Strain Name:
C57BL/6J-MtgxR6073Btlr
Stock Number:
044234-MU
Citation ID:
RRID:MMRRC_044234-MU
Other Names:
R6073 (G1)
Major Collection:

Gene Information

Myo10
Name: myosin X
Synonyms: myosin-X, D15Ertd600e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 17909
HGNC: HGNC:7593
Homologene: 36328
Cd74
Name: CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
Synonyms: Ii, CLIP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 16149
VEGA: 18
HGNC: HGNC:1697
Homologene: 3209
Ntrk1
Name: neurotrophic tyrosine kinase, receptor, type 1
Synonyms: Tkr, TrkA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18211
HGNC: HGNC:8031
Homologene: 1898
Kcnj5
Name: potassium inwardly-rectifying channel, subfamily J, member 5
Synonyms: GIRK4, Kir3.4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 16521
VEGA: 9
HGNC: HGNC:6266
Homologene: 20248
Epb41l2
Name: erythrocyte membrane protein band 4.1 like 2
Synonyms: D10Ertd398e, 4.1G, Epb4.1l2, NBL2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13822
VEGA: 10
HGNC: HGNC:3379
Homologene: 37478
Ucp2
Name: uncoupling protein 2 (mitochondrial, proton carrier)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22228
Homologene: 2516
Dscaml1
Name: DS cell adhesion molecule like 1
Synonyms: 4930435C18Rik, 4921507G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 114873
VEGA: 9
Homologene: 79549
Erbin
Name: Erbb2 interacting protein
Synonyms: Erbb2ip, 1700028E05Rik, Erbin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 59079
Homologene: 41282
Cenpc1
Name: centromere protein C1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12617
HGNC: HGNC:1854
Homologene: 1371
Cad
Name: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Synonyms: 2410008J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 69719
HGNC: HGNC:1424
Homologene: 1412
Sorbs1
Name: sorbin and SH3 domain containing 1
Synonyms: 9530001P15Rik, c-Cbl-associated protein, CAP, Sh3d5, Ponsin, 2310065E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 20411
VEGA: 19
Homologene: 83252
Spast
Name: spastin
Synonyms: Spg4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 50850
VEGA: 17
Homologene: 8970
Rsf1
Name: remodeling and spacing factor 1
Synonyms: XAP8, p325, 4832420A03Rik, C030033M12Rik, Hbxap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233532
Homologene: 41142
Prpf8
Name: pre-mRNA processing factor 8
Synonyms: Sfprp8l, Prp8, DBF3/PRP8, D11Bwg0410e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 192159
Homologene: 4706
Cc2d2a
Name: coiled-coil and C2 domain containing 2A
Synonyms: b2b1035Clo, 5730509K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231214
Homologene: 18159
Vars
Name: valyl-tRNA synthetase
Synonyms: G7a, Vars2, D17H6S56E, Bat6, Bat-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22321
Homologene: 4587
Pabpc1
Name: poly(A) binding protein, cytoplasmic 1
Synonyms: Pabpl1, Pabp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18458
HGNC: HGNC:8554
Homologene: 37638
Jph3
Name: junctophilin 3
Synonyms: JP-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 57340
Homologene: 10762
C3
Name: complement component 3
Synonyms: Plp, acylation stimulating protein, complement factor 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12266
HGNC: HGNC:1318
Homologene: 68031
Hrct1
Name: histidine rich carboxyl terminus 1
Synonyms: 3830408D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100039781
Cenpe
Name: centromere protein E
Synonyms: CENP-E, 312kDa, Kif10, N-7 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229841
HGNC: HGNC:1856
Homologene: 20429
Erc2
Name: ELKS/RAB6-interacting/CAST family member 2
Synonyms: ELKS2alpha, CAST, D14Ertd171e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 238988
Homologene: 69188
Eml2
Name: echinoderm microtubule associated protein like 2
Synonyms: 1600029N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72205
