Strain Name:
C57BL/6J-MtgxR6167Btlr
Stock Number:
044313-MU
Citation ID:
RRID:MMRRC_044313-MU
Other Names:
R6167 (G1)
Major Collection:

Gene Information

Camkk2
Name: calcium/calmodulin-dependent protein kinase kinase 2, beta
Synonyms: 6330570N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 207565
HGNC: HGNC:1470
Homologene: 32756
Atn1
Name: atrophin 1
Synonyms: atrophin-1, Atr1, Drpla
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13498
HGNC: HGNC:3033
Homologene: 1461
Etv1
Name: ets variant 1
Synonyms: ER81, Etsrp81
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 14009
HGNC: HGNC:3490
Homologene: 3636
Slc1a6
Name: solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Synonyms: EAAT4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20513
VEGA: 10
Homologene: 21055
Iars
Name: isoleucine-tRNA synthetase
Synonyms: E430001P04Rik, 2510016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105148
HGNC: HGNC:5330
Homologene: 5325
Sh3glb1
Name: SH3-domain GRB2-like B1 (endophilin)
Synonyms: Bif-1, Endophilin B1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 54673
Homologene: 9337
Gtf2f1
Name: general transcription factor IIF, polypeptide 1
Synonyms: 2810405L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 98053
VEGA: 17
HGNC: HGNC:4652
Homologene: 1585
Aip
Name: aryl-hydrocarbon receptor-interacting protein
Synonyms: Ara9, Xap2, D19Bwg1412e, Fkbp16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 11632
HGNC: HGNC:358
Homologene: 2959
Gabbr1
Name: gamma-aminobutyric acid (GABA) B receptor, 1
Synonyms: GABAbR1, GABAB1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 54393
HGNC: HGNC:4070
Homologene: 1132
Neurl1a
Name: neuralized E3 ubiquitin protein ligase 1A
Synonyms: Nlz, 2410129E16Rik, Neu1, Rnf67, Neur1, Neurl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18011
VEGA: 19
HGNC: HGNC:7761
Homologene: 32503
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, 2610100B16Rik, Odz3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23965
Homologene: 22673
Sec24b
Name: Sec24 related gene family, member B (S. cerevisiae)
Synonyms: SEC24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99683
Homologene: 55968
Fancm
Name: Fanconi anemia, complementation group M
Synonyms: C730036B14Rik, D12Ertd364e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104806
VEGA: 12
Homologene: 35378
Fam168b
Name: family with sequence similarity 168, member B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 214469
Homologene: 18390
Rapgef3
Name: Rap guanine nucleotide exchange factor (GEF) 3
Synonyms: 2310016P22Rik, 9330170P05Rik, Epac1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223864
Homologene: 21231
Pkd2l2
Name: polycystic kidney disease 2-like 2
Synonyms: Polycystin - L2, TRPP5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 53871
VEGA: 18
HGNC: HGNC:9012
Homologene: 22812
Large2
Name: LARGE xylosyl- and glucuronyltransferase 2
Synonyms: 5730485C17Rik, Gyltl1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228366
Homologene: 27362
Epha3
Name: Eph receptor A3
Synonyms: Tyro4, Mek4, Hek4, Hek, Cek4, End3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13837
VEGA: 16
HGNC: HGNC:3387
Homologene: 21083
Stk32a
Name: serine/threonine kinase 32A
Synonyms: YANK1, A930015B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 269019
VEGA: 18
Homologene: 65357
Ogfrl1
Name: opioid growth factor receptor-like 1
Synonyms: 2210417C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70155
Homologene: 11595
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Ahnak2
Name: AHNAK nucleoprotein 2
Synonyms: LOC382643
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 100041194
Homologene: 131081
Olfr743
Name: olfactory receptor 743
Synonyms: GA_x6K02T2N6FY-3870-3385, GA_x6K02T2N6FY-2320-2039, GA_x6K02T2PMLR-6243196-6244132, MOR106-8P, MOR106-14, Olfr265, Olfr743-ps1, Olfr264
