Strain Name:
C57BL/6J-MtgxR6158Btlr
Stock Number:
044305-MU
Citation ID:
RRID:MMRRC_044305-MU
Other Names:
R6158 (G1)
Major Collection:

Gene Information

Utrn
Name: utrophin
Synonyms: G-utrophin, Dmdl, DRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22288
VEGA: 10
Homologene: 21398
Wrn
Name: Werner syndrome RecQ like helicase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 22427
Homologene: 6659
Nos1
Name: nitric oxide synthase 1, neuronal
Synonyms: nNOS, bNOS, Nos-1, NO, 2310005C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18125
HGNC: HGNC:7872
Homologene: 37327
Kl
Name: klotho
Synonyms: alpha-kl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 16591
HGNC: HGNC:6344
Homologene: 68415
Nsd1
Name: nuclear receptor-binding SET-domain protein 1
Synonyms: KMT3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18193
VEGA: 13
Homologene: 32543
Ccdc58
Name: coiled-coil domain containing 58
Synonyms: A930007B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 381045
VEGA: 16
Homologene: 18028
Synj2
Name: synaptojanin 2
Synonyms: SJ2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20975
Homologene: 117703
Rock2
Name: Rho-associated coiled-coil containing protein kinase 2
Synonyms: Rock-II, B230113H15Rik, Rho-kinase, ROKalpha, Rock2m
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19878
VEGA: 12
Homologene: 21010
Znfx1
Name: zinc finger, NFX1-type containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 98999
Homologene: 10877
Aurka
Name: aurora kinase A
Synonyms: Ayk1, Ark1, IAK, AIRK1, aurora A, Aurora-A, Stk6, IAK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20878
Homologene: 2670
St13
Name: suppression of tumorigenicity 13
Synonyms: PRO0786, HSPABP1, SNC6, p48, Hsp70 interacting protein, 3110002K08Rik, 1110007I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70356
Homologene: 2921
Tpx2
Name: TPX2, microtubule-associated
Synonyms: REPP86, DIL2, p100, 2610005B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72119
HGNC: HGNC:1249
Homologene: 8107
Fry
Name: FRY microtubule binding protein
Synonyms: cg003, 9330186A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320365
Homologene: 113770
Swap70
Name: SWA-70 protein
Synonyms: 70kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20947
Homologene: 7557
Tom1l2
Name: target of myb1-like 2 (chicken)
Synonyms: 2900016I08Rik, myb1-like protein 2, A730055F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216810
Homologene: 44901
Trip12
Name: thyroid hormone receptor interactor 12
Synonyms: Gtl6, 1110036I07Rik, 6720416K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14897
Homologene: 44226
Tmem87a
Name: transmembrane protein 87A
Synonyms: A930025J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 211499
Homologene: 9165
Zfp472
Name: zinc finger protein 472
Synonyms: Krim-1, Krim-1B, Krim-1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224691
Homologene: 77422
Tmem135
Name: transmembrane protein 135
Synonyms: 2810439K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72759
Homologene: 11295
Slc39a2
Name: solute carrier family 39 (zinc transporter), member 2
Synonyms: zip2, F730005G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 214922
Homologene: 40957
Piwil1
Name: piwi-like RNA-mediated gene silencing 1
Synonyms: MIWI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 57749
HGNC: HGNC:9007
Homologene: 37963
Mastl
Name: microtubule associated serine/threonine kinase-like
Synonyms: THC2, 2700091H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67121
Homologene: 12086
Lmo7
Name: LIM domain only 7
Synonyms: LOC380928, FBXO20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
C1qtnf5
Name: C1q and tumor necrosis factor related protein 5
Synonyms: CTRP5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235312
Homologene: 9227
Htt
Name: huntingtin
Synonyms: huntingtin, HD, htt, IT15, C430023I11Rik, Hdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15194
HGNC: HGNC:4851
Homologene: 1593
Snrnp48
Name: small nuclear ribonucleoprotein 48 (U11/U12)
Synonyms: 1110050F08Rik, 6530403A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67797
VEGA: 13
Homologene: 12191
2700049A03Rik
Name: RIKEN cDNA 2700049A03 gene
Synonyms: talpid3, Ta3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76967
Homologene: 8839
Ttyh1
Name: tweety family member 1
Synonyms: tty, 6330408P11Rik, 4930459B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57776
