Strain Name:
C57BL/6J-MtgxR6023Btlr
Stock Number:
044195-MU
Citation ID:
RRID:MMRRC_044195-MU
Other Names:
R6023 (G1)
Major Collection:

Gene Information

Atrn
Name: attractin
Synonyms: Mgca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11990
HGNC: HGNC:885
Homologene: 22542
Ap2b1
Name: adaptor-related protein complex 2, beta 1 subunit
Synonyms: 1300012O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71770
HGNC: HGNC:563
Homologene: 137384
Abcc8
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Synonyms: SUR1, Sur, D930031B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20927
HGNC: HGNC:59
Homologene: 68048
Kif11
Name: kinesin family member 11
Synonyms: Kifl1, Knsl1, Eg5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16551
VEGA: 19
HGNC: HGNC:6388
Homologene: 3322
Ctc1
Name: CTS telomere maintenance complex component 1
Synonyms: 1500010J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68964
Homologene: 11830
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: A430032G04Rik, D630005A10Rik, Bruce, apollon, A430040A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: A330049M09Rik, C130039F11Rik, SYNE-1, nesprin-1, enaptin165
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Vars
Name: valyl-tRNA synthetase
Synonyms: Vars2, Bat-6, D17H6S56E, Bat6, G7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22321
Homologene: 4587
Vps8
Name: VPS8 CORVET complex subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 209018
Homologene: 44592
Clec3a
Name: C-type lectin domain family 3, member a
Synonyms: Clecsf1, 1110019O10Rik, LOC330844
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 403395
HGNC: HGNC:2052
Homologene: 4205
Ercc8
Name: excision repaiross-complementing rodent repair deficiency, complementation group 8
Synonyms: B130065P18Rik, Csa, Ckn1, 2410022P04Rik, 2810431L23Rik, 4631412O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 71991
HGNC: HGNC:3439
Homologene: 62
Kel
Name: Kell blood group
Synonyms: CD238
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 23925
HGNC: HGNC:6308
Homologene: 362
Pfdn2
Name: prefoldin 2
Synonyms: ESTM27, W48336
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18637
HGNC: HGNC:8867
Homologene: 7887
Klk4
Name: kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)
Synonyms: KLK-L1, ESMP1, Prss17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56640
HGNC: HGNC:6365
Homologene: 55856
Cdh23
Name: cadherin 23 (otocadherin)
Synonyms: nmf252, bob, sals, mdfw, ahl, nmf181, USH1D, 4930542A03Rik, nmf112
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22295
Homologene: 11142
Ttn
Name: titin
Synonyms: D330041I19Rik, mdm, L56, connectin, 2310074I15Rik, 2310057K23Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Pcdhb11
Name: protocadherin beta 11
Synonyms: PcdhbK, Pcdhb5E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93882
Homologene: 62178
Aff3
Name: AF4/FMR2 family, member 3
Synonyms: Laf4, LAF-4, 3222402O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16764
HGNC: HGNC:6473
Homologene: 1718
Evc2
Name: EvC ciliary complex subunit 2
Synonyms: Ellis van Creveld syndrome 2, Lbn, limbin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68525
Homologene: 17117
Nav3
Name: neuron navigator 3
Synonyms: 4732483H20Rik, 9630020C08Rik, POMFIL1, steerin 3, Pomfil1p, unc53H3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 260315
Homologene: 56688
Got1l1
Name: glutamic-oxaloacetic transaminase 1-like 1
Synonyms: 1700083M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 76615
Homologene: 65045
Hcrtr2
Name: hypocretin (orexin) receptor 2
Synonyms: mOX2bR, mOXR2, mOX2aR, OX2r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 387285
HGNC: HGNC:4849
Homologene: 1168
Rnf112
Name: ring finger protein 112
Synonyms: Zfp179, neurolastin, bfp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22671
Homologene: 5176
Duox1
Name: dual oxidase 1
Synonyms: THOX1, 9930101G15Rik, LNOX1, NOXEF1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99439
HGNC: HGNC:3062
Homologene: 68136
Olfr1477
Name: olfactory receptor 1477
Synonyms: MOR202-10, GA_x6K02T2RE5P-3834960-3835907
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258691
Homologene: 110492
Naip1
Name: NLR family, apoptosis inhibitory protein 1
Synonyms: Birc1a, D13Lsd1, Naip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17940
VEGA: 13
HGNC: HGNC:7634
Homologene: 113589
Dpp6
Name: dipeptidylpeptidase 6
Synonyms: Peplb, Dpp-6, Rw, In(5)6H-p, B930011P16Rik, LOC384168
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13483
HGNC: HGNC:3010
Homologene: 22560
Trim67
Name: tripartite motif-containing 67
Synonyms: D130049O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330863
Homologene: 45699
Dhrs1
Name: dehydrogenase/reductase (SDR family) member 1
Synonyms: 1110029G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 52585
Homologene: 41696
Olfr339
Name: olfactory receptor 339
Synonyms: MOR136-3, GA_x6K02T2NLDC-33116096-33117025
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258951
Homologene: 133615
Prrt4
Name: proline-rich transmembrane protein 4
Synonyms: D330027H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 101359
Homologene: 46116
Lrrc74a
Name: leucine rich repeat containing 74A
Synonyms: Gm6772, Lrrc74
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 627607
VEGA: 12
Homologene: 19331
Krt7
