Strain Name:
C57BL/6J-MtgxR6033Btlr
Stock Number:
044205-MU
Citation ID:
RRID:MMRRC_044205-MU
Other Names:
R6033 (G1)
Major Collection:

Gene Information

Ubn2
Name: ubinuclein 2
Synonyms: 2900060J04Rik, 6030408G03Rik, D130059P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320538
Homologene: 45564
Slc6a5
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Synonyms: Glyt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 104245
Homologene: 37901
Cnmd
Name: chondromodulin
Synonyms: Chondromodulin 1, ChM-I, Bricd3, Chmd, Lect1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16840
Homologene: 5095
Manba
Name: mannosidase, beta A, lysosomal
Synonyms: Bmn, 2410030O07Rik, B930014J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 110173
HGNC: HGNC:6831
Homologene: 4317
Prkd2
Name: protein kinase D2
Synonyms: PKD2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101540
Homologene: 9516
Drosha
Name: drosha, ribonuclease type III
Synonyms: 1110013A17Rik, Etohi2, Rnasen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14000
Homologene: 8293
Zfp280d
Name: zinc finger protein 280D
Synonyms: Suhw4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235469
Homologene: 17151
Slc45a4
Name: solute carrier family 45, member 4
Synonyms: 9330175B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 106068
Homologene: 69908
Taf2
Name: TATA-box binding protein associated factor 2
Synonyms: TAFII150, CIF150, TAF2B, 4732460C16Rik, 150kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 319944
VEGA: 15
Homologene: 31137
Afg3l2
Name: AFG3-like AAA ATPase 2
Synonyms: 2310036I02Rik, par, Emv66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 69597
VEGA: 18
HGNC: HGNC:315
Homologene: 4947
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: chromatin remodeling factor, 8030453L17Rik, E430018P19Rik, KMT2H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 192195
Homologene: 10225
Adgrl1
Name: adhesion G protein-coupled receptor L1
Synonyms: Lec2, lectomedin-2, 2900070I05Rik, Lphn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330814
Homologene: 8951
Zfp281
Name: zinc finger protein 281
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226442
Homologene: 8270
Gm6712
Name: predicted gene 6712
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100862203
Zbtb2
Name: zinc finger and BTB domain containing 2
Synonyms: LOC381990
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 381990
VEGA: 10
Homologene: 10837
Jaml
Name: junction adhesion molecule like
Synonyms: LOC270152, Amica1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270152
Homologene: 17708
Alas1
Name: aminolevulinic acid synthase 1
Synonyms: 5-aminolevulinate synthase, succinyl-CoA: glycine C-succinyl transferase, Alas-1, ALAS-N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11655
HGNC: HGNC:396
Homologene: 55478
Incenp
Name: inner centromere protein
Synonyms: 2700067E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16319
VEGA: 19
HGNC: HGNC:6058
Homologene: 9624
Dph1
Name: diphthamide biosynthesis 1
Synonyms: Ovca1, 4930488F09Rik, Dph2l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 116905
HGNC: HGNC:3003
Homologene: 1059
1700125H20Rik
Name: RIKEN cDNA 1700125H20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 73634
Homologene: 18763
Alox12e
Name: arachidonate lipoxygenase, epidermal
Synonyms: 8-LOX, e-LOX1, Alox12-ps1, Aloxe, Alox12-ps2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11685
Homologene: 105868
Grb7
Name: growth factor receptor bound protein 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14786
HGNC: HGNC:4567
Homologene: 3881
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Kcp
Name: kielin/chordin-like protein
Synonyms: LOC333088, KCP, Crim2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 333088
