Strain Name:
C57BL/6J-MtgxR6113Btlr
Stock Number:
044262-MU
Citation ID:
RRID:MMRRC_044262-MU
Other Names:
R6113 (G1)
Major Collection:

Gene Information

Tle4
Name: transducin-like enhancer of split 4
Synonyms: Grg4, ESTM13, ESTM14, Bce1, 5730411M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 21888
VEGA: 19
Homologene: 38259
Vcan
Name: versican
Synonyms: PG-M, hdf, heart defect, 5430420N07Rik, Cspg2, DPEAAE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
Pcdh9
Name: protocadherin 9
Synonyms: C630029H24Rik, 1500001L12Rik, LOC382930, A730003J17Rik, C530050I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 211712
HGNC: HGNC:8661
Homologene: 10698
Slc17a7
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
Synonyms: Vglut1, 2900052E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72961
Homologene: 113454
Cr1l
Name: complement component (3b/4b) receptor 1-like
Synonyms: mCRY, Crry
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12946
Homologene: 128275
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: Megalin, Gp330, D230004K18Rik, b2b1625.2Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Dclre1c
Name: DNA cross-link repair 1C
Synonyms: 9930121L06Rik, Artemis, Art
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227525
Homologene: 32547
Srgap2
Name: SLIT-ROBO Rho GTPase activating protein 2
Synonyms: FBP2, 9930124L22Rik, Fnbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14270
Homologene: 52683
Rgs12
Name: regulator of G-protein signaling 12
Synonyms: 4632412M04Rik, 1200016K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71729
HGNC: HGNC:9994
Homologene: 2195
Dnm1l
Name: dynamin 1-like
Synonyms: 6330417M19Rik, Drp1, python, Dnmlp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74006
VEGA: 16
HGNC: HGNC:2973
Homologene: 6384
Zfhx3
Name: zinc finger homeobox 3
Synonyms: WBP9, A230102L03Rik, Atbf1, Sci
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Fkbp15
Name: FK506 binding protein 15
Synonyms: FKBP133, C430014M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 338355
Homologene: 28743
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: MAP1C, dynein heavy chain, retrograde transport, Dnec1, Loa, 9930018I23Rik, Dnchc1, Swl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Pold1
Name: polymerase (DNA directed), delta 1, catalytic subunit
Synonyms: 125kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18971
HGNC: HGNC:9175
Homologene: 2014
Utp25
Name: UTP25 small subunit processome component
Synonyms: AA408296, Diexf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 215193
Homologene: 6170
Dsp
Name: desmoplakin
Synonyms: DP, 2300002E22Rik, 5730453H04Rik, rul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Fgf23
Name: fibroblast growth factor 23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 64654
HGNC: HGNC:3680
Homologene: 10771
Cplx3
Name: complexin 3
Synonyms: CpxIII, Lman1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235415
VEGA: 9
Homologene: 77368
Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Synonyms: cytochrome P450 subfamily I, polypeptide 1, P450-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13076
VEGA: 9
HGNC: HGNC:2595
Homologene: 68062
Eml5
Name: echinoderm microtubule associated protein like 5
Synonyms: C130068M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319670
VEGA: 12
Homologene: 26807
Nbeal1
Name: neurobeachin like 1
Synonyms: A530050O19Rik, ALS2CR17, A530083I02Rik, 2310076G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269198
Homologene: 16453
Rec8
Name: REC8 meiotic recombination protein
Synonyms: mrec, Rec8L1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56739
Homologene: 3768
Srcap
Name: Snf2-related CREBBP activator protein
Synonyms: F630004O05Rik, B930091H02Rik, D030022P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043597
Homologene: 38213
Wdr72
Name: WD repeat domain 72
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 546144
Homologene: 52326
Vav1
