Strain Name:
C57BL/6J-MtgxR6130Btlr
Stock Number:
044277-MU
Citation ID:
RRID:MMRRC_044277-MU
Other Names:
R6130 (G1)
Major Collection:

Gene Information

Igf2bp1
Name: insulin-like growth factor 2 mRNA binding protein 1
Synonyms: D11Moh40e, D11Moh45, Zbp1, IMP-1, IMP1, Crdbp, CRD-BP, D030026A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 140486
Homologene: 4772
Tmem59l
Name: transmembrane protein 59-like
Synonyms: 5330410G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 67937
Homologene: 8104
Auts2
Name: autism susceptibility candidate 2
Synonyms: 2700063G02Rik, A730011F23Rik, D830032G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 319974
Homologene: 22907
Rsf1
Name: remodeling and spacing factor 1
Synonyms: XAP8, p325, Hbxap, 4832420A03Rik, C030033M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233532
Homologene: 41142
Aen
Name: apoptosis enhancing nuclease
Synonyms: 2700083B06Rik, Isg20l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68048
Homologene: 23382
Ctla4
Name: cytotoxic T-lymphocyte-associated protein 4
Synonyms: Ctla-4, Ly-56, Cd152
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12477
HGNC: HGNC:2505
Homologene: 3820
Robo2
Name: roundabout guidance receptor 2
Synonyms: 2600013A04Rik, 9430089E08Rik, D230004I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 268902
Homologene: 43188
Lepr
Name: leptin receptor
Synonyms: obl, Modb1, Leprb, leptin receptor gene-related protein, obese-like, Obr, LEPROT, OB-RGRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 16847
HGNC: HGNC:6554
Homologene: 1731
Jph3
Name: junctophilin 3
Synonyms: JP-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 57340
Homologene: 10762
Muc16
Name: mucin 16
Synonyms: 1110008I14Rik, LOC385009, Gm21044
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 73732
Homologene: 141193
Hmg20a
Name: high mobility group 20A
Synonyms: 5730490E10Rik, Hmgxb1, 1200004E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 66867
VEGA: 9
HGNC: HGNC:5001
Homologene: 32399
Scin
Name: scinderin
Synonyms: adseverin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20259
Homologene: 36296
Tns2
Name: tensin 2
Synonyms: Tenc1, nph, nep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 209039
VEGA: 15
Homologene: 37077
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: Dnahc6, A730004I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Wdr63
Name: WD repeat domain 63
Synonyms: IC140, Ida7, 4931433A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242253
Homologene: 44922
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: PC5A, b2b585Clo, SPC6, PC5/6A, b2b1549Clo, PC6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Slco1a6
Name: solute carrier organic anion transporter family, member 1a6
Synonyms: Oatp-5, Slc21a13, 4930422F19Rik, organic anion-transporting polypeptide
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28254
Homologene: 23416
Antxr2
Name: anthrax toxin receptor 2
Synonyms: CMG2, cI-35, CMG-2, 2310046B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71914
Homologene: 43236
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: Mass1, Gpr98, VLGR1, Mgr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 110789
Homologene: 19815
Kif1a
Name: kinesin family member 1A
Synonyms: LOC381283, N-3 kinesin, Kns1, C630002N23Rik, ATSV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16560
HGNC: HGNC:888
Homologene: 99729
Scap
Name: SREBF chaperone
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235623
Homologene: 8160
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380698
Homologene: 70869
Abi3
Name: ABI gene family, member 3
Synonyms: 2210414K06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66610
Homologene: 9505
Ccdc39
Name: coiled-coil domain containing 39
Synonyms: D3Ertd789e, 4921507O14Rik, b2b1735Clo, b2b2025.1Clo, prh, b2b1304Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 51938
Homologene: 12149
Flg
Name: filaggrin
Synonyms: profilaggrin, ft, fillagrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 14246
VEGA: 3
Syna
Name: syncytin a
Synonyms: Gm52, syncytin-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 214292
Homologene: 86751
Stil
Name: Scl/Tal1 interrupting locus
Synonyms: Sil
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 20460
Homologene: 2283
Scarf1
Name: scavenger receptor class F, member 1
Synonyms: SREC, SREC-I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380713
Homologene: 2741
Olfr50
Name: olfactory receptor 50
Synonyms: GA_x6K02T2NLDC-33487752-33488690, MOR136-6, ID3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18350
Homologene: 74212
Trpv3
Name: transient receptor potential cation channel, subfamily V, member 3
Synonyms: 1110036I10Rik, Nh, VRL3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 246788
Homologene: 17040
Dennd4b
Name: DENN/MADD domain containing 4B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229541
Homologene: 28281
Sh2b3
Name: SH2B adaptor protein 3
Synonyms: Lnk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16923
