Strain Name:
C57BL/6J-MtgxR5977Btlr
Stock Number:
044159-MU
Citation ID:
RRID:MMRRC_044159-MU
Other Names:
R5977 (G1)
Major Collection:

Gene Information

Sbf2
Name: SET binding factor 2
Synonyms: 4833411B01Rik, Mtmr13, B430219L04Rik, SBF2, mMTMH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319934
HGNC: HGNC:2135
Homologene: 41810
Gcm2
Name: glial cells missing homolog 2
Synonyms: Gcm1-rs2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 107889
VEGA: 13
HGNC: HGNC:4198
Homologene: 3490
Cr1l
Name: complement component (3b/4b) receptor 1-like
Synonyms: Crry, mCRY
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12946
HGNC: HGNC:2335
Homologene: 128275
Cbfa2t2
Name: CBFA2/RUNX1 translocation partner 2
Synonyms: C330013D05Rik, Cbfa2t2h, MTGR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12396
HGNC: HGNC:1536
Homologene: 3733
Cemip2
Name: cell migration inducing hyaluronidase 2
Synonyms: 3110012M15Rik, Tmem2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 83921
VEGA: 19
Homologene: 75008
Nup155
Name: nucleoporin 155
Synonyms: D930027M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 170762
VEGA: 15
HGNC: HGNC:8063
Homologene: 43155
Arl15
Name: ADP-ribosylation factor-like 15
Synonyms: Arfrp2, C230032K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218639
Homologene: 56843
Dscaml1
Name: DS cell adhesion molecule like 1
Synonyms: 4930435C18Rik, 4921507G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 114873
VEGA: 9
Homologene: 79549
Carmil1
Name: capping protein regulator and myosin 1 linker 1
Synonyms: Lrrc16, 1110037D04Rik, Lrrc16a, Carmil
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 68732
Homologene: 9757
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, A430032G04Rik, A430040A19Rik, D630005A10Rik, Bruce
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Mtdh
Name: metadherin
Synonyms: 3D3/Lyric, 2610103J23Rik, D8Bwg1112e, Lyric, AEG-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67154
Homologene: 12089
Smg1
Name: SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
Synonyms: C130002K18Rik, 5430435M13Rik, 2610207I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233789
Homologene: 56697
Dmtf1
Name: cyclin D binding myb-like transcription factor 1
Synonyms: Dmp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 23857
Homologene: 8017
Dhrs7b
Name: dehydrogenase/reductase (SDR family) member 7B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216820
Homologene: 41044
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: tbl, 2810449H11Rik, D130015N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Uvssa
Name: UV stimulated scaffold protein A
Synonyms: D330017J19Rik, 4933407H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71101
Homologene: 13807
Hey1
Name: hairy/enhancer-of-split related with YRPW motif 1
Synonyms: Hesr1, Herp2, hesr-1, bHLHb31, HRT1, CHF2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 15213
HGNC: HGNC:4880
Homologene: 7756
Unc119b
Name: unc-119 lipid binding chaperone B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 106840
Homologene: 43997
Scube1
Name: signal peptide, CUB domain, EGF-like 1
Synonyms: A630023E24Rik, 7330410C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 64706
Homologene: 11224
Il17rc
Name: interleukin 17 receptor C
Synonyms: IL17-RL, Il17rl, 1110025H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171095
Homologene: 15894
Papln
Name: papilin, proteoglycan-like sulfated glycoprotein
Synonyms: E030033C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 170721
Homologene: 71541
Zcchc7
Name: zinc finger, CCHC domain containing 7
Synonyms: 4930572I07Rik, D4Wsu132e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 319885
Homologene: 22217
Marveld2
Name: MARVEL (membrane-associating) domain containing 2
Synonyms: Tric-b, Mrvldc2, Tric, Tricellulin, Tric-c, Tric-a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218518
VEGA: 13
Homologene: 27037
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Efhc1
Name: EF-hand domain (C-terminal) containing 1
Synonyms: 1700029F22Rik, mRib72-1, myoclonin1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71877
Homologene: 10003
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, Dnahc2, Dnhd3, 2900022L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Myh15
Name: myosin, heavy chain 15
Synonyms: EG667772
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 667772
VEGA: 16
Homologene: 18929
2900092C05Rik
