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Strain Name:
C57BL/6J-MtgxR6031Btlr/Mmmh
Stock Number:
044203-MU
Citation ID:
RRID:MMRRC_044203-MU
Other Names:
R6031 (G1)
Major Collection:

Strain Information

Atg7
Name: autophagy related 7
Synonyms: 1810013K23Rik, Apg7l
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74244
Homologene: 4662
Odf2l
Name: outer dense fiber of sperm tails 2-like
Synonyms: 4733401D09Rik, 9630045K08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 52184
Homologene: 12011
Thbs3
Name: thrombospondin 3
Synonyms: Thbs-3, TSP3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 21827
Homologene: 5159
Scn8a
Name: sodium channel, voltage-gated, type VIII, alpha
Synonyms: med, seal, motor end-plate disease, nmf2, ataxia 3, mnd2, mnd-2, C630029C19Rik, nmf58, NaCh6, Nav1.6, nmf335, NMF335, nur14
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20273
Homologene: 7927
Numa1
Name: nuclear mitotic apparatus protein 1
Synonyms: 6720401E04Rik, NuMA
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101706
HGNC: HGNC:8059
Homologene: 38150
Ndc80
Name: NDC80 kinetochore complex component
Synonyms: HEC1, 2610020P18Rik, Kntc2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67052
VEGA: 17
Homologene: 38141
Ascc3
Name: activating signal cointegrator 1 complex subunit 3
Synonyms: ASC1p200, B630009I04Rik, Helic1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 77987
VEGA: 10
Homologene: 4973
Iars1
Name: isoleucyl-tRNA synthetase 1
Synonyms: E430001P04Rik, 2510016L12Rik, Iars
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105148
HGNC: HGNC:5330
Homologene: 5325
Camsap2
Name: calmodulin regulated spectrin-associated protein family, member 2
Synonyms: 1600013L13Rik, 4930541M15Rik, Camsap1l1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67886
Homologene: 18927
Ufl1
Name: UFM1 specific ligase 1
Synonyms: Rcad, Maxer, 1810074P20Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67490
Homologene: 9093
Asb6
Name: ankyrin repeat and SOCS box-containing 6
Synonyms: 2510004M11Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72323
Homologene: 9895
Pdik1l
Name: PDLIM1 interacting kinase 1 like
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230809
Homologene: 36977
Ntm
Name: neurotrimin
Synonyms: 6230410L23Rik, B230210G24Rik, Hnt
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235106
Homologene: 41139
Cpt1a
Name: carnitine palmitoyltransferase 1a, liver
Synonyms: CPTI, L-CPT I, Cpt1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12894
VEGA: 19
HGNC: HGNC:2328
Homologene: 1413
Arhgap23
Name: Rho GTPase activating protein 23
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 58996
Homologene: 104145
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 1810042B05Rik, Coh1, C330002D13Rik, 2310042E16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 236266
HGNC: HGNC:428
Homologene: 49406
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230895
Homologene: 15583
Hyls1
Name: HYLS1, centriolar and ciliogenesis associated
Synonyms: 3010015K02Rik, hydrolethalus syndrome 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76832
Homologene: 82283
Gfpt1
Name: glutamine fructose-6-phosphate transaminase 1
Synonyms: GFAT, GFA, GFAT1, 2810423A18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14583
HGNC: HGNC:4241
Homologene: 68220
Nop2
Name: NOP2 nucleolar protein
Synonyms: 120kDa, Nol1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 110109
HGNC: HGNC:7867
Homologene: 135865
Hspbp1
Name: HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
Synonyms: 1500019G21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66245
Homologene: 40827
Med23
Name: mediator complex subunit 23
Synonyms: ESTM7, 3000002A17Rik, X83317, Crsp3, Sur2, sno
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70208
HGNC: HGNC:2372
Homologene: 3552
Tlr3
Name: toll-like receptor 3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 142980
Homologene: 20696
Gfi1b
Name: growth factor independent 1B
Synonyms: Gfi-1B
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14582
HGNC: HGNC:4238
Homologene: 31223
Ttn
Name: titin
Synonyms: connectin, L56, 1100001C23Rik, mdm, 2310036G12Rik, D830007G01Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Uggt2
Name: UDP-glucose glycoprotein glucosyltransferase 2
Synonyms: 3110001A05Rik, 1810064L21Rik, 3110027P15Rik, A230065J02Rik, Ugcgl2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66435
Homologene: 56875
