Strain Name:
C57BL/6J-MtgxR6089Btlr
Stock Number:
044246-MU
Citation ID:
RRID:MMRRC_044246-MU
Other Names:
R6089 (G1)
Major Collection:

Gene Information

Sall4
Name: spalt like transcription factor 4
Synonyms: Tex20, 5730441M18Rik, C330011P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99377
Homologene: 10716
Ptprf
Name: protein tyrosine phosphatase, receptor type, F
Synonyms: RPTP-LAR, LAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19268
HGNC: HGNC:9670
Homologene: 20623
Vps35l
Name: VPS35 endosomal protein sorting factor like
Synonyms: Vsp35l, 9030624J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71517
Homologene: 10659
Usp48
Name: ubiquitin specific peptidase 48
Synonyms: D330022K21Rik, Usp31, 2810449C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 170707
Homologene: 12988
Baz2a
Name: bromodomain adjacent to zinc finger domain, 2A
Synonyms: Walp3, C030005G16Rik, Tip5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 116848
VEGA: 10
HGNC: HGNC:962
Homologene: 8393
Helz
Name: helicase with zinc finger domain
Synonyms: 9630002H22Rik, 3110078M01Rik, 9430093I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 78455
Homologene: 8918
Zgrf1
Name: zinc finger, GRF-type containing 1
Synonyms: 4930422G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71643
Homologene: 34708
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: 2810449H11Rik, tbl, D130015N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Zfp26
Name: zinc finger protein 26
Synonyms: Zfp70, Zfp81-rs1, mkr-3, Zfp-26, 5033428C05Rik, KRAB15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22688
Homologene: 52318
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: E430018P19Rik, chromatin remodeling factor, KMT2H, 8030453L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 192195
Homologene: 10225
Tcf20
Name: transcription factor 20
Synonyms: 2810438H08Rik, SPBP, stromelysin 1 PDGF responsive element binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21411
VEGA: 15
Homologene: 4131
Hjurp
Name: Holliday junction recognition protein
Synonyms: 6430706D22Rik, A730008H23Rik, C330011F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381280
Homologene: 10184
Muc16
Name: mucin 16
Synonyms: Gm21044, LOC385009, 1110008I14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73732
Homologene: 141193
Gtpbp1
Name: GTP binding protein 1
Synonyms: GP-1, GTPBP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14904
VEGA: 15
HGNC: HGNC:4669
Homologene: 3165
Eif2ak3
Name: eukaryotic translation initiation factor 2 alpha kinase 3
Synonyms: PERK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13666
HGNC: HGNC:3255
Homologene: 3557
Ubr2
Name: ubiquitin protein ligase E3 component n-recognin 2
Synonyms: E130209G04Rik, 9930021A08Rik, ENSMUSG00000043296
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224826
VEGA: 17
Homologene: 26151
Poc5
Name: POC5 centriolar protein
Synonyms: 1200014M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67463
VEGA: 13
Homologene: 12141
Actr3
Name: ARP3 actin-related protein 3
Synonyms: Arp3, 1200003A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74117
HGNC: HGNC:170
Homologene: 68483
Pbrm1
Name: polybromo 1
Synonyms: 2310032M22Rik, 2610016F04Rik, Pb1, BAF180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66923
Homologene: 10044
Txndc5
Name: thioredoxin domain containing 5
Synonyms: PC-TRP, ERp46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105245
Homologene: 11125
Xxylt1
Name: xyloside xylosyltransferase 1
Synonyms: AI480653
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268880
Homologene: 17610
Grm2
Name: glutamate receptor, metabotropic 2
Synonyms: mGluR2, Gprc1b, 4930441L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 108068
HGNC: HGNC:4594
Homologene: 20229
A830010M20Rik
Name: RIKEN cDNA A830010M20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231570
VEGA: 5
Homologene: 128318
Tdo2
Name: tryptophan 2,3-dioxygenase
Synonyms: TO, chky, TDO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56720
Homologene: 4132
Cars2
Name: cysteinyl-tRNA synthetase 2 (mitochondrial)(putative)
Synonyms: 2410044A07Rik, 2310051N18Rik, D530030H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71941
Homologene: 11575
Cat
Name: catalase