Name: keratin 7
Synonyms: D15Wsu77e, Cytokeratin 7, Krt2-7, K7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110310
HGNC: HGNC:6445
Homologene: 4058
Luzp2
Name: leucine zipper protein 2
Synonyms: 9330154K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233271
Homologene: 45618
Olfr1212
Name: olfactory receptor 1212
Synonyms: GA_x6K02T2Q125-50437014-50437949, MOR233-17, MOR233-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258241
Homologene: 66154
Sh3tc1
Name: SH3 domain and tetratricopeptide repeats 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231147
Homologene: 10360
Olfr649
Name: olfactory receptor 649
Synonyms: GA_x6K02T2PBJ9-6924585-6923647, MOR31-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259057
Homologene: 74119
Cpz
Name: carboxypeptidase Z
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 242939
HGNC: HGNC:2333
Homologene: 2709
Thrb
Name: thyroid hormone receptor beta
Synonyms: TR beta, c-erbAbeta, T3R[b], T3Rbeta, Thrb1, Thrb2, Nr1a2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21834
Homologene: 36025
Dnajc25
Name: DnaJ heat shock protein family (Hsp40) member C25
Synonyms: 2010203O07Rik, 2010109C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72429
Homologene: 37883
Try4
Name: trypsin 4
Synonyms: 0910001B19Rik, Td
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 22074
HGNC: HGNC:9486
Homologene: 106639
Vmn1r9
Name: vomeronasal 1 receptor 9
Synonyms: V1rc30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171203
Homologene: 76459
Appl2
Name: adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
Synonyms: Dip3b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216190
Homologene: 10046
Olfr1342
Name: olfactory receptor 1342
Synonyms: MOR258-3, GA_x6K02T2QD9B-18856980-18857927
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258708
Homologene: 17357
Polr2h
Name: polymerase (RNA) II (DNA directed) polypeptide H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 245841
HGNC: HGNC:9195
Homologene: 4540
Sgms1
Name: sphingomyelin synthase 1
Synonyms: SMS1alpha2, SMS1alpha1, SMS1gamma, SMS1, Tmem23, 9530058O11Rik, SMS1beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 208449
Homologene: 27040
Glra1
Name: glycine receptor, alpha 1 subunit
Synonyms: nmf11, B230397M16Rik, oscillator, ot
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14654
HGNC: HGNC:4326
Homologene: 20083
Olfr566
Name: olfactory receptor 566
Synonyms: GA_x6K02T2PBJ9-5560696-5559746, MOR14-7P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258168
Homologene: 133721
Psg29
Name: pregnancy-specific glycoprotein 29
Synonyms: cea17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 114872
Homologene: 83380
Olfr837
Name: olfactory receptor 837
Synonyms: GA_x6K02T2PVTD-12873838-12874776, MOR152-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258558
Homologene: 115507
Ighv1-72
Name: immunoglobulin heavy variable 1-72
Synonyms: Gm16709
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 619916
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 38,218,370 bp
  • T to C, chromosome 1 at 171,356,751 bp
  • A to G, chromosome 2 at 36,421,511 bp
  • G to T, chromosome 2 at 76,735,400 bp
  • A to G, chromosome 2 at 88,958,715 bp
  • T to G, chromosome 2 at 122,337,684 bp
  • T to C, chromosome 2 at 131,020,980 bp
  • A to G, chromosome 4 at 59,013,752 bp
  • T to A, chromosome 4 at 118,690,074 bp
  • T to C, chromosome 5 at 27,723,547 bp
  • T to A, chromosome 5 at 35,512,578 bp
  • T to A, chromosome 5 at 35,706,951 bp
  • T to A, chromosome 5 at 37,348,616 bp
  • G to A, chromosome 6 at 29,176,453 bp
  • T to C, chromosome 6 at 41,303,421 bp
  • C to A, chromosome 6 at 41,697,475 bp
  • A to G, chromosome 6 at 57,071,254 bp
  • G to T, chromosome 7 at 17,210,512 bp
  • T to G, chromosome 7 at 43,884,058 bp
  • T to C, chromosome 7 at 46,108,419 bp
  • T to C, chromosome 7 at 55,058,067 bp
  • T to C, chromosome 7 at 102,856,962 bp
  • T to C, chromosome 7 at 104,189,673 bp
  • A to T, chromosome 8 at 27,199,904 bp
  • A to G, chromosome 8 at 114,418,143 bp
  • A to T, chromosome 8 at 124,815,104 bp
  • A to C, chromosome 9 at 19,137,725 bp
  • T to A, chromosome 9 at 76,230,604 bp
  • T to C, chromosome 10 at 5,443,223 bp
  • A to T, chromosome 10 at 60,465,542 bp
  • T to C, chromosome 10 at 83,648,529 bp
  • T to C, chromosome 10 at 109,823,515 bp
  • A to T, chromosome 11 at 55,533,853 bp
  • T to A, chromosome 11 at 61,449,729 bp
  • A to G, chromosome 11 at 69,022,607 bp
  • C to T, chromosome 11 at 83,335,398 bp
  • A to G, chromosome 12 at 86,758,606 bp
  • T to A, chromosome 12 at 115,757,912 bp
  • T to C, chromosome 13 at 100,426,186 bp
  • A to G, chromosome 13 at 108,178,577 bp
  • C to T, chromosome 14 at 18,011,209 bp
  • A to T, chromosome 14 at 55,743,670 bp
  • T to C, chromosome 15 at 101,412,397 bp
  • T to C, chromosome 16 at 20,719,026 bp
  • C to A, chromosome 16 at 21,461,238 bp
  • C to T, chromosome 17 at 35,001,609 bp
  • A to T, chromosome 17 at 74,654,377 bp
  • T to C, chromosome 18 at 37,422,925 bp
  • A to G, chromosome 19 at 13,502,703 bp
  • T to C, chromosome 19 at 32,124,373 bp
  • A to G, chromosome 19 at 37,390,710 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6023 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044195-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.