Homologene: 36179
4930553M12Rik
Name: RIKEN cDNA 4930553M12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
Ppp1r32
Name: protein phosphatase 1, regulatory subunit 32
Synonyms: 4930579J09Rik, IIIG9S, IIIG9L, IIIG9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 67752
VEGA: 19
Homologene: 15863
Myom3
Name: myomesin family, member 3
Synonyms: 8430427K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242702
Homologene: 19432
Lamc2
Name: laminin, gamma 2
Synonyms: nicein, 100kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16782
HGNC: HGNC:6493
Homologene: 4062
Fpr1
Name: formyl peptide receptor 1
Synonyms: FPR, fMLF-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14293
HGNC: HGNC:3826
Homologene: 20466
Nlrp5
Name: NLR family, pyrin domain containing 5
Synonyms: Nalp5, Mater, Op1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 23968
Homologene: 65105
Gm10549
Name: predicted gene 10549
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 433171
VEGA: 18
Ankrd55
Name: ankyrin repeat domain 55
Synonyms: C030011J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 77318
VEGA: 13
Homologene: 12674
Fbxo6
Name: F-box protein 6
Synonyms: Fbx6b, Fbs2, Fbxo6b, FBG2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 50762
Homologene: 9274
Trappc6a
Name: trafficking protein particle complex 6A
Synonyms: 4930519D19Rik, 1810073E21Rik, TRS33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67091
Homologene: 69370
Olfr318
Name: olfactory receptor 318
Synonyms: MOR285-1, GA_x6K02T2NKPP-692816-693736
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258494
Homologene: 133825
Casd1
Name: CAS1 domain containing 1
Synonyms: Cast1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 213819
Homologene: 11287
Zfp72
Name: zinc finger protein 72
Synonyms: Zfp74
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 238722
VEGA: 13
Homologene: 108290
Fdxacb1
Name: ferredoxin-fold anticodon binding domain containing 1
Synonyms: D630004A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382137
Homologene: 19813
Gsta1
Name: glutathione S-transferase, alpha 1 (Ya)
Synonyms: Gst2-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 14857
Homologene: 74378
Trim21
Name: tripartite motif-containing 21
Synonyms: Ro52, Ssa1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20821
Homologene: 2365
Dnase1l1
Name: deoxyribonuclease 1-like 1
Synonyms: Dnl1ll, 2310005K03Rik, Dnase1ll, G4.8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 69537
HGNC: HGNC:2957
Homologene: 4896
Pcdhga8
Name: protocadherin gamma subfamily A, 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93716
HGNC: HGNC:8706
Homologene: 57162
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 60,912,491 bp
  • T to A, chromosome 1 at 93,036,901 bp
  • T to C, chromosome 1 at 153,136,777 bp
  • A to T, chromosome 2 at 36,794,043 bp
  • T to C, chromosome 3 at 33,841,192 bp
  • T to C, chromosome 3 at 90,276,259 bp
  • A to G, chromosome 3 at 93,292,716 bp
  • A to C, chromosome 3 at 146,042,804 bp
  • T to C, chromosome 4 at 88,868,359 bp
  • A to T, chromosome 4 at 101,765,372 bp
  • T to A, chromosome 4 at 115,029,861 bp
  • A to G, chromosome 4 at 135,762,571 bp
  • A to T, chromosome 4 at 148,149,522 bp
  • T to C, chromosome 5 at 98,004,272 bp
  • T to C, chromosome 5 at 121,815,563 bp
  • T to C, chromosome 5 at 131,440,223 bp
  • T to A, chromosome 5 at 134,558,268 bp
  • A to G, chromosome 6 at 4,641,948 bp
  • T to A, chromosome 6 at 73,188,494 bp
  • T to C, chromosome 6 at 142,086,429 bp
  • G to A, chromosome 7 at 19,515,294 bp
  • A to G, chromosome 7 at 23,404,173 bp
  • A to T, chromosome 7 at 78,902,639 bp
  • G to A, chromosome 7 at 97,579,910 bp
  • A to T, chromosome 7 at 102,563,291 bp
  • A to G, chromosome 8 at 70,484,605 bp
  • G to A, chromosome 8 at 121,753,087 bp
  • A to G, chromosome 9 at 18,590,698 bp
  • C to T, chromosome 9 at 50,772,602 bp
  • T to A, chromosome 9 at 56,488,607 bp
  • T to A, chromosome 9 at 78,242,565 bp
  • A to G, chromosome 9 at 110,380,379 bp
  • A to G, chromosome 11 at 58,720,307 bp
  • A to C, chromosome 11 at 59,077,945 bp
  • A to G, chromosome 11 at 73,296,483 bp
  • A to G, chromosome 11 at 75,525,739 bp
  • T to A, chromosome 11 at 95,837,095 bp
  • A to C, chromosome 11 at 95,974,020 bp
  • T to C, chromosome 12 at 40,069,436 bp
  • T to A, chromosome 13 at 74,372,341 bp
  • A to C, chromosome 13 at 81,427,745 bp
  • A to G, chromosome 13 at 112,318,446 bp
  • A to G, chromosome 15 at 102,111,241 bp
  • C to T, chromosome 16 at 73,920,682 bp
  • T to A, chromosome 17 at 17,877,635 bp
  • C to A, chromosome 18 at 33,464,305 bp
  • T to A, chromosome 18 at 37,727,527 bp
  • G to A, chromosome 19 at 10,477,764 bp
  • A to T, chromosome 19 at 17,511,556 bp
  • C to T, chromosome X at 74,277,038 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6130 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044277-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.