Strain Name:
C57BL/6J-MtgxR6179Btlr
Stock Number:
044321-MU
Citation ID:
RRID:MMRRC_044321-MU
Other Names:
R6179 (G1)
Major Collection:

Gene Information

Ccr2
Name: chemokine (C-C motif) receptor 2
Synonyms: CC-CKR-2, CKR2B, CKR2A, CCR2B, CCR2A, CKR2, Cmkbr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12772
HGNC: HGNC:1603
Homologene: 537
Tanc1
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Synonyms: 1200003E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66860
Homologene: 18946
Phf20
Name: PHD finger protein 20
Synonyms: 6820402O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228829
Homologene: 9507
Mbd4
Name: methyl-CpG binding domain protein 4
Synonyms: Med1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17193
HGNC: HGNC:6919
Homologene: 2916
Tbce
Name: tubulin-specific chaperone E
Synonyms: 2610206D02Rik, C530005D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 70430
Homologene: 37744
Pcm1
Name: pericentriolar material 1
Synonyms: 9430077F19Rik, 2600002H09Rik, C030044G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Cbln3
Name: cerebellin 3 precursor protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56410
VEGA: 14
Homologene: 56861
Myh10
Name: myosin, heavy polypeptide 10, non-muscle
Synonyms: nonmuscle myosin heavy chain II-B, NMHC-B, SMemb, nonmuscle myosin heavy chain IIB, 9330167F11Rik, 5730504C04Rik, Myhn2, Myosin IIB, NMHC II-B, Myhn-2, myosin IIB, Fltn, Fltn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77579
HGNC: HGNC:7568
Homologene: 55941
Yeats2
Name: YEATS domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208146
VEGA: 16
Homologene: 9967
Cep131
Name: centrosomal protein 131
Synonyms: AZ1, Azi1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12009
Homologene: 7638
Gtse1
Name: G two S phase expressed protein 1
Synonyms: B99, Gtse-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 29870
VEGA: 15
Homologene: 8489
Kifbp
Name: kinesin family binding protein
Synonyms: 2510003E04Rik, Kif1bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 72320
Homologene: 9223
Dock4
Name: dedicator of cytokinesis 4
Synonyms: EST N28122, 6330411N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238130
VEGA: 12
Homologene: 56680
Mphosph10
Name: M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
Synonyms: 2810453H10Rik, 5730405D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67973
HGNC: HGNC:7213
Homologene: 134741
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Polr2b
Name: polymerase (RNA) II (DNA directed) polypeptide B
Synonyms: RPB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231329
HGNC: HGNC:9188
Homologene: 722
Chd2
Name: chromodomain helicase DNA binding protein 2
Synonyms: 2810040A01Rik, 2810013C04Rik, 5630401D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244059
HGNC: HGNC:1917
Homologene: 37462
Atp2b1
Name: ATPase, Ca++ transporting, plasma membrane 1
Synonyms: PMCA1, E130111D10Rik, 2810442I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67972
VEGA: 10
HGNC: HGNC:814
Homologene: 55597
AW209491
Name: expressed sequence AW209491
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105351
VEGA: 13
Homologene: 11439
Stra6
Name: stimulated by retinoic acid gene 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20897
Homologene: 7554
Ccdc181
Name: coiled-coil domain containing 181
Synonyms: 4930455F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74895
Homologene: 10912
Lrrc7
Name: leucine rich repeat containing 7
Synonyms: densin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242274
Homologene: 10817
Vwf
Name: Von Willebrand factor
Synonyms: B130011O06Rik, 6820430P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 22371
Homologene: 466
Msto1
Name: misato 1, mitochondrial distribution and morphology regulator
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229524
Homologene: 41228
Abca9
Name: ATP-binding cassette, sub-family A (ABC1), member 9
Synonyms: D630040K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217262
HGNC: HGNC:39
Homologene: 33332
Chl1
Name: cell adhesion molecule L1-like
Synonyms: CALL, A530023M13Rik, close homolog of L1, LICAM2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12661
HGNC: HGNC:1939
Homologene: 21314
Kcnt1
Name: potassium channel, subfamily T, member 1
Synonyms: slo2, Slack, C030030G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227632
Homologene: 11055
Pigp
Name: phosphatidylinositol glycan anchor biosynthesis, class P
Synonyms: Dcrc, Dscr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 56176
HGNC: HGNC:3046
Homologene: 32444
Shank1
Name: SH3 and multiple ankyrin repeat domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243961
Homologene: 22949
Lmbrd2
Name: LMBR1 domain containing 2
Synonyms: 9930036E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 320506
VEGA: 15
Homologene: 44696
Trim10
Name: tripartite motif-containing 10
Synonyms: Herf1, Rnf9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 19824
Homologene: 4932
Acte1
Name: actin, epsilon 1
Synonyms: LOC244239, Gm498
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 102636989
Homologene: 131918
Aox4
Name: aldehyde oxidase 4
Synonyms: AOH2, 2310003G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71872
Homologene: 70273
Spg21
