Strain Name:
C57BL/6J-MtgxR5999Btlr
Stock Number:
044178-MU
Citation ID:
RRID:MMRRC_044178-MU
Other Names:
R5999 (G1)
Major Collection:

Gene Information

Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: E330008K23Rik, HALR, Mll3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231051
Homologene: 46480
Ccdc88c
Name: coiled-coil domain containing 88C
Synonyms: Daple, 0610010D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68339
VEGA: 12
Homologene: 18903
Nr5a2
Name: nuclear receptor subfamily 5, group A, member 2
Synonyms: D1Ertd308e, UF2-H3B, LRH-1, Ftf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 26424
HGNC: HGNC:7984
Homologene: 20827
Elp3
Name: elongator acetyltransferase complex subunit 3
Synonyms: 2610507P14Rik, KAT9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 74195
VEGA: 14
Homologene: 7105
Inpp5k
Name: inositol polyphosphate 5-phosphatase K
Synonyms: putative PI-5-phosphatase, PI-5-phosphatase related, Pps, C62
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19062
Homologene: 75059
Cltc
Name: clathrin, heavy polypeptide (Hc)
Synonyms: CHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67300
HGNC: HGNC:2092
Homologene: 3572
Prep
Name: prolyl endopeptidase
Synonyms: prolyl oligopeptidase, D10Wsu136e, Pop
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 19072
VEGA: 10
HGNC: HGNC:9358
Homologene: 2042
Pogz
Name: pogo transposable element with ZNF domain
Synonyms: 9530006B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229584
Homologene: 9022
Bnc2
Name: basonuclin 2
Synonyms: 8430420F16Rik, 5031434M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242509
Homologene: 18243
Cenpc1
Name: centromere protein C1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12617
HGNC: HGNC:1854
Homologene: 1371
Ddx54
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
Synonyms: 2410015A15Rik, APR-5, DP97
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71990
Homologene: 5590
Akap9
Name: A kinase (PRKA) anchor protein (yotiao) 9
Synonyms: mei2-5, G1-448-15, 5730481H23Rik, AKAP450, repro12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Tanc2
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Synonyms: 5730590C14Rik, 3526402J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 77097
Homologene: 64680
Ncor2
Name: nuclear receptor co-repressor 2
Synonyms: SMRT, SMRTe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20602
HGNC: HGNC:7673
Homologene: 31370
Dmbx1
Name: diencephalon/mesencephalon homeobox 1
Synonyms: Mbx, Atx, Cdmx, Dmbx1, Otx3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 140477
Homologene: 15639
Ei24
Name: etoposide induced 2.4 mRNA
Synonyms: PIG8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 13663
Homologene: 3588
Cald1
Name: caldesmon 1
Synonyms: C920027I18Rik, 4833423D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 109624
HGNC: HGNC:1441
Homologene: 137254
Cpne6
Name: copine VI
Synonyms: neuronal copine
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 12891
HGNC: HGNC:2319
Homologene: 81815
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Scmh1
Name: sex comb on midleg homolog 1
Synonyms: Scml3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 29871
Homologene: 32146
Scpep1
Name: serine carboxypeptidase 1
Synonyms: 2410018F01Rik, Risc, 4833411K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 74617
Homologene: 41443
Usp6nl
Name: USP6 N-terminal like
Synonyms: TRE2NL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 98910
Homologene: 6879
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: 2210407G14Rik, Hapip, E530005C20Rik, LOC224126
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Zfhx2
Name: zinc finger homeobox 2
Synonyms: zfh-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239102
Homologene: 52657
Col4a4
Name: collagen, type IV, alpha 4
Synonyms: E130010M05Rik, [a]4(IV)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12829
HGNC: HGNC:2206