Name: RIKEN cDNA 2900092C05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73090
Homologene: 49900
Rab19
Name: RAB19, member RAS oncogene family
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19331
Homologene: 22623
Ankrd52
Name: ankyrin repeat domain 52
Synonyms: G431002C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237615
Homologene: 18227
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: Mgr1, Gpr98, Mass1, VLGR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110789
Homologene: 19815
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Relt
Name: RELT tumor necrosis factor receptor
Synonyms: Tnfrsf19l, E430021K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 320100
Homologene: 13151
Vmn1r69
Name: vomeronasal 1 receptor 69
Synonyms: V1re9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 252904
Homologene: 120153
Vmn2r78
Name: vomeronasal 2, receptor 78
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 637896
Homologene: 115466
Egflam
Name: EGF-like, fibronectin type III and laminin G domains
Synonyms: nectican, pikachurin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 268780
Homologene: 65044
Cped1
Name: cadherin-like and PC-esterase domain containing 1
Synonyms: A430107O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 214642
Homologene: 57014
A2ml1
Name: alpha-2-macroglobulin like 1
Synonyms: Ovos2, BC048546
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232400
Homologene: 45969
Ddx60
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234311
Homologene: 23031
1700017N19Rik
Name: RIKEN cDNA 1700017N19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66605
Homologene: 45135
Csmd2
Name: CUB and Sushi multiple domains 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329942
Homologene: 89034
Prss39
Name: protease, serine 39
Synonyms: Tesp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21755
Homologene: 84781
Nek8
Name: NIMA (never in mitosis gene a)-related expressed kinase 8
Synonyms: b2b1449Clo, 4632401F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 140859
Homologene: 84442
Olfr1390
Name: olfactory receptor 1390
Synonyms: GA_x6K02T2QP88-6094111-6093176, MOR256-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259068
Ugt1a6b
Name: UDP glucuronosyltransferase 1 family, polypeptide A6B
Synonyms: A9'
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 394435
Homologene: 85959
Vmn2r7
Name: vomeronasal 2, receptor 7
Synonyms: 4933425M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 319217
Homologene: 129754
Shisa9
Name: shisa family member 9
Synonyms: CKAMP44, 2700045P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 72555
Homologene: 109462
Atp8a1
Name: ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
Synonyms: Atp3a2, B230107D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11980
Homologene: 48402
Vmn2r54
Name: vomeronasal 2, receptor 54
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 666085
Homologene: 104040
Sncaip
Name: synuclein, alpha interacting protein (synphilin)
Synonyms: 4933427B05Rik, SYPH1, synphilin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67847
Homologene: 3987
Sec14l4
Name: SEC14-like lipid binding 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103655
Homologene: 68807
Pyroxd2
Name: pyridine nucleotide-disulphide oxidoreductase domain 2
Synonyms: 3830409H07Rik, 4833409A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74580
VEGA: 19
Homologene: 13097
Pcdhb17
Name: protocadherin beta 17
Synonyms: Pcdhb16, PcdhbQ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93888
Homologene: 81881
Sorcs3
Name: sortilin-related VPS10 domain containing receptor 3
Synonyms: 6330404A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66673
VEGA: 19
Homologene: 8986
Cryl1
Name: crystallin, lambda 1
Synonyms: 1110025H08Rik, A230106J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68631
VEGA: 14
Homologene: 9322
Gpr182
Name: G protein-coupled receptor 182
Synonyms: AM-R, Gpcr22, Gpcr17, Admr, NOW, G10-D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11536
Homologene: 5255
Vmn1r199
Name: vomeronasal 1 receptor 199
Synonyms: V1rh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171247
Homologene: 110880
Kbtbd4
Name: kelch repeat and BTB (POZ) domain containing 4
Synonyms: 2510026C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67136
Homologene: 32320
Wdr5b
Name: WD repeat domain 5B
Synonyms: 2310009C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 69544
