Strain Name:
C57BL/6J-MtgxR5995Btlr
Stock Number:
044174-MU
Citation ID:
RRID:MMRRC_044174-MU
Other Names:
R5995 (G1)
Major Collection:

Gene Information

Nfkbil1
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
Synonyms: Def-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18038
HGNC: HGNC:7800
Homologene: 3671
Myh10
Name: myosin, heavy polypeptide 10, non-muscle
Synonyms: 9330167F11Rik, NMHC-B, 5730504C04Rik, SMemb, nonmuscle myosin heavy chain IIB, Myhn2, Myosin IIB, Fltn, Fltn, Myhn-2, nonmuscle myosin heavy chain II-B, myosin IIB, NMHC II-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77579
HGNC: HGNC:7568
Homologene: 55941
Supt20
Name: SPT20 SAGA complex component
Synonyms: p38IP, Fam48a, p38 interacting protein, D3Ertd300e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56790
Homologene: 134155
Brwd1
Name: bromodomain and WD repeat domain containing 1
Synonyms: repro5, Wdr9, D530019K20Rik, 5330419I02Rik, G1-403-16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 93871
Homologene: 23130
Cyp7a1
Name: cytochrome P450, family 7, subfamily a, polypeptide 1
Synonyms: cholesterol 7 alpha hydroxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13122
HGNC: HGNC:2651
Homologene: 30987
Oprm1
Name: opioid receptor, mu 1
Synonyms: MOP receptor, mor, MOR-1, Oprm, muOR, MOP-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18390
HGNC: HGNC:8156
Homologene: 37368
Abcb8
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 8
Synonyms: 4833412N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74610
HGNC: HGNC:49
Homologene: 5203
Pex1
Name: peroxisomal biogenesis factor 1
Synonyms: E330005K07Rik, peroxisome biogenesis factor 1, 5430414H02Rik, ZWS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71382
HGNC: HGNC:8850
Homologene: 27006
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, LOC381341, Dnahc7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 627872
Homologene: 41287
Adgrb2
Name: adhesion G protein-coupled receptor B2
Synonyms: Bai2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230775
HGNC: HGNC:944
Homologene: 1288
Zfp980
Name: zinc finger protein 980
Synonyms: Gm13242
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100041379
Homologene: 133076
Hoxa3
Name: homeobox A3
Synonyms: Hox-1.5, Mo-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 15400
HGNC: HGNC:5104
Homologene: 40725
Crtam
Name: cytotoxic and regulatory T cell molecule
Synonyms: class I-restricted T cell-associated molecule
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 54698
Homologene: 10454
Ythdc2
Name: YTH domain containing 2
Synonyms: 3010002F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240255
Homologene: 11265
Cdv3
Name: carnitine deficiency-associated gene expressed in ventricle 3
Synonyms: TPP36, 2510010F10Rik, C230084J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 321022
Homologene: 133862
H2-T22
Name: histocompatibility 2, T region locus 22
Synonyms: H-2T22, H-2T17, H2-T17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15039
Homologene: 79525
Ttn
Name: titin
Synonyms: mdm, 2310036G12Rik, D830007G01Rik, shru, L56, 2310074I15Rik, 2310057K23Rik, connectin, D330041I19Rik, 1100001C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Colgalt1
Name: collagen beta(1-O)galactosyltransferase 1
Synonyms: Glt25d1, 2810024B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234407
Homologene: 23465
Nlrp1b
Name: NLR family, pyrin domain containing 1B
Synonyms: Nalp1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 637515
Homologene: 19080
Snrk
Name: SNF related kinase
Synonyms: SNRK, 2010012F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20623
Homologene: 9797
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: Mgr1, Gpr98, Mass1, VLGR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110789
Homologene: 19815