Homologene: 20071
Prf1
Name: perforin 1 (pore forming protein)
Synonyms: perforin, Pfp, Pfn, Prf-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 18646
VEGA: 10
HGNC: HGNC:9360
Homologene: 3698
Myof
Name: myoferlin
Synonyms: E030042N20Rik, Fer1l3, 2310051D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226101
VEGA: 19
HGNC: HGNC:3656
Homologene: 40882
Large2
Name: LARGE xylosyl- and glucuronyltransferase 2
Synonyms: 5730485C17Rik, Gyltl1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228366
Homologene: 27362
2610507B11Rik
Name: RIKEN cDNA 2610507B11 gene
Synonyms: E1, D11Bhm178e, D11Bhm179e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72503
Homologene: 34730
Mroh2b
Name: maestro heat-like repeat family member 2B
Synonyms: 4930455B06Rik, Heatr7b2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223825
VEGA: 15
Homologene: 128807
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC5, MUC9, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Ugt2b37
Name: UDP glucuronosyltransferase 2 family, polypeptide B37
Synonyms: 0610033E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 112417
Homologene: 137225
Slc4a10
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 94229
Homologene: 23340
Tns1
Name: tensin 1
Synonyms: 1200014E20Rik, E030037J05Rik, 1110018I21Rik, Tns, E030018G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 21961
Homologene: 11219
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: Dvwa, Vwa6, EG235580, 1110001D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 68553
Homologene: 130754
Tle5
Name: TLE family member 5, transcriptional modulator
Synonyms: Aes, Grg5, Grg, AES
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14797
VEGA: 10
HGNC: HGNC:307
Homologene: 879
Cd226
Name: CD226 antigen
Synonyms: Pta1, TLiSA1, DNAM-1, DNAM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225825
Homologene: 4787
Olfr1156
Name: olfactory receptor 1156
Synonyms: GA_x6K02T2Q125-49433499-49432537, MOR174-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258814
HGNC: HGNC:8351
Homologene: 72031
Capn9
Name: calpain 9
Synonyms: GC36, nCL-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 73647
HGNC: HGNC:1486
Homologene: 38208
Sphkap
Name: SPHK1 interactor, AKAP domain containing
Synonyms: A930009L15Rik, SKIP, 4930544G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 77629
Homologene: 18172
Kif28
Name: kinesin family member 28
Synonyms: LOC383592, Gm1305
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 383592
Homologene: 130945
Zer1
Name: zyg-11 related, cell cycle regulator
Synonyms: Zyg11bl, C230075L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227693
Homologene: 4621
Usp17lb
Name: ubiquitin specific peptidase 17-like B
Synonyms: Dub1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381944
Homologene: 131315
Akp3
Name: alkaline phosphatase 3, intestine, not Mn requiring
Synonyms: IAP, Akp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11648
Homologene: 134333
Olfr338
Name: olfactory receptor 338
Synonyms: MOR136-5, GA_x6K02T2NLDC-33070879-33071799
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258949
Homologene: 133647
Cd44
Name: CD44 antigen
Synonyms: Pgp-1, Ly-24, HERMES
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12505
HGNC: HGNC:1681
Homologene: 508
Inmt
Name: indolethylamine N-methyltransferase
Synonyms: Temt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 21743
HGNC: HGNC:6069
Homologene: 81752
Frmd3
Name: FERM domain containing 3
Synonyms: 4.1O, 9430066I12Rik, EPB41L4O, P410
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242506
Homologene: 16012
Acot5
Name: acyl-CoA thioesterase 5
Synonyms: PTE-Ic
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217698
Homologene: 77351
Anks1b
Name: ankyrin repeat and sterile alpha motif domain containing 1B
Synonyms: C030032C09Rik, Gm10937, LOC380650, AIDA-1b, E530015N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 77531
Homologene: 51570
