Strain Name:
C57BL/6J-MtgxR6150Btlr
Stock Number:
044297-MU
Citation ID:
RRID:MMRRC_044297-MU
Other Names:
R6150 (G1)
Major Collection:

Gene Information

Kl
Name: klotho
Synonyms: alpha-kl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16591
HGNC: HGNC:6344
Homologene: 68415
Eps8
Name: epidermal growth factor receptor pathway substrate 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 13860
HGNC: HGNC:3420
Homologene: 3272
Kif13b
Name: kinesin family member 13B
Synonyms: 5330429L19Rik, N-3 kinesin, GAKIN, C130021D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16554
VEGA: 14
Homologene: 9073
Vangl1
Name: VANGL planar cell polarity 1
Synonyms: mStbm, stbm, Lpp2, KITENIN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229658
Homologene: 44540
Prpf40a
Name: pre-mRNA processing factor 40A
Synonyms: FBP11, 2810012K09Rik, Fnbp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56194
Homologene: 6377
Tex2
Name: testis expressed gene 2
Synonyms: Taz4, Def-5, 4930568E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 21763
Homologene: 32414
F2rl3
Name: coagulation factor II (thrombin) receptor-like 3
Synonyms: PAR4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14065
HGNC: HGNC:3540
Homologene: 36148
Vps18
Name: VPS18 CORVET/HOPS core subunit
Synonyms: 9930024E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228545
Homologene: 13302
Slc6a11
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 11
Synonyms: Gat3, E130202I16Rik, GAT4, Gabt4, D930045G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243616
Homologene: 129935
Slit2
Name: slit guidance ligand 2
Synonyms: Slil3, b2b1200.1Clo, Drad-1, E130320P19Rik, E030015M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20563
Homologene: 3516
Arhgef1
Name: Rho guanine nucleotide exchange factor (GEF) 1
Synonyms: Lsc, Lbcl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16801
HGNC: HGNC:681
Homologene: 3454
Ube2v1
Name: ubiquitin-conjugating enzyme E2 variant 1
Synonyms: D7Bwg1382e, CROC1, 0610011J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66589
Homologene: 81888
Erc2
Name: ELKS/RAB6-interacting/CAST family member 2
Synonyms: ELKS2alpha, CAST, D14Ertd171e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 238988
Homologene: 69188
Srcap
Name: Snf2-related CREBBP activator protein
Synonyms: B930091H02Rik, F630004O05Rik, D030022P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100043597
Homologene: 38213
Pmpcb
Name: peptidase (mitochondrial processing) beta
Synonyms: MPP11, MPPP52, 3110004O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 73078
HGNC: HGNC:9119
Homologene: 3160
Cutc
Name: cutC copper transporter
Synonyms: CGI-32, 2310039I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 66388
Homologene: 9318
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Olfr800
Name: olfactory receptor 800
Synonyms: MOR114-7, GA_x6K02T2PULF-11338429-11339364
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258541
Homologene: 27203
Kmt2b
Name: lysine (K)-specific methyltransferase 2B
Synonyms: Wbp7, 2610014H22Rik, Mll2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 75410
Homologene: 22838
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243369
Homologene: 45453
Kcnh6
Name: potassium voltage-gated channel, subfamily H (eag-related), member 6
Synonyms: m-erg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 192775
Homologene: 32740
Supv3l1
Name: suppressor of var1, 3-like 1 (S. cerevisiae)
Synonyms: 6330443E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 338359
Homologene: 2386
Dtx1
Name: deltex 1, E3 ubiquitin ligase
Synonyms: Fxit1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14357
HGNC: HGNC:3060
Homologene: 74522
Itga1
Name: integrin alpha 1
Synonyms: CD49A, E130012M19Rik, Vla1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 109700
VEGA: 13
HGNC: HGNC:6134
Homologene: 57137
Tmem184c
Name: transmembrane protein 184C
Synonyms: 8430433H16Rik, Tmem34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234463
Homologene: 32403
Vmn2r114
Name: vomeronasal 2, receptor 114
Synonyms: EG666002
