Strain Name:
C57BL/6J-MtgxR6159Btlr/Mmmh
Stock Number:
044306-MU
Citation ID:
RRID:MMRRC_044306-MU
Other Names:
R6159 (G1)
Major Collection:

Gene Information

Ahcyl2
Name: S-adenosylhomocysteine hydrolase-like 2
Synonyms: 4631427C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74340
Homologene: 69337
Rbm47
Name: RNA binding motif protein 47
Synonyms: 9530077J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 245945
Homologene: 36932
Synj2
Name: synaptojanin 2
Synonyms: SJ2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20975
Homologene: 117703
Dock6
Name: dedicator of cytokinesis 6
Synonyms: 2410095B20Rik, 4931431C02Rik, C330023D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319899
VEGA: 9
Homologene: 83291
Med27
Name: mediator complex subunit 27
Synonyms: 1500015J03Rik, 2310042P07Rik, D2Ertd434e, Crsp8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68975
HGNC: HGNC:2377
Homologene: 3152
Nasp
Name: nuclear autoantigenic sperm protein (histone-binding)
Synonyms: Epcs32, 5033430J04Rik, D4Ertd767e, Nasp-T
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 50927
HGNC: HGNC:7644
Homologene: 133894
Fip1l1
Name: FIP1 like 1 (S. cerevisiae)
Synonyms: Rje, 1300019H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66899
Homologene: 136254
Psmc5
Name: protease (prosome, macropain) 26S subunit, ATPase 5
Synonyms: mSUG1, Rpt6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19184
HGNC: HGNC:9552
Homologene: 2098
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21819
Homologene: 2430
Taf2
Name: TATA-box binding protein associated factor 2
Synonyms: TAFII150, CIF150, TAF2B, 4732460C16Rik, 150kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 319944
VEGA: 15
Homologene: 31137
Txnrd3
Name: thioredoxin reductase 3
Synonyms: TR2, Tgr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232223
Homologene: 60033
Tlr4
Name: toll-like receptor 4
Synonyms: Lps, Rasl2-8, lipopolysaccharide response
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21898
Homologene: 41317
Rasal1
Name: RAS protein activator like 1 (GAP1 like)
Synonyms: MRASAL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19415
HGNC: HGNC:9873
Homologene: 3423
Gm14496
Name: predicted gene 14496
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 672125
Homologene: 129606
Htt
Name: huntingtin
Synonyms: huntingtin, HD, htt, IT15, C430023I11Rik, Hdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15194
HGNC: HGNC:4851
Homologene: 1593
Pbrm1
Name: polybromo 1
Synonyms: BAF180, 2610016F04Rik, 2310032M22Rik, Pb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66923
Homologene: 10044
Trim37
Name: tripartite motif-containing 37
Synonyms: MUL, TEF3, 2810004E07Rik, 1110032A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68729
HGNC: HGNC:7523
Homologene: 9084
Klhl20
Name: kelch-like 20
Synonyms: D930050H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226541
Homologene: 8699
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, 2900022L05Rik, Dnhd3, Dnahc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Col28a1
Name: collagen, type XXVIII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 213945
Homologene: 66345
Plek
Name: pleckstrin
Synonyms: 2010300B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 56193
HGNC: HGNC:9070
Homologene: 2000
Chrnd
Name: cholinergic receptor, nicotinic, delta polypeptide
Synonyms: Achr-4, Acrd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11447
HGNC: HGNC:1965
Homologene: 37340
Col4a1
Name: collagen, type IV, alpha 1
Synonyms: Col4a-1, Del(8)Bru44H, Del(8)44H, Bru, Svc, Raw, alpha1(IV) collagen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12826
HGNC: HGNC:2202
Homologene: 20437
Pigs
Name: phosphatidylinositol glycan anchor biosynthesis, class S
Synonyms: LOC276846, LOC245087
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 276846
Homologene: 41963
Olfr121
Name: olfactory receptor 121
Synonyms: MOR263-4, GA_x6K02T2PSCP-2211113-2212078
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258622
Homologene: 17195
Sntb1
Name: syntrophin, basic 1
Synonyms: beta1-Syntrophin, 59-1 DAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20649
Homologene: 9618
Cabs1
Name: calcium binding protein, spermatid specific 1
Synonyms: 4931407G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70977
Homologene: 13225
Vmn2r55
Name: vomeronasal 2, receptor 55
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100042499
Homologene: 104040
Sh3rf2
Name: SH3 domain containing ring finger 2
Synonyms: RNF158, 9130023G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 269016
Homologene: 17618
Olfr1505
Name: olfactory receptor 1505
Synonyms: GA_x6K02T2RE5P-4250267-4251217, MOR211-4P, MOR211-10_i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258151
Homologene: 17394
Dab2
Name: disabled 2, mitogen-responsive phosphoprotein
Synonyms: D15Wsu122e, 5730435J12Rik, p96, D630005B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 13132
HGNC: HGNC:2662
Homologene: 1026
Ankzf1
Name: ankyrin repeat and zinc finger domain containing 1
Synonyms: 1300008P06Rik, 2810025E10Rik, D1Ertd161e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 52231
Homologene: 41225
Sned1
Name: sushi, nidogen and EGF-like domains 1
Synonyms: 6720455I24Rik, Snep, D430044C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 208777
Homologene: 14708
Gbp2
Name: guanylate binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14469
HGNC: HGNC:4183