Mrpl42
Name: mitochondrial ribosomal protein L42
Synonyms: HSPC204, MRP-L31, PTD007, Rpml31, 2900055D03Rik, 2700009F22Rik, D10Ertd322e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67270
VEGA: 10
Homologene: 12106
Acyp2
Name: acylphosphatase 2, muscle type
Synonyms: 2310004B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75572
HGNC: HGNC:180
Homologene: 41776
Psme2
Name: proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
Synonyms: PA28b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19188
HGNC: HGNC:9569
Homologene: 86889
Tmem213
Name: transmembrane protein 213
Synonyms: D630002J15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 77522
Homologene: 28553
Cept1
Name: choline/ethanolaminephosphotransferase 1
Synonyms: 9930118K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99712
Homologene: 81624
Spinkl
Name: serine protease inhibitor, Kazal type-like
Synonyms: 9530002K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 77424
VEGA: 18
Homologene: 128818
Gm6408
Name: predicted gene 6408
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 623198
Homologene: 86127
Olfr1438-ps1
Name: olfactory receptor 1438, pseudogene 1
Synonyms: GA_x6K02T2RE5P-2669245-2668277, MOR215-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258116
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 73,928,097 bp
  • T to A, chromosome 1 at 82,492,619 bp
  • T to C, chromosome 1 at 83,267,405 bp
  • T to A, chromosome 1 at 87,127,541 bp
  • T to C, chromosome 1 at 136,845,542 bp
  • A to T, chromosome 1 at 179,695,790 bp
  • G to T, chromosome 2 at 6,441,339 bp
  • A to G, chromosome 2 at 30,104,997 bp
  • A to G, chromosome 2 at 36,377,310 bp
  • A to T, chromosome 2 at 62,243,431 bp
  • A to T, chromosome 2 at 87,949,801 bp
  • C to T, chromosome 2 at 92,366,058 bp
  • A to T, chromosome 2 at 102,845,397 bp
  • A to G, chromosome 3 at 94,856,117 bp
  • A to T, chromosome 3 at 106,533,443 bp
  • T to C, chromosome 4 at 74,170,691 bp
  • C to T, chromosome 4 at 84,555,900 bp
  • G to T, chromosome 4 at 115,918,176 bp
  • T to A, chromosome 4 at 120,505,515 bp
  • A to G, chromosome 5 at 4,043,925 bp
  • A to T, chromosome 5 at 25,284,205 bp
  • T to A, chromosome 5 at 86,012,263 bp
  • A to C, chromosome 5 at 87,254,177 bp
  • G to T, chromosome 5 at 120,623,580 bp
  • A to G, chromosome 5 at 125,033,441 bp
  • A to G, chromosome 5 at 146,484,257 bp
  • A to T, chromosome 6 at 34,746,338 bp
  • A to G, chromosome 6 at 38,109,451 bp
  • A to T, chromosome 6 at 55,174,948 bp
  • A to C, chromosome 7 at 104,840,345 bp
  • A to T, chromosome 7 at 141,857,379 bp
  • A to G, chromosome 8 at 124,589,078 bp
  • A to G, chromosome 9 at 36,793,307 bp
  • A to T, chromosome 9 at 106,067,921 bp
  • T to A, chromosome 10 at 45,072,129 bp
  • A to G, chromosome 10 at 61,303,028 bp
  • T to C, chromosome 10 at 81,561,264 bp
  • C to T, chromosome 10 at 90,359,048 bp
  • T to C, chromosome 10 at 95,500,479 bp
  • C to T, chromosome 11 at 30,506,354 bp
  • G to T, chromosome 11 at 75,633,100 bp
  • T to C, chromosome 11 at 78,285,468 bp
  • T to C, chromosome 11 at 86,704,129 bp
  • A to G, chromosome 11 at 88,929,313 bp
  • G to A, chromosome 11 at 105,867,717 bp
  • A to G, chromosome 12 at 84,075,554 bp
  • A to G, chromosome 12 at 100,968,354 bp
  • A to G, chromosome 14 at 55,074,005 bp
  • T to C, chromosome 14 at 55,513,059 bp
  • A to G, chromosome 14 at 55,590,082 bp
  • A to G, chromosome 14 at 65,531,540 bp
  • T to A, chromosome 15 at 4,912,884 bp
  • T to A, chromosome 16 at 34,357,343 bp
  • A to G, chromosome 17 at 30,663,305 bp
  • C to A, chromosome 18 at 44,168,139 bp
  • T to C, chromosome 18 at 89,207,219 bp
  • C to T, chromosome 19 at 12,333,644 bp
  • C to A, chromosome 19 at 37,939,856 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5999 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044178-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.