Homologene: 10779
Moxd1
Name: monooxygenase, DBH-like 1
Synonyms: 3230402N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 59012
Homologene: 22904
Gngt1
Name: guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
Synonyms: G(y)1, Gng1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14699
HGNC: HGNC:4411
Homologene: 7738
Zfp831
Name: zinc finger protein 831
Synonyms: ENSMUSG00000050600, OTTMUSG00000017459
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 100043757
Homologene: 19013
2900092C05Rik
Name: RIKEN cDNA 2900092C05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73090
Homologene: 49900
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Hdhc3, HL-19, DLP12, HL19, DHC3, LOC380889, 4921531P07Rik, Dnahc7l, Dnahc12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Col7a1
Name: collagen, type VII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12836
HGNC: HGNC:2214
Homologene: 73
Pdzph1
Name: PDZ and pleckstrin homology domains 1
Synonyms: 2610034M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 69239
Homologene: 130756
Ralgapa2
Name: Ral GTPase activating protein, alpha subunit 2 (catalytic)
Synonyms: A230067G21Rik, RGC2, AS250
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241694
Homologene: 28131
Mgam
Name: maltase-glucoamylase
Synonyms: 6030407P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232714
HGNC: HGNC:7043
Homologene: 130099
Or2aj5
Name: olfactory receptor family 2 subfamily AJ member 5
Synonyms: GA_x54KRFPKG5P-16052703-16051765, MOR273-2, Olfr170
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258959
Homologene: 128058
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329628
Homologene: 14377
Cpne8
Name: copine VIII
Synonyms: 1200003E11Rik, 1500031E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 66871
Homologene: 12049
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Specc1
Name: sperm antigen with calponin homology and coiled-coil domains 1
Synonyms: 2810012G08Rik, B230396K10Rik, Cytsb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432572
Homologene: 45157
Vwce
Name: von Willebrand factor C and EGF domains
Synonyms: 1300015B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 71768
VEGA: 19
Homologene: 17651
Dnm3
Name: dynamin 3
Synonyms: B230343F03Rik, 9630020E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 103967
Homologene: 22906
Vmn2r63
Name: vomeronasal 2, receptor 63
Synonyms: EG435975
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 435975
Homologene: 104832
Mei4
Name: meiotic double-stranded break formation protein 4
Synonyms: 4930486G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75033
Homologene: 87251
Or1j15
Name: olfactory receptor family 1 subfamily J member 15
Synonyms: GA_x6K02T2NLDC-33262744-33263673, MOR136-12, Olfr344
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258621
Dhx30
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 30
Synonyms: Ddx30, 2810477H02Rik, C130058C04Rik, helG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72831
Homologene: 15779
Frmpd1
Name: FERM and PDZ domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 666060
Homologene: 8939
Cacnb2
Name: calcium channel, voltage-dependent, beta 2 subunit
Synonyms: Cchb2, Cavbeta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12296
HGNC: HGNC:1402
Homologene: 75191
Rgsl1
Name: regulator of G-protein signaling like 1
Synonyms: 4930415K13Rik, Rgsl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240816
Homologene: 129962
Adprhl1
Name: ADP-ribosylhydrolase like 1
Synonyms: Arh2, D330008N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234072
Homologene: 16311
Myo18b
Name: myosin XVIIIb
Synonyms: 4932408L24Rik, 4933411E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74376
Homologene: 53435
Scg2
Name: secretogranin II
Synonyms: SgII, Chgc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20254
Homologene: 2591
Ano3
Name: anoctamin 3
Synonyms: B230324K02Rik, Tmem16c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228432
Homologene: 57147
Spaca1
Name: sperm acrosome associated 1
Synonyms: 1700124L11Rik, 4930540L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67652
Homologene: 12170
Arhgap24
Name: Rho GTPase activating protein 24
Synonyms: 0610025G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231532
Homologene: 32754
Pla2g4f
Name: phospholipase A2, group IVF
