Strain Name:
C57BL/6J-MtgxR6132Btlr
Stock Number:
044279-MU
Citation ID:
RRID:MMRRC_044279-MU
Other Names:
R6132 (G1)
Major Collection:

Gene Information

Otx1
Name: orthodenticle homeobox 1
Synonyms: jv, A730044F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18423
HGNC: HGNC:8521
Homologene: 7875
Nrcam
Name: neuronal cell adhesion molecule
Synonyms: Bravo, C130076O07Rik, C030017F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319504
VEGA: 12
HGNC: HGNC:7994
Homologene: 21041
Omd
Name: osteomodulin
Synonyms: osteoadherin, OSAD, SLRR2C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 27047
VEGA: 13
HGNC: HGNC:8134
Homologene: 3677
Dlg1
Name: discs large MAGUK scaffold protein 1
Synonyms: Dlgh1, B130052P05Rik, SAP97
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 13383
HGNC: HGNC:2900
Homologene: 20869
Tet1
Name: tet methylcytosine dioxygenase 1
Synonyms: D10Ertd17e, 2510010B09Rik, BB001228, Cxxc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 52463
Homologene: 12735
Depdc5
Name: DEP domain containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 277854
Homologene: 34718
Kdm5a
Name: lysine (K)-specific demethylase 5A
Synonyms: RBP2, Rbbp2, Jarid1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 214899
HGNC: HGNC:9886
Homologene: 3419
Exoc4
Name: exocyst complex component 4
Synonyms: Sec8, Sec8l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 20336
Homologene: 40654
Golph3l
Name: golgi phosphoprotein 3-like
Synonyms: GPP34R, 2010204I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229593
Homologene: 23082
Lman2
Name: lectin, mannose-binding 2
Synonyms: 1300009F09Rik, 1110003H06Rik, VIP36, GP36B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66890
VEGA: 13
Homologene: 4962
Esf1
Name: ESF1 nucleolar pre-rRNA processing protein homolog
Synonyms: 2610101J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66580
Homologene: 5717
Rttn
Name: rotatin
Synonyms: C530033I08Rik, 4921538A15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 246102
VEGA: 18
Homologene: 65275
Ddx52
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
Synonyms: 2700029C06Rik, ROK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 78394
Homologene: 5093
Alkbh5
Name: alkB homolog 5, RNA demethylase
Synonyms: Abh5, Ofoxd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268420
Homologene: 9818
Afg3l2
Name: AFG3-like AAA ATPase 2
Synonyms: 2310036I02Rik, Emv66, par
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 69597
VEGA: 18
HGNC: HGNC:315
Homologene: 4947
Erap1
Name: endoplasmic reticulum aminopeptidase 1
Synonyms: PILSAP, Arts1, ERAAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 80898
VEGA: 13
Homologene: 56754
Scn10a
Name: sodium channel, voltage-gated, type X, alpha
Synonyms: Nav1.8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20264
VEGA: 9
Homologene: 21300
Crebrf
Name: CREB3 regulatory factor
Synonyms: A930001N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 77128
Homologene: 12672
Slf2
Name: SMC5-SMC6 complex localization factor 2
Synonyms: Fam178a, 6030443O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226151
VEGA: 19
Homologene: 23077
Zfp457
Name: zinc finger protein 457
Synonyms: Rslcan-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 431706
Homologene: 75311
Otor
Name: otoraplin
Synonyms: Fdp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 57329
HGNC: HGNC:8517
Homologene: 10600
Mkln1
Name: muskelin 1, intracellular mediator containing kelch motifs
Synonyms: A130067F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 27418
HGNC: HGNC:7109
Homologene: 8305
Pwwp2a
Name: PWWP domain containing 2A
Synonyms: D930040F23Rik, 4631424J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 70802
Homologene: 19687
Tarbp1
Name: TAR RNA binding protein 1
Synonyms: Gm17296
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 212728
Homologene: 38082
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: D12Ertd777e, nesprin-2, syne-2, dice, Nesp2g, Cpfl8, diminished cone electroretinogram, 6820443O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319565
Homologene: 56700
Efcab6
Name: EF-hand calcium binding domain 6
Synonyms: 4932408N08Rik, 4931407K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 77627
Homologene: 11259
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Hdhc3, DLP12, Dnahc12, 4921531P07Rik, LOC380889, HL-19, DHC3, HL19, Dnahc7l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Olfr994
Name: olfactory receptor 994
Synonyms: MOR203-4, GA_x6K02T2Q125-46907515-46906571
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258425
Homologene: 17245
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: Mass1, Gpr98, VLGR1, Mgr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 110789
Homologene: 19815
Tnn
Name: tenascin N
Synonyms: tenascin-W, Tnw
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329278
Homologene: 18634
Abca15
Name: ATP-binding cassette, sub-family A (ABC1), member 15
Synonyms: 4930500I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 320631
Homologene: 87255
Fbxo44
Name: F-box protein 44
Synonyms: FBX30, FBG3, Fbx6a, Fbxo6a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230903
Homologene: 13232
Gprc6a
Name: G protein-coupled receptor, family C, group 6, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 210198
VEGA: 10
Homologene: 17529
Olfr201
Name: olfactory receptor 201