Homologene: 8125
Washc5
Name: WASH complex subunit 5
Synonyms: strumpellin, E430025E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223593
VEGA: 15
Homologene: 8898
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: Fam38b, Piezo2, 9030411M15Rik, Fam38b2, 9430028L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 667742
Homologene: 49695
Fsd1l
Name: fibronectin type III and SPRY domain containing 1-like
Synonyms: Ccdc10, Fsd1nl, Csdufd1, A230072O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 319636
Homologene: 45825
Magi2
Name: membrane associated guanylate kinase, WW and PDZ domain containing 2
Synonyms: S-SCAM, Acvrinp1, Magi-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 50791
Homologene: 8189
Polr2g
Name: polymerase (RNA) II (DNA directed) polypeptide G
Synonyms: A230108L04Rik, Rpo2-7l, 2410046K11Rik, RBP7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 67710
VEGA: 19
HGNC: HGNC:9194
Homologene: 2019
Pnldc1
Name: poly(A)-specific ribonuclease (PARN)-like domain containing 1
Synonyms: LOC240023
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 240023
VEGA: 17
Homologene: 15054
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC5, MUC9, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Ihh
Name: Indian hedgehog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16147
HGNC: HGNC:5956
Homologene: 22586
Aox1
Name: aldehyde oxidase 1
Synonyms: Aox2, Aox-2, retinal oxidase, Aox-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11761
HGNC: HGNC:553
Homologene: 68165
Tie1
Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Synonyms: TIE, tie-1, D430008P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 21846
Homologene: 3957
Tdrd1
Name: tudor domain containing 1
Synonyms: MTR-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 83561
Homologene: 12850
Adrb2
Name: adrenergic receptor, beta 2
Synonyms: beta 2-adrenoceptor, beta 2-AR, Gpcr7, Adrb-2, Badm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 11555
VEGA: 18
HGNC: HGNC:286
Homologene: 30948
Gm13089
Name: predicted gene 13089
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 277667
Cttnbp2
Name: cortactin binding protein 2
Synonyms: ORF4, 3010022N24Rik, Cortbp2, 9130022E09Rik, 4732477G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 30785
Homologene: 14125
Slc39a10
Name: solute carrier family 39 (zinc transporter), member 10
Synonyms: 2900042E17Rik, Zip10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227059
Homologene: 34076
Zfp963
Name: zinc finger protein 963
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 620419
Homologene: 49795
Fscn2
Name: fascin actin-bundling protein 2
Synonyms: ahl8, C630046B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 238021
HGNC: HGNC:3960
Homologene: 22722
Spata13
Name: spermatogenesis associated 13
Synonyms: ESTM11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219140
Homologene: 19482
Nipsnap1
Name: nipsnap homolog 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18082
HGNC: HGNC:7827
Homologene: 2695
Zfp647
Name: zinc finger protein 647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239546
VEGA: 15
Homologene: 27805
Zfp977
Name: zinc finger protein 977
Synonyms: Gm7221
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
Heatr3
Name: HEAT repeat containing 3
Synonyms: C030036P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234549
Homologene: 45429
Nemp1
Name: nuclear envelope integral membrane protein 1
Synonyms: Tmem194
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 210035
Homologene: 18346
Tmem59
Name: transmembrane protein 59
Synonyms: 3110046P06Rik, 1110001M20Rik, D4Ertd20e, MTDCF1, thymic dendritic cell-derived factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56374
HGNC: HGNC:1239
Homologene: 3583
Trim3
Name: tripartite motif-containing 3
Synonyms: HAC1, BERP1, Rnf22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 55992