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 666002
Homologene: 86604
Fam83b
Name: family with sequence similarity 83, member B
Synonyms: C530008M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 208994
Homologene: 19478
Zfp521
Name: zinc finger protein 521
Synonyms: B930086A16Rik, Evi3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225207
VEGA: 18
Homologene: 9151
Igsf11
Name: immunoglobulin superfamily, member 11
Synonyms: BT-IgSF, 1700025L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 207683
Homologene: 17613
Kif26b
Name: kinesin family member 26B
Synonyms: D230039L06Rik, N-11 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 269152
Homologene: 18623
Itgav
Name: integrin alpha V
Synonyms: D430040G12Rik, 1110004F14Rik, 2610028E01Rik, vitronectin receptor alpha polypeptide (VNRA), alphav-integrin, CD51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16410
HGNC: HGNC:6150
Homologene: 20510
Vmn1r61
Name: vomeronasal 1 receptor 61
Synonyms: Gm7186
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 636731
Homologene: 41799
Jmy
Name: junction-mediating and regulatory protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 57748
VEGA: 13
Homologene: 10955
Six5
Name: sine oculis-related homeobox 5
Synonyms: MDMAHP, Dmahp, TrexBF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20475
Homologene: 72248
Usp45
Name: ubiquitin specific petidase 45
Synonyms: Gcap7, 3110003C05Rik, 4930550B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 77593
Homologene: 17674
Olfr370
Name: olfactory receptor 370
Synonyms: MOR267-16, GA_x6K02T2NUPS-11609807-11610751
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 258267
Homologene: 74037
Hivep3
Name: human immunodeficiency virus type I enhancer binding protein 3
Synonyms: Krc, E030045D18Rik, Schnurri-3, 2900056N03Rik, Shn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 16656
Homologene: 7803
Tekt3
Name: tektin 3
Synonyms: 4933407G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71062
Homologene: 12896
Cep44
Name: centrosomal protein 44
Synonyms: 4933440G23Rik, BC088983
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 382010
Homologene: 12738
Mau2
Name: MAU2 sister chromatid cohesion factor
Synonyms: A930019L04Rik, 9130404D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74549
Homologene: 12574
Myb
Name: myeloblastosis oncogene
Synonyms: c-myb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 17863
HGNC: HGNC:7545
Homologene: 31311
Aldh3a1
Name: aldehyde dehydrogenase family 3, subfamily A1
Synonyms: Ahd4, Ahd-4, Aldh3, Aldh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11670
HGNC: HGNC:405
Homologene: 20175
Fitm2
Name: fat storage-inducing transmembrane protein 2
Synonyms: Fit2, D930001I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228859
Homologene: 35254
Serpina1e
Name: serine (or cysteine) peptidase inhibitor, clade A, member 1E
Synonyms: Spi1-5, PI5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20704
HGNC: HGNC:8941
Homologene: 20103
Slc17a9
Name: solute carrier family 17, member 9
Synonyms: 1700019H03Rik, Vnut
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228993
Homologene: 76562
Slc37a2
Name: solute carrier family 37 (glycerol-3-phosphate transporter), member 2
Synonyms: G3PP, cI-2, ci2, Slc37a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 56857
Homologene: 41357
Vgll3
Name: vestigial like family member 3
Synonyms: Vito-2, 1700110N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 73569
VEGA: 16
Homologene: 53442
Art1
Name: ADP-ribosyltransferase 1
Synonyms: ADPRT, Yac-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11870
HGNC: HGNC:723
Homologene: 128621
Pla2g4d
Name: phospholipase A2, group IVD
Synonyms: 2610311B01Rik, Pla2delta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78390
Homologene: 52252
Olfr867
Name: olfactory receptor 867
Synonyms: GA_x6K02T2PVTD-13795933-13794938, MOR143-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 257898
Homologene: 128152
Map10
Name: microtubule-associated protein 10
Synonyms: 4933403G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74393