Synonyms: Cas1, Cs-1, Cas-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12359
HGNC: HGNC:1516
Homologene: 55514
Myof
Name: myoferlin
Synonyms: Fer1l3, E030042N20Rik, 2310051D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226101
VEGA: 19
HGNC: HGNC:3656
Homologene: 40882
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Pigg
Name: phosphatidylinositol glycan anchor biosynthesis, class G
Synonyms: Gpi7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 433931
Homologene: 39421
Pcdhb10
Name: protocadherin beta 10
Synonyms: Pcdhb5D, PcdhbJ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93881
HGNC: HGNC:8690
Homologene: 88834
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: Gm980, A230079K17Rik, LOC381311, Dnahc14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Myh7b
Name: myosin, heavy chain 7B, cardiac muscle, beta
Synonyms: Myh14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668940
Homologene: 66117
Astn2
Name: astrotactin 2
Synonyms: Astnl, 1d8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56079
Homologene: 77850
Ifngr1
Name: interferon gamma receptor 1
Synonyms: Ifngr, IFN-gammaR, CD119, Nktar, Ifgr, IFN-gamma R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 15979
HGNC: HGNC:5439
Homologene: 359
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: IId, Myhsf2, Myhs-f, myosin heavy chain 2X, A530084A17Rik, IId/x, MYHC-IIX, MyHC-IId/x, Myhs-f2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Mre11a
Name: MRE11A homolog A, double strand break repair nuclease
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17535
HGNC: HGNC:7230
Homologene: 4083
Itgb7
Name: integrin beta 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16421
HGNC: HGNC:6162
Homologene: 20247
Vmn2r98
Name: vomeronasal 2, receptor 98
Synonyms: EG224552
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224552
Homologene: 115024
Dusp18
Name: dual specificity phosphatase 18
Synonyms: LMWDSP20, DSP18, DUSP20, 4930527G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75219
Homologene: 34984
Simc1
Name: SUMO-interacting motifs containing 1
Synonyms: 4732471D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319719
Homologene: 131217
Cers5
Name: ceramide synthase 5
Synonyms: CerS5, Lass5, 2310081H14Rik, Trh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71949
Homologene: 23634
Gabbr2
Name: gamma-aminobutyric acid (GABA) B receptor, 2
Synonyms: Gpr51, GB2, Gababr2, LOC242425
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242425
HGNC: HGNC:4507
Homologene: 55902
Scai
Name: suppressor of cancer cell invasion
Synonyms: A930041I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320271
Homologene: 15523
Ppp2r3a
Name: protein phosphatase 2, regulatory subunit B'', alpha
Synonyms: 3222402P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235542
HGNC: HGNC:9307
Homologene: 20595
Zkscan16
Name: zinc finger with KRAB and SCAN domains 16
Synonyms: Zfp483
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100041581
Homologene: 26419
Dzip1l
Name: DAZ interacting protein 1-like
Synonyms: 2610524A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72507
Homologene: 12466
Vill
Name: villin-like
Synonyms: Villp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22351
Homologene: 22650
Ptpru
Name: protein tyrosine phosphatase, receptor type, U
Synonyms: RPTPlambda, Ptprl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Cyp3a13
Name: cytochrome P450, family 3, subfamily a, polypeptide 13
Synonyms: IIIAm2, steroid inducible
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13113
HGNC: HGNC:2640
Homologene: 133564
Nacad
Name: NAC alpha domain containing
Synonyms: mKIAA0363
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192950
Homologene: 135717
Defb4
Name: defensin beta 4
Synonyms: MBD-4, 2310001F05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56519
Rtp3
Name: receptor transporter protein 3
Synonyms: Tmem7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235636
Homologene: 135957
Trdn
Name: triadin
Synonyms: triadin 3, triadin-1, triadin 2, triadin-3, triadin-2, EG432451, 2310045H21Rik, triadin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 76757
VEGA: 10
Homologene: 38137
Card10
Name: caspase recruitment domain family, member 10