Homologene: 21290
Vmn2r43
Name: vomeronasal 2, receptor 43
Synonyms: EC2-V2R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381838
Homologene: 113703
Rpl3l
Name: ribosomal protein L3-like
Synonyms: 1110057H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 66211
Homologene: 68434
Rfxap
Name: regulatory factor X-associated protein
Synonyms: 5730495K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 170767
HGNC: HGNC:9988
Homologene: 452
G6pc
Name: glucose-6-phosphatase, catalytic
Synonyms: Glc-6-Pase, Glc-6-Pase-alpha, G6Pase, G6pt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14377
HGNC: HGNC:4056
Homologene: 20079
Tmem255b
Name: transmembrane protein 255B
Synonyms: LOC272465, Fam70b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 272465
Homologene: 18804
Spata31d1a
Name: spermatogenesis associated 31 subfamily D, member 1A
Synonyms: 1700013B16Rik, Fam75d1a, Fam75d3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 72219
VEGA: 13
Homologene: 122131
4930539E08Rik
Name: RIKEN cDNA 4930539E08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 207819
Homologene: 52098
Gm43302
Name: predicted gene 43302
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 46,832,612 bp
  • T to C, chromosome 1 at 58,104,509 bp
  • T to C, chromosome 1 at 74,951,279 bp
  • T to C, chromosome 3 at 54,807,287 bp
  • T to C, chromosome 3 at 87,791,370 bp
  • T to A, chromosome 3 at 135,260,073 bp
  • T to C, chromosome 4 at 43,727,543 bp
  • A to G, chromosome 4 at 53,679,994 bp
  • T to A, chromosome 4 at 107,193,401 bp
  • A to G, chromosome 4 at 118,482,390 bp
  • T to C, chromosome 4 at 143,698,268 bp
  • G to A, chromosome 5 at 20,569,288 bp
  • A to G, chromosome 5 at 31,062,562 bp
  • C to T, chromosome 5 at 43,729,975 bp
  • A to G, chromosome 5 at 86,058,153 bp
  • A to G, chromosome 5 at 105,290,959 bp
  • A to G, chromosome 5 at 124,819,210 bp
  • A to G, chromosome 6 at 18,434,233 bp
  • T to C, chromosome 6 at 18,448,369 bp
  • T to C, chromosome 7 at 8,255,185 bp
  • G to A, chromosome 7 at 19,201,163 bp
  • A to G, chromosome 7 at 42,580,741 bp
  • GGCGGCGGC to GGCGGCGGCCGCGGCGGC, chromosome 7 at 97,579,906 bp
  • G to A, chromosome 7 at 100,498,131 bp
  • G to A, chromosome 7 at 105,617,539 bp
  • G to A, chromosome 7 at 141,849,060 bp
  • A to C, chromosome 7 at 141,858,288 bp
  • T to A, chromosome 8 at 13,456,958 bp
  • A to T, chromosome 8 at 69,743,203 bp
  • G to T, chromosome 8 at 88,138,140 bp
  • A to T, chromosome 8 at 121,753,552 bp
  • T to C, chromosome 9 at 32,317,800 bp
  • G to A, chromosome 9 at 45,450,583 bp
  • T to G, chromosome 10 at 25,501,832 bp
  • A to G, chromosome 10 at 127,689,243 bp
  • T to C, chromosome 11 at 4,888,895 bp
  • T to C, chromosome 11 at 75,494,022 bp
  • T to A, chromosome 11 at 101,367,976 bp
  • G to T, chromosome 11 at 120,361,787 bp
  • T to A, chromosome 13 at 59,702,994 bp
  • G to A, chromosome 13 at 103,844,921 bp
  • A to T, chromosome 14 at 28,011,636 bp
  • C to T, chromosome 14 at 60,750,021 bp
  • G to A, chromosome 15 at 25,736,642 bp
  • A to G, chromosome 15 at 36,600,651 bp
  • T to C, chromosome 15 at 59,335,170 bp
  • G to A, chromosome 15 at 76,912,085 bp
  • T to C, chromosome 17 at 12,890,363 bp
  • A to G, chromosome 17 at 24,730,887 bp
  • A to T, chromosome 17 at 28,904,623 bp
  • A to G, chromosome 17 at 35,001,529 bp
  • C to T, chromosome 17 at 57,206,223 bp
  • G to A, chromosome 17 at 74,373,305 bp
  • G to A, chromosome 18 at 60,811,486 bp
  • A to T, chromosome 18 at 62,179,466 bp
  • A to G, chromosome 18 at 63,012,645 bp
  • A to T, chromosome 19 at 8,797,309 bp
  • T to C, chromosome 19 at 40,314,657 bp
  • G to T, chromosome 19 at 56,843,223 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6073 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044234-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.