Strain Name:
C57BL/6J-MtgxR6061Btlr
Stock Number:
044226-MU
Citation ID:
RRID:MMRRC_044226-MU
Other Names:
R6061 (G1)
Major Collection:

Gene Information

Wnt5b
Name: wingless-type MMTV integration site family, member 5B
Synonyms: Wnt-5b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 22419
Homologene: 22530
Ptx3
Name: pentraxin related gene
Synonyms: TSG-14, pentraxin 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19288
HGNC: HGNC:9692
Homologene: 7500
Thbs4
Name: thrombospondin 4
Synonyms: TSP4, TSP-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 21828
Homologene: 20691
Ctnnal1
Name: catenin (cadherin associated protein), alpha-like 1
Synonyms: ACRP, Catnal1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 54366
HGNC: HGNC:2512
Homologene: 2815
Tiparp
Name: TCDD-inducible poly(ADP-ribose) polymerase
Synonyms: PARP-7, DDF1, PARP7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99929
Homologene: 9167
Ptpn3
Name: protein tyrosine phosphatase, non-receptor type 3
Synonyms: PTP-H1, PTPCL, 9530011I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 545622
HGNC: HGNC:9655
Homologene: 74451
Prkca
Name: protein kinase C, alpha
Synonyms: Pkca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18750
HGNC: HGNC:9393
Homologene: 55679
Med27
Name: mediator complex subunit 27
Synonyms: 2310042P07Rik, Crsp8, D2Ertd434e, 1500015J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68975
HGNC: HGNC:2377
Homologene: 3152
Xdh
Name: xanthine dehydrogenase
Synonyms: xanthine oxidase, Xor, Xox-1, Xox1, XO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22436
VEGA: 17
Homologene: 324
Rfx2
Name: regulatory factor X, 2 (influences HLA class II expression)
Synonyms: 5430432H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 19725
VEGA: 17
HGNC: HGNC:9983
Homologene: 30980
Glipr1l1
Name: GLI pathogenesis-related 1 like 1
Synonyms: 1700011E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 69286
VEGA: 10
Homologene: 83452
Rhpn2
Name: rhophilin, Rho GTPase binding protein 2
Synonyms: D7Ertd784e, 1300002E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 52428
Homologene: 12407
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225115
Homologene: 25090
Plagl1
Name: pleiomorphic adenoma gene-like 1
Synonyms: Zac1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22634
HGNC: HGNC:9046
Homologene: 31401
Pkd2l2
Name: polycystic kidney disease 2-like 2
Synonyms: Polycystin - L2, TRPP5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 53871
VEGA: 18
HGNC: HGNC:9012
Homologene: 22812
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: Dnahc14, A230079K17Rik, Gm980, LOC381311
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Nav3
Name: neuron navigator 3
Synonyms: unc53H3, 9630020C08Rik, Pomfil1p, POMFIL1, steerin 3, 4732483H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 260315
Homologene: 56688
Cyp2j11
Name: cytochrome P450, family 2, subfamily j, polypeptide 11
Synonyms: Cyp2j11-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100066
Homologene: 133819
Cdsn
Name: corneodesmosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 386463
HGNC: HGNC:1802
Pear1
Name: platelet endothelial aggregation receptor 1
Synonyms: 3110045G13Rik, Jedi-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 73182
Homologene: 12492
Gprc6a
Name: G protein-coupled receptor, family C, group 6, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 210198
VEGA: 10
Homologene: 17529
Rab3d
Name: RAB3D, member RAS oncogene family
Synonyms: C130057E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19340
HGNC: HGNC:9779
Homologene: 20902
A2ml1
Name: alpha-2-macroglobulin like 1
Synonyms: Ovos2, BC048546
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232400
Homologene: 45969
Vmn2r85
Name: vomeronasal 2, receptor 85
Synonyms: EG623734
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 623734
Homologene: 129606
Phf19
Name: PHD finger protein 19
Synonyms: 3321402G02Rik, 3110009G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74016
Homologene: 12524
Ddx60
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234311
Homologene: 23031
Ifi205
Name: interferon activated gene 205
Synonyms: D3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226695
HGNC: HGNC:5395
Homologene: 115929
Doxl2
Name: diamine oxidase-like protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243376