Synonyms: GA_x54KRFPKG5P-55483936-55483010, MOR182-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258996
Homologene: 37011
Sema3a
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
Synonyms: collapsin-1, Semad, SemD, semaphorin III, sema III
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20346
Homologene: 31358
Sel1l3
Name: sel-1 suppressor of lin-12-like 3 (C. elegans)
Synonyms: 2310045A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231238
Homologene: 9054
Dhx30
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 30
Synonyms: Ddx30, 2810477H02Rik, C130058C04Rik, helG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 72831
Homologene: 15779
Map3k19
Name: mitogen-activated protein kinase kinase kinase 19
Synonyms: Ysk4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22625
Homologene: 19318
Tsr3
Name: TSR3 20S rRNA accumulation
Synonyms: 1110014B11Rik, 0610007P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 68327
VEGA: 17
Homologene: 6922
1110017D15Rik
Name: RIKEN cDNA 1110017D15 gene
Synonyms: Cbe1, Smrp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 73721
Homologene: 13074
Vmn2r106
Name: vomeronasal 2, receptor 106
Synonyms: EG224576
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224576
Homologene: 135824
S1pr4
Name: sphingosine-1-phosphate receptor 4
Synonyms: S1P4, lpC1, Edg6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13611
VEGA: 10
HGNC: HGNC:3170
Homologene: 2799
Grin3b
Name: glutamate receptor, ionotropic, NMDA3B
Synonyms: NR3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 170483
Homologene: 15606
Cyp2c68
Name: cytochrome P450, family 2, subfamily c, polypeptide 68
Synonyms: 9030012A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 433247
Homologene: 74936
Oacyl
Name: O-acyltransferase like
Synonyms: 5330437I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 319888
Homologene: 129774
Gal3st2b
Name: galactose-3-O-sulfotransferase 2B
Synonyms: Gm9994
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 100041596
Homologene: 41471
Olfr883
Name: olfactory receptor 883
Synonyms: MOR162-6, GA_x6K02T2PVTD-31705144-31706073
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258414
Homologene: 86689
Mmel1
Name: membrane metallo-endopeptidase-like 1
Synonyms: Nep2, NEPLP beta, NEPLP alpha, SEP, Nl1, Mell1, NEPLP gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 27390
Homologene: 22778
Tollip
Name: toll interacting protein
Synonyms: Toll interacting protein, 4930403G24Rik, 4931428G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 54473
Homologene: 10375
Nova2
Name: NOVA alternative splicing regulator 2
Synonyms: LOC384569
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 384569
HGNC: HGNC:7887
Homologene: 134398
Ctsr
Name: cathepsin R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 56835
VEGA: 13
Homologene: 75127
Atp5g1
Name: ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11951
HGNC: HGNC:841
Homologene: 38017
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 93,939,966 bp
  • T to C, chromosome 1 at 127,850,476 bp
  • A to G, chromosome 1 at 160,146,071 bp
  • A to T, chromosome 2 at 85,430,146 bp
  • A to G, chromosome 2 at 140,159,779 bp
  • A to T, chromosome 2 at 143,078,600 bp
  • C to G, chromosome 3 at 95,591,834 bp
  • C to T, chromosome 4 at 41,517,160 bp
  • G to A, chromosome 4 at 148,156,108 bp
  • C to T, chromosome 4 at 154,895,018 bp
  • T to G, chromosome 5 at 13,523,175 bp
  • T to A, chromosome 5 at 32,910,467 bp
  • T to C, chromosome 5 at 53,200,189 bp
  • G to A, chromosome 6 at 31,431,220 bp
  • A to G, chromosome 6 at 33,758,098 bp
  • C to T, chromosome 6 at 120,374,931 bp
  • G to A, chromosome 7 at 18,957,869 bp
  • T to C, chromosome 7 at 120,361,420 bp
  • A to G, chromosome 7 at 141,889,597 bp
  • T to A, chromosome 8 at 126,434,809 bp
  • ATTGCTGTTT to ATTGCTGTTTGCTGTTT, chromosome 9 at 38,026,540 bp
  • A to T, chromosome 9 at 110,085,779 bp
  • C to T, chromosome 9 at 119,613,695 bp
  • T to A, chromosome 10 at 51,615,260 bp
  • A to C, chromosome 10 at 62,813,300 bp
  • T to C, chromosome 10 at 79,976,440 bp
  • G to A, chromosome 10 at 81,499,196 bp
  • A to T, chromosome 11 at 21,999,406 bp
  • A to G, chromosome 11 at 43,705,628 bp
  • G to T, chromosome 11 at 60,537,995 bp
  • A to G, chromosome 11 at 83,959,457 bp
  • A to G, chromosome 11 at 96,075,024 bp
  • T to A, chromosome 12 at 44,570,224 bp
  • T to C, chromosome 12 at 75,945,147 bp
  • A to C, chromosome 13 at 49,590,367 bp
  • A to G, chromosome 13 at 55,362,225 bp
  • A to C, chromosome 13 at 61,161,768 bp
  • G to T, chromosome 13 at 67,293,296 bp
  • A to G, chromosome 13 at 74,660,282 bp
  • G to T, chromosome 13 at 81,506,076 bp
  • T to A, chromosome 14 at 26,717,911 bp
  • A to G, chromosome 15 at 84,032,972 bp
  • A to T, chromosome 16 at 31,836,241 bp
  • A to G, chromosome 16 at 59,269,004 bp
  • T to C, chromosome 17 at 20,268,404 bp
  • G to T, chromosome 17 at 25,241,861 bp
  • C to T, chromosome 17 at 26,763,403 bp
  • G to T, chromosome 18 at 65,726,355 bp
  • G to T, chromosome 18 at 67,421,259 bp
  • T to A, chromosome 18 at 89,115,646 bp
  • A to G, chromosome 19 at 39,703,414 bp
  • T to A, chromosome 19 at 44,960,861 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6132 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044279-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.