Strain Name:
C57BL/6J-MtgxR6115Btlr
Stock Number:
044264-MU
Citation ID:
RRID:MMRRC_044264-MU
Other Names:
R6115 (G1)
Major Collection:

Gene Information

Magi1
Name: membrane associated guanylate kinase, WW and PDZ domain containing 1
Synonyms: BAP1, Gukmi1, WWP3, Baiap1, AIP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14924
HGNC: HGNC:946
Homologene: 31257
Tm9sf4
Name: transmembrane 9 superfamily protein member 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99237
Homologene: 21620
Sfpq
Name: splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
Synonyms: 9030402K04Rik, 5730453G22Rik, 1110004P21Rik, D4Ertd314e, 2810416M14Rik, PSF, REP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 71514
Homologene: 3714
Nsmce4a
Name: NSE4 homolog A, SMC5-SMC6 complex component
Synonyms: 2410003A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67872
Homologene: 9745
Prpf31
Name: pre-mRNA processing factor 31
Synonyms: 1500019O16Rik, 2810404O06Rik, RP11, PRP31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68988
Homologene: 5980
Unc5b
Name: unc-5 netrin receptor B
Synonyms: Unc5h2, 6330415E02Rik, D10Bwg0792e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 107449
VEGA: 10
Homologene: 32538
Lrfn4
Name: leucine rich repeat and fibronectin type III domain containing 4
Synonyms: SALM3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225875
Homologene: 36415
Fam3b
Name: family with sequence similarity 3, member B
Synonyms: 9030624C24Rik, ORF9, D16Jhu19e, Pander
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 52793
HGNC: HGNC:1253
Homologene: 10766
Kif13a
Name: kinesin family member 13A
Synonyms: 4930505I07Rik, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 16553
VEGA: 13
Homologene: 22589
Hmg20a
Name: high mobility group 20A
Synonyms: Hmgxb1, 5730490E10Rik, 1200004E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 66867
VEGA: 9
HGNC: HGNC:5001
Homologene: 32399
Dhx29
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 29
Synonyms: E130202M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218629
VEGA: 13
Homologene: 10387
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225115
Homologene: 25090
Mthfsl
Name: 5, 10-methenyltetrahydrofolate synthetase-like
Synonyms: Gm2382
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 100039707
HGNC: HGNC:7437
Homologene: 4702
Fign
Name: fidgetin
Synonyms: Fgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 60344
Homologene: 5813
Il16
Name: interleukin 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16170
HGNC: HGNC:5980
Homologene: 18157
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 77505
Homologene: 131117
F7
Name: coagulation factor VII
Synonyms: FVII, Cf7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14068
HGNC: HGNC:3544
Homologene: 7710
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: 2900022L05Rik, Dnahc2, D330014H01Rik, Dnhd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Slc9c1
Name: solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
Synonyms: LOC208169, spermNHE, Slc9a10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 208169
Homologene: 19505
Hc
Name: hemolytic complement
Synonyms: C5, C5a, Hfib2, He
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Scn9a
Name: sodium channel, voltage-gated, type IX, alpha
Synonyms: PN1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20274
Homologene: 2237
Sycp2
Name: synaptonemal complex protein 2
Synonyms: 4930518F03Rik, 3830402K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 320558
Homologene: 8604
Arhgef38
Name: Rho guanine nucleotide exchange factor (GEF) 38
Synonyms: 9130221D24Rik, D630013G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77669
Homologene: 137396
Olfr1281
Name: olfactory receptor 1281
Synonyms: MOR248-14P, MOR248-18, GA_x6K02T2Q125-72379864-72380781
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 257979
HGNC: null
Homologene: 73992
Adam34
Name: a disintegrin and metallopeptidase domain 34
Synonyms: testase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 252866
HGNC: null
Homologene: 78104
Vmn2r85
Name: vomeronasal 2, receptor 85
Synonyms: EG623734
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 623734
HGNC: null
Homologene: 129606
Corin
Name: corin, serine peptidase
Synonyms: Lrp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 53419
Homologene: 4804
Olfr344
Name: olfactory receptor 344
Synonyms: GA_x6K02T2NLDC-33262744-33263673, MOR136-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258621
HGNC: null
Homologene: null
Vmn2r18
Name: vomeronasal 2, receptor 18
Synonyms: EG632671
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 632671
HGNC: null
Homologene: null
Zbtb4
Name: zinc finger and BTB domain containing 4
Synonyms: 9230111I22Rik, 2310026P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75580
Homologene: 10846
Zfp110
Name: zinc finger protein 110
Synonyms: NRIF, 2900024E01Rik, Nrif1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 65020
Homologene: 129707
Tmc3
Name: transmembrane channel-like gene family 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233424
Homologene: 45588
Lrrc49
Name: leucine rich repeat containing 49
Synonyms: D430025H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102747