Synonyms: CARMA3, Bimp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105844
Homologene: 8728
Zscan26
Name: zinc finger and SCAN domain containing 26
Synonyms: Zfp187
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 432731
Homologene: 43739
Calm4
Name: calmodulin 4
Synonyms: Scarf, 2310037J09Rik, DD112
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 80796
VEGA: 13
Homologene: 49485
Ankrd40
Name: ankyrin repeat domain 40
Synonyms: 1110011C06Rik, 5530600A18Rik, Gcap15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71452
Homologene: 12393
Vmn1r11
Name: vomeronasal 1 receptor 11
Synonyms: V1rc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113860
Homologene: 128345
Uqcrc2
Name: ubiquinol cytochrome c reductase core protein 2
Synonyms: 1500004O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67003
Homologene: 37764
Pcdha9
Name: protocadherin alpha 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 192161
HGNC: HGNC:8664
Homologene: 130700
Wfdc15a
Name: WAP four-disulfide core domain 15A
Synonyms: Wfdcl1, 1700049M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68221
Homologene: 77715
Dfna5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Gm15440
Name: predicted gene 15440
Synonyms: ENSMUSG00000051107
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • GT to GTT, chromosome 1 at 88,266,524 bp
  • A to G, chromosome 1 at 125,407,395 bp
  • G to T, chromosome 1 at 181,750,154 bp
  • A to T, chromosome 2 at 39,083,554 bp
  • C to A, chromosome 2 at 103,472,951 bp
  • A to T, chromosome 2 at 125,321,225 bp
  • C to T, chromosome 2 at 155,622,489 bp
  • A to T, chromosome 2 at 164,199,666 bp
  • T to C, chromosome 2 at 168,755,486 bp
  • T to C, chromosome 3 at 81,962,728 bp
  • C to T, chromosome 3 at 89,053,143 bp
  • G to A, chromosome 3 at 127,595,993 bp
  • A to G, chromosome 4 at 46,846,448 bp
  • A to G, chromosome 4 at 58,948,889 bp
  • A to G, chromosome 4 at 65,794,573 bp
  • A to G, chromosome 4 at 118,211,084 bp
  • G to C, chromosome 4 at 131,772,630 bp
  • T to C, chromosome 4 at 137,605,818 bp
  • C to T, chromosome 5 at 107,507,029 bp
  • A to T, chromosome 5 at 108,341,922 bp
  • T to A, chromosome 5 at 137,909,953 bp
  • A to G, chromosome 6 at 50,251,305 bp
  • T to C, chromosome 6 at 57,137,660 bp
  • A to T, chromosome 6 at 70,896,934 bp
  • T to G, chromosome 7 at 118,746,435 bp
  • A to T, chromosome 7 at 120,654,009 bp
  • A to G, chromosome 8 at 11,530,301 bp
  • A to T, chromosome 8 at 19,201,305 bp
  • G to A, chromosome 9 at 14,819,464 bp
  • A to G, chromosome 9 at 18,643,252 bp
  • G to T, chromosome 9 at 20,437,693 bp
  • A to C, chromosome 9 at 66,445,532 bp
  • C to A, chromosome 9 at 99,642,684 bp
  • T to A, chromosome 9 at 101,211,636 bp
  • G to A, chromosome 9 at 106,653,891 bp
  • T to C, chromosome 9 at 110,986,973 bp
  • A to G, chromosome 9 at 119,057,799 bp
  • T to C, chromosome 10 at 19,606,300 bp
  • C to T, chromosome 10 at 33,464,575 bp
  • TCTCCTC to TCTC, chromosome 10 at 128,114,642 bp
  • A to G, chromosome 11 at 3,897,555 bp
  • A to G, chromosome 11 at 6,601,331 bp
  • T to A, chromosome 11 at 67,202,167 bp
  • T to G, chromosome 11 at 67,220,787 bp
  • A to T, chromosome 11 at 94,333,925 bp
  • A to T, chromosome 11 at 107,595,137 bp
  • A to G, chromosome 11 at 119,416,559 bp
  • A to T, chromosome 13 at 3,837,874 bp
  • G to T, chromosome 13 at 21,448,329 bp
  • A to T, chromosome 13 at 38,523,416 bp
  • A to T, chromosome 13 at 51,691,401 bp
  • G to A, chromosome 13 at 54,528,490 bp
  • G to T, chromosome 13 at 96,396,671 bp
  • T to C, chromosome 14 at 31,087,585 bp
  • T to C, chromosome 15 at 78,802,414 bp
  • A to G, chromosome 15 at 79,706,997 bp
  • G to T, chromosome 15 at 82,853,208 bp
  • G to T, chromosome 15 at 99,741,002 bp
  • T to C, chromosome 15 at 102,217,286 bp
  • C to T, chromosome 16 at 31,080,981 bp
  • A to G, chromosome 17 at 19,066,074 bp
  • A to C, chromosome 17 at 46,982,292 bp
  • T to C, chromosome 18 at 36,998,498 bp
  • T to C, chromosome 18 at 37,413,626 bp
  • T to C, chromosome 19 at 37,967,060 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6089 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044246-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.