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC234973, LOC382129, D430038H04Rik, 9430076A06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Ccdc125
Name: coiled-coil domain containing 125
Synonyms: 5830436D01Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76041
VEGA: 13
Homologene: 27932
Add2
Name: adducin 2
Synonyms: 2900072M03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11519
HGNC: HGNC:244
Homologene: 1221
Efr3b
Name: EFR3 homolog B
Synonyms: C030014M07Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 668212
VEGA: 12
Homologene: 66195
Zfp943
Name: zinc finger prtoein 943
Synonyms: 4930432O21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74670
Homologene: 134342
Wdr53
Name: WD repeat domain 53
Synonyms: 1500002B03Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 68980
Homologene: 15591
Cpd
Name: carboxypeptidase D
Synonyms: D830034L15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12874
HGNC: HGNC:2301
Homologene: 999
Trpm8
Name: transient receptor potential cation channel, subfamily M, member 8
Synonyms: CMR1, TRPP8, Trp-p8
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 171382
Homologene: 23433
Gria1
Name: glutamate receptor, ionotropic, AMPA1 (alpha 1)
Synonyms: GluR1, GluR-A, Glr-1, Glur-1, Glur1, GluRA, Glr1, 2900051M01Rik, HIPA1, GluA1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14799
HGNC: HGNC:4571
Homologene: 20226
Zfp93
Name: zinc finger protein 93
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22755
Homologene: 117959
Disp2
Name: dispatched RND transporter family member 2
Synonyms: DispB, B230210L08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 214240
Homologene: 24916
Jade2
Name: jade family PHD finger 2
Synonyms: 1200017K05Rik, Phf15
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76901
Homologene: 9082
Nrxn1
Name: neurexin I
Synonyms: alpha-latrotoxin receptor (calcium-dependent), neurexin I beta, neurexin I alpha, neurexin I beta, neurexin I beta, neurexin I alpha, neurexin I alpha, 1700062G21Rik, A230068P09Rik, 9330127H16Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18189
HGNC: HGNC:8008
Homologene: 21005
Pcdhb19
Name: protocadherin beta 19
Synonyms: Pcdhb11, PcdhbS
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93890
Homologene: 128411
Crocc
Name: ciliary rootlet coiled-coil, rootletin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230872
Homologene: 16811
Ccdc63
Name: coiled-coil domain containing 63
Synonyms: 4921511C16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330188
Homologene: 45136
Ipo4
Name: importin 4
Synonyms: 8430408O15Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75751
Homologene: 5835
Or10ak11
Name: olfactory receptor family 10 subfamily AK member 11
Synonyms: GA_x6K02T2QD9B-18703033-18703986, MOR259-11, MOR259-6, Olfr1333
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 258265
Homologene: 134082
Or2ag2
Name: olfactory receptor family 2 subfamily AG member 2
Synonyms: GA_x6K02T2PBJ9-9271198-9270248, MOR283-11, Olfr706
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258350
Homologene: 133646
Zc3h6
Name: zinc finger CCCH type containing 6
Synonyms: 4631426G04Rik, 4833425H18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 78751
Homologene: 35328
Or6ae1
Name: olfactory receptor family 6 subfamily AE member 1
Synonyms: GA_x6K02T2PBJ9-42315125-42314187, MOR103-5, Olfr522
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258954
Homologene: 62435
Or4a39
Name: olfactory receptor family 4subfamily A member 39
Synonyms: GA_x6K02T2Q125-50849945-50848998, MOR231-11, Olfr1238
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258786
Homologene: 128093
Vmn1r9
Name: vomeronasal 1 receptor 9
Synonyms: V1rc30
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171203
Homologene: 76459
Akr1b1
Name: aldo-keto reductase family 1 member B
Synonyms: Ahr-1, Ahr1, Aldor1, Aldr1, ALR2, AR, Akr1b3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11677
HGNC: HGNC:381
Homologene: 133743
Fam98a
Name: family with sequence similarity 98, member A
Synonyms: 2810405J04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72722
Homologene: 41042
Creb3l2
Name: cAMP responsive element binding protein 3-like 2
Synonyms: BBF2H7, C530025K05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 208647
Homologene: 18690
Mcub
Name: modifier of curly bare
Synonyms: 9030408N13Rik, Ccdc109b
Type: Gene
Species: Mouse
Chromosome: 3
Or5ac17
Name: olfactory receptor family 5 subfamily AC member 17
Synonyms: GA_x54KRFPKG5P-55430495-55429569, MOR182-14, Olfr199
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 404310