Homologene: 87817
Tgm5
Name: transglutaminase 5
Synonyms: 2310007C07Rik, TGx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74176
Homologene: 20899
Tmed4
Name: transmembrane p24 trafficking protein 4
Synonyms: 1110014L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103694
Homologene: 5308
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Unc80
Name: unc-80, NALCN activator
Synonyms: C230061B10Rik, C030018G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329178
Homologene: 122243
Fhod1
Name: formin homology 2 domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234686
Homologene: 136406
Taar2
Name: trace amine-associated receptor 2
Synonyms: Gpr58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 209512
HGNC: HGNC:4514
Homologene: 110760
Ccdc150
Name: coiled-coil domain containing 150
Synonyms: 4930511H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78016
Homologene: 15814
Hivep1
Name: human immunodeficiency virus type I enhancer binding protein 1
Synonyms: Cryabp1, alphaA-CRYBP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110521
VEGA: 13
HGNC: HGNC:4920
Homologene: 1596
Erich6
Name: glutamate rich 6
Synonyms: 4932431H17Rik, Fam194a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 545527
Homologene: 65043
Vmn2r72
Name: vomeronasal 2, receptor 72
Synonyms: EG244114, Vmn2r72-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244114
Homologene: 115466
Slco6c1
Name: solute carrier organic anion transporter family, member 6c1
Synonyms: 4933404A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74441
Homologene: 65259
Ica1
Name: islet cell autoantigen 1
Synonyms: ICA69, 69kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 15893
HGNC: HGNC:5343
Homologene: 7777
Igbp1b
Name: immunoglobulin (CD79A) binding protein 1b
Synonyms: alpha4-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 50540
Homologene: 75049
Nlrp10
Name: NLR family, pyrin domain containing 10
Synonyms: 6430548I20Rik, Pynod, Nalp10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244202
Homologene: 18468
Prss36
Name: protease, serine 36
Synonyms: polyserase-2, C330007D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 77613
Homologene: 18303
Myrfl
Name: myelin regulatory factor-like
Synonyms: LOC237558, Gm239
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237558
VEGA: 10
Homologene: 88588
Homer2
Name: homer scaffolding protein 2
Synonyms: Vesl-2, Cupidin, CPD, 9330120H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26557
Homologene: 3560
Ncan
Name: neurocan
Synonyms: Tgfbit, Cspg3, Cspg3-rs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 13004
HGNC: HGNC:2465
Homologene: 3229
Slc46a1
Name: solute carrier family 46, member 1
Synonyms: 1110002C08Rik, D11Ertd18e, HCP1, heme carrier protein 1, PCFT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 52466
Homologene: 41693
Ttll6
Name: tubulin tyrosine ligase-like family, member 6
Synonyms: t8130b59, 4932418K24Rik, D11Moh43e, D11Moh44e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237930
Homologene: 18229
Olfr1040
Name: olfactory receptor 1040
Synonyms: GA_x6K02T2Q125-47615732-47614791, MOR185-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 404323
Homologene: 79382
Zbtb24
Name: zinc finger and BTB domain containing 24
Synonyms: ZNF450
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 268294
VEGA: 10
Homologene: 8870
Tmem156
Name: transmembrane protein 156
Synonyms: LOC243025
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243025
Homologene: 49811
Ncoa4-ps
Name: nuclear receptor coactivator 4, pseudogene
Synonyms: Gm6768
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 627557
VEGA: 12
Arhgap8
Name: Rho GTPase activating protein 8
Synonyms: 3110043J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 73167
Homologene: 23645