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242627
Homologene: 135888
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22635
Homologene: 124417
Cd109
Name: CD109 antigen
Synonyms: Gov platelet alloantigens, 9930012E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235505
Homologene: 25183
Ces2c
Name: carboxylesterase 2C
Synonyms: Ces2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234671
HGNC: HGNC:1864
Homologene: 138298
Gm7247
Name: predicted gene 7247
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 638695
Gria1
Name: glutamate receptor, ionotropic, AMPA1 (alpha 1)
Synonyms: 2900051M01Rik, GluA1, Glur1, Glr1, HIPA1, GluR-A, Glr-1, GluR1, GluRA, Glur-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14799
HGNC: HGNC:4571
Homologene: 20226
Nod1
Name: nucleotide-binding oligomerization domain containing 1
Synonyms: F830007N14Rik, Nlrc1, Card4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 107607
Homologene: 4440
Zfp521
Name: zinc finger protein 521
Synonyms: Evi3, B930086A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225207
VEGA: 18
Homologene: 9151
Slc2a7
Name: solute carrier family 2 (facilitated glucose transporter), member 7
Synonyms: OTTMUSG00000010396
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 435818
Homologene: 72470
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: ojoplano, Opo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218165
VEGA: 13
Homologene: 125376
Vmn2r92
Name: vomeronasal 2, receptor 92
Synonyms: EG627111
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627111
Homologene: 115024
Olfr1446
Name: olfactory receptor 1446
Synonyms: GA_x6K02T2RE5P-3220047-3219130, MOR202-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258699
Homologene: 74233
Ccdc96
Name: coiled-coil domain containing 96
Synonyms: 4921513E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66717
Homologene: 32639
Onecut2
Name: one cut domain, family member 2
Synonyms: Oc2, OC-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225631
HGNC: HGNC:8139
Homologene: 113592
Vmn2r11
Name: vomeronasal 2, receptor 11
Synonyms: EG384219
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 384219
Homologene: 129606
Hif3a
Name: hypoxia inducible factor 3, alpha subunit
Synonyms: bHLHe17, Nepas, MOP7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 53417
Homologene: 9646
Olfr1419
Name: olfactory receptor 1419
Synonyms: GA_x6K02T2RE5P-2222521-2221490, MOR266-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 257938
Homologene: 79473
Klhl33
Name: kelch-like 33
Synonyms: EG546611
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 546611
VEGA: 14
Homologene: 52385
Rbm20
Name: RNA binding motif protein 20
Synonyms: 2010003H22Rik, 1110018J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 73713
Homologene: 28386
Olfr385
Name: olfactory receptor 385
Synonyms: MOR135-3, GA_x6K02T2P1NL-3760313-3759375
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259025
Homologene: 133670
Pou2f2
Name: POU domain, class 2, transcription factor 2
Synonyms: Oct-2, Oct2c, Oct2d, Otf-2, Otf2, Oct2b, Oct2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18987
HGNC: HGNC:9213
Homologene: 55674
Gm12185
Name: predicted gene 12185
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 620913
Homologene: 83188
Bend6
Name: BEN domain containing 6
Synonyms: B230209C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320705
Homologene: 27394
Klhdc1
Name: kelch domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 271005
Homologene: 18155
Cd44
Name: CD44 antigen
Synonyms: HERMES, Pgp-1, Ly-24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12505
HGNC: HGNC:1681
Homologene: 508
Olfr98
Name: olfactory receptor 98
Synonyms: GA_x6K02T2PSCP-1703582-1702653, MOR156-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258503
Homologene: 133051