Homologene: 10289
Qrsl1
Name: glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
Synonyms: GatA, 2700038P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 76563
Homologene: 6699
Phyhip
Name: phytanoyl-CoA hydroxylase interacting protein
Synonyms: PAHX-AP#1, PAHX-AP1, C630010D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105653
Homologene: 8847
Zswim5
Name: zinc finger SWIM-type containing 5
Synonyms: 4933426E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74464
Homologene: 18958
Prss50
Name: protease, serine 50
Synonyms: Tsp50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235631
Homologene: 8314
Tyk2
Name: tyrosine kinase 2
Synonyms: JTK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 54721
VEGA: 9
Homologene: 20712
Ggt1
Name: gamma-glutamyltransferase 1
Synonyms: GGT, CD224, Ggtp, dwg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14598
HGNC: HGNC:4250
Homologene: 68450
Selplg
Name: selectin, platelet (p-selectin) ligand
Synonyms: Psgl-1, Psgl1, CD162
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20345
Homologene: 2261
Baiap2l2
Name: BAI1-associated protein 2-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 207495
Homologene: 11811
Fam184a
Name: family with sequence similarity 184, member A
Synonyms: 3110012E06Rik, 4930438C08Rik, 4930589M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 75906
Homologene: 11600
Cts3
Name: cathepsin 3
Synonyms: 1600000I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 117066
VEGA: 13
Gnrhr
Name: gonadotropin releasing hormone receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14715
HGNC: HGNC:4421
Homologene: 350
Oxct2b
Name: 3-oxoacid CoA transferase 2B
Synonyms: Scot-t2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 353371
Homologene: 137359
Lrrc29
Name: leucine rich repeat containing 29
Synonyms: FBXL9, FBL9, A630024J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234684
Homologene: 133339
Nipal2
Name: NIPA-like domain containing 2
Synonyms: 9330161F08Rik, Npal2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223473
VEGA: 15
Homologene: 41586
Thnsl1
Name: threonine synthase-like 1 (bacterial)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 208967
Homologene: 32609
Scyl1
Name: SCY1-like 1 (S. cerevisiae)
Synonyms: p105, mfd, 2810011O19Rik, Ntkl, mdf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 78891
VEGA: 19
Homologene: 6947
Atg101
Name: autophagy related 101
Synonyms: 9430023L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68118
VEGA: 15
Homologene: 11072
Eif1ad14
Name: eukaryotic translation initiation factor 1A domain containing 14
Synonyms: Gm2035
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 100039076
VEGA: 12
Trbc1
Name: T cell receptor beta, constant region 1
Synonyms: Gm16802, Tcrb-C1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100125262
Gm43302
Name: predicted gene 43302
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 75,194,244 bp
  • T to A, chromosome 1 at 87,191,090 bp
  • A to G, chromosome 1 at 93,282,937 bp
  • A to T, chromosome 1 at 161,105,467 bp
  • G to T, chromosome 2 at 21,212,205 bp
  • C to A, chromosome 2 at 29,524,364 bp
  • A to G, chromosome 2 at 181,996,257 bp
  • T to C, chromosome 3 at 142,632,257 bp
  • A to G, chromosome 4 at 66,839,833 bp
  • A to G, chromosome 4 at 116,603,889 bp
  • T to C, chromosome 4 at 116,979,679 bp
  • G to A, chromosome 4 at 123,117,451 bp
  • T to C, chromosome 5 at 34,804,676 bp
  • A to G, chromosome 5 at 66,026,816 bp
  • C to T, chromosome 5 at 74,591,947 bp
  • G to T, chromosome 5 at 86,182,357 bp
  • C to T, chromosome 5 at 87,979,754 bp
  • A to G, chromosome 5 at 105,289,028 bp
  • G to T, chromosome 5 at 113,819,101 bp
  • T to C, chromosome 5 at 120,659,608 bp
  • A to T, chromosome 6 at 8,162,247 bp
  • A to C, chromosome 6 at 29,908,458 bp
  • T to C, chromosome 6 at 41,538,451 bp
  • T to C, chromosome 6 at 89,663,194 bp
  • A to G, chromosome 7 at 12,651,771 bp
  • T to A, chromosome 7 at 141,815,586 bp
  • G to T, chromosome 8 at 11,220,007 bp
  • T to C, chromosome 8 at 105,323,293 bp
  • C to A, chromosome 9 at 21,110,504 bp
  • T to C, chromosome 9 at 21,821,745 bp
  • T to C, chromosome 9 at 110,864,303 bp
  • A to T, chromosome 10 at 43,882,193 bp
  • G to A, chromosome 10 at 53,698,773 bp
  • A to T, chromosome 10 at 75,584,965 bp
  • T to C, chromosome 11 at 16,985,539 bp
  • T to A, chromosome 11 at 69,458,542 bp
  • C to T, chromosome 11 at 69,458,920 bp
  • C to T, chromosome 11 at 78,328,500 bp
  • G to A, chromosome 11 at 87,216,548 bp
  • A to G, chromosome 11 at 106,261,262 bp
  • G to A, chromosome 12 at 87,919,751 bp
  • C to A, chromosome 13 at 61,566,841 bp
  • A to G, chromosome 14 at 31,052,283 bp
  • A to G, chromosome 14 at 70,466,854 bp
  • A to G, chromosome 15 at 6,436,460 bp
  • A to C, chromosome 15 at 34,600,026 bp
  • A to T, chromosome 15 at 55,063,044 bp
  • A to G, chromosome 15 at 55,676,302 bp
  • A to G, chromosome 15 at 66,735,247 bp
  • A to G, chromosome 15 at 79,259,730 bp
  • T to A, chromosome 15 at 101,290,638 bp
  • A to T, chromosome 17 at 5,986,052 bp
  • A to T, chromosome 17 at 37,752,147 bp
  • C to A, chromosome 18 at 42,156,135 bp
  • T to A, chromosome 19 at 5,764,757 bp
  • C to T, chromosome 19 at 13,919,740 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6159 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044306-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.