Npas2
Name: neuronal PAS domain protein 2
Synonyms: MOP4, bHLHe9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18143
HGNC: HGNC:7895
Homologene: 1887
Glra1
Name: glycine receptor, alpha 1 subunit
Synonyms: ot, oscillator, B230397M16Rik, nmf11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14654
HGNC: HGNC:4326
Homologene: 20083
Ifna12
Name: interferon alpha 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242519
HGNC: HGNC:5425
Homologene: 68536
Prr3
Name: proline-rich polypeptide 3
Synonyms: CAT56, 4930540G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 75210
Homologene: 11897
Nsg2
Name: neuron specific gene family member 2
Synonyms: P19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18197
Homologene: 7451
Cmtm8
Name: CKLF-like MARVEL transmembrane domain containing 8
Synonyms: 2700018N07Rik, Cklfsf8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70031
VEGA: 9
Homologene: 12345
Gm21972
Name: predicted gene 21972
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Eid3
Name: EP300 interacting inhibitor of differentiation 3
Synonyms: 1700027M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66341
Homologene: 81651
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 39,338,180 bp
  • G to T, chromosome 1 at 54,285,628 bp
  • A to T, chromosome 1 at 66,473,260 bp
  • T to C, chromosome 1 at 86,137,095 bp
  • C to T, chromosome 1 at 97,081,316 bp
  • T to C, chromosome 1 at 136,626,726 bp
  • C to T, chromosome 2 at 76,726,827 bp
  • A to T, chromosome 2 at 86,146,269 bp
  • T to C, chromosome 2 at 121,070,729 bp
  • A to G, chromosome 3 at 58,623,201 bp
  • T to C, chromosome 3 at 88,985,019 bp
  • T to C, chromosome 3 at 135,549,261 bp
  • T to C, chromosome 4 at 88,602,917 bp
  • A to T, chromosome 5 at 65,075,621 bp
  • T to A, chromosome 6 at 8,630,799 bp
  • C to T, chromosome 6 at 29,493,194 bp
  • T to A, chromosome 6 at 38,470,224 bp
  • T to C, chromosome 6 at 138,658,209 bp
  • C to T, chromosome 7 at 16,865,714 bp
  • T to C, chromosome 7 at 49,959,351 bp
  • A to C, chromosome 7 at 81,618,679 bp
  • A to T, chromosome 7 at 85,737,929 bp
  • A to T, chromosome 7 at 108,924,577 bp
  • A to C, chromosome 7 at 120,071,647 bp
  • T to C, chromosome 7 at 127,934,567 bp
  • T to C, chromosome 8 at 70,112,590 bp
  • T to A, chromosome 8 at 83,918,922 bp
  • T to C, chromosome 8 at 105,336,434 bp
  • G to A, chromosome 9 at 45,088,710 bp
  • T to A, chromosome 9 at 72,329,137 bp
  • A to G, chromosome 9 at 106,241,204 bp
  • T to C, chromosome 9 at 114,796,073 bp
  • A to G, chromosome 10 at 4,368,599 bp
  • A to T, chromosome 10 at 23,940,976 bp
  • T to C, chromosome 10 at 41,464,401 bp
  • T to A, chromosome 10 at 82,867,653 bp
  • A to T, chromosome 10 at 116,849,101 bp
  • A to T, chromosome 11 at 6,274,491 bp
  • G to A, chromosome 11 at 32,055,058 bp
  • A to G, chromosome 11 at 55,527,419 bp
  • C to T, chromosome 11 at 70,316,013 bp
  • C to T, chromosome 11 at 75,191,197 bp
  • T to C, chromosome 11 at 78,466,007 bp
  • A to G, chromosome 11 at 85,178,372 bp
  • T to C, chromosome 11 at 96,134,887 bp
  • C to T, chromosome 11 at 98,455,197 bp
  • A to G, chromosome 12 at 119,261,740 bp
  • A to G, chromosome 13 at 42,157,107 bp
  • T to C, chromosome 14 at 79,661,505 bp
  • G to A, chromosome 15 at 12,925,999 bp
  • A to C, chromosome 15 at 55,058,901 bp
  • G to A, chromosome 15 at 73,581,976 bp
  • A to G, chromosome 15 at 84,741,925 bp
  • T to A, chromosome 17 at 17,294,416 bp
  • A to T, chromosome 17 at 35,978,624 bp
  • G to T, chromosome 18 at 67,421,259 bp
  • C to T, chromosome 19 at 9,872,697 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6033 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044205-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.