Strain Name:
C57BL/6J-MtgxR6129Btlr
Stock Number:
044276-MU
Citation ID:
RRID:MMRRC_044276-MU
Other Names:
R6129 (G1)
Major Collection:

Gene Information

Sptbn4
Name: spectrin beta, non-erythrocytic 4
Synonyms: 1700022P15Rik, 5830426A08Rik, neuroaxonal dystrophy, dyn, Spnb4, nmf261, ROSA62, SpbIV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 80297
Homologene: 11879
Hps5
Name: HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
Synonyms: Hermansky-Pudlak syndrome 5, ru-2, ruby eye 2, ru2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 246694
Homologene: 35333
Bcl2l2
Name: BCL2-like 2
Synonyms: Gtrosa41, Bcl-w, bclw, Gtrgal2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12050
HGNC: HGNC:995
Homologene: 2989
Lrrn3
Name: leucine rich repeat protein 3, neuronal
Synonyms: NLRR-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 16981
VEGA: 12
Homologene: 36315
Ctnnal1
Name: catenin (cadherin associated protein), alpha-like 1
Synonyms: ACRP, Catnal1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 54366
HGNC: HGNC:2512
Homologene: 2815
Ccn1
Name: cellular communication network factor 1
Synonyms: Cyr61, CCN1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 16007
HGNC: HGNC:2654
Homologene: 1194
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77595
Homologene: 28122
Plxnd1
Name: plexin D1
Synonyms: 6230425C21Rik, b2b1863Clo, b2b553Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67784
HGNC: HGNC:9107
Homologene: 22866
Mysm1
Name: myb-like, SWIRM and MPN domains 1
Synonyms: C130067A03Rik, C530050H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 320713
Homologene: 66204
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: C130061D10Rik, Pam, Phr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105689
Homologene: 9005
Pcbp3
Name: poly(rC) binding protein 3
Synonyms: AlphaCP-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 59093
HGNC: HGNC:8651
Homologene: 23233
Sap130
Name: Sin3A associated protein
Synonyms: 2610304F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 269003
VEGA: 18
Homologene: 11577
Adgrl1
Name: adhesion G protein-coupled receptor L1
Synonyms: lectomedin-2, Lec2, Lphn1, 2900070I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 330814
Homologene: 8951
Robo1
Name: roundabout guidance receptor 1
Synonyms: DUTT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19876
Homologene: 2206
Robo3
Name: roundabout guidance receptor 3
Synonyms: Rig1, Rbig1, Rig-1, Robo3a, Robo3b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19649
Homologene: 32119
Brms1l
Name: breast cancer metastasis-suppressor 1-like
Synonyms: 0710008O11Rik, BRMS1, D12Ertd407e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 52592
VEGA: 12
Homologene: 9123
Crim1
Name: cysteine rich transmembrane BMP regulator 1 (chordin like)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 50766
VEGA: 17
HGNC: HGNC:2359
Homologene: 9510
Rsrc1
Name: arginine/serine-rich coiled-coil 1
Synonyms: SRrp53, 1200013F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66880
Homologene: 41147
Eml2
Name: echinoderm microtubule associated protein like 2
Synonyms: 1600029N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72205
Homologene: 8125
Rufy1
Name: RUN and FYVE domain containing 1
Synonyms: 3000002E04Rik, ZFYVE12, Rabip4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216724
Homologene: 23522
Pcdh12
Name: protocadherin 12
Synonyms: vascular endothelial cadherin-2, VE-cadherin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 53601
HGNC: HGNC:8657
Homologene: 9574
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171395
Homologene: 51376
Ppp1r12b
Name: protein phosphatase 1, regulatory subunit 12B