Name: SPG21, maspardin
Synonyms: BM-019, GL010, ACP33, D9Wsu18e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 27965
VEGA: 9
Homologene: 9603
Vmn2r28
Name: vomeronasal 2, receptor 28
Synonyms: EG665255
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 665255
Homologene: 129605
Or1j4
Name: olfactory receptor family 1 subfamily J member 4
Synonyms: GA_x6K02T2NLDC-33544602-33545540, MOR136-13, Olfr350
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258620
HGNC: HGNC:8211
Homologene: 64897
Prss3
Name: protease, serine 3
Synonyms: Tb, TRY4, MTG, mesotrypsin, Try3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 22073
HGNC: HGNC:9486
Homologene: 88408
Ppig
Name: peptidyl-prolyl isomerase G (cyclophilin G)
Synonyms: SRCyp, B230312B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228005
Homologene: 3520
Edil3
Name: EGF-like repeats and discoidin I-like domains 3
Synonyms: Del1, developmental endothelial locus-1, Del-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13612
HGNC: HGNC:3173
Homologene: 21166
Nup43
Name: nucleoporin 43
Synonyms: p42, 2610529I12Rik, 2610016K01Rik, 43kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 69912
Homologene: 11639
4930590J08Rik
Name: RIKEN cDNA 4930590J08 gene
Synonyms: LOC381798
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381798
Homologene: 49985
Cpeb3
Name: cytoplasmic polyadenylation element binding protein 3
Synonyms: 4831444O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 208922
Homologene: 40992
Cry2
Name: cryptochrome 2 (photolyase-like)
Synonyms: D130054K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12953
HGNC: HGNC:2385
Homologene: 56466
Endod1
Name: endonuclease domain containing 1
Synonyms: 2210414F18Rik, 2310067E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71946
VEGA: 9
Homologene: 12425
Tmem106b
Name: transmembrane protein 106B
Synonyms: 6430519M21Rik, 5830455K21Rik, 2310036D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71900
Homologene: 56806
Spns3
Name: spinster homolog 3
Synonyms: 9830002I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77577
Homologene: 45648
Zfp40
Name: zinc finger protein 40
Synonyms: NTfin12, Zfp-40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22700
Homologene: 136312
Crb2
Name: crumbs family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241324
Homologene: 45474
Trim31
Name: tripartite motif-containing 31
Synonyms: HCG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224762
Homologene: 17137
Fpr3
Name: formyl peptide receptor 3
Synonyms: Lxa4r, LXA4-R, Fprl1, Fpr-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14294
B930094E09Rik
Name: RIKEN cDNA B930094E09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
4930426L09Rik
Name: RIKEN cDNA 4930426L09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74629
VEGA: 2
Fam134c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 58,231,503 bp
  • A to T, chromosome 1 at 164,279,918 bp
  • T to C, chromosome 2 at 18,998,842 bp
  • G to A, chromosome 2 at 25,893,180 bp
  • T to C, chromosome 2 at 36,850,834 bp
  • T to C, chromosome 2 at 37,790,257 bp
  • A to G, chromosome 2 at 59,842,976 bp
  • T to A, chromosome 2 at 69,750,127 bp
  • C to T, chromosome 2 at 92,413,842 bp
  • T to A, chromosome 2 at 156,298,653 bp
  • C to A, chromosome 3 at 88,910,947 bp
  • T to G, chromosome 3 at 158,353,432 bp
  • T to C, chromosome 5 at 77,320,977 bp
  • T to C, chromosome 6 at 13,084,253 bp
  • G to A, chromosome 6 at 41,375,126 bp
  • T to C, chromosome 6 at 91,942,330 bp
  • A to T, chromosome 6 at 103,683,243 bp
  • A to G, chromosome 6 at 115,845,425 bp
  • G to A, chromosome 6 at 125,649,289 bp
  • G to A, chromosome 7 at 5,488,004 bp
  • T to C, chromosome 7 at 44,357,206 bp
  • A to G, chromosome 7 at 64,378,781 bp
  • A to G, chromosome 7 at 73,444,323 bp
  • A to G, chromosome 7 at 143,871,787 bp
  • T to A, chromosome 8 at 41,283,632 bp
  • T to C, chromosome 9 at 14,357,461 bp
  • A to G, chromosome 9 at 58,135,169 bp
  • T to C, chromosome 9 at 65,468,808 bp
  • A to C, chromosome 9 at 124,105,971 bp
  • T to C, chromosome 10 at 7,678,673 bp
  • G to A, chromosome 10 at 62,563,250 bp
  • C to T, chromosome 10 at 99,022,829 bp
  • G to A, chromosome 11 at 68,802,153 bp
  • A to G, chromosome 11 at 72,499,523 bp
  • G to A, chromosome 11 at 101,103,895 bp
  • T to C, chromosome 11 at 110,134,254 bp
  • T to C, chromosome 11 at 120,066,011 bp
  • T to A, chromosome 12 at 8,005,060 bp
  • A to G, chromosome 12 at 40,731,869 bp
  • T to G, chromosome 13 at 14,019,777 bp
  • T to G, chromosome 13 at 14,637,083 bp
  • A to T, chromosome 13 at 88,821,989 bp
  • G to T, chromosome 14 at 55,884,060 bp
  • T to G, chromosome 15 at 9,149,175 bp
  • T to G, chromosome 15 at 85,868,957 bp
  • C to T, chromosome 16 at 20,214,475 bp
  • T to C, chromosome 16 at 94,370,367 bp
  • G to A, chromosome 17 at 17,970,657 bp
  • C to A, chromosome 17 at 23,178,380 bp
  • A to G, chromosome 17 at 36,877,031 bp
  • T to A, chromosome 17 at 36,909,609 bp
  • G to C, chromosome 18 at 31,609,858 bp
  • A to G, chromosome 19 at 37,088,453 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6179 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044321-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.