Strain Name:
C57BL/6J-MtgxR5998Btlr
Stock Number:
044177-MU
Citation ID:
RRID:MMRRC_044177-MU
Other Names:
R5998 (G1)
Major Collection:

Gene Information

Adcy10
Name: adenylate cyclase 10
Synonyms: sAC, soluble adenylyl cyclase, 4930431D04Rik, Sacy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 271639
Homologene: 10188
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNAPDcs, dxnph, slip, XRCC7, DNA-PKcs, DNA-PK, DOXNPH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Tmem63b
Name: transmembrane protein 63b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224807
Homologene: 101682
Kcnq2
Name: potassium voltage-gated channel, subfamily Q, member 2
Synonyms: Nmf134, KQT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16536
HGNC: HGNC:6296
Homologene: 26174
Mtcl1
Name: microtubule crosslinking factor 1
Synonyms: Soga2, t8219b25, 1110012J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 68617
Homologene: 41017
Helz
Name: helicase with zinc finger domain
Synonyms: 9430093I07Rik, 3110078M01Rik, 9630002H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 78455
Homologene: 8918
Zfp516
Name: zinc finger protein 516
Synonyms: Zfp26l, C330029B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 329003
VEGA: 18
Homologene: 37122
Mcm3ap
Name: minichromosome maintenance complex component 3 associated protein
Synonyms: GANP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 54387
VEGA: 10
HGNC: HGNC:6946
Homologene: 2902
Glb1l2
Name: galactosidase, beta 1-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244757
Homologene: 71790
Pigt
Name: phosphatidylinositol glycan anchor biosynthesis, class T
Synonyms: NDAP, Ndap7, 4930534E15Rik, CGI-06, 2510012P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 78928
Homologene: 6134
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Pkdrej
Name: polycystin (PKD) family receptor for egg jelly
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18766
VEGA: 15
HGNC: HGNC:9015
Homologene: 4427
Adgrb3
Name: adhesion G protein-coupled receptor B3
Synonyms: Bai3, A830096D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210933
HGNC: HGNC:945
Homologene: 1289
Ahrr
Name: aryl-hydrocarbon receptor repressor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11624
HGNC: HGNC:346
Homologene: 49215
Ankrd52
Name: ankyrin repeat domain 52
Synonyms: G431002C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237615
Homologene: 18227
Adcy3
Name: adenylate cyclase 3
Synonyms: ACIII, AC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104111
HGNC: HGNC:234
Homologene: 2978
Acot12
Name: acyl-CoA thioesterase 12
Synonyms: 1300004O04Rik, Cach, 4930449F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 74156
Homologene: 12540
Eif4a3l1
Name: eukaryotic translation initiation factor 4A3 like 1
Synonyms: B020013A22Rik, Gm8994
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 668137
Adcy6
Name: adenylate cyclase 6
Synonyms: AC6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11512
VEGA: 15
HGNC: HGNC:237
Homologene: 22400
Ppp1r32
Name: protein phosphatase 1, regulatory subunit 32
Synonyms: IIIG9, IIIG9S, IIIG9L, 4930579J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67752
VEGA: 19
Homologene: 15863
Atp8b4
Name: ATPase, class I, type 8B, member 4
Synonyms: Im
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241633
Homologene: 133162
Olfr926
Name: olfactory receptor 926
Synonyms: GA_x6K02T2PVTD-32573036-32573962, MOR171-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258811
VEGA: 9
HGNC: HGNC:8482
Homologene: 128215
Zfp780b
Name: zinc finger protein 780B
Synonyms: B230208L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 338354
Homologene: 85969
Cyp2a5
Name: cytochrome P450, family 2, subfamily a, polypeptide 5
Synonyms: Coh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13087
Homologene: 85917
Gm10471
Name: predicted gene 10471
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100039045
Homologene: 69402
Olfr180
Name: olfactory receptor 180
Synonyms: Olfr1563-ps1, MOR184-9, MOR184-11P, GA_x54KRFPKG5P-55134972-55134019, MOR184-11P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258178
Homologene: 79337
Micall2
Name: MICAL-like 2
Synonyms: Jrab, A930021H16Rik, MICAL-L2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231830
Homologene: 85155
Mill2
Name: MHC I like leukocyte 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243864
HGNC: HGNC:7091
Homologene: 88329
Btbd19
Name: BTB (POZ) domain containing 19
Synonyms: 9530048O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 78611
Igkv15-103
Name: immunoglobulin kappa chain variable 15-103
Synonyms: Igk-V32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 692169
Bcl6b
Name: B cell CLL/lymphoma 6, member B
Synonyms: Bazf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12029
HGNC: HGNC:1002
Homologene: 7243
Hmha1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 25,431,501 bp
  • A to G, chromosome 1 at 165,541,649 bp
  • A to G, chromosome 2 at 126,433,867 bp
  • A to G, chromosome 2 at 164,507,454 bp
  • T to C, chromosome 2 at 181,087,008 bp
  • T to A, chromosome 4 at 117,120,999 bp
  • T to C, chromosome 5 at 26,084,706 bp
  • T to C, chromosome 5 at 139,706,911 bp
  • T to A, chromosome 6 at 68,437,505 bp
  • T to C, chromosome 6 at 136,328,624 bp
  • A to G, chromosome 7 at 18,840,064 bp
  • G to A, chromosome 7 at 26,837,153 bp
  • T to A, chromosome 7 at 27,964,622 bp
  • G to A, chromosome 8 at 15,910,443 bp
  • G to A, chromosome 9 at 26,766,003 bp
  • G to A, chromosome 9 at 38,877,869 bp
  • T to C, chromosome 10 at 76,481,142 bp
  • T to C, chromosome 10 at 80,030,950 bp
  • T to C, chromosome 10 at 128,383,123 bp
  • G to A, chromosome 11 at 9,567,708 bp
  • A to C, chromosome 11 at 70,228,183 bp
  • G to T, chromosome 11 at 107,685,534 bp
  • T to A, chromosome 12 at 4,198,348 bp
  • T to A, chromosome 13 at 74,213,836 bp
  • T to C, chromosome 13 at 91,757,534 bp
  • A to G, chromosome 15 at 85,815,453 bp
  • C to A, chromosome 15 at 98,594,354 bp
  • T to A, chromosome 16 at 15,783,157 bp
  • T to C, chromosome 16 at 58,916,630 bp
  • A to G, chromosome 17 at 45,670,000 bp
  • G to A, chromosome 17 at 66,368,280 bp
  • T to C, chromosome 18 at 82,956,514 bp
  • A to T, chromosome 19 at 10,481,352 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5998 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044177-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.