Name: vav 1 oncogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22324
Homologene: 3961
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Naip6
Name: NLR family, apoptosis inhibitory protein 6
Synonyms: Naip-rs4A, Naip-rs4, Birc1f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17952
HGNC: HGNC:7634
Homologene: 113589
Dclk1
Name: doublecortin-like kinase 1
Synonyms: CPG16, DCLK, 1700113D08Rik, 2810480F11Rik, Dcl, Click-I, Dcamkl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 13175
HGNC: HGNC:2700
Homologene: 130530
Sfmbt1
Name: Scm-like with four mbt domains 1
Synonyms: Smr, 4930442N21Rik, 9330180L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 54650
Homologene: 9472
Ly75
Name: lymphocyte antigen 75
Synonyms: DEC-205, CD205
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17076
Homologene: 31085
Usp35
Name: ubiquitin specific peptidase 35
Synonyms: LOC244144, LOC381901
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244144
Homologene: 35459
Chtf18
Name: CTF18, chromosome transmission fidelity factor 18
Synonyms: 6030457M03Rik, CTF18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 214901
Homologene: 32532
Dcst2
Name: DC-STAMP domain containing 2
Synonyms: LOC329702
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329702
Homologene: 16951
Morc2b
Name: microrchidia 2B
Synonyms: 4932411A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240069
Homologene: 18615
Vmn2r5
Name: vomeronasal 2, receptor 5
Synonyms: EG667060
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 667060
Trpv3
Name: transient receptor potential cation channel, subfamily V, member 3
Synonyms: 1110036I10Rik, VRL3, Nh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246788
Homologene: 17040
Pkp3
Name: plakophilin 3
Synonyms: 2310056L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56460
HGNC: HGNC:9025
Homologene: 5200
Bpifb6
Name: BPI fold containing family B, member 6
Synonyms: LOC228796, Bpil3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228796
Homologene: 18375
Rad21l
Name: RAD21-like (S. pombe)
Synonyms: Gm14160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668929
Homologene: 82650
Rab13
Name: RAB13, member RAS oncogene family
Synonyms: B230212B15Rik, 0610007N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68328
HGNC: HGNC:9762
Homologene: 113882
Aldh1l2
Name: aldehyde dehydrogenase 1 family, member L2
Synonyms: D330038I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216188
Homologene: 51942
Tnfrsf14
Name: tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
Synonyms: HveA, Atar, Hvem
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230979
Homologene: 2833
Myo18b
Name: myosin XVIIIb
Synonyms: 4932408L24Rik, 4933411E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74376
Homologene: 53435
Vmn1r25
Name: vomeronasal 1 receptor 25
Synonyms: V1rc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113865
Homologene: 137652
Cilp2
Name: cartilage intermediate layer protein 2
Synonyms: CLIP-2, 1110031K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 68709
Homologene: 17713
P3h2
Name: prolyl 3-hydroxylase 2
Synonyms: Leprel1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 210530
Homologene: 10062
Gm12185
Name: predicted gene 12185
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 620913
Homologene: 83188
Tyk2
Name: tyrosine kinase 2
Synonyms: JTK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 54721
VEGA: 9
Homologene: 20712
Atpsckmt
Name: ATP synthase C subunit lysine N-methyltransferase
Synonyms: A930016P21Rik, Fam173b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68073
Homologene: 16780
Dnd1
Name: DND microRNA-mediated repression inhibitor 1
Synonyms: RBMS4, Ter
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 213236
Homologene: 65262
Tenm1
Name: teneurin transmembrane protein 1
Synonyms: Ten-m1, TCAP-1, teneurin-1, Odz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 23963
HGNC: HGNC:8117
Homologene: 56542
Lrrc69
Name: leucine rich repeat containing 69
