: 1700010P22Rik, Grx2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 69367
Homologene: 41098
Ighv12-3
Name: immunoglobulin heavy variable V12-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 435321
Apitd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Trbv11
Name: T cell receptor beta variable 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100124671
Tspo
Name: translocator protein
Synonyms: PBR, Bzrp, Tspo1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12257
HGNC: HGNC:1158
Homologene: 574
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 6,248,182 bp
  • G to A, chromosome 1 at 39,999,922 bp
  • T to C, chromosome 1 at 127,822,740 bp
  • A to G, chromosome 1 at 143,745,134 bp
  • A to G, chromosome 1 at 178,475,874 bp
  • A to G, chromosome 1 at 190,885,420 bp
  • A to G, chromosome 1 at 193,332,362 bp
  • T to C, chromosome 2 at 76,880,225 bp
  • T to A, chromosome 2 at 156,503,788 bp
  • G to T, chromosome 2 at 156,524,983 bp
  • A to T, chromosome 2 at 160,782,017 bp
  • A to G, chromosome 3 at 5,396,970 bp
  • A to G, chromosome 3 at 36,965,621 bp
  • A to T, chromosome 3 at 136,928,571 bp
  • C to T, chromosome 4 at 115,414,517 bp
  • C to A, chromosome 4 at 149,130,201 bp
  • A to G, chromosome 6 at 23,247,428 bp
  • T to C, chromosome 6 at 40,491,542 bp
  • A to G, chromosome 6 at 41,107,219 bp
  • G to A, chromosome 6 at 55,679,017 bp
  • A to T, chromosome 6 at 86,109,746 bp
  • G to A, chromosome 7 at 5,093,912 bp
  • C to T, chromosome 7 at 43,355,927 bp
  • T to C, chromosome 7 at 99,925,633 bp
  • T to A, chromosome 7 at 103,597,967 bp
  • T to C, chromosome 7 at 127,487,752 bp
  • G to T, chromosome 8 at 25,181,995 bp
  • A to T, chromosome 8 at 47,496,917 bp
  • A to T, chromosome 10 at 28,585,675 bp
  • A to G, chromosome 10 at 30,560,842 bp
  • A to G, chromosome 10 at 41,357,563 bp
  • A to G, chromosome 10 at 63,015,595 bp
  • A to T, chromosome 10 at 69,986,463 bp
  • A to T, chromosome 11 at 49,134,572 bp
  • A to G, chromosome 11 at 60,479,420 bp
  • G to T, chromosome 11 at 78,190,268 bp
  • A to T, chromosome 12 at 11,260,896 bp
  • T to G, chromosome 12 at 48,555,936 bp
  • A to G, chromosome 12 at 71,063,206 bp
  • A to T, chromosome 12 at 76,632,384 bp
  • A to T, chromosome 12 at 114,366,584 bp
  • A to T, chromosome 13 at 23,482,808 bp
  • A to G, chromosome 15 at 47,733,505 bp
  • A to G, chromosome 15 at 77,773,332 bp
  • A to G, chromosome 15 at 83,572,240 bp
  • A to T, chromosome 15 at 98,658,240 bp
  • C to A, chromosome 16 at 18,935,065 bp
  • A to G, chromosome 18 at 4,674,554 bp
  • T to C, chromosome 18 at 24,701,387 bp
  • T to C, chromosome 18 at 37,487,080 bp
  • T to C, chromosome 18 at 37,638,282 bp
  • A to G, chromosome 18 at 67,506,709 bp
  • T to A, chromosome 19 at 10,964,122 bp
  • T to C, chromosome 19 at 12,919,830 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5952 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044142-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.