VEGA: 16
Homologene: 41307
Anks6
Name: ankyrin repeat and sterile alpha motif domain containing 6
Synonyms: 2210417J20Rik, Samd6, LOC269533, SamCystin, b2b1801.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75691
Homologene: 19545
Pramef8
Name: PRAME family member 8
Synonyms: 4732496O08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242736
Homologene: 128393
Olfr883
Name: olfactory receptor 883
Synonyms: GA_x6K02T2PVTD-31705144-31706073, MOR162-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258414
Homologene: 86689
Gm3443
Name: predicted gene 3443
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Olfr1356
Name: olfactory receptor 1356
Synonyms: MOR142-1, GA_x6K02T2QGN0-2962025-2962987, MOR142-2_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258305
HGNC: HGNC:8374
Homologene: 71958
Ighv1-43
Name: immunoglobulin heavy variable V1-43
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 629908
Zfp729b
Name: zinc finger protein 729b
Synonyms: AA987161
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 100416706
Homologene: 133713
4933405O20Rik
Name: RIKEN cDNA 4933405O20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243996
Gm18358
Name: predicted gene, 18358
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100417008
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 20,960,218 bp
  • T to G, chromosome 1 at 34,502,702 bp
  • C to T, chromosome 1 at 88,216,260 bp
  • A to G, chromosome 1 at 90,821,849 bp
  • A to T, chromosome 1 at 195,114,768 bp
  • T to G, chromosome 2 at 90,906,143 bp
  • T to C, chromosome 2 at 154,517,777 bp
  • A to T, chromosome 3 at 8,666,358 bp
  • C to T, chromosome 3 at 64,716,043 bp
  • G to A, chromosome 4 at 44,894,982 bp
  • C to A, chromosome 4 at 47,035,748 bp
  • C to T, chromosome 4 at 128,059,034 bp
  • T to C, chromosome 4 at 143,417,659 bp
  • T to C, chromosome 5 at 9,140,451 bp
  • A to G, chromosome 5 at 33,389,860 bp
  • A to G, chromosome 5 at 67,747,285 bp
  • A to G, chromosome 5 at 115,130,553 bp
  • T to C, chromosome 6 at 22,254,608 bp
  • T to A, chromosome 6 at 39,383,926 bp
  • T to C, chromosome 6 at 113,482,731 bp
  • A to G, chromosome 6 at 128,581,122 bp
  • G to A, chromosome 7 at 10,580,490 bp
  • A to T, chromosome 7 at 12,554,737 bp
  • A to G, chromosome 7 at 12,632,216 bp
  • G to A, chromosome 7 at 50,600,090 bp
  • A to G, chromosome 7 at 85,090,548 bp
  • T to A, chromosome 7 at 86,920,333 bp
  • T to A, chromosome 7 at 86,954,907 bp
  • A to G, chromosome 7 at 100,863,148 bp
  • T to A, chromosome 7 at 110,377,986 bp
  • A to G, chromosome 7 at 118,141,357 bp
  • T to C, chromosome 7 at 141,796,367 bp
  • G to A, chromosome 8 at 62,021,410 bp
  • ATTGCTGTTT to ATTGCTGTTTGCTGTTT, chromosome 9 at 38,026,540 bp
  • A to C, chromosome 9 at 45,721,298 bp
  • T to A, chromosome 9 at 66,433,322 bp
  • A to T, chromosome 10 at 78,847,738 bp
  • A to T, chromosome 10 at 100,615,244 bp
  • C to A, chromosome 10 at 127,750,879 bp
  • C to T, chromosome 10 at 128,382,697 bp
  • A to C, chromosome 11 at 4,040,055 bp
  • G to A, chromosome 11 at 49,340,765 bp
  • C to T, chromosome 11 at 60,852,502 bp
  • T to C, chromosome 11 at 69,520,881 bp
  • C to T, chromosome 11 at 78,167,825 bp
  • G to A, chromosome 12 at 83,784,369 bp
  • A to C, chromosome 12 at 114,946,209 bp
  • A to C, chromosome 13 at 22,383,246 bp
  • C to T, chromosome 13 at 24,069,736 bp
  • A to G, chromosome 13 at 41,103,127 bp
  • G to A, chromosome 13 at 67,591,621 bp
  • C to T, chromosome 13 at 81,435,559 bp
  • T to C, chromosome 13 at 100,611,689 bp
  • T to G, chromosome 13 at 113,934,109 bp
  • G to T, chromosome 14 at 57,382,779 bp
  • T to A, chromosome 15 at 7,318,245 bp
  • T to A, chromosome 15 at 8,130,237 bp
  • A to G, chromosome 15 at 34,099,574 bp
  • C to T, chromosome 15 at 83,629,488 bp
  • C to G, chromosome 16 at 12,267,428 bp
  • T to G, chromosome 16 at 36,042,004 bp
  • T to C, chromosome 16 at 49,153,503 bp
  • T to C, chromosome 17 at 74,603,036 bp
  • A to G, chromosome 18 at 37,485,667 bp
  • A to G, chromosome 18 at 52,869,321 bp
  • T to G, chromosome 19 at 21,557,596 bp
  • A to G, chromosome 19 at 21,826,083 bp
  • A to G, chromosome 19 at 42,735,472 bp
  • T to C, chromosome 19 at 48,796,450 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5977 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044159-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.