Homologene: 9782
Tmem163
Name: transmembrane protein 163
Synonyms: beta-actin-Cre, SV31, 2610024A01Rik, beta-actin:Cre, beta-actin-cre, Tg(ACTB-cre)2Mrt, creactin, actin-cre, TgN(ACTB-cre)2Mrt, beta-actin::Cre, Act-Cre, A-cre
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 72160
Homologene: 12798
Herc6
Name: hect domain and RLD 6
Synonyms: CEB1, 4930427L17Rik, Herc5, 1700121D12Rik, 2510038N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67138
Homologene: 70768
Acsf3
Name: acyl-CoA synthetase family member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 257633
Homologene: 14958
0610040J01Rik
Name: RIKEN cDNA 0610040J01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 76261
Homologene: 49537
Olfr1449
Name: olfactory receptor 1449
Synonyms: GA_x6K02T2RE5P-3264213-3265157, MOR202-34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258300
HGNC: null
Homologene: 17184
Ctnna2
Name: catenin (cadherin associated protein), alpha 2
Synonyms: Catna, Catna2, alpha(N)-catenin, alpha N-catenin, chp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12386
HGNC: HGNC:2510
Homologene: 68394
Qrfpr
Name: pyroglutamylated RFamide peptide receptor
Synonyms: Gpr103, AQ27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229214
Homologene: 18865
Rnf170
Name: ring finger protein 170
Synonyms: 6720407G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 77733
Homologene: 12807
Vmn2r106
Name: vomeronasal 2, receptor 106
Synonyms: EG224576
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224576
HGNC: null
Homologene: 135824
Ccdc102a
Name: coiled-coil domain containing 102A
Synonyms: LOC234582
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234582
Homologene: 13240
Lactb
Name: lactamase, beta
Synonyms: Mrpl56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 80907
VEGA: 9
Homologene: 12755
Stk32c
Name: serine/threonine kinase 32C
Synonyms: Pkek, YANK3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 57740
Homologene: 75157
Olfr1299
Name: olfactory receptor 1299
Synonyms: MOR248-8, GA_x6K02T2Q125-72715642-72716580
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258886
HGNC: null
Homologene: 17426
Yod1
Name: YOD1 deubiquitinase
Synonyms: 9930028C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226418
Homologene: 13176
Alx1
Name: ALX homeobox 1
Synonyms: Cart1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216285
HGNC: HGNC:1494
Homologene: 5075
Lmx1b
Name: LIM homeobox transcription factor 1 beta
Synonyms: LMX1.2, GENA 191, Icst
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16917
HGNC: HGNC:6654
Homologene: 55648
Pcdha7
Name: protocadherin alpha 7
Synonyms: Cnr4, Crnr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 12939
HGNC: HGNC:8673
Homologene: 117962
Pcdhga8
Name: protocadherin gamma subfamily A, 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93716
HGNC: HGNC:8706
Homologene: 57162
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 127,677,448 bp
  • T to C, chromosome 1 at 130,719,063 bp
  • T to C, chromosome 2 at 33,569,106 bp
  • T to G, chromosome 2 at 35,013,038 bp
  • A to T, chromosome 2 at 36,568,951 bp
  • T to C, chromosome 2 at 63,979,310 bp
  • T to A, chromosome 2 at 66,563,629 bp
  • A to G, chromosome 2 at 111,329,213 bp
  • A to T, chromosome 2 at 111,664,642 bp
  • T to C, chromosome 2 at 153,182,489 bp
  • G to C, chromosome 2 at 178,348,245 bp
  • C to T, chromosome 3 at 36,182,593 bp
  • A to T, chromosome 3 at 133,132,613 bp
  • A to T, chromosome 4 at 127,021,348 bp
  • C to G, chromosome 5 at 63,897,974 bp
  • T to A, chromosome 5 at 72,360,729 bp
  • A to T, chromosome 5 at 151,584,997 bp
  • A to G, chromosome 6 at 57,583,206 bp
  • A to G, chromosome 6 at 77,636,839 bp
  • A to C, chromosome 6 at 93,708,070 bp
  • T to C, chromosome 7 at 3,639,706 bp
  • A to T, chromosome 7 at 12,849,774 bp
  • A to T, chromosome 7 at 83,614,962 bp
  • G to A, chromosome 7 at 83,652,567 bp
  • A to G, chromosome 7 at 105,713,987 bp
  • G to T, chromosome 7 at 130,546,992 bp
  • G to T, chromosome 7 at 139,120,712 bp
  • T to A, chromosome 8 at 13,033,958 bp
  • T to C, chromosome 8 at 26,125,966 bp
  • T to G, chromosome 8 at 43,652,061 bp
  • T to C, chromosome 8 at 94,903,371 bp
  • T to A, chromosome 8 at 122,790,672 bp
  • A to T, chromosome 9 at 56,489,832 bp
  • A to T, chromosome 9 at 60,615,161 bp
  • G to T, chromosome 9 at 66,967,687 bp
  • T to A, chromosome 9 at 88,688,754 bp
  • C to A, chromosome 10 at 60,777,546 bp
  • G to A, chromosome 10 at 103,028,443 bp
  • T to G, chromosome 10 at 130,422,803 bp
  • C to A, chromosome 11 at 69,446,649 bp
  • T to C, chromosome 11 at 69,776,322 bp
  • T to A, chromosome 13 at 46,801,313 bp
  • A to T, chromosome 13 at 112,952,801 bp
  • A to T, chromosome 16 at 45,555,769 bp
  • T to G, chromosome 16 at 97,475,368 bp
  • G to A, chromosome 17 at 20,268,376 bp
  • A to G, chromosome 18 at 5,108,675 bp
  • A to G, chromosome 18 at 36,974,735 bp
  • T to A, chromosome 18 at 37,727,543 bp
  • T to C, chromosome 19 at 4,613,909 bp
  • T to C, chromosome 19 at 12,935,584 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6115 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044264-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.