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219019
Homologene: 74163
Shmt2
Name: serine hydroxymethyltransferase 2 (mitochondrial)
Synonyms: 2700043D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 108037
VEGA: 10
Homologene: 133984
Pxdn
Name: peroxidasin
Synonyms: 2310075M15Rik, VPO1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 69675
Homologene: 33907
Fyb2
Name: FYN binding protein 2
Synonyms: 1700024P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242594
Homologene: 52981
Kcnj2
Name: potassium inwardly-rectifying channel, subfamily J, member 2
Synonyms: IRK1, Kir2.1, Kcnf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16518
HGNC: HGNC:6263
Homologene: 20249
Plekha6
Name: pleckstrin homology domain containing, family A member 6
Synonyms: Pepp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240753
Homologene: 135779
Glyctk
Name: glycerate kinase
Synonyms: 6230410P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235582
Homologene: 14738
Abca5
Name: ATP-binding cassette, sub-family A (ABC1), member 5
Synonyms: ABC13, B930033A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217265
HGNC: HGNC:35
Homologene: 10263
Hsf4
Name: heat shock transcription factor 4
Synonyms: ldis1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 26386
HGNC: HGNC:5227
Homologene: 100128
Mak
Name: male germ cell-associated kinase
Synonyms: A930010O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17152
VEGA: 13
HGNC: HGNC:6816
Homologene: 31344
Evx2
Name: even-skipped homeobox 2
Synonyms: Evx-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14029
HGNC: HGNC:3507
Homologene: 74879
Tmpo
Name: thymopoietin
Synonyms: TP, 5630400D24Rik, LAP2, lamina-associated polypeptide 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 21917
VEGA: 10
Homologene: 31144
Aox4
Name: aldehyde oxidase 4
Synonyms: AOH2, 2310003G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71872
Homologene: 70273
Sh2b3
Name: SH2B adaptor protein 3
Synonyms: Lnk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 16923
Homologene: 36179
Dcaf7
Name: DDB1 and CUL4 associated factor 7
Synonyms: 2610037L01Rik, 1700012F10Rik, Wdr68
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71833
Homologene: 55930
Zfp948
Name: zinc finger protein 948
Synonyms: BC049807
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 381066
VEGA: 17
Slc22a23
Name: solute carrier family 22, member 23
Synonyms: 3110004L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 73102
Homologene: 41457
Piwil2
Name: piwi-like RNA-mediated gene silencing 2
Synonyms: Miwi like, mili
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 57746
VEGA: 14
Homologene: 23071
Myo18b
Name: myosin XVIIIb
Synonyms: 4932408L24Rik, 4933411E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74376
Homologene: 53435
Vill
Name: villin-like
Synonyms: Villp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22351
Homologene: 22650
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: 4931400F03Rik, eb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 74053
Homologene: 12938
Prss54
Name: protease, serine 54
Synonyms: 4931432M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 70993
Homologene: 19278
Zpld1
Name: zona pellucida like domain containing 1
Synonyms: 9430016A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239852
Homologene: 18401
Slc25a19
Name: solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
Synonyms: MUP1, DNC, 2900089E13Rik, TPC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67283
Homologene: 5982
Thoc5
Name: THO complex 5
Synonyms: PK1.3, 1700060C24Rik, Fmip, A430085L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 107829
Homologene: 37836
Hook2
Name: hook microtubule tethering protein 2
Synonyms: A630054I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 170833
Homologene: 8332
Ankrd13d