Homologene: 37011
Frmd3
Name: FERM domain containing 3
Synonyms: EPB41L4O, P410, 4.1O, 9430066I12Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242506
Homologene: 16012
Vgll3
Name: vestigial like family member 3
Synonyms: 1700110N18Rik, Vito-2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 73569
VEGA: 16
Homologene: 53442
Wdr81
Name: WD repeat domain 81
Synonyms: shakey 5, MGC32441, nur5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192652
Homologene: 13983
Pacc1
Name: proton activated chloride channel 1
Synonyms: 2310028N02Rik, Tmem206
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66950
Homologene: 10097
Galt
Name: galactose-1-phosphate uridyl transferase
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14430
HGNC: HGNC:4135
Homologene: 126
Or6c203
Name: olfactory receptor family 6 subfamily C member 203
Synonyms: GA_x6K02T2PULF-10860457-10859522, MOR114-3, Olfr772
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 257666
Homologene: 123776
Rnf208
Name: ring finger protein 208
Synonyms: 1110061N23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68846
Homologene: 32752
Rnf113a2
Name: ring finger protein 113A2
Synonyms: 2310020H19Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 66381
Homologene: 133824
Gatb
Name: glutamyl-tRNA amidotransferase subunit B
Synonyms: 9430026F02Rik, Pet112l, Pet112
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229487
HGNC: HGNC:8849
Homologene: 3357
RP23-145I16.3
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 88,354,469 bp
  • A to T, chromosome 1 at 136,280,438 bp
  • A to G, chromosome 1 at 191,340,840 bp
  • A to C, chromosome 2 at 25,243,764 bp
  • G to A, chromosome 2 at 28,613,808 bp
  • A to G, chromosome 2 at 30,824,195 bp
  • A to T, chromosome 2 at 76,830,597 bp
  • T to A, chromosome 2 at 89,406,972 bp
  • G to T, chromosome 2 at 118,789,794 bp
  • A to G, chromosome 2 at 128,967,812 bp
  • T to C, chromosome 3 at 85,613,511 bp
  • T to A, chromosome 3 at 89,218,094 bp
  • A to G, chromosome 3 at 129,926,389 bp
  • A to G, chromosome 3 at 145,139,863 bp
  • A to G, chromosome 4 at 25,278,038 bp
  • G to A, chromosome 4 at 41,757,202 bp
  • T to C, chromosome 4 at 74,187,451 bp
  • A to T, chromosome 4 at 118,830,391 bp
  • A to G, chromosome 4 at 134,279,041 bp
  • A to T, chromosome 4 at 141,034,357 bp
  • A to C, chromosome 4 at 145,168,509 bp
  • T to C, chromosome 5 at 122,129,736 bp
  • A to C, chromosome 6 at 34,312,674 bp
  • A to T, chromosome 6 at 37,334,434 bp
  • A to G, chromosome 6 at 57,071,173 bp
  • A to T, chromosome 6 at 85,622,955 bp
  • A to G, chromosome 6 at 86,098,673 bp
  • C to A, chromosome 6 at 87,086,320 bp
  • T to A, chromosome 6 at 114,671,233 bp
  • T to C, chromosome 6 at 125,133,566 bp
  • A to T, chromosome 7 at 4,663,466 bp
  • G to T, chromosome 7 at 24,276,300 bp
  • T to A, chromosome 7 at 102,012,012 bp
  • C to T, chromosome 7 at 106,885,927 bp
  • A to T, chromosome 7 at 140,162,809 bp
  • A to T, chromosome 7 at 142,376,714 bp
  • A to G, chromosome 8 at 45,398,528 bp
  • T to A, chromosome 9 at 15,988,492 bp
  • T to C, chromosome 9 at 21,275,269 bp
  • A to C, chromosome 9 at 29,009,375 bp
  • G to A, chromosome 9 at 35,561,184 bp
  • C to T, chromosome 10 at 24,903,748 bp
  • C to T, chromosome 10 at 50,842,183 bp
  • A to G, chromosome 10 at 129,174,355 bp
  • G to T, chromosome 11 at 51,826,586 bp
  • A to G, chromosome 11 at 57,217,782 bp
  • A to T, chromosome 11 at 75,447,869 bp
  • T to C, chromosome 11 at 76,790,888 bp
  • A to T, chromosome 11 at 97,476,139 bp
  • A to G, chromosome 12 at 3,967,106 bp
  • T to C, chromosome 12 at 84,417,990 bp
  • T to C, chromosome 13 at 49,705,831 bp
  • C to T, chromosome 13 at 100,684,369 bp
  • G to A, chromosome 14 at 55,632,139 bp
  • A to T, chromosome 14 at 119,070,826 bp
  • T to A, chromosome 15 at 35,471,968 bp
  • A to T, chromosome 15 at 100,983,984 bp
  • T to A, chromosome 16 at 32,256,718 bp
  • T to C, chromosome 16 at 59,215,933 bp
  • T to A, chromosome 16 at 65,839,481 bp
  • T to C, chromosome 17 at 8,995,252 bp
  • C to T, chromosome 17 at 21,993,376 bp
  • T to C, chromosome 17 at 71,511,488 bp
  • A to G, chromosome 17 at 75,539,432 bp
  • T to C, chromosome 17 at 90,588,790 bp
  • A to T, chromosome 18 at 37,497,723 bp
  • T to A, chromosome 19 at 3,371,556 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6031 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044203-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.