Homologene: 10416
Zfp971
Name: zinc finger protein 971
Synonyms: Etohi1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 626848
Homologene: 134324
Pomk
Name: protein-O-mannose kinase
Synonyms: Sgk196, 4930444A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74653
Homologene: 12580
Olfr399
Name: olfactory receptor 399
Synonyms: GA_x6K02T2P1NL-4211516-4210581, MOR255-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 259006
Homologene: 27325
Ifna1
Name: interferon alpha 1
Synonyms: Ifa1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 15962
HGNC: HGNC:5425
Homologene: 68536
Fxyd1
Name: FXYD domain-containing ion transport regulator 1
Synonyms: 1110006M24Rik, 0610012C17Rik, PML, PLM, phospholemman
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56188
HGNC: HGNC:4025
Homologene: 3691
Vmn2r35
Name: vomeronasal 2, receptor 35
Synonyms: EG625353
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 625353
Homologene: 113703
Boll
Name: boule homolog, RNA binding protein
Synonyms: 4930597B14Rik, 4930554P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 75388
Homologene: 33650
Naaladl2
Name: N-acetylated alpha-linked acidic dipeptidase-like 2
Synonyms: EG635702, 2810043G22Rik, LOC381500
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 635702
Homologene: 45786
Gm17186
Name: predicted gene 17186
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 55,270,653 bp
  • T to C, chromosome 1 at 178,915,546 bp
  • T to C, chromosome 2 at 53,157,915 bp
  • T to C, chromosome 2 at 83,776,436 bp
  • T to A, chromosome 2 at 119,297,592 bp
  • T to C, chromosome 2 at 120,269,564 bp
  • A to G, chromosome 2 at 163,470,074 bp
  • G to A, chromosome 2 at 167,617,954 bp
  • A to C, chromosome 2 at 178,033,454 bp
  • A to G, chromosome 2 at 180,737,628 bp
  • C to A, chromosome 3 at 24,552,050 bp
  • T to C, chromosome 3 at 102,184,519 bp
  • A to C, chromosome 4 at 21,810,797 bp
  • T to A, chromosome 4 at 88,850,112 bp
  • C to A, chromosome 4 at 119,734,077 bp
  • A to G, chromosome 5 at 21,737,139 bp
  • A to T, chromosome 5 at 48,304,174 bp
  • T to C, chromosome 5 at 120,681,363 bp
  • T to A, chromosome 5 at 150,988,853 bp
  • T to C, chromosome 6 at 48,486,379 bp
  • T to A, chromosome 6 at 114,245,618 bp
  • A to T, chromosome 6 at 137,517,174 bp
  • T to A, chromosome 7 at 5,610,679 bp
  • A to T, chromosome 7 at 7,786,556 bp
  • C to T, chromosome 7 at 19,097,521 bp
  • T to C, chromosome 7 at 24,919,357 bp
  • G to T, chromosome 7 at 30,588,477 bp
  • T to C, chromosome 7 at 31,054,803 bp
  • A to G, chromosome 7 at 46,264,059 bp
  • C to G, chromosome 7 at 102,107,087 bp
  • T to A, chromosome 7 at 127,534,828 bp
  • A to G, chromosome 8 at 25,983,256 bp
  • T to C, chromosome 8 at 56,539,805 bp
  • A to T, chromosome 8 at 70,019,837 bp
  • G to T, chromosome 8 at 72,762,738 bp
  • G to T, chromosome 8 at 77,596,440 bp
  • G to A, chromosome 8 at 83,541,153 bp
  • G to A, chromosome 8 at 125,671,589 bp
  • A to T, chromosome 9 at 20,054,874 bp
  • G to T, chromosome 9 at 37,238,347 bp
  • G to A, chromosome 9 at 76,492,357 bp
  • A to G, chromosome 10 at 21,141,769 bp
  • A to T, chromosome 10 at 62,435,722 bp
  • A to G, chromosome 10 at 129,659,934 bp
  • A to G, chromosome 11 at 61,213,508 bp
  • A to T, chromosome 11 at 63,094,657 bp
  • A to C, chromosome 11 at 74,054,319 bp
  • G to A, chromosome 11 at 106,020,731 bp
  • A to T, chromosome 11 at 106,567,080 bp
  • A to G, chromosome 12 at 103,950,807 bp
  • A to T, chromosome 13 at 93,441,133 bp
  • G to A, chromosome 13 at 114,968,233 bp
  • C to A, chromosome 14 at 28,141,291 bp
  • T to C, chromosome 14 at 51,680,726 bp
  • T to A, chromosome 14 at 64,751,639 bp
  • G to A, chromosome 16 at 39,023,349 bp
  • T to A, chromosome 16 at 65,828,178 bp
  • A to G, chromosome 17 at 23,291,295 bp
  • A to T, chromosome 18 at 13,844,078 bp
  • T to A, chromosome 19 at 43,759,889 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6150 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044297-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.