Synonyms: 4732472I07Rik, Pla2zeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 271844
Homologene: 77933
Or5t15
Name: olfactory receptor family 5 subfamily T member 15
Synonyms: GA_x6K02T2Q125-48336843-48335917, MOR179-1, Olfr1095
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258725
Homologene: 28042
Vmn1r8
Name: vomeronasal 1 receptor 8
Synonyms: V1rc32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171205
Homologene: 83427
Or4c11c
Name: olfactory receptor family 4 subfamily C member 11C
Synonyms: GA_x6K02T2Q125-50304328-50305251, GA_x6K02T2Q125-50336588-50337313, MOR230-3, MOR230-1, Olfr1203, Olfr1205
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258898
Homologene: 81567
Mettl27
Name: methyltransferase like 27
Synonyms: Wbscr27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 79565
Homologene: 11553
Or8g50
Name: olfactory receptor family 8 subfamily G member 50
Synonyms: M93, MOR171-18, GA_x6K02T2PVTD-33434302-33435240, Olfr150
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258602
VEGA: 9
Rnf186
Name: ring finger protein 186
Synonyms: 9130020G10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66825
Homologene: 10404
Gm11565
Name: predicted gene 11565
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 670550
Homologene: 134336
Chchd5
Name: coiled-coil-helix-coiled-coil-helix domain containing 5
Synonyms: 1110027L01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66170
Homologene: 11929
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 79,435,400 bp
  • A to T, chromosome 1 at 84,761,012 bp
  • T to C, chromosome 1 at 153,804,021 bp
  • T to C, chromosome 1 at 162,320,987 bp
  • A to G, chromosome 2 at 14,985,601 bp
  • G to T, chromosome 2 at 23,132,772 bp
  • A to T, chromosome 2 at 36,569,116 bp
  • A to G, chromosome 2 at 86,851,515 bp
  • T to C, chromosome 2 at 88,831,146 bp
  • A to T, chromosome 2 at 110,665,875 bp
  • T to C, chromosome 2 at 120,301,071 bp
  • A to T, chromosome 2 at 120,360,103 bp
  • T to C, chromosome 2 at 129,130,517 bp
  • A to T, chromosome 2 at 146,424,676 bp
  • C to A, chromosome 2 at 152,873,104 bp
  • G to T, chromosome 2 at 167,056,726 bp
  • A to C, chromosome 2 at 172,363,596 bp
  • A to T, chromosome 2 at 174,643,858 bp
  • A to T, chromosome 3 at 38,983,262 bp
  • A to G, chromosome 4 at 34,029,176 bp
  • A to T, chromosome 4 at 45,285,401 bp
  • A to G, chromosome 4 at 138,967,254 bp
  • T to C, chromosome 5 at 34,907,086 bp
  • A to T, chromosome 5 at 102,892,912 bp
  • A to T, chromosome 5 at 112,874,172 bp
  • A to C, chromosome 5 at 117,867,574 bp
  • T to A, chromosome 5 at 128,747,876 bp
  • C to T, chromosome 5 at 134,940,576 bp
  • T to C, chromosome 5 at 150,454,572 bp
  • T to A, chromosome 5 at 150,988,853 bp
  • A to T, chromosome 6 at 3,994,311 bp
  • T to A, chromosome 6 at 40,757,714 bp
  • T to A, chromosome 6 at 57,036,289 bp
  • A to G, chromosome 7 at 4,125,562 bp
  • A to G, chromosome 7 at 12,512,672 bp
  • T to A, chromosome 7 at 42,933,680 bp
  • T to A, chromosome 7 at 89,156,444 bp
  • T to A, chromosome 7 at 110,270,023 bp
  • C to T, chromosome 8 at 13,224,977 bp
  • G to T, chromosome 8 at 33,319,172 bp
  • C to T, chromosome 9 at 39,737,076 bp
  • A to T, chromosome 9 at 44,108,970 bp
  • G to T, chromosome 9 at 81,927,576 bp
  • G to T, chromosome 9 at 108,964,603 bp
  • A to T, chromosome 9 at 110,087,030 bp
  • C to T, chromosome 10 at 12,690,822 bp
  • T to A, chromosome 10 at 24,284,777 bp
  • C to T, chromosome 11 at 60,232,927 bp
  • T to G, chromosome 11 at 62,118,124 bp
  • T to A, chromosome 11 at 99,914,918 bp
  • A to G, chromosome 12 at 16,954,918 bp
  • T to C, chromosome 12 at 71,170,636 bp
  • T to A, chromosome 13 at 38,210,236 bp
  • T to C, chromosome 13 at 55,245,621 bp
  • A to T, chromosome 14 at 26,773,685 bp
  • G to A, chromosome 14 at 51,894,224 bp
  • T to A, chromosome 14 at 101,900,137 bp
  • A to T, chromosome 15 at 81,399,601 bp
  • A to C, chromosome 15 at 90,571,988 bp
  • C to A, chromosome 16 at 19,605,925 bp
  • T to A, chromosome 16 at 36,089,929 bp
  • A to G, chromosome 17 at 5,986,212 bp
  • T to A, chromosome 17 at 32,978,389 bp
  • T to G, chromosome 17 at 58,973,627 bp
  • T to C, chromosome 18 at 31,988,549 bp
  • C to T, chromosome 19 at 10,644,221 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6158 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044305-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.