Hace1
Name: HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
Synonyms: 1700042J16Rik, A730034A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 209462
Homologene: 10807
Olfr1110
Name: olfactory receptor 1110
Synonyms: GA_x6K02T2Q125-48621299-48620361, MOR172-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258765
Sh3tc2
Name: SH3 domain and tetratricopeptide repeats 2
Synonyms: D430044G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225608
VEGA: 18
Homologene: 11596
Poglut3
Name: protein O-glucosyltransferase 3
Synonyms: 4833410J10Rik, Kdelc2, 2010004J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68304
VEGA: 9
Homologene: 17805
Dok6
Name: docking protein 6
Synonyms: Dok-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 623279
Homologene: 45143
Il27
Name: interleukin 27
Synonyms: IL-27, p28, IL-27p28, Il30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 246779
Homologene: 17087
Olfr968
Name: olfactory receptor 968
Synonyms: GA_x6K02T2PVTD-33470347-33469403, MOR171-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258605
VEGA: 9
Homologene: 121532
Pcdhgc5
Name: protocadherin gamma subfamily C, 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93708
HGNC: HGNC:8718
Homologene: 110933
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 33,878,439 bp
  • A to T, chromosome 1 at 53,620,670 bp
  • A to G, chromosome 2 at 76,761,292 bp
  • T to C, chromosome 2 at 87,135,856 bp
  • A to G, chromosome 2 at 102,861,670 bp
  • T to C, chromosome 3 at 54,709,053 bp
  • C to T, chromosome 4 at 6,272,371 bp
  • T to A, chromosome 4 at 113,893,832 bp
  • C to A, chromosome 4 at 130,017,103 bp
  • A to T, chromosome 4 at 145,701,909 bp
  • T to C, chromosome 4 at 150,168,340 bp
  • T to A, chromosome 5 at 3,607,704 bp
  • C to T, chromosome 5 at 24,400,139 bp
  • A to G, chromosome 5 at 36,486,374 bp
  • T to A, chromosome 5 at 109,047,055 bp
  • T to C, chromosome 5 at 137,378,809 bp
  • T to A, chromosome 6 at 52,170,283 bp
  • A to G, chromosome 6 at 54,944,554 bp
  • T to A, chromosome 7 at 17,053,769 bp
  • T to G, chromosome 7 at 25,097,444 bp
  • A to C, chromosome 7 at 126,589,363 bp
  • T to A, chromosome 8 at 71,623,110 bp
  • T to A, chromosome 8 at 104,850,901 bp
  • A to G, chromosome 9 at 39,772,692 bp
  • G to A, chromosome 9 at 40,994,540 bp
  • T to C, chromosome 9 at 53,395,895 bp
  • A to T, chromosome 9 at 78,700,279 bp
  • C to G, chromosome 9 at 103,364,003 bp
  • A to G, chromosome 9 at 122,157,222 bp
  • A to C, chromosome 10 at 6,832,520 bp
  • A to T, chromosome 10 at 45,670,391 bp
  • T to C, chromosome 11 at 48,915,713 bp
  • A to T, chromosome 11 at 57,289,285 bp
  • T to C, chromosome 11 at 68,814,983 bp
  • A to T, chromosome 11 at 71,181,746 bp
  • T to C, chromosome 11 at 73,589,250 bp
  • T to C, chromosome 12 at 69,250,774 bp
  • A to G, chromosome 13 at 40,280,422 bp
  • A to G, chromosome 13 at 81,466,259 bp
  • T to G, chromosome 14 at 50,892,651 bp
  • C to T, chromosome 14 at 51,364,348 bp
  • A to T, chromosome 15 at 76,185,905 bp
  • A to T, chromosome 16 at 96,064,787 bp
  • T to C, chromosome 17 at 18,168,951 bp
  • G to T, chromosome 17 at 35,220,798 bp
  • A to G, chromosome 17 at 36,041,485 bp
  • C to A, chromosome 17 at 37,263,648 bp
  • C to A, chromosome 18 at 13,717,624 bp
  • T to A, chromosome 18 at 37,821,060 bp
  • T to A, chromosome 18 at 44,886,253 bp
  • T to A, chromosome 18 at 61,990,010 bp
  • G to T, chromosome 18 at 64,341,548 bp
  • T to C, chromosome 18 at 89,421,018 bp
  • A to T, chromosome 19 at 11,870,862 bp
  • A to C, chromosome 19 at 12,890,597 bp
  • G to A, chromosome 19 at 53,851,267 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5995 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044174-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.