Synonyms: 1810037O03Rik, 9530009M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329251
HGNC: HGNC:7619
Homologene: 135710
Clec4b1
Name: C-type lectin domain family 4, member b1
Synonyms: mDcar2, 1810046I24Rik, DCARbeta, 1810046I24Rik, DCAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 69810
Homologene: 130350
Peg10
Name: paternally expressed 10
Synonyms: Mar2, Rtl2, HB-1, MEF3L, Mart2, MyEF-3, MyEF-3 like, Edr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 170676
Homologene: 116067
Tex15
Name: testis expressed gene 15
Synonyms: 2210014E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 104271
Homologene: 12837
BC067074
Name: cDNA sequence BC067074
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 408066
Rusc2
Name: RUN and SH3 domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100213
Homologene: 18967
Stk10
Name: serine/threonine kinase 10
Synonyms: Lok, Gek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20868
Homologene: 38122
Phf7
Name: PHD finger protein 7
Synonyms: 1700006H01Rik, 1700010P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71838
VEGA: 14
Homologene: 69217
Gm5114
Name: predicted gene 5114
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330513
Homologene: 45597
Ermp1
Name: endoplasmic reticulum metallopeptidase 1
Synonyms: b2b2633Clo, D19Ertd410e, D19Wsu12e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226090
Homologene: 121891
Jag2
Name: jagged 2
Synonyms: Serh, D12Ggc2e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 16450
VEGA: 12
HGNC: HGNC:6189
Homologene: 1677
Aatk
Name: apoptosis-associated tyrosine kinase
Synonyms: AATYK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11302
HGNC: HGNC:21
Homologene: 74861
Cyp27a1
Name: cytochrome P450, family 27, subfamily a, polypeptide 1
Synonyms: cholesterol 27 hydroxylase, 1300013A03Rik, Cyp27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 104086
HGNC: HGNC:2605
Homologene: 36040
Pappa2
Name: pappalysin 2
Synonyms: PAPP-A2, placenta-specific 3, pregnancy-associated plasma preproprotein-A2, pregnancy-associated plasma protein-E, PLAC3, Pappe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 23850
Homologene: 10661
Csmd2
Name: CUB and Sushi multiple domains 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329942
Homologene: 89034
Me1
Name: malic enzyme 1, NADP(+)-dependent, cytosolic
Synonyms: Mod-1, Mdh-1, Mod1, D9Ertd267e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17436
HGNC: HGNC:6983
Homologene: 134785
Ankrd34a
Name: ankyrin repeat domain 34A
Synonyms: Ankrd34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 545554
Homologene: 82882
Dsc2
Name: desmocollin 2
Synonyms: Dsc2a, Dsc2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13506
HGNC: HGNC:3036
Homologene: 8397
Hdac9
Name: histone deacetylase 9
Synonyms: Hdac7b, D030072B18Rik, HDRP, Mitr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 79221
Homologene: 128578
Pde8b
Name: phosphodiesterase 8B
Synonyms: B230331L10Rik, C030047E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218461
HGNC: HGNC:8794
Homologene: 2758
Gm10549
Name: predicted gene 10549
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 433171
VEGA: 18
Prps1l1
Name: phosphoribosyl pyrophosphate synthetase 1-like 1
Synonyms: 1700011K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75456
HGNC: HGNC:9463
Homologene: 75282
Acsm2
Name: acyl-CoA synthetase medium-chain family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233799
Homologene: 70404
Zfp647
Name: zinc finger protein 647
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239546
VEGA: 15
Homologene: 27805
Fbxo6
Name: F-box protein 6