Name: ankyrin repeat domain 13 family, member D
Synonyms: 0710001P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 68423
Homologene: 27612
Trim8
Name: tripartite motif-containing 8
Synonyms: Rnf27, GERP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 93679
VEGA: 19
Homologene: 12795
Mylk2
Name: myosin, light polypeptide kinase 2, skeletal muscle
Synonyms: 9830004H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228785
Homologene: 13223
Ceacam16
Name: carcinoembryonic antigen-related cell adhesion molecule 16
Synonyms: LOC330483
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330483
Homologene: 19857
Dcaf15
Name: DDB1 and CUL4 associated factor 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212123
Homologene: 18182
P3h4
Name: prolyl 3-hydroxylase family member 4 (non-enzymatic)
Synonyms: 1110036O03Rik, Leprel4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66180
Homologene: 4713
Golga7
Name: golgi autoantigen, golgin subfamily a, 7
Synonyms: GOLGA3AP1, HSPC041, GCP16, C130038N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 57437
Homologene: 9385
Olfr387-ps1
Name: olfactory receptor 387, pseudogene 1
Synonyms: GA_x6K02T2P1NL-3823071-3824002, MOR135-17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258210
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 23,376,228 bp
  • G to A, chromosome 1 at 34,819,603 bp
  • C to T, chromosome 1 at 58,263,935 bp
  • A to G, chromosome 1 at 133,279,407 bp
  • T to A, chromosome 2 at 52,147,237 bp
  • A to C, chromosome 2 at 74,659,262 bp
  • G to A, chromosome 2 at 92,367,088 bp
  • A to G, chromosome 2 at 152,915,753 bp
  • C to T, chromosome 3 at 129,988,901 bp
  • A to T, chromosome 3 at 144,691,903 bp
  • A to G, chromosome 4 at 104,945,464 bp
  • A to T, chromosome 5 at 112,872,507 bp
  • A to T, chromosome 5 at 121,828,355 bp
  • A to G, chromosome 5 at 122,764,124 bp
  • T to C, chromosome 6 at 124,746,737 bp
  • G to A, chromosome 7 at 19,861,257 bp
  • T to C, chromosome 8 at 23,245,888 bp
  • T to C, chromosome 8 at 48,254,622 bp
  • T to C, chromosome 8 at 84,097,997 bp
  • T to C, chromosome 8 at 84,995,013 bp
  • G to A, chromosome 8 at 95,559,545 bp
  • A to G, chromosome 8 at 105,270,849 bp
  • T to A, chromosome 9 at 106,156,492 bp
  • A to T, chromosome 9 at 119,066,864 bp
  • A to G, chromosome 10 at 78,801,837 bp
  • C to T, chromosome 10 at 91,162,938 bp
  • T to C, chromosome 10 at 119,897,797 bp
  • C to T, chromosome 10 at 127,517,862 bp
  • G to A, chromosome 11 at 4,915,497 bp
  • A to G, chromosome 11 at 73,665,334 bp
  • C to A, chromosome 11 at 100,411,845 bp
  • A to T, chromosome 11 at 106,037,251 bp
  • T to A, chromosome 11 at 110,292,105 bp
  • A to G, chromosome 11 at 111,072,489 bp
  • A to G, chromosome 11 at 115,615,551 bp
  • G to A, chromosome 12 at 29,974,001 bp
  • A to T, chromosome 12 at 38,865,641 bp
  • A to T, chromosome 12 at 65,094,895 bp
  • T to C, chromosome 12 at 112,783,122 bp
  • T to A, chromosome 13 at 34,344,559 bp
  • C to A, chromosome 13 at 41,053,352 bp
  • T to A, chromosome 13 at 49,722,714 bp
  • C to A, chromosome 14 at 50,534,155 bp
  • A to C, chromosome 14 at 70,422,893 bp
  • C to A, chromosome 15 at 97,767,411 bp
  • C to T, chromosome 16 at 55,233,599 bp
  • T to C, chromosome 16 at 63,612,924 bp
  • T to G, chromosome 17 at 21,587,649 bp
  • T to C, chromosome 17 at 37,063,379 bp
  • G to T, chromosome 17 at 57,004,161 bp
  • A to G, chromosome 18 at 34,428,244 bp
  • A to T, chromosome 18 at 43,313,409 bp
  • T to G, chromosome 19 at 4,115,188 bp
  • T to C, chromosome 19 at 4,273,053 bp
  • T to C, chromosome 19 at 46,515,187 bp
  • G to C, chromosome 19 at 47,239,928 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6167 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044313-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.