Synonyms: 1700034K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 73314
Homologene: 78018
Thpo
Name: thrombopoietin
Synonyms: Mpllg, TPO-4, TPO-3, TPO-2, TPO-1, TPO, myeloproliferative leukemia virus oncogene ligand
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 21832
Homologene: 398
Prdm6
Name: PR domain containing 6
Synonyms: LOC225518, PRISM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225518
HGNC: HGNC:9350
Homologene: 79756
Trib1
Name: tribbles pseudokinase 1
Synonyms: A530090O15Rik, Trb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 211770
Homologene: 75216
Fgf6
Name: fibroblast growth factor 6
Synonyms: Fgf-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14177
HGNC: HGNC:3684
Homologene: 10870
Abat
Name: 4-aminobutyrate aminotransferase
Synonyms: 9630038C02Rik, GABA-T
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268860
HGNC: HGNC:23
Homologene: 542
Trbv13-1
Name: T cell receptor beta, variable 13-1
Synonyms: Tcrb-V8.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100124673
Trav15-2-dv6-2
Name: T cell receptor alpha variable 15-2-DV6-2
Synonyms: Trav15-2/dv6-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 436545
Gm20647
Name: predicted gene 20647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 60,222,263 bp
  • A to T, chromosome 1 at 131,355,505 bp
  • T to C, chromosome 1 at 193,129,502 bp
  • T to C, chromosome 1 at 195,131,411 bp
  • T to C, chromosome 2 at 3,452,863 bp
  • T to G, chromosome 2 at 60,368,873 bp
  • G to C, chromosome 2 at 69,483,557 bp
  • A to C, chromosome 2 at 151,657,478 bp
  • G to A, chromosome 2 at 153,910,731 bp
  • T to C, chromosome 3 at 55,489,819 bp
  • T to C, chromosome 3 at 64,491,399 bp
  • T to C, chromosome 3 at 89,367,885 bp
  • C to A, chromosome 3 at 90,224,866 bp
  • T to C, chromosome 4 at 14,708,673 bp
  • G to A, chromosome 4 at 62,340,647 bp
  • T to C, chromosome 4 at 154,924,492 bp
  • C to A, chromosome 5 at 35,020,323 bp
  • A to G, chromosome 5 at 72,329,800 bp
  • C to G, chromosome 5 at 112,866,385 bp
  • C to T, chromosome 6 at 41,116,379 bp
  • T to C, chromosome 6 at 57,978,572 bp
  • T to C, chromosome 6 at 127,015,937 bp
  • A to G, chromosome 6 at 127,078,154 bp
  • C to A, chromosome 7 at 44,537,700 bp
  • A to G, chromosome 7 at 45,174,751 bp
  • A to G, chromosome 7 at 97,324,326 bp
  • C to A, chromosome 7 at 127,560,281 bp
  • T to A, chromosome 7 at 141,082,656 bp
  • T to C, chromosome 8 at 69,882,359 bp
  • T to A, chromosome 8 at 108,947,421 bp
  • A to T, chromosome 9 at 21,107,922 bp
  • T to A, chromosome 9 at 57,602,440 bp
  • T to A, chromosome 9 at 57,701,891 bp
  • T to A, chromosome 9 at 74,152,641 bp
  • G to T, chromosome 10 at 83,508,134 bp
  • A to T, chromosome 11 at 48,915,340 bp
  • G to A, chromosome 11 at 73,286,018 bp
  • A to G, chromosome 11 at 118,126,275 bp
  • T to A, chromosome 12 at 98,824,674 bp
  • T to C, chromosome 12 at 110,620,414 bp
  • T to A, chromosome 13 at 38,192,047 bp
  • T to A, chromosome 13 at 89,657,536 bp
  • T to C, chromosome 13 at 100,299,286 bp
  • A to G, chromosome 14 at 30,815,184 bp
  • T to G, chromosome 14 at 53,649,725 bp
  • G to A, chromosome 14 at 55,622,478 bp
  • A to G, chromosome 14 at 93,887,108 bp
  • T to C, chromosome 15 at 31,608,162 bp
  • C to T, chromosome 15 at 59,651,638 bp
  • C to A, chromosome 16 at 8,572,900 bp
  • T to C, chromosome 16 at 16,341,003 bp
  • C to A, chromosome 16 at 20,728,847 bp
  • A to T, chromosome 16 at 25,981,153 bp
  • G to A, chromosome 17 at 25,722,867 bp
  • G to T, chromosome 17 at 33,138,068 bp
  • T to A, chromosome 17 at 57,301,884 bp
  • T to A, chromosome 18 at 36,765,395 bp
  • T to A, chromosome 18 at 53,473,601 bp
  • A to T, chromosome 19 at 14,595,588 bp
  • C to T, chromosome X at 42,827,195 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6113 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044262-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.