Homologene: 19443
Serpinb6b
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6b
Synonyms: NK13, ovalbumin, Spi12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20708
HGNC: HGNC:8950
Homologene: 22633
Mocs1
Name: molybdenum cofactor synthesis 1
Synonyms: 3110045D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56738
HGNC: HGNC:7190
Homologene: 4343
Olfr569
Name: olfactory receptor 569
Synonyms: GA_x6K02T2PBJ9-5599295-5598351, MOR30-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259092
Homologene: 17500
Olfr138
Name: olfactory receptor 138
Synonyms: Olfr89, GA_x6K02T2PSCP-2718585-2719523, MOR256-40P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 170648
Homologene: 119758
Zfp526
Name: zinc finger protein 526
Synonyms: D030024H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210172
Homologene: 18447
Gm4353
Name: predicted gene 4353
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043313
VEGA: 7
Vmn2r71
Name: vomeronasal 2, receptor 71
Synonyms: EG233445
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233445
Homologene: 115466
Olfr996
Name: olfactory receptor 996
Synonyms: MOR175-4, GA_x6K02T2Q125-47058060-47059004
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258429
Homologene: 85934
Olfr38
Name: olfactory receptor 38
Synonyms: MOR257-2, GA_x6K02T2P3E9-4797841-4796888, 18A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258988
HGNC: HGNC:8246
Homologene: 72050
Fhit
Name: fragile histidine triad gene
Synonyms: Fra14A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 14198
HGNC: HGNC:3701
Homologene: 21661
Vps9d1
Name: VPS9 domain containing 1
Synonyms: 2410004N05Rik, 1300018I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72325
Homologene: 21021
Mrpl11
Name: mitochondrial ribosomal protein L11
Synonyms: 2410001P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66419
VEGA: 19
Homologene: 6768
Phc3
Name: polyhomeotic 3
Synonyms: E030046K01Rik, HPH3, EDR3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 241915
Homologene: 69390
Olfr668
Name: olfactory receptor 668
Synonyms: MOR34-3, GA_x6K02T2PBJ9-7554614-7553658
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259061
Homologene: 64947
Speer3
Name: spermatogenesis associated glutamate (E)-rich protein 3
Synonyms: SPEER-3, 4933405P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71026
Homologene: 69402
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 174,027,264 bp
  • C to T, chromosome 1 at 181,709,051 bp
  • T to A, chromosome 2 at 29,509,441 bp
  • T to A, chromosome 2 at 34,897,117 bp
  • T to A, chromosome 2 at 85,579,542 bp
  • T to A, chromosome 3 at 30,914,529 bp
  • T to C, chromosome 3 at 65,553,243 bp
  • A to G, chromosome 3 at 66,224,709 bp
  • A to G, chromosome 3 at 87,755,931 bp
  • T to C, chromosome 4 at 56,812,349 bp
  • C to T, chromosome 4 at 57,248,681 bp
  • T to A, chromosome 4 at 96,348,616 bp
  • G to A, chromosome 5 at 13,794,691 bp
  • A to T, chromosome 6 at 42,762,965 bp
  • A to C, chromosome 6 at 48,976,601 bp
  • A to G, chromosome 6 at 119,433,642 bp
  • A to C, chromosome 6 at 128,568,712 bp
  • C to T, chromosome 7 at 25,226,332 bp
  • T to A, chromosome 7 at 35,376,211 bp
  • T to A, chromosome 7 at 85,619,274 bp
  • C to A, chromosome 7 at 102,887,951 bp
  • C to T, chromosome 7 at 104,925,392 bp
  • T to A, chromosome 7 at 116,084,269 bp
  • T to A, chromosome 8 at 62,023,241 bp
  • A to T, chromosome 8 at 123,245,671 bp
  • T to C, chromosome 9 at 21,910,519 bp
  • G to T, chromosome 10 at 13,127,895 bp
  • A to T, chromosome 10 at 51,615,811 bp
  • A to T, chromosome 10 at 109,866,984 bp
  • C to T, chromosome 10 at 112,076,170 bp
  • T to C, chromosome 10 at 130,425,662 bp
  • A to G, chromosome 11 at 108,057,845 bp
  • A to G, chromosome 13 at 32,977,994 bp
  • A to G, chromosome 13 at 92,751,795 bp
  • T to C, chromosome 14 at 9,573,435 bp
  • A to G, chromosome 17 at 35,554,906 bp
  • A to G, chromosome 17 at 38,274,881 bp
  • T to C, chromosome 17 at 49,450,313 bp
  • A to G, chromosome 17 at 56,777,473 bp
  • T to C, chromosome 17 at 73,921,347 bp
  • T to G, chromosome 18 at 5,106,724 bp
  • T to C, chromosome 18 at 34,430,689 bp
  • C to T, chromosome 19 at 4,963,369 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6061 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044226-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.