Synonyms: Fbx6b, Fbs2, FBG2, Fbxo6b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 50762
Homologene: 9274
Hao2
Name: hydroxyacid oxidase 2
Synonyms: Hao3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56185
HGNC: HGNC:4810
Homologene: 97412
Zscan4b
Name: zinc finger and SCAN domain containing 4B
Synonyms: EG665780
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 665780
Homologene: 85986
Mkx
Name: mohawk homeobox
Synonyms: Irxl1, 9430023B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 210719
Homologene: 72239
Gm5431
Name: predicted gene 5431
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432555
2810408A11Rik
Name: RIKEN cDNA 2810408A11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70419
Homologene: 49883
Pcna-ps2
Name: proliferating cell nuclear antigen pseudogene 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18540
VEGA: 19
Tnxa
Name: tenascin XA (pseudogene)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100043024
Dnase1l1
Name: deoxyribonuclease 1-like 1
Synonyms: 2310005K03Rik, Dnase1ll, G4.8, Dnl1ll
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 69537
HGNC: HGNC:2957
Homologene: 4896
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 74,735,692 bp
  • C to T, chromosome 1 at 134,892,252 bp
  • A to T, chromosome 1 at 158,714,997 bp
  • C to T, chromosome 3 at 66,994,649 bp
  • T to C, chromosome 3 at 90,104,176 bp
  • T to A, chromosome 3 at 96,597,958 bp
  • T to C, chromosome 3 at 98,880,526 bp
  • T to C, chromosome 3 at 145,649,231 bp
  • T to C, chromosome 4 at 43,424,271 bp
  • C to A, chromosome 4 at 56,829,573 bp
  • C to A, chromosome 4 at 94,967,955 bp
  • G to A, chromosome 4 at 128,493,334 bp
  • A to T, chromosome 4 at 148,149,522 bp
  • GAT to GATCAT, chromosome 6 at 4,756,449 bp
  • A to G, chromosome 6 at 115,978,174 bp
  • A to G, chromosome 6 at 123,068,502 bp
  • T to A, chromosome 7 at 10,901,888 bp
  • G to A, chromosome 7 at 19,201,163 bp
  • C to A, chromosome 7 at 27,360,088 bp
  • C to T, chromosome 7 at 39,408,600 bp
  • A to G, chromosome 7 at 46,771,774 bp
  • G to A, chromosome 7 at 119,591,247 bp
  • A to T, chromosome 8 at 33,574,130 bp
  • A to G, chromosome 8 at 83,918,987 bp
  • A to G, chromosome 9 at 37,423,293 bp
  • A to T, chromosome 9 at 86,650,956 bp
  • T to C, chromosome 10 at 76,763,348 bp
  • A to G, chromosome 11 at 8,868,543 bp
  • T to A, chromosome 11 at 32,615,871 bp
  • A to G, chromosome 11 at 48,889,591 bp
  • A to T, chromosome 11 at 50,417,248 bp
  • T to A, chromosome 11 at 69,898,311 bp
  • C to T, chromosome 11 at 120,021,533 bp
  • A to C, chromosome 12 at 34,287,475 bp
  • A to G, chromosome 12 at 34,985,330 bp
  • G to A, chromosome 12 at 41,453,788 bp
  • A to G, chromosome 12 at 55,868,185 bp
  • G to T, chromosome 12 at 112,920,349 bp
  • G to A, chromosome 13 at 95,041,959 bp
  • T to A, chromosome 13 at 113,368,806 bp
  • A to G, chromosome 14 at 31,240,863 bp
  • G to A, chromosome 14 at 54,884,745 bp
  • A to G, chromosome 14 at 103,285,400 bp
  • G to A, chromosome 15 at 76,912,085 bp
  • A to T, chromosome 16 at 73,013,068 bp
  • A to G, chromosome 17 at 34,800,288 bp
  • A to G, chromosome 17 at 78,281,309 bp
  • A to G, chromosome 18 at 6,992,888 bp
  • T to A, chromosome 18 at 20,045,430 bp
  • T to C, chromosome 18 at 31,682,091 bp
  • C to A, chromosome 18 at 33,464,305 bp
  • T to C, chromosome 18 at 38,277,859 bp
  • A to G, chromosome 19 at 9,284,015 bp
  • A to T, chromosome 19 at 29,623,209 bp
  • C to T, chromosome X at 74,277,038 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6129 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044276-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.